LOCUS       NM_001191773            3192 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus dynein 2 intermediate chain 1 (Dync2i1), mRNA.
ACCESSION   NM_001191773 XM_234706
VERSION     NM_001191773.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3192)
  AUTHORS   Gholkar,A.A., Senese,S., Lo,Y.C., Capri,J., Deardorff,W.J.,
            Dharmarajan,H., Contreras,E., Hodara,E., Whitelegge,J.P.,
            Jackson,P.K. and Torres,J.Z.
  TITLE     Tctex1d2 associates with short-rib polydactyly syndrome proteins
            and is required for ciliogenesis
  JOURNAL   Cell Cycle 14 (7), 1116-1125 (2015)
   PUBMED   25830415
REFERENCE   2  (bases 1 to 3192)
  AUTHORS   Asante,D., Stevenson,N.L. and Stephens,D.J.
  TITLE     Subunit composition of the human cytoplasmic dynein-2 complex
  JOURNAL   J Cell Sci 127 (Pt 21), 4774-4787 (2014)
   PUBMED   25205765
REFERENCE   3  (bases 1 to 3192)
  AUTHORS   McInerney-Leo,A.M., Schmidts,M., Cortes,C.R., Leo,P.J., Gener,B.,
            Courtney,A.D., Gardiner,B., Harris,J.A., Lu,Y., Marshall,M.,
            Scambler,P.J., Beales,P.L., Brown,M.A., Zankl,A., Mitchison,H.M.,
            Duncan,E.L. and Wicking,C.
  CONSRTM   UK10K Consortium
  TITLE     Short-rib polydactyly and Jeune syndromes are caused by mutations
            in WDR60
  JOURNAL   Am J Hum Genet 93 (3), 515-523 (2013)
   PUBMED   23910462
REFERENCE   4  (bases 1 to 3192)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   5  (bases 1 to 3192)
  AUTHORS   Ishikawa,H., Thompson,J., Yates,J.R. 3rd and Marshall,W.F.
  TITLE     Proteomic analysis of mammalian primary cilia
  JOURNAL   Curr Biol 22 (5), 414-419 (2012)
   PUBMED   22326026
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            [WARNING] On Oct 17, 2024 this sequence was replaced by
            NM_001191773.2.
            
            On Jul 17, 2010 this sequence version replaced XM_234706.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.37765.1,
                                           SRR26643294.26979.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                JAXUCZ010000006.1  143331560-143331574 c
            16-69               JAXUCZ010000006.1  143326052-143326105 c
            70-502              JAXUCZ010000006.1  143324622-143325054 c
            503-594             JAXUCZ010000006.1  143323226-143323317 c
            595-903             JAXUCZ010000006.1  143319568-143319876 c
            904-981             JAXUCZ010000006.1  143318267-143318344 c
            982-1198            JAXUCZ010000006.1  143317577-143317793 c
            1199-1301           JAXUCZ010000006.1  143312996-143313098 c
            1302-1431           JAXUCZ010000006.1  143305352-143305481 c
            1432-1543           JAXUCZ010000006.1  143304570-143304681 c
            1544-1632           JAXUCZ010000006.1  143303686-143303774 c
            1633-1762           JAXUCZ010000006.1  143298811-143298940 c
            1763-1935           JAXUCZ010000006.1  143295310-143295482 c
            1936-2098           JAXUCZ010000006.1  143294208-143294370 c
            2099-2212           JAXUCZ010000006.1  143288874-143288987 c
            2213-2274           JAXUCZ010000006.1  143288714-143288775 c
            2275-2326           JAXUCZ010000006.1  143288265-143288316 c
            2327-2387           JAXUCZ010000006.1  143286686-143286746 c
            2388-2487           JAXUCZ010000006.1  143283488-143283587 c
            2488-2619           JAXUCZ010000006.1  143283180-143283311 c
            2620-2843           JAXUCZ010000006.1  143281632-143281855 c
            2844-3192           JAXUCZ010000006.1  143276441-143276789 c
FEATURES             Location/Qualifiers
     source          1..3192
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q33"
     gene            1..3192
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /note="dynein 2 intermediate chain 1"
                     /db_xref="GeneID:314523"
                     /db_xref="RGD:1306493"
     CDS             1..3012
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /note="WD repeat-containing protein 60; WD repeat domain
                     60"
                     /codon_start=1
                     /product="cytoplasmic dynein 2 intermediate chain 1"
                     /protein_id="NP_001178702.1"
                     /db_xref="GeneID:314523"
                     /db_xref="RGD:1306493"
                     /translation="MEPGKRRTKDDTWKADDLRRHLKAAQSGSPKEEKKLREKKMHKD
                     SELGTPEYREHKSRDPDREARHKEKTVERDLYSSTEHPRGERDRERHKERRKDGKDRE
                     KDKLKERHRDQEAEKSHSRGKDREREKDRRVRKEELRQSMAYHDLLGRDVRGRQMLEK
                     VEKKVHIASKLRMEERERRDEDSERVDEDRERRYRERKLQYGDSKENPLNYWLYKEDG
                     EKKHRKVKDADRERKHREKSSTREKKDRHSKEKGSSLSDREIEDRHREKRHKDGLHYD
                     EERRRSHADKKERSLKEEHRKRESKEPEKEDNGLEATGADEYLPNLEDDFVDYEDDFE
                     VCDGDDDSNNEHEAKEKADELPLAQKREIQEIQKAISAENERVGELSLKMFQKQGRAE
                     NTKEPWADANDSTSRTPVCGIFVDFATASHRQKSRSQALKQKTRSTKLLRLIDLDFSF
                     TFSLLDLPPVNEYDMYIRNFGKKNTKQAYVQYNEDNVERDIQTEDIETREVWTQHPGE
                     GTVVSGGSEEKDFSDVTVVPKIDTPRLSNFLRAACQVVAVLLEEDRLAAGPSWIPRAQ
                     DKALNISDSSSQLNTSLPFLQSRKVSCLHASRVQRQTVVSVHDLPEKAFAPSLDSRHL
                     LCVWDIWQPSGPQKVLICESKVTCCCFSPLKAFLLFAGTVHGSVVVWDLREDSRIHHY
                     VRLSSCFWAFRTPTFSTDGILTSVNHRSPLQAIEPVATSAYKKQSFVLSPFSTQEEMA
                     GLSFHIASLDESGVLNVWVVVELPKADISGSMSDLGLIPGGRIKLVHSTVIQLGHSLS
                     HKDGELWGSTQTLSVKFLPSDPNHFVVGTDMGLISHSTRQDWRVSPKVFKPQQHGVRP
                     IKVNVIDFSPFEETVFLAGCSDGSIRLHQLTSERPIMQWDNSTSGRSVTSLQWSPTRP
                     AVFLVQDDASRIYVWDLLENDLGPVAQQPISPDKLVAMTIVGEPEKTSGSFVALVLAR
                     TSGTVDIQNLKRRWTTPAADEHSQLHLLLQK"
     exon            1..15
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            16..69
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            70..502
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            503..594
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            595..903
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            904..981
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            982..1198
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1301
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1431
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..1543
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..1632
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..1762
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1935
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..2098
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            2099..2212
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2274
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            2275..2326
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            2327..2387
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            2388..2487
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            2488..2619
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            2620..2843
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
     exon            2844..3192
                     /gene="Dync2i1"
                     /gene_synonym="RGD1306493; Wdr60"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggagcctg ggaagagaag aaccaaagat gatacttgga aagcagatga cctcagaaga
       61 caccttaagg ctgcacaatc aggtagtccc aaggaagaga agaaactcag agaaaagaag
      121 atgcacaagg actcagagtt gggcactcct gaatacagag agcacaagag cagggaccca
      181 gaccgagagg cccggcacaa ggagaagaca gtggagagag acctgtacag ctccacagaa
      241 catccccgtg gggaacgaga ccgggagagg cacaaggaaa ggaggaaaga tgggaaagac
      301 cgtgagaaag acaagctgaa agagagacat cgagaccaag aagcagagaa gtctcatagt
      361 cgcggcaagg acagagagag agagaaagac agaagggtca ggaaagaaga gctcaggcag
      421 tccatggcct accatgacct cctgggtcga gatgtgcgtg gccggcagat gctggagaaa
      481 gtggaaaaga aagttcatat agcaagtaaa ttacgaatgg aggaaagaga aaggagagac
      541 gaagactctg aaagagtgga tgaagataga gaaagaagat accgagaacg gaagctgcag
      601 tatggtgaca gtaaggagaa tcccctgaat tactggctgt ataaggagga cggtgaaaag
      661 aagcacagga aggtgaaaga tgcagatcgg gagaggaagc accgagagaa aagcagcaca
      721 agggagaaaa aagacagaca ctcaaaggag aaggggagct ctctgtctga cagggaaata
      781 gaagacagac acagagagaa gcggcacaag gacggactgc attatgatga ggagaggcgc
      841 cgaagtcacg cggataaaaa agagagatct ctgaaagaag agcacaggaa aagggagtca
      901 aaggaacctg aaaaggaaga caatggttta gaggctactg gggctgatga gtatctgccc
      961 aacttagaag atgattttgt ggattatgaa gacgactttg aggtttgtga tggagacgat
     1021 gacagcaaca atgagcacga agctaaagag aaagccgacg agcttcctct ggcccagaaa
     1081 agggaaatac aggagattca aaaggcgatc agtgcagaga acgaaagggt tggcgagtta
     1141 tctttgaaaa tgtttcagaa gcaaggtcgg gcagagaaca cgaaggagcc ctgggcagat
     1201 gcaaatgatt ccacttctag aacccctgtt tgtggaattt ttgtggattt tgcaacagct
     1261 tcacatcgtc agaagagtag gagtcaggcc ctcaagcaaa agacacgaag tacaaaactg
     1321 ctccggctta ttgacttaga cttttccttc accttttctc tcttggacct accaccagta
     1381 aatgaatatg acatgtacat taggaacttt gggaaaaaaa ataccaagca ggcatatgtt
     1441 cagtataatg aagataatgt tgagagagac attcagactg aagatataga aaccagggaa
     1501 gtatggaccc aacacccagg agaaggcact gtcgtatctg gaggtagcga agaaaaggac
     1561 ttctctgatg tcacagttgt accgaagatt gacactccga ggttgtctaa ctttctccgg
     1621 gcagcatgcc aggtggttgc tgttttgctt gaagaggacc gtttggcagc tggacccagc
     1681 tggattccca gggctcaaga caaagctctg aacatcagtg acagctcctc tcaactgaac
     1741 acaagcctac cgtttcttca gagtcggaaa gtatcctgtt tgcatgcatc tcgagttcag
     1801 aggcagaccg tggtctctgt tcatgactta cctgaaaagg cttttgctcc gtctctggat
     1861 agcaggcacc ttctctgtgt gtgggatatt tggcagcctt cagggcccca gaaggttctg
     1921 atatgtgagt caaaggtcac ttgctgctgc tttagccctt taaaagcatt tctgctgttt
     1981 gcgggaacag tgcatggctc tgtggttgtg tgggacttaa gagaagactc caggatacac
     2041 cattacgtga gactgagcag ctgtttctgg gctttcagga ccccaacatt ctccactgat
     2101 ggaatcctca catcggtgaa ccaccgaagc cctcttcaag ccatagagcc ggttgccaca
     2161 tctgcctaca aaaaacagag ctttgtgctt tcaccctttt ctactcaaga agaaatggca
     2221 ggcttgtcat ttcacatcgc ttccctggat gagagtgggg ttctcaatgt atgggtggtt
     2281 gttgaattac caaaagcaga tatctcaggt tcaatgagtg atttaggtct gatacctgga
     2341 gggaggatca agttggtgca cagtactgta atccaactgg gccacagtct ttctcataaa
     2401 gatggtgaac tgtgggggtc cacacagaca ctgagtgtca aattcctgcc ttcggatcct
     2461 aatcacttcg ttgttggcac cgacatggga cttataagtc acagtaccag gcaagattgg
     2521 agagtctctc ccaaggtgtt caaacctcag caacatggtg tcagaccaat aaaagttaac
     2581 gtgattgatt tttcaccgtt cgaagaaaca gtattcttgg ctggctgttc cgatggaagc
     2641 atcaggctac accagctgac gtctgagagg cccatcatgc agtgggacaa cagcaccagt
     2701 ggccgctctg tcaccagtct gcagtggtcc ccgacaaggc ccgctgtgtt cctggtccag
     2761 gatgatgcgt ctaggatcta tgtttgggat cttcttgaga atgacctggg tcctgtggcc
     2821 cagcagccca tctctccaga taagcttgtg gccatgacta tcgtggggga acccgagaag
     2881 accagtggta gctttgtggc cctggtgttg gccaggacct ctggtacagt cgacatccag
     2941 aacctgaaga ggcggtggac caccccggca gcagatgagc atagccagct gcatctgctt
     3001 cttcagaaat gaagacctaa tgtcaggaga atgatgggta catgagcctt gattacagat
     3061 ggatcccttc actctgtgtc tatgtgactt tgtgtacata gagtgtgtat attctgtaca
     3121 taatttgctt tagaagagca gtgctttggt attcccagga aataaatcac tatttttaat
     3181 ggaaacagtg aa
//
