LOCUS       NM_131910                664 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus dynein light chain roadblock-type 1 (Dynlrb1),
            mRNA.
ACCESSION   NM_131910
VERSION     NM_131910.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Islam,M.A., Sharif,S.R., Lee,H., Seog,D.H. and Moon,I.S.
  TITLE     N-acetyl-D-glucosamine kinase interacts with dynein light-chain
            roadblock type 1 at Golgi outposts in neuronal dendritic branch
            points
  JOURNAL   Exp Mol Med 47 (8), e177 (2015)
   PUBMED   26272270
  REMARK    GeneRIF: The interaction between NAGK and Dynlrb1 frequently occurs
            at dendritic branch points.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  AUTHORS   Allan,V.J.
  TITLE     Cytoplasmic dynein
  JOURNAL   Biochem Soc Trans 39 (5), 1169-1178 (2011)
   PUBMED   21936784
  REMARK    Review article
REFERENCE   3  (bases 1 to 664)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   4  (bases 1 to 664)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 664)
  AUTHORS   Nikulina,K., Patel-King,R.S., Takebe,S., Pfister,K.K. and King,S.M.
  TITLE     The Roadblock light chains are ubiquitous components of cytoplasmic
            dynein that form homo- and heterodimers
  JOURNAL   Cell Motil Cytoskeleton 57 (4), 233-245 (2004)
   PUBMED   14752807
REFERENCE   6  (bases 1 to 664)
  AUTHORS   Jiang,J., Yu,L., Huang,X., Chen,X., Li,D., Zhang,Y., Tang,L. and
            Zhao,S.
  TITLE     Identification of two novel human dynein light chain genes, DNLC2A
            and DNLC2B, and their expression changes in hepatocellular
            carcinoma tissues from 68 Chinese patients
  JOURNAL   Gene 281 (1-2), 103-113 (2001)
   PUBMED   11750132
REFERENCE   7  (bases 1 to 664)
  AUTHORS   Ye,F., Zangenehpour,S. and Chaudhuri,A.
  TITLE     Light-induced down-regulation of the rat class 1 dynein-associated
            protein robl/LC7-like gene in visual cortex
  JOURNAL   J Biol Chem 275 (35), 27172-27176 (2000)
   PUBMED   10816553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Mar 14, 2022 this sequence version replaced NM_131910.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CN541828.1, FM080737.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-61                JAXUCZ010000003.1  164203239-164203299
            62-137              JAXUCZ010000003.1  164213213-164213288
            138-305             JAXUCZ010000003.1  164219850-164220017
            306-664             JAXUCZ010000003.1  164224051-164224409
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..664
                     /gene="Dynlrb1"
                     /gene_synonym="Dncl2a; km23"
                     /note="dynein light chain roadblock-type 1"
                     /db_xref="GeneID:170714"
                     /db_xref="RGD:619910"
     exon            1..61
                     /gene="Dynlrb1"
                     /gene_synonym="Dncl2a; km23"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..349
                     /gene="Dynlrb1"
                     /gene_synonym="Dncl2a; km23"
                     /note="BLP; robl/LC7-like protein; dynein-associated
                     protein Km23; dynein light chain 2A, cytoplasmic;
                     bithoraxoid-like protein; dynein-associated protein RKM23;
                     dynein, cytoplasmic, light chain 2A"
                     /codon_start=1
                     /product="dynein light chain roadblock-type 1"
                     /protein_id="NP_571985.1"
                     /db_xref="GeneID:170714"
                     /db_xref="RGD:619910"
                     /translation="MAEVEETLKRLQSQKGVQGIIVVNTEGIPIKSTMDNPTTTQYAN
                     LMHNFILKARSTVREIDPQNDLTFLRIRSKKNEIMVAPDKDYFLIVIQNPTE"
     exon            62..137
                     /gene="Dynlrb1"
                     /gene_synonym="Dncl2a; km23"
                     /inference="alignment:Splign:2.1.0"
     exon            138..305
                     /gene="Dynlrb1"
                     /gene_synonym="Dncl2a; km23"
                     /inference="alignment:Splign:2.1.0"
     exon            306..664
                     /gene="Dynlrb1"
                     /gene_synonym="Dncl2a; km23"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaagggcgg ggaactcggc tgagtgttgg cgattcggag ctgctgtgtc tgtccgagat
       61 ggcagaggtg gaggaaacac tcaagaggct tcagagccag aaaggagtgc agggcatcat
      121 cgtggtgaac acagaaggca ttcccatcaa gagcacaatg gacaatccca ccacgacaca
      181 gtacgccaac ctcatgcaca acttcatctt aaaggctcgg agcactgtgc gtgagattga
      241 cccccagaat gacctaacct tccttcgaat tcgctccaag aaaaatgaaa ttatggtggc
      301 accagataaa gactatttcc tgattgtgat tcagaatcca actgaataag gcactgtctt
      361 ggcttcctgt gtcattcctt aatttaatgt cccccgagaa taatagcgtt aatcatgtca
      421 gtgggcacat gtggctgcct ggagccatgc agaccttggc attggtgaag ggtagctctg
      481 cccaccccac caaggagtgc ctctgatgat ccggtcagtc cccagaagag ctcagttctc
      541 tctccaggct ttggaatgag agctcttgat aagcccacag ccagcttcct tctaaccttc
      601 atttcacttt gtcccccttg gaagctgttt ttgttttttt aaactaaaaa taacttcaac
      661 cccc
//
