LOCUS       NM_001012352            1630 bp    mRNA    linear   ROD 17-JUN-2024
DEFINITION  Rattus norvegicus dual specificity phosphatase 26 (Dusp26), mRNA.
ACCESSION   NM_001012352 XM_224932
VERSION     NM_001012352.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1630)
  AUTHORS   Xiang,H., Li,Z., Li,Y., Zheng,J., Dou,M., Xue,W. and Wu,X.
  TITLE     Dual-specificity phosphatase 26 protects against kidney injury
            caused by ischaemia-reperfusion through restraint of
            TAK1-JNK/p38-mediated apoptosis and inflammation of renal tubular
            epithelial cells
  JOURNAL   Toxicol Appl Pharmacol 487, 116954 (2024)
   PUBMED   38705402
  REMARK    GeneRIF: Dual-specificity phosphatase 26 protects against kidney
            injury caused by ischaemia-reperfusion through restraint of
            TAK1-JNK/p38-mediated apoptosis and inflammation of renal tubular
            epithelial cells.
REFERENCE   2  (bases 1 to 1630)
  AUTHORS   Shang,X., Vasudevan,S.A., Yu,Y., Ge,N., Ludwig,A.D., Wesson,C.L.,
            Wang,K., Burlingame,S.M., Zhao,Y.J., Rao,P.H., Lu,X., Russell,H.V.,
            Okcu,M.F., Hicks,M.J., Shohet,J.M., Donehower,L.A., Nuchtern,J.G.
            and Yang,J.
  TITLE     Dual-specificity phosphatase 26 is a novel p53 phosphatase and
            inhibits p53 tumor suppressor functions in human neuroblastoma
  JOURNAL   Oncogene 29 (35), 4938-4946 (2010)
   PUBMED   20562916
REFERENCE   3  (bases 1 to 1630)
  AUTHORS   Tanuma,N., Nomura,M., Ikeda,M., Kasugai,I., Tsubaki,Y.,
            Takagaki,K., Kawamura,T., Yamashita,Y., Sato,I., Sato,M.,
            Katakura,R., Kikuchi,K. and Shima,H.
  TITLE     Protein phosphatase Dusp26 associates with KIF3 motor and promotes
            N-cadherin-mediated cell-cell adhesion
  JOURNAL   Oncogene 28 (5), 752-761 (2009)
   PUBMED   19043453
REFERENCE   4  (bases 1 to 1630)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 1630)
  AUTHORS   Hu,Y. and Mivechi,N.F.
  TITLE     Association and regulation of heat shock transcription factor 4b
            with both extracellular signal-regulated kinase mitogen-activated
            protein kinase and dual-specificity tyrosine phosphatase DUSP26
  JOURNAL   Mol Cell Biol 26 (8), 3282-3294 (2006)
   PUBMED   16581800
REFERENCE   6  (bases 1 to 1630)
  AUTHORS   Vasudevan,S.A., Skoko,J., Wang,K., Burlingame,S.M., Patel,P.N.,
            Lazo,J.S., Nuchtern,J.G. and Yang,J.
  TITLE     MKP-8, a novel MAPK phosphatase that inhibits p38 kinase
  JOURNAL   Biochem Biophys Res Commun 330 (2), 511-518 (2005)
   PUBMED   15796912
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC089954.1.
            
            On Feb 18, 2005 this sequence version replaced XM_224932.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089954.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN12840115
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1630
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.3"
     gene            1..1630
                     /gene="Dusp26"
                     /gene_synonym="RGD1310090"
                     /note="dual specificity phosphatase 26"
                     /db_xref="GeneID:306527"
                     /db_xref="RGD:1310090"
     exon            1..258
                     /gene="Dusp26"
                     /gene_synonym="RGD1310090"
                     /inference="alignment:Splign:2.1.0"
     exon            259..554
                     /gene="Dusp26"
                     /gene_synonym="RGD1310090"
                     /inference="alignment:Splign:2.1.0"
     CDS             334..969
                     /gene="Dusp26"
                     /gene_synonym="RGD1310090"
                     /EC_number="3.1.3.16"
                     /EC_number="3.1.3.48"
                     /note="dual specificity phosphatase 26 (putative)"
                     /codon_start=1
                     /product="dual specificity protein phosphatase 26"
                     /protein_id="NP_001012352.1"
                     /db_xref="GeneID:306527"
                     /db_xref="RGD:1310090"
                     /translation="MCPGNWLWASMTFMARFSRSSSRSPVRTRGSLEEMPSVHHPFLN
                     VFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGT
                     PEAYEGLGIRYLGVEAHDSPAFDMSVHFQTAADFIHRALSQPGGKILVHCAVGVSRSA
                     TLVLAYLMLYHHFTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLRQGLEA"
     exon            555..769
                     /gene="Dusp26"
                     /gene_synonym="RGD1310090"
                     /inference="alignment:Splign:2.1.0"
     exon            770..1604
                     /gene="Dusp26"
                     /gene_synonym="RGD1310090"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggggctgta aacaggggcg ggctgtgtcg ctgcggtgtg gcggctccca ccgctgcgtg
       61 acacggtgtc cctggatgtc accagcgcgc acaccgaaag gaacctgctt cgatgtacgt
      121 gtcatggctt aaaaatagct gggatccacc tgcgcgccgg ggcggcggcg cagcggcggg
      181 ggccgtgaag gagccatggg caccggactg cgggagcccg caggccaact cgggatctga
      241 gacccttgcg accaggagca acagccacct ggtgacaaag cccatcactg ctgaaaccac
      301 tccgcgttgg ccgcagatcc cgccaccttg aagatgtgcc ccggtaactg gctgtgggct
      361 tccatgactt ttatggcccg cttctcccga agcagctcaa ggtcccctgt tcgtacccga
      421 gggagcctgg aggagatgcc cagtgttcac catcccttcc tcaatgtctt tgagttggaa
      481 aggctcctct acacgggcaa gacagcctgc aaccatgctg acgaggtctg gccaggcctc
      541 tacctcggag accaggacat ggccaacaac cgccgtgagc ttcgtcgcct gggcatcacc
      601 cacgtcctca acgcctccca cagcaggtgg cgaggcaccc ccgaggccta cgagggactg
      661 ggcatccgct acctgggtgt tgaagcccac gactcgccag cctttgacat gagcgtccac
      721 tttcaaaccg ctgcggactt tatccatcgg gcactgagcc agccaggagg gaagatcctg
      781 gtgcactgtg cggtgggagt gagcagatct gccaccctgg tgctggccta cctcatgctg
      841 taccaccact tcaccctcgt ggaggccatc aagaaagtca aggaccaccg aggcatcatc
      901 cccaacaggg gcttcttgag acagctccta gccctggacc gtaggctgcg tcagggtcta
      961 gaagcatgag ctgaagggga tcaggccagg tccctgagtg gtttcctgac tcccagctgg
     1021 gaagagaaaa cctgggaggc aggtagtaga aaggccatac cacccatcct cccccagtgg
     1081 caggagagtg aagagtccca agaccgctgt ggctctttgt ggatggggat ggagggccag
     1141 gttgggcaat gtggtcggtg ggggctgctg accaggaagc agtggggctc taagtagagg
     1201 atggctcgat gattaggata tccccgcgtt ccagcagggt acgcccaaat gactcagaat
     1261 ctcttcccct cattgtgttc aagtgtcccc ctctctcgct tttccaaaca aaacgaccac
     1321 tgccctgaag tacctgagca gtggggatgt cagggaccca gcaacacgga tgtgaaggaa
     1381 gattgtacag gttgcagaaa acaacacagt cagttggtga tggtgtggtg tgaaagttac
     1441 caatccagag ggagaaacct acccccctgt gcaactgcag gaagaggagg tgtgtgacag
     1501 gacaccctac cggagctgct tggggtctaa tgacttggag tctttaggtg gtcatattct
     1561 cactgaaaac catgcgtctg gagtaaaaat aaagaagtga aaaaaaaaaa aaaaaaaaaa
     1621 aaaaaaaaaa
//
