LOCUS       NM_001401393            5562 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus deltex E3 ubiquitin ligase 4 (Dtx4), transcript
            variant 1, mRNA.
ACCESSION   NM_001401393 XM_039108698
VERSION     NM_001401393.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5562)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 10, 2022 this sequence version replaced XM_039108698.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582424.2248695.1,
                                           SRR26643429.5129.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760494 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-812               JAXUCZ010000001.1  218916319-218917130 c
            813-1536            JAXUCZ010000001.1  218907383-218908106 c
            1537-1598           JAXUCZ010000001.1  218901989-218902050 c
            1599-1760           JAXUCZ010000001.1  218900809-218900970 c
            1761-1822           JAXUCZ010000001.1  218898669-218898730 c
            1823-1975           JAXUCZ010000001.1  218897695-218897847 c
            1976-2137           JAXUCZ010000001.1  218893755-218893916 c
            2138-2227           JAXUCZ010000001.1  218889024-218889113 c
            2228-5562           JAXUCZ010000001.1  218882391-218885725 c
FEATURES             Location/Qualifiers
     source          1..5562
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..5562
                     /gene="Dtx4"
                     /gene_synonym="LRRGT00037"
                     /note="deltex E3 ubiquitin ligase 4"
                     /db_xref="GeneID:293774"
                     /db_xref="RGD:1311767"
     exon            1..812
                     /gene="Dtx4"
                     /gene_synonym="LRRGT00037"
                     /inference="alignment:Splign:2.1.0"
     CDS             602..2461
                     /gene="Dtx4"
                     /gene_synonym="LRRGT00037"
                     /EC_number="2.3.2.27"
                     /note="isoform 1 is encoded by transcript variant 1;
                     deltex 4 homolog; protein deltex-4; deltex homolog 4; E3
                     ubiquitin-protein ligase DTX4; deltex 4, E3 ubiquitin
                     ligase"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase DTX4 isoform 1"
                     /protein_id="NP_001388322.1"
                     /db_xref="GeneID:293774"
                     /db_xref="RGD:1311767"
                     /translation="MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRAGGSV
                     VLGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGSW
                     TPYDMEVGITIQHAYEKQHPWIDLTSIGFSYIIDFSTMGQINRQTQRQRRVRRRLDLI
                     YPMVTGTVPKAQSWPVSPGPATPSPAPPCSCPQCVLVMSVKAAVVHGSTGPLHPPAAR
                     KNIAPSGVGKLPQPPGPGAKPLDTTGTIRGPGKTAPSQVIRRQVSNTPAGVTVGSPAS
                     PQGSNRKTGRVALTTLNRSNLQRLAIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGI
                     TGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKTPEE
                     VLKKYLQKVRHPPEEDCTICMERLTAPSGYKGPQPTVKPDLVGKLSKCGHIYHIYCLV
                     AMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYSIP
                     PGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTG
                     ESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTSQEKD"
     exon            813..1536
                     /gene="Dtx4"
                     /gene_synonym="LRRGT00037"
                     /inference="alignment:Splign:2.1.0"
     exon            1537..1598
                     /gene="Dtx4"
                     /gene_synonym="LRRGT00037"
                     /inference="alignment:Splign:2.1.0"
     exon            1599..1760
                     /gene="Dtx4"
                     /gene_synonym="LRRGT00037"
                     /inference="alignment:Splign:2.1.0"
     exon            1761..1822
                     /gene="Dtx4"
                     /gene_synonym="LRRGT00037"
                     /inference="alignment:Splign:2.1.0"
     exon            1823..1975
                     /gene="Dtx4"
                     /gene_synonym="LRRGT00037"
                     /inference="alignment:Splign:2.1.0"
     exon            1976..2137
                     /gene="Dtx4"
                     /gene_synonym="LRRGT00037"
                     /inference="alignment:Splign:2.1.0"
     exon            2138..2227
                     /gene="Dtx4"
                     /gene_synonym="LRRGT00037"
                     /inference="alignment:Splign:2.1.0"
     exon            2228..5562
                     /gene="Dtx4"
                     /gene_synonym="LRRGT00037"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttggcctct ggggccggga tggcgcgtgt gctcccggca ccgggggacc agggacgctt
       61 cctcgggtgc gagttcgcct tggcgctctg cccgggaggg gcgactcctt cttgcagcca
      121 ctgagcggag ccgcagggag ggggagctgt gccaccgcgg tcgccttgct ccgtacggag
      181 agagggcgga gggcgtgacc gtgcggcgcg atccacgcgg gcacccgcgg agcccgaggc
      241 gcaactagtg cgaggagggt gcaacgttgc gctcgggccg cgcacccccg ggtggctttg
      301 caaggcgggg cggcgagtgc gcagggccgg gcctttgcat gaagcctctg gacccctcgg
      361 agcagcggca gcggcggcgg cggagcccgg cggagcgcag tccgaagcgg gcggccccgg
      421 ggtccgcgtc ctggtgccta cgcggctgcg gactccccca tgggctgctg ctgaggcttc
      481 ccgcagcgga ggggcgcggg ccggggggcg cggttgagac ccggaggcgg cggcgccgga
      541 ggaagcgcag aaggccgggc ccgggaggcg gccagcacct cgccgcagcc ccgggctcgc
      601 catgctcctg gcctcggccg tggtggtgtg ggaatggctg aacgagcacg gccgctggcg
      661 tccctacagt ccagccgtga gccaccacat cgaggcggtg gtgcgcgctg gtccccgcgc
      721 cgggggcagc gtggtgctgg gccaggtgga cagccggctc gcaccctaca tcatcgacct
      781 gcagtccatg aaccagttcc gccaagacac ggggaccctc cgtccagttc gcagaaacta
      841 ctacgaccca tcctcggccc ctgggaaggg tgtggtgtgg gagtgggaga atgacaatgg
      901 ttcctggacg ccctatgaca tggaagtcgg catcaccatc cagcatgcct atgagaagca
      961 gcacccatgg atagacctca cttccattgg cttcagctac ataatagact tcagcaccat
     1021 gggccagatc aacaggcaga cccaacgcca acgccgtgtc cgccgccgac tagacctcat
     1081 ctaccccatg gtcacgggca ctgtaccaaa ggctcagtcc tggccagtca gcccagggcc
     1141 ggccacgccc tcccctgcac caccttgctc ctgtccacag tgtgttttgg tgatgagtgt
     1201 caaggctgct gttgtccatg ggagcacggg gccccttcac cctccagcag cgcgaaaaaa
     1261 catcgccccc tctggagtgg gcaagctgcc ccagccacct ggccctgggg caaagccact
     1321 agacaccact ggcaccatcc ggggcccagg gaagactgcc ccatcccagg tgatccggag
     1381 acaagtctct aacacgccag ctggggtgac tgtaggctcc cccgccagcc cacagggaag
     1441 caaccggaag actggaaggg tggccctgac cacgttgaat cggtccaatc tgcagcgact
     1501 ggccattgcc cagtcccggg tgctgattgc ctcgggggtt cccactgtgc ctgtgaaaaa
     1561 cttgaatggg tccagccctg ttaatcctgc cttggcagga atcaccggga tcctcatgag
     1621 tgcagcggga ttgcctgtgt gtctcactcg tccaccaaag ttggtcctcc acccgccccc
     1681 tgtcagcaag agtgagataa agtccatccc aggggtctct aacacaagcc gcaagaccac
     1741 caaaaaacag gctaagaaag gtaaaacccc agaggaagtg ctaaagaagt atctgcagaa
     1801 ggtccggcac ccaccagaag aggattgtac catctgtatg gagcgcctca cagccccctc
     1861 tggctacaag ggcccacagc ccacagtcaa gcctgacctg gtaggaaagc tgtcgaagtg
     1921 tggccacatc taccacatct actgcctggt ggccatgtac aacaatggga acaaggatgg
     1981 aagtttacag tgcccaacat gtaagaccat ttatggcgtg aagacaggca cccagcctcc
     2041 agggaagatg gagtaccacc tcatccccca ctccttgcct ggccatccgg attgcaagac
     2101 cattcggatt atctacagta tcccccctgg cattcaggga ccagaacatc cgaatcctgg
     2161 gaagagcttc agcgcccgtg gcttcccacg acattgttac cttccagaca gcgagaaagg
     2221 gagaaaagtt ctgaagctgc ttctagtggc ctgggaccgc cgtctcatct ttgccattgg
     2281 aacctccagc accacgggcg agtctgatac tgtcatctgg aatgaggtgc accacaagac
     2341 agaatttggc tctaatctca ctggccatgg ctacccagat gccaattacc tggataacgt
     2401 gctggctgaa ctggctgccc agggtatctc tgaagacagc acttcccagg aaaaagactg
     2461 aggagggagg gtactgggga ccccagggca ggaaatggag agtcaaggtg gaggttgatg
     2521 ccatgcctcc tgactccctc attccccttc ttgtattatc cccacctctc atctctctca
     2581 gtcacagagg gagctagatt aaggtgatat cattcataaa cttcatctaa tgcaaacaag
     2641 atgtggggtg aggaccaacc tctttctgtc cccatggagt ctccagtact ggttaggcaa
     2701 gaacatgcac ctctccccac cctaagcagg ggttacagtc agcacactta acgtagttaa
     2761 ggtagtgttg aggcactcca tgtcctggcc ttgtgaagct gagatccctt gcctcagctg
     2821 gcttcttgct gcttcagctc tgtgttgagg gttgagtttc tgcttctttt tctcctacac
     2881 tggagtgagg gagctctcac tgtgcgagat tggggagagg ggtgtaaact gctgtgacat
     2941 cagaaattgg atgctttggt gcagagtaag gaagccgttc atgttaagag ggtcagagtc
     3001 aaatgcctct gggagcatgt ctctagtgag gagtctgggc cctcccttcc tcctcattcc
     3061 attgacctgt ccataggtat ctgattctct caagtggatg gaaggactca gggattcctc
     3121 tctggggagg catcccatga tgctgtttcc aaccaactgc tctctgatcc aatgagagcc
     3181 tgcatctcac caagcatctg cactatcctc agggagagga gcccatagcc tccttcccaa
     3241 ctcatttcaa accagctcag tttcatcaag tcactgtgag ttggagccca cagcaggctc
     3301 tttgccatct gtgtatgtgc atatgtttgt gtgggtgtat gtgcgttact gggccaggtt
     3361 attgggacag tcatcatttc tctgaattct gtttcacaag ccaaatctca attccgttgg
     3421 ggatcccata gtaaaggtgt ggccctttga cttctctcac cctttcccag cccatctcat
     3481 gataaacttg gaccttgatg gacacagaat tgtacttggg aagatgtgtt gatgcaagag
     3541 ctaagatgga tccttctctt attaatatta gatcagagcc agcttccatt cagtcttgtt
     3601 tgtatgagtg ctcaattcat ctccctgaag attgctaatt caaggccaga gatattgcta
     3661 ttccccatcc gagccccttt ctccagtctc catttagtat agattggcca aaaccatggt
     3721 gacagaagcc tctttagttc attcctaaca tagttaggaa cacattctga tcttctctaa
     3781 acaccatctg ggtggtgtcc caagatccaa tctatcacca acatttcctc aactttggct
     3841 ccattaaaga atggattagg tgtcaagtaa gagagaatga agagtcaaga agggaaacca
     3901 atttcccctt tggaagtggg ttctttgaac tctgtgtttg gagaaagttc ctctggatac
     3961 taatttgaac taatatacct catgtcttga ggatttaact atatttcata agatttgaaa
     4021 ggtttttata gcttgagggg caaaaagaga aattaaacaa cctccacaat ggtaattaag
     4081 ttaggactga agtccacact ttcatgccac cctgcaccag agatgcctcc tgttgggctt
     4141 ccactattgt tgacattgct gtggccagta gaatcaccca agtgtcccta accaagttcc
     4201 ctggtgctga gttttctttt cactctacaa atgactaatg gaattttgat ttcctccctc
     4261 tagggggagc tgtggtagga gcaaatgttc tgccatttta gtccaacctg tcctatcaat
     4321 gggaggccat tttgtctcac tagcagaaca aaagattgct gagttcactg aacctcgggg
     4381 aaaactcccg ccaaagtaga gaaagacgca tcagaactaa gtggagggca catatccttg
     4441 ggggttaaag ccacaccctt tcatcaggtt actgcatttc attgagggct tacaatcact
     4501 tttgccttca gtaccctttg ttacctacct tccctgcttc ttggcgacag ggatgagaaa
     4561 tccagactgg gagtcgaggg ataggaaagt gaagcaatgt aaagcaaaga aatgaaaata
     4621 ggctctgagg tgtgggaata gacagcgggg aatgttttca taagctgagg aagcagatgc
     4681 aggaaaagtg ttgcacaagg cagaagacaa acccagaagg acatctcagg gagatgttct
     4741 agaagaaaaa ccattttaag ggttagtttt cacgccttca agaatttccc ccagaggaca
     4801 tttaaaatgt ctatgcctcg tttccttctt cgctgaggat gctgtgaccc tcaagtcaca
     4861 ttctttcaac tttctggtct aatggaacct tgacaatctc aacagtgtgt cagtcaaagt
     4921 ggtggccggt accttactct ttctcttgtg acaacccaaa tatgtgcaga attgatttca
     4981 gtgacattag gccctgggca ccagctactt tgaccctgag tgttttccca agagaagccc
     5041 tgtgtgttct actgggccaa gcaggagtcc catgcttttt ctttcatggt ctcagtacca
     5101 gcagccatgt tctctctccg tgagactcca ggggtgacaa atgggattgg agacacacct
     5161 tgtgagatgc ttatcccttg aaaagctctg tagtatgtct gtggttgtct gtgcctttgt
     5221 gcttccgttc ccctctcctt tttgtaagat tcagacttct gtgtgctttt atacttgggt
     5281 caaaagtact tgtcctggta tcgcactgtt gtgtgcatga gaagattggg aaaaggctgc
     5341 tgtggcccaa gaaataacca ctgcccccct ttgtttgttg gcgttcactt atatctcatt
     5401 gggagtttct gggagagggc tggtgaatgt ccagatgtca ggtgttctgt ttgtaagtgc
     5461 tgtgatttga agttgttggt gtcgttctgt gggaggacat cgccccctgg tgctcatgag
     5521 gtgtatgtgc agaacaataa acggcaaatg aataagcaca aa
//
