LOCUS       NM_001005542            1882 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus dynein 2 intermediate chain 2 (Dync2i2), mRNA.
ACCESSION   NM_001005542 XM_003749435 XM_003753691 XM_216032
VERSION     NM_001005542.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1882)
  AUTHORS   Gholkar,A.A., Senese,S., Lo,Y.C., Capri,J., Deardorff,W.J.,
            Dharmarajan,H., Contreras,E., Hodara,E., Whitelegge,J.P.,
            Jackson,P.K. and Torres,J.Z.
  TITLE     Tctex1d2 associates with short-rib polydactyly syndrome proteins
            and is required for ciliogenesis
  JOURNAL   Cell Cycle 14 (7), 1116-1125 (2015)
   PUBMED   25830415
REFERENCE   2  (bases 1 to 1882)
  AUTHORS   Asante,D., Stevenson,N.L. and Stephens,D.J.
  TITLE     Subunit composition of the human cytoplasmic dynein-2 complex
  JOURNAL   J Cell Sci 127 (Pt 21), 4774-4787 (2014)
   PUBMED   25205765
REFERENCE   3  (bases 1 to 1882)
  AUTHORS   Goggolidou,P., Stevens,J.L., Agueci,F., Keynton,J., Wheway,G.,
            Grimes,D.T., Patel,S.H., Hilton,H., Morthorst,S.K., DiPaolo,A.,
            Williams,D.J., Sanderson,J., Khoronenkova,S.V., Powles-Glover,N.,
            Ermakov,A., Esapa,C.T., Romero,R., Dianov,G.L., Briscoe,J.,
            Johnson,C.A., Pedersen,L.B. and Norris,D.P.
  TITLE     ATMIN is a transcriptional regulator of both lung morphogenesis and
            ciliogenesis
  JOURNAL   Development 141 (20), 3966-3977 (2014)
   PUBMED   25294941
REFERENCE   4  (bases 1 to 1882)
  AUTHORS   Schmidts,M., Vodopiutz,J., Christou-Savina,S., Cortes,C.R.,
            McInerney-Leo,A.M., Emes,R.D., Arts,H.H., Tuysuz,B., D'Silva,J.,
            Leo,P.J., Giles,T.C., Oud,M.M., Harris,J.A., Koopmans,M.,
            Marshall,M., Elcioglu,N., Kuechler,A., Bockenhauer,D., Moore,A.T.,
            Wilson,L.C., Janecke,A.R., Hurles,M.E., Emmet,W., Gardiner,B.,
            Streubel,B., Dopita,B., Zankl,A., Kayserili,H., Scambler,P.J.,
            Brown,M.A., Beales,P.L., Wicking,C., Duncan,E.L. and Mitchison,H.M.
  CONSRTM   UK10K
  TITLE     Mutations in the gene encoding IFT dynein complex component WDR34
            cause Jeune asphyxiating thoracic dystrophy
  JOURNAL   Am J Hum Genet 93 (5), 932-944 (2013)
   PUBMED   24183451
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1 and BC082103.1.
            
            On or before Mar 1, 2014 this sequence version replaced
            XM_003749435.2, XM_003753691.2, NM_001005542.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.15987.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                JAXUCZ010000003.1  33719918-33719960   c
            44-216              JAXUCZ010000003.1  33719302-33719474   c
            217-1873            BC082103.1         1-1657
            1874-1882           JAXUCZ010000003.1  33703882-33703890   c
FEATURES             Location/Qualifiers
     source          1..1882
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..1882
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /note="dynein 2 intermediate chain 2"
                     /db_xref="GeneID:296618"
                     /db_xref="RGD:1359465"
     exon            1..43
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /inference="alignment:Splign:2.1.0"
     exon            44..358
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /inference="alignment:Splign:2.1.0"
     CDS             173..1786
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /note="WD repeat-containing protein 34; WD repeat domain
                     34"
                     /codon_start=1
                     /product="cytoplasmic dynein 2 intermediate chain 2"
                     /protein_id="NP_001005542.2"
                     /db_xref="GeneID:296618"
                     /db_xref="RGD:1359465"
                     /translation="MAISASPRPFPRVGSARVAALAAGGAGGGERRGRPAPLQDETLG
                     VASVPSQWRSVQGIRGEPKSCQTAGIATAEASAQARTHADAQVQTEAPEEPAAVAPVS
                     QYDTLRLAAFLRRVEAMVVRELNNNWQSHAFDGYEVNWTEQQQTVSCLHTLGYPPAQG
                     QGLHVTGISWNTTGSVLACAYGRLDDGDWGTLKSYVCTWNLDRQGLNPHQPSVVVEVP
                     SAVMCLAFHPIQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWL
                     PEPRHSHRFQVLSAATDGRVLLWRGSGAGQLRLSKGFALAVQQLPRSTKLKKPPRGET
                     EVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLAAEAAALTRMPSSVPLRAPVQFTFSPH
                     GGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPL
                     VFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGVV
                     KVWQLSTAFTEQGPREAEDLDQLEAEIAT"
     exon            359..610
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /inference="alignment:Splign:2.1.0"
     exon            611..720
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /inference="alignment:Splign:2.1.0"
     exon            721..878
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /inference="alignment:Splign:2.1.0"
     exon            879..988
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1156
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1389
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1547
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1882
                     /gene="Dync2i2"
                     /gene_synonym="Wdr34"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacctggggc aatctatcat cgagctcaac ttcatcccgt gcgacggtgc tgcaaccagt
       61 tcaaaaacgg cgcagacagc ttcacttcct cttttcggac ttccgcttgc ggtagcgaaa
      121 cccgcagagg tcatgtttca gagcgcaggc gcgaaagggt ggggccgtcg ccatggcaat
      181 tagcgcatcg cccaggcctt ttccgcgggt tggaagcgcc agagttgctg cgctggctgc
      241 tggcggggct ggcggcgggg agcggcgggg acggcccgcg cctctgcagg atgagaccct
      301 gggcgtggcg tctgtgccgt ctcagtggag gagtgtgcag ggcatccgtg gggaaccgaa
      361 aagttgccag acagcgggca ttgccaccgc agaggcatct gcgcaggccc ggacacatgc
      421 agatgcccag gtgcagacag aggctcccga ggagccagcg gctgtggctc ctgtgtccca
      481 gtacgacacc ctcagactcg cagcctttct ccggagggtg gaggccatgg tcgtccggga
      541 gctgaacaac aactggcaga gccatgcctt cgatggctat gaggtcaact ggactgagca
      601 gcagcagacg gtgtcctgtc tgcacaccct gggctacccc ccagcccaag ggcagggtct
      661 gcatgtgact ggcatttcct ggaacaccac aggctctgtg ctggcctgcg cctatggtcg
      721 gctagacgat ggagactggg gtacactcaa gtcctatgtg tgcacctgga acctggaccg
      781 ccaaggcctg aacccccatc agccatcagt agtggtggag gtgcccagtg ctgtcatgtg
      841 cctggccttt catcccatac agccctccca cattgcaggg gggctgtaca gtggtgaagt
      901 gctggtgtgg gacatgagcc gacctgagga cccactgctt tggcgtacag gtctgacaga
      961 tgacactcac acagacccag tgtatcaggt gctatggttg ccggaacccc ggcatagcca
     1021 ccgcttccag gtcctgagtg cggccacgga tgggagggtg ctgctctgga ggggcagtgg
     1081 ggctggccag ctgcgcctct ccaagggctt tgccctggct gtgcagcagc tgccccggag
     1141 caccaagctg aagaagcctc cccgaggaga gactgaggtg ggggtgacat cggtggcctt
     1201 ctccagcttt gactccagcc ttttcgttct gggcacagaa ggtggcttcc ccctcaagtg
     1261 ctccctggca gcggaagcag ctgctctcac tcggatgccc agctccgtgc cacttagggc
     1321 cccggtgcag ttcaccttct ctccccatgg tggccctgtg tactctgtga gctgctcccc
     1381 ttttcacagg aatctcttcc tgagtgctgg gaccgatggc cacgtccacc tgtactccat
     1441 gctgcaggcc cagcctctca cctcactgca gctctctcac aagtacctgt ttgctgtgcg
     1501 ctggtcccct gtgcgcccct tggtttttgc tgctgcttct ggggaaggtg atgtacaact
     1561 gtttgacctc cagaaaagct cacagaaacc cacggtttcc ataacacaaa cccaggatgg
     1621 aagtcctgtc tactgtcttg agtttaacag ccagcagacg cagctcttgg ctgctggcga
     1681 tgctaagggc gtggtcaaag tgtggcagct gagcacagcc ttcacggaac aaggaccccg
     1741 agaggccgag gacttggacc agctggaagc tgaaatcgct acctgagagc ctggaggagc
     1801 agcagggtgg ggtgtctcct gcggccactg gggctggctg agtgctaagc aggataaaga
     1861 ggagcaaagc ctgtagggag aa
//
