LOCUS       NM_001191989            1558 bp    mRNA    linear   ROD 07-MAY-2024
DEFINITION  Rattus norvegicus deltex E3 ubiquitin ligase 3 (Dtx3), mRNA.
ACCESSION   NM_001191989 XM_576239
VERSION     NM_001191989.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1558)
  AUTHORS   Kishi,N., Tang,Z., Maeda,Y., Hirai,A., Mo,R., Ito,M., Suzuki,S.,
            Nakao,K., Kinoshita,T., Kadesch,T., Hui,C., Artavanis-Tsakonas,S.,
            Okano,H. and Matsuno,K.
  TITLE     Murine homologs of deltex define a novel gene family involved in
            vertebrate Notch signaling and neurogenesis
  JOURNAL   Int J Dev Neurosci 19 (1), 21-35 (2001)
   PUBMED   11226752
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Jul 17, 2010 this sequence version replaced XM_576239.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.39374.1,
                                           SRR26643297.25403.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                JAXUCZ010000007.1  64903732-64903752   c
            22-240              JAXUCZ010000007.1  64902464-64902682   c
            241-314             JAXUCZ010000007.1  64902219-64902292   c
            315-1063            JAXUCZ010000007.1  64901116-64901864   c
            1064-1281           JAXUCZ010000007.1  64899680-64899897   c
            1282-1558           JAXUCZ010000007.1  64899091-64899367   c
FEATURES             Location/Qualifiers
     source          1..1558
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..1558
                     /gene="Dtx3"
                     /gene_synonym="RGD1566181"
                     /note="deltex E3 ubiquitin ligase 3"
                     /db_xref="GeneID:500847"
                     /db_xref="RGD:1566181"
     exon            1..21
                     /gene="Dtx3"
                     /gene_synonym="RGD1566181"
                     /inference="alignment:Splign:2.1.0"
     exon            22..240
                     /gene="Dtx3"
                     /gene_synonym="RGD1566181"
                     /inference="alignment:Splign:2.1.0"
     exon            241..314
                     /gene="Dtx3"
                     /gene_synonym="RGD1566181"
                     /inference="alignment:Splign:2.1.0"
     CDS             314..1357
                     /gene="Dtx3"
                     /gene_synonym="RGD1566181"
                     /EC_number="2.3.2.27"
                     /note="deltex 3 homolog; protein deltex-3; deltex homolog
                     3; deltex 3, E3 ubiquitin ligase"
                     /codon_start=1
                     /product="probable E3 ubiquitin-protein ligase DTX3"
                     /protein_id="NP_001178918.1"
                     /db_xref="GeneID:500847"
                     /db_xref="RGD:1566181"
                     /translation="MSFVLSRMAACGGSCKNKVTVSKPVWDFLSKETPARLARLREEH
                     RVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKAQRQGEL
                     MGCLALGGGGEHPELHRPGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREDAEEQ
                     ETTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGR
                     MLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGN
                     KVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTR
                     VQEELRAKGITDD"
     exon            315..1063
                     /gene="Dtx3"
                     /gene_synonym="RGD1566181"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1281
                     /gene="Dtx3"
                     /gene_synonym="RGD1566181"
                     /inference="alignment:Splign:2.1.0"
     exon            1282..1558
                     /gene="Dtx3"
                     /gene_synonym="RGD1566181"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caatggcggc gctgacgaga ggatctccct ctgcactggg agaaaaagag aagttagcct
       61 gatgaagttc cttgagcaac ttggagagga tcctgcagga gagaggaaat agaggagcgt
      121 tttctttctg ggctggctga ggaaatgcta tcataactct ttaccttcct cgtccccagc
      181 tctggccagc tgaaggtgga ggtggaggga tccgctacca ccataccgtg gtcttttcag
      241 gccacacgat ctccaagtag caagggggaa agagagtgag cctgcatgcc aattctaagc
      301 tcttccggat caaatgtcgt tcgtcctgtc cagaatggca gcctgtggag gctcctgcaa
      361 gaacaaagtg acagtctcca agcctgtgtg ggacttcctg agcaaggaga ccccagcccg
      421 gctggcccgg cttcgggagg agcaccgagt gtccatcctc atagatggcg agacttctga
      481 catctatgtg ctccagctgt ctccacaggg tcctcccccg gcccccccca atgggctcta
      541 cctggccagg aaggctctca aggggctact gaaagaggca gaaaaagagc tgaagaaagc
      601 tcagaggcag ggggagctca tgggctgcct ggctttgggg ggtggagggg agcaccctga
      661 gctgcaccgc ccaggcccac ctcctctccg agcagcccca ctcctgcccc caggggcaag
      721 agggctcccc cctcctcctc ctcccctgcc ccctccactc cctcctcgtc tcagagagga
      781 tgctgaagag caggaaacca cctgccccat ttgcctgggg gagatacaga atgccaagac
      841 gctggagaag tgcaggcact ccttctgtga gggctgcatc acaagggccc tgcaggtgaa
      901 aaaggcctgc cccatgtgcg gccgattcta cgggcagctg gtgggcaacc agccccagaa
      961 tgggaggatg ctggtttcca aggacgccac cctcctgttg cccagctatg agaagtacgg
     1021 caccattgtc atccaatatg tcttcccgcc tggcgtccag ggggctgaac accccaaccc
     1081 aggagttcgg taccctggta ccacacgggt ggcctacctc ccggactgcc ccgagggcaa
     1141 caaggtgctg accctgttcc gaaaggcatt tgaccagcgt ctcaccttca ctatcggcac
     1201 gtccatgact acagggagac ccaatgtcat cacttggaac gacatccacc acaagaccag
     1261 ctgcacaggg ggaccccagc tgtttgggta tccggaccca acctacctga ctagggtgca
     1321 agaggaactg agagccaagg gtattacaga cgactgaagt atggctcctt tgccaaggcc
     1381 cccccccgct gtcctctact aggatccaac ggaagcctct gctcctctct tgctgccccc
     1441 acatcaccca tgaggggata tgtctgactg ggatgggagc ccagagggga aggggatgtt
     1501 ccttcccctg cccgccactg gccaagtgct tcagtgccct ttgagccact cccctcta
//
