LOCUS       NM_001393773            1445 bp    mRNA    linear   ROD 03-MAY-2024
DEFINITION  Rattus norvegicus DTW domain containing 1 (Dtwd1), transcript
            variant 2, mRNA.
ACCESSION   NM_001393773 XM_006234910
VERSION     NM_001393773.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1445)
  AUTHORS   Takakura,M., Ishiguro,K., Akichika,S., Miyauchi,K. and Suzuki,T.
  TITLE     Biogenesis and functions of aminocarboxypropyluridine in tRNA
  JOURNAL   Nat Commun 10 (1), 5542 (2019)
   PUBMED   31804502
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Mar 10, 2021 this sequence version replaced XM_006234910.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582424.67221.1,
                                           SRR22582419.201525.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-163               JAXUCZ010000003.1  133845870-133846032
            164-479             JAXUCZ010000003.1  133848654-133848969
            480-623             JAXUCZ010000003.1  133852656-133852799
            624-882             JAXUCZ010000003.1  133854146-133854404
            883-1445            JAXUCZ010000003.1  133859403-133859965
FEATURES             Location/Qualifiers
     source          1..1445
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..1445
                     /gene="Dtwd1"
                     /gene_synonym="RGD1311144"
                     /note="DTW domain containing 1"
                     /db_xref="GeneID:296119"
                     /db_xref="RGD:1311144"
     exon            1..163
                     /gene="Dtwd1"
                     /gene_synonym="RGD1311144"
                     /inference="alignment:Splign:2.1.0"
     exon            164..479
                     /gene="Dtwd1"
                     /gene_synonym="RGD1311144"
                     /inference="alignment:Splign:2.1.0"
     CDS             216..1130
                     /gene="Dtwd1"
                     /gene_synonym="RGD1311144"
                     /EC_number="2.5.1.25"
                     /note="isoform 1 is encoded by transcript variant 2; DTW
                     domain-containing protein 1; tRNA-uridine
                     aminocarboxypropyltransferase 1"
                     /codon_start=1
                     /product="tRNA-uridine aminocarboxypropyltransferase 1
                     isoform 1"
                     /protein_id="NP_001380702.1"
                     /db_xref="GeneID:296119"
                     /db_xref="RGD:1311144"
                     /translation="MALSPSVVPQESEENNANCVETKQSQTASTASEDPLQHLCLASQ
                     EVLHKAQQSGRSRCLQCGGSRMFYCYTCYVPVENVPTEQIPFVQLPLKIDIIKHPNET
                     DGKSTAVHAKLLAPDSVNIYTYPCIPEYEGQDHEVVLVFPGPQSISIKDVSFHLQKRI
                     ESKSGDKADDLDMPPRKLVRTEAQEGWHLNESMGKGPELKRVVFIDSTWSQTNQITSD
                     ERLRELLQVELKTRKTCFWRHQKGKPDTFLSTIEAIYYFLVDYHRAVQKEEYRGQYDN
                     LLFFYSFMYRLIKEARRSGEKAKQKPIH"
     exon            480..623
                     /gene="Dtwd1"
                     /gene_synonym="RGD1311144"
                     /inference="alignment:Splign:2.1.0"
     exon            624..882
                     /gene="Dtwd1"
                     /gene_synonym="RGD1311144"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1445
                     /gene="Dtwd1"
                     /gene_synonym="RGD1311144"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggggcgcgt ggagcggagg ccgtacggac cgagagttcg tcgtggtgca ggttggcctt
       61 ccctcaagtc cggtagctgg ggccagacac cggacaggcc cagcgaaggt cttactgcgg
      121 gcgaacgctg cgtgtggcgt tcctgtgggg aaagactcga aagtgtacct atgatacacg
      181 ctttagaaac agaatacttt ggttcaaaga aaaaaatggc tctcagtcca tctgtagttc
      241 ctcaagaaag tgaagaaaac aatgcaaact gtgtagaaac gaaacagtca caaactgctt
      301 ccactgcatc agaggacccc cttcaacact tatgcttagc gtctcaggag gtgcttcata
      361 aggctcagca aagtgggagg tcacggtgtc ttcaatgtgg tggctcaagg atgttctact
      421 gctacacatg ctatgtcccg gtggaaaatg tgcccactga gcagatcccg tttgtgcagc
      481 ttccactgaa gattgatatc attaagcatc cgaatgaaac agacggcaaa agcacggctg
      541 tgcacgcaaa gctcttggcg ccggactctg tgaacattta cacatatccc tgcattccgg
      601 agtatgaagg gcaggaccac gaggttgtac ttgtttttcc tggacctcag tctatctcaa
      661 taaaagatgt ctctttccat ctacaaaaac ggatcgaaag taaaagtgga gacaaagctg
      721 acgacctgga tatgccacct cgtaagctcg tgaggactga ggcacaggaa ggctggcatt
      781 tgaatgagag catgggcaaa ggcccagagc tgaaaagagt tgtctttatt gacagcacct
      841 ggagccagac aaaccagatc acctctgatg agcggcttcg ggagttatta caagttgaac
      901 tgaaaacaag aaaaacttgc ttttggcgcc atcaaaaagg gaagccagat actttccttt
      961 ccacaattga agccatttat tacttcctgg tggactacca tagagccgtg cagaaggagg
     1021 agtacagagg acaatatgac aaccttttgt tcttctactc ctttatgtac cgcttgataa
     1081 aggaggccag acgctctgga gagaaggcca aacagaagcc catccattag ttctgcaagc
     1141 cctcttgacc tgtgctctgc agtgctcgct agcgtgcagc caagccttgt ttcccctggg
     1201 gtaataacca tgcgtgatgc ccatgagagg accccgggga gagtccagcc ttgttcattt
     1261 tattgtattt ttttaatggg aaatttgaat tttggcattt ttaagagatg atcctgatag
     1321 agagacagat cagaagctat ttgctcattt tgggcatatc tcattatatg aggcatttaa
     1381 tatgctgtgc tacatttatg tgatgtaatt atatgtgatt aaagagtgtc atatcttttc
     1441 actta
//
