LOCUS       XM_039094803            4984 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus dual specificity phosphatase 4
            (Dusp4), transcript variant X1, mRNA.
ACCESSION   XM_039094803
VERSION     XM_039094803.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051351.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039094803.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4984
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4984
                     /gene="Dusp4"
                     /gene_synonym="Mkp-2; Mkp2"
                     /note="dual specificity phosphatase 4; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 13 ESTs, 1 long SRA read, 19 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 3 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:60587"
                     /db_xref="RGD:620625"
     CDS             617..1804
                     /gene="Dusp4"
                     /gene_synonym="Mkp-2; Mkp2"
                     /codon_start=1
                     /product="dual specificity protein phosphatase 4 isoform
                     X1"
                     /protein_id="XP_038950731.1"
                     /db_xref="GeneID:60587"
                     /db_xref="RGD:620625"
                     /translation="MVTMEELREMDCSVLKRLMNRDENGGSAGSSGGSHGALGLLSGG
                     KCLLLDCRPFLAHSAGYIRGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGL
                     YSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCS
                     KTKALAAIPPPVPPSTNESLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDML
                     DALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGR
                     VLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQ
                     VLTTSCAAEAASPSGPLRERGKATPTPTSQFVFSFPVSVGVHAAPSNLPYLHSPITTS
                     PSC"
ORIGIN      
        1 tgtcttgaaa aacctaacag caacaataga caaacaaaca aacaacacca ccaaacaaaa
       61 aacccaaaca aaacacgatg atctactatt tgaaagggaa tgacgactct ctccagcatt
      121 ggcatagact aagagtccac tcaaggtgtt gaagatttcc actgcctccc aatcttgact
      181 taaggatcag agatgggtca gacagagaca tgcgaaggac atattgtgga gatctttcct
      241 gcttgaagcc tgagttggcc tccaggtctc cctagtatat accattagtg caggtaaaaa
      301 ggatgtttca tgtgtagttc agagtaagaa gcaaggctcc agaggccagg gaatccaccc
      361 agcgtctatc cactgccact gtgattattc acttatcagt gatctttttt ttaagatgat
      421 tgccccctgc aacgcccact ggacccagaa aagggtgttg gggacttcag agtgcagaga
      481 gtctgtagga agccttgaaa atgggagttg gaggtgatct ctggagagcc gctctgcaga
      541 aaacaaagca aagcctagct ggcttgggtg cccttggtct tctccggctc cccagctgct
      601 gtgctttgcc ggcgacatgg tgacgatgga ggaactgcgg gagatggact gcagcgtgct
      661 caaaaggctg atgaaccgag atgagaacgg cggcagcgcg ggcagcagcg gcggcagcca
      721 cggcgccctg gggctgctga gcggcggcaa gtgcttgctg ctggactgca ggccgtttct
      781 ggctcacagc gcgggctaca tccgaggctc ggtgaacgtg cgctgcaata ccatcgtgcg
      841 gcggagggcc aagggctccg tgagcctgga gcagattctg cccgccgagg aagaggtgcg
      901 cgcccgcctg cgctctggcc tctactcggc tgtcatcgtc tacgatgagc gcagcccgcg
      961 cgccgagagt ctccgggagg acagcacagt gtcgctggtc gtgcaggcgt tgcgccggaa
     1021 cgcggagcgc acagacatct gcctgcttaa aggtggctat gagaggtttt cttctgagta
     1081 cccagaattc tgctctaaaa ctaaggccct ggccgccatc ccaccccccg tacctcccag
     1141 cacaaatgag tccttggatc tgggctgcag ctcctgtggg accccactgc acgaccaggg
     1201 gggtcctgtg gagatccttc ctttcctcta cctcggcagt gcctaccacg ctgcccgcag
     1261 ggacatgctt gatgccctgg ggatcacggc tctactgaat gtctcctcag actgccccaa
     1321 tcactttgag ggacattacc agtacaagtg catcccggta gaagataacc acaaggctga
     1381 catcagctcc tggttcatgg aagccatcga atacatagac gcagtgaagg actgccgagg
     1441 gcgagtgctg gttcactgcc aggccggcat ctctagatca gccaccatct gcctggccta
     1501 cctgatgatg aagaaacggg tgaggctgga ggaggctttc gagttcgtca agcagcgccg
     1561 tagcatcatc tcgcccaact tcagcttcat gggccagttg ctgcagttcg agtctcaggt
     1621 gctcaccacg tcctgcgcag cggaggccgc cagcccttcc gggcccctgc gggagagggg
     1681 gaaggccact cccaccccca cctcgcagtt cgtcttcagc ttccccgtgt ccgtgggtgt
     1741 gcacgcggct cccagtaacc tgccgtacct gcacagcccc atcaccacct cccccagctg
     1801 ttaggactag tcacgggaca ccgagtccag agtcggcccc agccagtgtg caagccacat
     1861 gtgaggagcg aatagggact gaccagtggg ggaccaggtg accgtcccca tccatttctc
     1921 cttggccgac cacagggcca gctaggatgg caataactat gactttgaat acacatttaa
     1981 aacaaacaca gctaaacacc cacagcctag agcaataaga gcagcttccg ctgccagaga
     2041 agacttggat tttgtgtccg tttttccttt gcaggtagaa atttacctca ttattattat
     2101 tattattttt taaagcaatc aagcttgaaa gttatgaagc ccacagatcc tggcaaatgt
     2161 gcccaaccag ttttattgag tggagaggga aggaggagaa agttgagttt gccagaaaag
     2221 tgcctggttc tgtgtgcata ttcttctgtt gttggaccca cagcagtttt gttctagatc
     2281 cttctaggcc acagtattct ggttagccgt caactggata attgatgttt aatgagtatt
     2341 gagaacctga gcatgtgtgt gtgtgcgtgt gtgtgcagga gtctggtggc tttgggatat
     2401 gtttctgttg aggtcacaca cagagacaca aagctgtgct ggcggtgagg ggagtgtggc
     2461 aggtaggtgg tcgctggggt caccgtcttt catcgttgcc actgagaagc aggcagggtg
     2521 acttgcaagg aacaaggttg gtcacttttt gcagctggct cctgggccca ctgacccagc
     2581 cgggcaagct tttctctcta gtttgactgc gggtagagca tttggcctag gatctggata
     2641 tcgtctgggg aaatgccatc ttttctaagg tgctcctgga aaactgggtg caattcagat
     2701 tttcctaccg tgaatcattt tggtaaggcc agctcagaac cagatcactg aagatgaact
     2761 aaaaatgaat ctcctcttgg cgttgatctc ctccctccct cggataaatt gggcgtttca
     2821 gttctaggag tttacttgaa gtatacatac caagaaattc ttgttacgaa atccctgtca
     2881 agtgaatact ttgaaaagtc ctccctcttt tgagtaaaaa gataagtgta tgtctgactt
     2941 ggggctcctt acggtctgga agggagagag cagagttggg gggctgcgtg ctagctccta
     3001 tcttactgat agtgactcag aagccatgtt gggttctgac tgggccaaca ccattttaaa
     3061 agagcctttc caagtggagg aaaggcattg gagtgtgttt tctaggggga aggtgcaggg
     3121 tggggaggga acctgtttcg tctgtagttt tgggggacag ttttgtgacg gcatgtcaga
     3181 ttagatagag gtcactgcag acctggcaga aatgagcacg gtcccgcccc cctcccccac
     3241 tttgagcata aatataaaac tacaagtgtc cacgttacat catgatggaa tgctttctca
     3301 tccagagtcc cagacagccc gggctcatgg tttttccgtc catgaaaagg ggacttacgt
     3361 tgctatgact tgtattgggt ggcctgtgtc aaaccccacc tttggctgag aagcaagggg
     3421 tgtcctgatt ccctgactgc cgcttggctg aaggcatgga ggggctgagc tcctcgacgc
     3481 tggactgcct atgcctagtt ggatggtcct acgtttgccc cctgcttcct ggcagctgtt
     3541 tcatgtttgg tgaagaatta gatgagatgt gtttttgtag ctaggcaagt cctgggttcc
     3601 cagagtaaag ggtatgtgga gagcaggtat ctgttagact acattcactt tctatatgag
     3661 tgcttgccaa atgtgtccta gttcccagac tggatcccaa ctgcacaggc agtgggagct
     3721 ccaaatgtcc ctcccctgct tcctaattca aacctcctat gacagtgtca aggggctatt
     3781 tataaagtca tgttctttgt acttgataac agcatgagac ccaaaactct tagaaaatag
     3841 gacactggtt tgattgaaaa aaggggaggc acaccttaaa catattctcc agaagcttct
     3901 ctgatggctt ggaatagctc taatgacgac cgtgtcccaa gggtcaagga ccatttcccg
     3961 tccatgagct gatttctggt gatggggagt tttggaaagt cagaaagaaa gccattgagt
     4021 atttgtagta tttgtaggag aatgaggttt tcctccggaa acttggctcc ctccatggtg
     4081 ttcctgggac cctgagggct aaagtacagg tgaggcagtg gctggcagtt ctcagctcca
     4141 ttctcccctg agaccttgtg ctcttgttct tggctttctg taagactggg gaagccaagg
     4201 gaggggtttg agagtccttg agaaggaggc aggaaggagg aagattgata gttactccca
     4261 aggggaaggg actgggtggt ggccaaggaa gcctgtggca gtgataacag tagctcatct
     4321 gggttcataa tcacctgggt agcctttaaa atcctcatat ctaggtgacc cttgaccaaa
     4381 taaaccagga cgtggggggt gggggggtgg gaaaacggga cttagacacc gatctgttac
     4441 agtgttcact gttatgtgct ttgactggag acaccattgc ttggggatgg tgaaagccag
     4501 gtcttgtagg cacagagtag taaacagacg gtacagtagg gctttgtaac agggtcactg
     4561 tggtcccgct ctccacagct ggctgaggga atgctgtggt ttctttgtgg ggagcccgaa
     4621 tgggaaccaa tttgtggagc attgtgagtg ggctcaatat agtgtctggg tgttgatgtg
     4681 tttccttaaa ttttgtctgc aggaaagatg gagaaagtat gtgtctgttt tgaagtcctc
     4741 cttctagtgc cctatccttc cttagaactc acgaatcatt caagggactt cagaaagata
     4801 acaatgcaat acttgtaacg tgtgtaaata gcccccgtct ttctgagtgc tgtcatttct
     4861 acatttgata tgctcgtatt tctgtaggtt gtaccttgtt ttctagaaga gtcaaacatg
     4921 tctgttttta tttattgctt gaaaaaagat catttgaaga aaaataaata cattttcaac
     4981 catt
//
