LOCUS       XM_008766967           17049 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus dystonin (Dst), transcript variant
            X17, mRNA.
ACCESSION   XM_008766967
VERSION     XM_008766967.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051344.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008766967.4.
            
            On Jan 21, 2021 this sequence version replaced XM_008766967.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17049
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..17049
                     /gene="Dst"
                     /note="dystonin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 45 ESTs, 7 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 121 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:316313"
                     /db_xref="RGD:1306566"
     CDS             1..17049
                     /gene="Dst"
                     /codon_start=1
                     /product="dystonin isoform X17"
                     /protein_id="XP_008765189.1"
                     /db_xref="GeneID:316313"
                     /db_xref="RGD:1306566"
                     /translation="MIAAAFLVLLRPYSIQCALFLLLLLLGTIATIIFFCCWHRKLQK
                     GRHPMKSVFSGRSRSRDAALRSHHFRSEGFRASPRHIRRRVAAAAAARLEEVKPVVEV
                     HHQSEQESSGRKRRIKKISRVQPEFYHSVQGASTRRPSSGNASYRCSMSSSADFSDED
                     DFSQKSGSASPAPGDTLPWNLPKHERSKRKIQGGSVLDPAERAVLRIADERDKVQKKT
                     FTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHRLQNVQI
                     ALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKER
                     LLLWTQQATEGYAGVRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEH
                     AFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPKVPEGGEGIGANDVEVK
                     WIEYQNMVNYLIQWIRHHVVTMSERTFPNNPLELKALYNQYLQFKEKEIPPKETEKSK
                     IKRLYKLLEIWIEFGRIKLLQGYHPNDIEKEWGKLIIAMLEREKALRPEVERLDMLQQ
                     IATRVQRDSVSCEDKLMLARNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHVI
                     DVQILLDGKYYQAEQLVQRVAKLRDEILALRNECSAVYSKGRMLTTEQTKLMISGITQ
                     SLNSGFAQTLHPSLNSGLTQSLTPSLTSSSVTSGLSSGMTSRLTPSVTPAYTPGFPSV
                     VAPNFSVGVEPNSLQTLKLMQIRKPLLKSSLLDQNLTEEEVNMKFVQDLLNWVDEMQV
                     QLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAKISEIQMTAPLKLSYTDKLH
                     RLESQYAKLLNTSRNQERHLDTLHNFVTRATNELIWLNEKEESEVAYDWSERNSNVAR
                     KKGYHAELMRELEQKEESIKAVQEIAEQLLLESHPARLTIEAYKAAMQTQWSWILQLC
                     QCVEQHIQENTAYFEFFNDAKEATDYLRNLKDAIQRKYVCDRSSSIRKLEDLVQESME
                     EKEELLQYRSVVAGLMGRAKTVVQLKPRNPDNPLKTSIPIKAICDYRQIEITIYKDDE
                     CVLANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDFANRIEQQYQSVLTLWHE
                     SHVNMKSIVSWHYLVNEIDRIRASNVASIKTMLPGEHQQVLSNLQSRLEDFLEDSQES
                     QIFSGSDITQLEKEVNVCRKYYQELLKSAEREEQEESVYNLYVSEVRNIRLRLESCED
                     RLIRQIRTPLERDDLHESMLRITEQEKLKKELERLKDDLEAITNKCEEFFSQAADSPS
                     VPALRSELSVVLQSMSQIYSMSATYVEKLKTVNLVLKNTQAAEALVKLYETKLCEEEA
                     VIADKNNIENLMSTLKQWRSEVDEKREVFHALEDELQKAKAISDEMFKTHKERDLDFD
                     WHKEKADQLVERWQSVHVQIDNRLRDLEGIGKSLKHYRDSYHPLDDWIQQIETTQRKI
                     QENQPENSKALAVQLNQQKMLVSEIEVKQSKMDECQKYSEQYSAAVKDYELQTMTYRA
                     MVDSQQKSPMKRRRIQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEEE
                     KSLDEEKKQHVEKAKELQKWVSNISETLGDGERAGKPHFSKQQISSKEISAKKEQFSE
                     ALQNTQIFLAKHGDKLTEEDRSDLEKQVKTLQEGYNLLFSESLKQQELQPSGEAKVKV
                     EEKVVAERQQEYKEKLQGLCDLLTQTENRLISHQETFVIGDGTVELKKYQSKQEELQR
                     DMQGSTQALAEIVRNTEIFLKESGDELSQEDKALIEQKLNEAKVKCEQLNLKAEQSTK
                     ELDKVVTAALKEETEKVAAARQLEESKTKIENLLNWLSNVEKDSEGSGRLHTQPLEQN
                     GTHLHEGDGTSEAGEEDEVNGNLLETDAEGHGGMTEGNLNQQYEKVKAQHEKIVAQHQ
                     AVIMATQSAQALLEKQGHHLSPEEKEKLQANVQELKAHYETVLAECEKKVKLTHSLQE
                     ELEKFDADCGEFEHWLQQSEQELENLEAGADDLSGLTDKLARQKSFSEDVISHKGDLR
                     YITISGNRVMEAAKSCSKRDGDRIGKDSLETSATHREVQTKLDQVTDRFRCLYSKCSV
                     LGNNLKDLVDKYQHYEDASCGLLSGLQACEAKASRHLLEPIALDPKNLQRQLEETKAL
                     QGQISSQQAAVEKLKKTAEVLLDAKGSLLPAKNDIQKTLDDIVGRYDDLSKSVNERNE
                     KLQITLTRSLSVQDGLDEMLDWMGSVESSLVKQGQVPLNSTALQDLISKNIMLDQDIT
                     GRQSSINAMNEKVKTFIETTDPSTASSLQAKMKDLSARFSEASQKHKEKLAKMVELKS
                     KVEEFEKLSDKLQTFLETQSQALTEVDMPGKDVPELSQHMQESTTKFLEHRKDLEALH
                     SLLKEISSHGLPGDKALVFEKTNNLSKKFKELEDTIQEKKEALSSCQEQLSAFHDLAQ
                     SLKTWIKETTKQVPIVKPSFGTEDLEKSLEETKKLQEKWSLKTPEIHKANNSGVSLCN
                     LLSALISPAKAIAAARSGGVILNGEGTDTNTQDFLANKGLTSIKTDMTDISHSYEDLG
                     LLLKDKIVELNTKLSKLQKAQEESSAMMQWLQKMNKTASRWRQTPTPADSESVKIQVE
                     QNKSFEAELKQNVNKVQELKDKLAELLKENPEAPEAPSWKQTMAEMDTKWQELNQLTI
                     DRQQKLEESSNNLSQFQTTEAQLKQWLVEKELMVSVLGPLSTDPNMLNTQKQQAQILL
                     QEFDTRKPQYEQLTAAGQGILSRPGEDPSLHGIVKEQLAAVTQKWDNLTGQLRDRCDW
                     IDQAIVKSTQYQSLLRSLSGTLTELDEKLSSSLISGTLPDAVNQQLEAAQKLKQEIEQ
                     QTPKIKEAQTLCEDLSALVKEEYLRAELSRQLEGVLKSFKDIEQKTENHVQHLQSACA
                     SSHQFQQMSKDFQAWLDAKKEEQRNSPPISAKLDVLESLLKAQKDFGKTFTEQSNIYE
                     KTVAEGENLLSKTQGAEKAALQLQLNTIKTDWDRFRKQVKEREEKLKESLEKALRYRE
                     QVDTLQPWVDKCQHSLESVKLSLDPADTERSITELKTLQKEMDHHFGTLELLNNSANS
                     LLSVCEVDKEVVTEGNKSLIQKVNVVTEQLQSKKVSLENMAQKFKEFQEVSKDAKRQL
                     QDTKEQLEVYQSLGPQACSNKHLTMLQAQQKSLQTLKHQVDSARRLAQDLVMEATDPK
                     GTSDVLSQAETLAEEHRGLSQQVDEKCSFLETKLQGLGHFQNTIREMFSQFTEFDDEL
                     DSMAPVGRDVETLQKQKASMQTFLKKLEALITSNDSANRTCKMMLATEETSPDLIGVK
                     RDLEALSKQCNKLLDRAKTREEQVSGATEKLEEFHRKLEEFSTLLQKAEEHEESQGPV
                     GTETDAINQQLDVFKIFQKEEIEPLQAKQQDVNWLGQGLIQSAAANTCTQGLEHDLDS
                     INARWKTLNKKVAQRTSQLQEALLHCGRFQDALESLLSWMADTEELVANQKPPSAEFK
                     VVKAQIQEQKLLQRLLEDRKSTVEAIKREGEKIAASAEPADRVKLSRQLSLLDSRWEM
                     LLSRAEARNRQLEGISVVAQEFHETLEPLNEWLTAVEKKLANSEPIGTQAPKLEEQIA
                     QHKVLEDDITSHNKQLHQAVSIGQSLKVLSSREDKDLVQSKLDSLQVWYFEIQEKSHS
                     RSELLQQALCNAKIFGEDEVELMNWLNEAHGKLSKLSVQDHSTEALWRQRAELRALQE
                     DILLRKQSVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSADVAKTLEH
                     ALQLAGQLQSKHKELCNWLDRVEVELLSYETQGLKGEAASQVQERQKELKNEVRNNKA
                     LLDSLNEVSSALLELVPWRAREGLEKTVAEDNERYRLVSDTITQKVEEIDAAILRSQQ
                     FDQAADAELSWITETQKKLMSLGCIRLEQDQTSAQLQAQKAFTMDILRHKDIIDELVT
                     SGHKIMTTSSEEEKQSMKKKLDKVLKKYDAICQINSERHLQLERAQSLVSQFWETYEE
                     LWPWLMETQQIISQLPAPALEYETLRRQQEEHRQLRELIAEHKPHIDKMNKTGPQLLE
                     LSPKEGVHIQEKYVAADTLYSQIKEDVKKRAVVLDEAISQSTQFHDKIDQILESLERI
                     AERLRQPPSISAEVEKIKEQIGENKSVSVDMEKLQPLYETLRQRGEEMIARSEGTEKD
                     ISAKAVQDKLDQMVFIWGSIHTLVEDREAKLLDVMELAEKFWCDHMSLVVTTKDTQDF
                     IRDLEDPGIDPSVVKQQQEAAEAIREEIDGLQEELDMVITLGSELIAACGEPDKPIVK
                     KSIDELNSAWDSLNKAWKDRIDRLGEAMQAAVQYQDGLQAIFDWVDIAGNKLATMSPI
                     GTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEEVDKHTVQDPLMEL
                     KLIWDSLDERIVSRQHKLEGALLALGQFQHALDELLAWLTHTKGLLSEQKPVGGDPKA
                     IEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSEGEEASNLQYKLRILNQRWQDI
                     LEKTDQRKQQLDSALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAREQLNA
                     HMEVCTAFAIKEETYKNLMLRGQQMLARCPRSVETNIDQDITNLKEKWESVKSKLNEK
                     KTKLEEALHLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTILFQIDEHKVFANE
                     VNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDEA
                     RKRAKQFHEAWSKLMEWLEDSEKSLDSELEIANDPDKIKAQLVQHKEFQKSLGGKHSV
                     YDTTNRTGRSLKEKTSLADDTLKLENMLSELRDKWDTICGKSVERQNKLEEALLFSGQ
                     FTDALQALIDWLYRVEPQLAEDQPVHGDIDLVMNLIDNHKVFQKELGKRTSSVQALKR
                     SARELIEGSRDDSSWVRVQMQELSTRWETVCALSISKQTRLESALQQAEEFHSVVHTL
                     LEWLAEAEQTLRFHGALPDDEDALRTLIEQHKEFMKKLEEKRAELNKATGMGDALLTA
                     CHPDSITTIKHWITIIQARFEEVLAWAKQHQQRLAGALAGLIAKQELLENLLAWLQWA
                     ETTLTEKDKEVIPQEIEEVKTLIAEHQTFMEEMTRKQPDVDKVTKTYKRRAADPPSLQ
                     SHIPVLDKGRAGRKRFPASGLYPSGSQTQIETKNPRANLLVSKWQQVWLLALERRRKL
                     NDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFID
                     GILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAYKPITDADKIEDEV
                     TRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMAL
                     DEFLVKNDPCRAKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTS
                     ASSHACQAASPQVPAAASTPKILHPLTRNYGKPWLANSKMSTPCKAAECPDFPVSSAE
                     GTPIQGSKLRLPGYLSGKGFHSGEDNALITTAASRVRTQFAESRKTPSRPGSRAGSKA
                     GSRASSRRGSDASDFDISEIQSVCSDVETVPQTHRPAPRAGSRPSTAKPSKIPTPQRK
                     SPASKLDKSSKR"
ORIGIN      
        1 atgatcgccg ccgctttcct cgttctgctg agaccctaca gcatccaatg tgccctcttc
       61 ctcttgttgc tcttgctggg caccatcgcc accatcatct tcttctgctg ctggcaccgc
      121 aagctccaga aagggaggca tccgatgaaa tcggtctttt cgggtcgttc cagaagcaga
      181 gatgctgccc tgagatctca tcactttcgt tctgagggat tccgagcgag cccccgacac
      241 atcaggaggc gagttgcagc ggctgcagct gcccggctgg aagaagtgaa gcctgtggtg
      301 gaagttcacc atcagagtga gcaagagtca tcagggagga agcggaggat caagaaaatt
      361 agccgggtgc agccggaatt ctatcactct gttcaaggtg cttcaaccag aaggcctagc
      421 tccgggaacg cgtcctaccg ctgttctatg tcctcctctg cggatttttc tgacgaggat
      481 gatttcagcc agaaatctgg ttcagcatct ccagctcctg gagacacctt accctggaat
      541 ttgcctaagc acgagagatc caaaagaaag attcaagggg gctcagtgct ggaccccgcc
      601 gagagggccg tgcttcggat agcagatgag cgggacaaag ttcaaaagaa aacatttaca
      661 aaatggataa atcagcatct catgaaggtt cgcaagcacg tgaacgatct ctacgaggat
      721 ctgcgggacg ggcacaattt gatctccctc ctggaggttc tgtccggaga caccttgccc
      781 cgagagaagg gtcggatgcg ctttcacagg ctacagaatg tacagattgc actcgactat
      841 ttgaaaagac gccaggtgaa gttagtgaac attaggaatg atgacataac agatgggaac
      901 cccaagctga cgttggggtt gatatggaca ataattctgc acttccagat atctgacatc
      961 catgtcaccg gagagtcaga ggacatgtct gcgaaagaaa ggttgctgct gtggacacag
     1021 caggcgacag aaggttatgc cggagtgcgg tgtgaaaact tcactacctg ctggagagat
     1081 gggaagctat ttaatgccat cattcataaa tacaggccgg acctgataga catgaatact
     1141 gttgctgttc aaagcaacct tgcgaattta gagcatgctt tttatgtagc tgaaaaaatc
     1201 ggtgtgatca gacttctgga ccccgaagat gtcgacgtct cttccccgga cgaaaagtca
     1261 gtgataacct atgtgtcctc cctctacgat gcatttccca aagtccccga aggcggcgaa
     1321 ggcattggtg caaacgatgt tgaagtcaag tggattgaat accagaacat ggtgaactac
     1381 ctcatccagt ggatcagaca ccacgtggtc acaatgtctg agagaacatt tcctaacaac
     1441 cctctagaac tcaaggcact ttataatcag tatttacagt tcaaagagaa agaaatccca
     1501 ccaaaggaga cagagaaatc aaaaattaaa cggctgtata aattattaga gatttggatt
     1561 gagtttgggc gcatcaaact ccttcaaggt tatcatccca acgacatcga aaaggagtgg
     1621 ggcaaactca tcatcgccat gctcgagcgg gagaaggcac tgcgtcctga ggtggagagg
     1681 ttggatatgc tgcagcagat tgctacccga gttcagaggg atagcgtcag ctgtgaggac
     1741 aaactcatgc tcgcccgaaa tgctctccag tctgattcca aaagattgga gtcgggagtg
     1801 cagtttcaga acgaagcaga aattgccggg tatatacttg aatgtgagaa ccttctacgc
     1861 cagcacgtga ttgacgttca gattctgcta gatgggaagt actaccaggc cgagcagctg
     1921 gtgcagaggg ttgccaagct gcgtgatgaa attctggcct taaggaatga atgttccgcg
     1981 gtgtacagca aaggacgcat gctgaccacg gagcagacca agctcatgat atcaggaatc
     2041 actcaaagct tgaactcagg atttgcacag accttacacc ccagtctgaa ctcagggcta
     2101 acccagagtt taaccccttc cttgacgtct tctagcgtga cttccggctt gtcgtccggg
     2161 atgacgtccc gcctgacgcc gtcggttact ccggcgtata cacctgggtt cccatcagta
     2221 gtagctccaa acttcagtgt aggagtagag ccaaattcat tacagaccct gaagctaatg
     2281 cagatccgaa agccccttct aaagtcatct ttgctggacc agaacttgac agaagaggaa
     2341 gtcaatatga aatttgttca agatctcttg aactgggttg atgagatgca ggtgcagctg
     2401 gaccgcactg aatggggctc agatctgcca agtgttgaaa gccatttaga aaaccataaa
     2461 aatgtccacc gagccattga agaatttgaa tctagtctta aggaggctaa aattagtgag
     2521 atccagatga cggcgcctct gaagctctct tacacggata agttgcacag actagagagt
     2581 cagtacgcta aactcctgaa cacatccaga aatcaggagc ggcacctcga tacgctccac
     2641 aactttgtaa cccgggcaac taacgaactt atctggttga atgaaaagga ggagtcagaa
     2701 gttgcctatg actggagtga gaggaacagc aacgtcgccc ggaagaaagg ctaccacgcg
     2761 gaactgatgc gggagctgga gcagaaggag gaaagtatta aagccgttca ggagatcgca
     2821 gagcagctgc ttctggaaag ccacccagcc cgcttgacca tagaggcata caaagcagcc
     2881 atgcagacac agtggagctg gatcctacag ctgtgccagt gtgtggagca gcacattcag
     2941 gagaacactg cctattttga gtttttcaat gatgccaaag aagccaccga ttacctaagg
     3001 aatctgaaag acgccattca gcgcaagtac gtctgtgacc gatccagcag cattcgcaaa
     3061 ctggaagacc tcgtccagga gtccatggag gaaaaggagg agctcctgca gtaccgaagc
     3121 gtggtggccg ggctgatggg gcgagcaaag acggtcgtgc agctgaagcc acggaatcct
     3181 gacaacccac tcaaaacgtc catcccgatc aaagctatct gtgactacag acagattgag
     3241 ataaccattt acaaagacga cgaatgtgtc ttggcaaaca actctcaccg cgccaagtgg
     3301 aaggtcatca gtcccaccgg aaacgaggcc atggtcccgt ctgtgtgctt taccgtcccc
     3361 ccaccaaaca aagaagcggt tgactttgcc aacagaatcg agcaacagta tcagagtgtc
     3421 ctcactcttt ggcatgagtc tcacgtaaac atgaagagta tagtgtcctg gcattatctc
     3481 gtcaatgaaa ttgacagaat ccgggctagt aacgtggctt cgataaagac aatgttgcct
     3541 ggcgaacacc agcaggttct cagtaatctc cagtcccgct tggaagattt tctggaggat
     3601 agccaggaat cccaaatatt ttcaggctcg gatataactc aactagaaaa ggaagtgaat
     3661 gtatgtagga agtattatca agagcttctc aagtctgcag aaagagagga gcaagaggag
     3721 tctgtgtaca atctgtacgt ctcagaagtg cgcaacatcc ggcttcgcct ggagagctgt
     3781 gaagaccggt tgattcggca gatccggacg cctctggaaa gagatgacct acacgaaagc
     3841 atgttgagaa tcacggagca ggagaaactg aagaaagagc tggaacggct taaagacgac
     3901 ttggaggcga tcacaaataa gtgtgaagag tttttcagcc aagcggcaga ttccccatcc
     3961 gtccctgccc tgcgatcaga gctcagcgtg gtcctccaga gcatgagtca gatctactcc
     4021 atgtctgcca cttacgtaga gaagttgaag actgttaatt tggttttaaa aaacacccaa
     4081 gctgcagaag cccttgtcaa actctacgaa accaagctgt gtgaagaaga agcagtcata
     4141 gctgacaaga ataacattga gaatttaatg agtacgttaa agcaatggcg atcagaagta
     4201 gatgagaaga gagaggtgtt ccacgcgttg gaagacgagt tgcagaaagc gaaagccatc
     4261 agtgacgaga tgttcaagac acacaaagaa cgggaccttg actttgactg gcacaaagaa
     4321 aaggcagacc agctcgtgga aaggtggcag agtgttcacg tccagatcga caacaggctg
     4381 cgggacttag aagggatcgg gaagtccctg aagcactaca gggactccta ccaccctcta
     4441 gatgactgga tccagcaaat cgaaacgacc cagagaaaaa ttcaggaaaa tcagccagaa
     4501 aacagcaaag ctctggccgt acagctgaac caacagaaga tgctggtatc tgaaatagag
     4561 gtgaagcaga gcaaaatgga cgagtgtcag aaatactcgg agcagtactc agctgccgtc
     4621 aaggactatg aattgcaaac aatgacctac agggccatgg tggattccca gcagaagtca
     4681 ccaatgaagc gtcggcggat acagagctcg gcggacctca ttattcaaga gttcatggac
     4741 ctacggacga ggtacactgc cctggtcact cttatgacgc agtacattaa attcgctggt
     4801 gattccttga aaaggctgga ggaggaggag aagtcactgg atgaagagaa gaaacagcat
     4861 gttgaaaagg ctaaagaatt gcagaaatgg gtatcaaata tcagcgagac actgggagat
     4921 ggggagagag ctgggaaacc tcacttctct aagcaacaga tttccagtaa agaaatatca
     4981 gccaagaagg agcagttctc ggaagctctt caaaacacac agattttttt ggctaaacat
     5041 ggagacaaac tgacagagga agacagaagt gacttggaga aacaggtgaa aactctgcag
     5101 gaaggttaca atttattatt cagtgaatct ctgaaacagc aagagttaca accctcagga
     5161 gaggcgaagg tcaaggtgga ggagaaggtt gtggcagagc gtcagcaaga gtacaaagag
     5221 aaactccaag ggctgtgtga cctcctcacc cagactgaaa accgcctaat tagtcaccag
     5281 gaaacctttg tgattggaga tggcacggtg gagttaaaga agtaccagtc caagcaagag
     5341 gaattacaga gggatatgca aggaagtaca caggccctgg cagaaatagt gagaaacaca
     5401 gaaatctttt tgaaagagag cggtgacgag ttgtcccaag aggataaggc tttgatcgag
     5461 cagaagctca acgaggcgaa ggtgaagtgt gagcagctga atttaaaggc cgagcagtcg
     5521 accaaggagc tggataaggt ggtgactgcg gccctcaagg aggagactga aaaggttgcg
     5581 gctgcgaggc agctggaaga gagcaaaacc aaaatagaaa accttctgaa ctggttgtca
     5641 aacgttgaga aagactcaga agggtcagga aggttgcaca cacaacccct ggagcagaat
     5701 ggaacccatt tgcatgaagg cgatggcacg tcggaagctg gtgaagagga tgaagtcaat
     5761 ggtaacctgc tggagacaga tgccgaaggg cacggtggga tgaccgaggg gaacctgaac
     5821 cagcagtacg agaaggtcaa ggcccagcat gaaaagatcg tggctcagca ccaggcggtc
     5881 atcatggcca cgcagtcggc gcaggcgctg ctggagaaac agggccacca tctgtcccct
     5941 gaagagaagg agaagctgca ggccaacgtg caggagctga aggcgcacta cgagacggtg
     6001 ctggccgagt gtgagaagaa ggtgaagctg acccactccc tgcaggagga gctggagaag
     6061 ttcgatgccg actgcggtga gtttgagcat tggctgcagc agtcggaaca ggagctggag
     6121 aacctggagg cgggcgcgga cgacctcagc gggctgacgg acaagctggc gaggcagaag
     6181 agcttctcgg aagacgtcat ttcgcacaaa ggcgacctga ggtacatcac catttccgga
     6241 aacagagtga tggaagctgc caaatcttgc agcaagagag acggtgacag gattggcaag
     6301 gacagccttg agacttccgc aacccacaga gaggttcaga ccaaactgga tcaggttaca
     6361 gaccgcttcc ggtgtctcta ctctaagtgc agtgttcttg gaaacaacct caaagatctg
     6421 gtggataaat accaacacta cgaagacgct tcctgtggac ttctctccgg gctccaggcc
     6481 tgcgaggcca aagccagcag acacttgctc gagcccatcg ctttggaccc caaaaatctg
     6541 caaaggcagt tagaagagac caaggctttg caaggacaga tatcaagtca gcaggctgct
     6601 gtagagaagc tgaagaaaac cgcagaagta ctcttggatg ccaagggctc gctacttcct
     6661 gccaagaatg acatccagaa gacgcttgat gacattgttg ggagatacga cgacctgtcc
     6721 aagtctgtga atgaacggaa cgaaaaactt cagataacgc tgacccgctc cctgagtgtg
     6781 caggacggtt tggacgagat gctggactgg atgggaagtg tggaaagctc actggtcaaa
     6841 caaggtcaag tgcccttaaa ctccacagca ctccaggacc tcatcagtaa aaacatcatg
     6901 ctggatcagg atattacggg tcgtcagagc agcataaacg ccatgaacga aaaggtgaag
     6961 acatttatag agacaacaga cccatccact gcctcctcgc tgcaggcaaa aatgaaggac
     7021 ctgtctgctc gcttttccga agcgagtcag aaacacaagg aaaagctcgc caagatggtg
     7081 gagctgaagt ccaaagtaga ggagtttgag aagctctcag acaagctcca gacattcctc
     7141 gagacacaga gccaggcgct cactgaggtg gacatgccgg gaaaggacgt gccagagctg
     7201 tctcagcata tgcaggaatc cactactaaa ttcttagaac acaggaaaga tctcgaagct
     7261 ttgcacagcc tcctgaaaga gatatccagc cacggcttac caggggacaa agctctggtg
     7321 tttgagaaaa ctaataattt gtcaaagaaa ttcaaagaac tggaggatac tatccaagaa
     7381 aaaaaagaag ctctcagttc atgtcaggag cagctgagtg ctttccacga cctcgctcag
     7441 tccctgaaaa catggataaa agaaacaacc aagcaggttc ccatcgtgaa gccttctttc
     7501 ggcacagagg acttggaaaa atctctggag gaaaccaaga aattacaaga aaagtggagt
     7561 ctgaaaaccc cagaaattca caaagcaaac aacagtgggg tctcactatg taacctgcta
     7621 agtgcactga tcagccctgc aaaggccata gcggcggcca gatcaggtgg agtaatacta
     7681 aatggtgaag gaacagacac aaatactcag gatttcttgg caaataaagg tttaacatct
     7741 attaaaacag acatgactga cataagccac agttacgaag acctgggcct cttactcaag
     7801 gacaaaatag tggagctgaa caccaagctc tcgaagctgc aaaaggctca ggaagagtcg
     7861 agcgcaatga tgcagtggtt gcagaagatg aacaagacag ccagcagatg gcgccagaca
     7921 cccaccccgg cagactccga gtccgtgaag attcaggtgg agcagaacaa gtcgtttgag
     7981 gcagaactga agcaaaacgt aaacaaagtg caagaattga aagacaaact ggcagagctt
     8041 ctgaaggaga acccggaggc tcccgaggcg ccatcctgga agcagacgat ggcagagatg
     8101 gacactaagt ggcaagaact caaccagtta accattgaca ggcaacaaaa gctggaagag
     8161 tcctccaata atctaagcca gttccagacc acagaggccc agttaaagca gtggctcgtg
     8221 gagaaggagt tgatggtcag cgtgctcggg cccttgtcca ctgacccaaa catgttgaac
     8281 actcagaagc agcaggccca gattctgcta caagaattcg acacccggaa accacagtac
     8341 gaacagctca cagcagctgg ccagggcatc ctgagcaggc ctggggaaga cccctctttg
     8401 catgggattg taaaggagca actggcagct gtgacccaga agtgggacaa cctaacaggg
     8461 caactgaggg acagatgcga ctggattgac caggctattg tcaaaagcac acagtaccag
     8521 agcctgctga gaagtctttc cggtaccctg acggagctgg atgaaaagct cagcagcagc
     8581 ctcatctcag gcacactgcc cgatgccgtg aaccagcagc tggaggcagc ccagaagctg
     8641 aagcaggaaa tcgagcagca aacaccgaag atcaaggagg cccagacgct ctgtgaggac
     8701 ctgtcggcac tggtcaaaga agagtacttg agagcagaac tgagcaggca gctggaaggc
     8761 gtcctaaagt cctttaagga tattgaacaa aagacagaga atcatgttca gcacctccag
     8821 tcagcctgcg caagctctca ccagtttcag caaatgtcta aggactttca ggcgtggctt
     8881 gacgcaaaga aagaagagca gaggaactct cccccaatat ccgccaagct ggatgtcttg
     8941 gagtcgttac tcaaagcgca gaaagacttc ggcaaaactt tcaccgagca gtctaacatt
     9001 tatgagaaaa cggttgcaga aggggaaaac ctgttgtcaa agacacaggg ggcggagaag
     9061 gcagccctgc agttgcagct taacaccatc aaaacagact gggaccgatt caggaagcag
     9121 gtgaaagaaa gggaagagaa gctgaaggag tcgttggaaa aagccctcag atacagggag
     9181 caggtggaca ctctgcagcc gtgggtagac aagtgtcagc acagcctgga gagtgtaaag
     9241 ctctccctgg atcccgctga cacagagcgc tccatcacgg agttaaagac tctgcagaag
     9301 gaaatggacc accactttgg aacgctggaa ctactgaaca attcagccaa tagcctgctc
     9361 agcgtctgcg aggtagataa agaagtggtc acggagggga ataagtcact gatccagaag
     9421 gtgaatgttg tcactgagca gctccaaagt aagaaggtct ccctggagaa catggcccag
     9481 aagtttaagg aatttcaaga agtttccaaa gacgccaaaa ggcagcttca ggatacaaag
     9541 gaacagctag aggtctatca gtccctggga ccccaggcct gcagcaacaa gcacctcacc
     9601 atgctgcagg ctcagcagaa gtcgctgcag accctgaagc atcaggtaga ctcggccaga
     9661 aggcttgctc aggacctcgt gatggaagcc acagacccaa agggaacctc tgacgtgttg
     9721 tcacaagcgg agacgttagc cgaagagcac aggggactga gccagcaggt ggacgagaag
     9781 tgttctttct tagaaaccaa gctgcagggt ctcggccact tccagaatac catccgagag
     9841 atgttctctc agtttacgga gtttgatgac gagctggata gcatggctcc agtggggaga
     9901 gacgtggaga cactgcaaaa gcaaaaggcg tccatgcaaa cctttctgaa gaagctggaa
     9961 gccctcatca cgagcaacga cagtgccaac agaacctgca agatgatgct agccaccgag
    10021 gagacctctc ctgaccttat cggagtcaaa agggacttag aagccttgag caagcagtgc
    10081 aacaagctgc tggaccgagc caagaccaga gaggagcagg tcagtggggc cacggagaag
    10141 ctcgaagagt tccaccgcaa gctggaagag ttctccaccc tgctccagaa ggctgaagaa
    10201 cacgaagagt cccagggccc cgtggggaca gagacagacg caattaacca gcagctcgac
    10261 gtgtttaaga tattccagaa agaagagatc gaacccttgc aggcgaagca gcaagatgtg
    10321 aactggttag gccaaggcct tattcagagc gcagctgcaa acacctgcac tcagggtttg
    10381 gagcatgacc tggacagcat caatgcaagg tggaagaccc tcaataagaa ggtggctcaa
    10441 cgaacatccc agctgcaaga ggccctgctc cactgtggac ggttccagga tgccctggag
    10501 tccttgctca gctggatggc agacacggaa gagcttgtgg ccaatcagaa gcctccatca
    10561 gcagagttca aagtggtgaa ggcccagata caggagcaaa agcttctgca gaggctgctg
    10621 gaagaccgga agtctaccgt ggaggcgatc aaacgagaag gagagaaaat cgctgcttca
    10681 gcagagccgg cagaccgagt gaagctctcc aggcagctga gcctcctgga cagtagatgg
    10741 gaaatgctgc ttagcagagc cgaagcaagg aaccgtcaac tggaaggtat ctctgtggta
    10801 gctcaggagt ttcatgagac cttggagccc ctgaatgagt ggctcacagc cgtagaaaaa
    10861 aagctggcca actccgaacc cataggaacc caggcaccca agctggagga acagattgca
    10921 cagcacaaag tattagaaga tgacatcacc agtcacaaca aacagttaca ccaggccgtt
    10981 agcatcggcc agtccttaaa ggtcctgagc tccagggagg acaaagatct ggtgcagagt
    11041 aagctagact ccttgcaagt gtggtacttt gagattcaag agaaaagtca cagcaggtct
    11101 gagctcctcc agcaggccct gtgcaatgct aagatctttg gggaagatga agttgagctg
    11161 atgaactggc tgaacgaagc acatggcaag ctgagtaagc tgtcagtcca ggatcacagc
    11221 acagaggcgc tgtggagaca gcgggccgaa ctcagggctc tacaagaaga cattctcctc
    11281 aggaaacaga gtgtagatca ggcactgctg aacggcttag aactgctcaa acaaaccaca
    11341 ggcgacgaag tcttaatcat tcaagacaag ttggaagcca ttaaagccag gtacaaagac
    11401 atcaccaagt taagtgccga cgtggcgaag actctggaac acgccctgca gctcgctgga
    11461 cagctgcagt ccaagcataa ggagctgtgc aactggctgg acagagtgga ggtggagctg
    11521 ctgtcctacg agactcaggg cctgaaggga gaagctgcaa gccaagtgca agagagacag
    11581 aaagaactga aaaatgaagt caggaacaac aaagccttac tggattctct caatgaggtg
    11641 agcagcgcct tgttggaact ggtgccctgg agggcaagag aagggcttga gaagacggtc
    11701 gccgaggaca acgaacgcta ccgattggtg agcgacacca tcacacagaa agtggaagag
    11761 attgatgctg ccattctgag gtctcagcag tttgaccaag cggcagatgc tgagttatcc
    11821 tggatcactg aaacacagaa gaaattaatg tctctgggtt gcatcaggct ggagcaagac
    11881 cagacctctg ctcagctgca ggctcaaaag gctttcacca tggatatctt gagacacaag
    11941 gatatcattg acgaactcgt tacctctggg cataaaatca tgaccacatc cagcgaagag
    12001 gagaagcagt caatgaagaa aaaactggac aaggttctga agaagtacga cgccatctgc
    12061 cagatcaact cagagaggca cctgcagctg gagcgggcgc agtccctcgt tagccagttc
    12121 tgggagacct atgaggaact ttggccgtgg ctaatggaaa cacaacaaat catctctcag
    12181 ctaccggccc cagccctgga gtacgagact ctgaggagac agcaagagga gcatcggcaa
    12241 ctgcgagagc tgatagcgga acacaagcct cacatagata agatgaacaa gaccgggccg
    12301 cagctgctgg aactgagccc caaggaaggc gtccatatcc aggaaaagta tgtggcagcc
    12361 gacaccctct acagccaaat taaagaagat gtcaaaaagc gagccgtggt actggatgag
    12421 gccatttctc agtccaccca gtttcacgac aagatcgacc agatccttga gagcctggag
    12481 cgcatcgcgg agcgtctacg gcagccgccg tccatctctg ccgaggttga aaagatcaag
    12541 gagcagattg gtgaaaacaa gagtgtgtcc gtggacatgg agaagctgca gccgctgtat
    12601 gagactctga ggcagagggg agaggagatg atcgccaggt ctgagggcac cgaaaaagac
    12661 atatctgcca aagctgtgca ggataagttg gaccaaatgg ttttcatctg gggaagcatc
    12721 cacaccctgg tggaagacag ggaagccaag ctgctggacg tgatggaact agcagagaaa
    12781 ttctggtgtg atcacatgtc gctggttgtt accaccaaag acactcaaga tttcatccgg
    12841 gacctggagg atcccggaat cgatccctcg gtagtaaagc agcagcagga agcagcagag
    12901 gcaataagag aggagattga tggactgcaa gaggagctcg acatggtcat cacactgggc
    12961 tcagagctca ttgccgcctg tggggagcct gataagccca tcgtcaagaa gagtatagac
    13021 gagttgaact cagcgtggga ttctctaaat aaagcctgga aagaccggat tgacagactg
    13081 ggagaggcca tgcaagccgc cgtccagtac caggatggat tgcaggcaat attcgactgg
    13141 gtcgatatcg caggcaataa gctagccaca atgtctccca tcggaacgga cttggagacg
    13201 gtcaagcagc agattgaaga gctgaagcaa tttaagtcag aagcttacca acaacagata
    13261 gaaatggaaa gactgaacca ccaagcagaa cttttgctga agaaagtaac agaggaggtt
    13321 gacaagcaca ccgtccagga cccgctgatg gagctgaaat tgatatggga cagcctggac
    13381 gagcgaattg tcagcagaca gcacaaactt gagggtgctc tcttggcgct gggtcagttc
    13441 cagcacgccc tggacgagct cctcgcatgg ctgacacaca ccaagggctt gctgagtgaa
    13501 cagaaacctg ttggaggaga cccgaaagcc atcgagatcg aacttgctaa gcatcacgtg
    13561 ctccaaaatg acgtcctagc ccaccagtcc accgtggagg ccgtcaacaa agcaggaaat
    13621 gacctcatcg agtcaagtga gggcgaagaa gcaagcaacc tccagtacaa gctcagaatt
    13681 ctgaatcagc gctggcagga tattttggaa aagacagatc aaaggaagca gcagctggac
    13741 agcgccttgc gccaggccaa agggttccat ggtgaaattg aggatctgca acagtggctg
    13801 acggacacag agcgtcatct cctggcatcc aaacctctgg gaggtctacc ggagacagcc
    13861 agagagcagc ttaacgcaca tatggaagtc tgcaccgcct ttgccatcaa agaagagaca
    13921 tacaagaacc tgatgctgag gggacagcag atgctcgcac gatgccccag gtctgtggaa
    13981 accaacattg accaagacat aaccaacttg aaggagaagt gggaatccgt gaaaagcaaa
    14041 ctcaacgaga agaagacaaa attggaagag gccctgcact tggccatgga attccacaat
    14101 tccctccagg acttcatcaa ctggcttacc caggctgagc aaactttgaa cgtggcttcc
    14161 cggccaagtc ttatcttgga caccatcttg ttccaaattg atgaacacaa ggtctttgcc
    14221 aacgaagtga attcacaccg tgagcagata atagagctag acaaaactgg aacccacctg
    14281 aagtatttca gtcagaaaca agacgtcgtg ctcattaaga acctgctgat cagcgtgcag
    14341 agtcggtggg aaaaggtggt tcagcgctta gtagagagag gaagatcctt ggacgaagcg
    14401 aggaagaggg ccaagcagtt ccacgaagct tggagtaagc tgatggaatg gctggaagac
    14461 tcagaaaaat ccctggattc tgaactggaa atcgccaacg atccagacaa aatcaaagca
    14521 cagctggttc agcacaagga gtttcagaaa tcactcggag gcaaacattc tgtgtacgac
    14581 accaccaatc ggactggacg ttctctgaag gagaaaactt ccctggccga cgacaccctg
    14641 aagctggaga acatgctgag cgaactcagg gacaaatggg acaccatctg tggaaagtcc
    14701 gtggaaagac aaaacaaact ggaggaagcc ctgttgtttt ccgggcagtt cacagatgcc
    14761 ctgcaggccc tcattgattg gctgtatcgg gttgagcccc agctggcaga agaccaacct
    14821 gttcacggag acattgactt ggtgatgaac ctgatcgata atcacaaggt cttccagaaa
    14881 gagttgggga agaggaccag cagcgtgcag gccctgaagc gctctgccag ggagctcata
    14941 gaaggcagcc gggatgactc ctcctgggtc agggtccaga tgcaggaact aagcacccgc
    15001 tgggagacgg tgtgcgcgct ctcgatatca aagcagacgc ggctagaatc agccctgcaa
    15061 caggcagagg aattccactc tgtggtccac acccttttgg agtggctggc agaggcagag
    15121 caaacgctgc gtttccatgg cgcgctccca gacgacgagg atgctctccg gactcttatt
    15181 gagcaacata aagagttcat gaagaaactg gaagagaaaa gagcagaact aaataaggcc
    15241 acaggtatgg gggacgctct cctgaccgcc tgccaccctg actccattac caccattaag
    15301 cactggataa ccatcatcca ggccaggttt gaagaggtgc tggcctgggc aaagcagcac
    15361 cagcagaggt tagcaggggc gctggcaggg ctcatcgcta agcaggagct gctggagaat
    15421 ttgctcgcct ggctgcagtg ggctgaaacc acactgaccg agaaagataa ggaagtcatc
    15481 ccccaggaga tcgaagaggt gaaaaccctc attgcagaac accagacctt catggaagaa
    15541 atgaccagaa aacagcctga tgttgataaa gttaccaaga cctataagag gagggccgct
    15601 gaccctccat ccttacagtc tcacatcccc gtcttggaca agggacgagc cggaaggaaa
    15661 cgcttcccag cctcaggcct gtatccttca gggtcacaga cgcaaatcga aaccaagaac
    15721 cccagggcta acttgctggt gagcaagtgg cagcaggttt ggctcctggc cttggaacga
    15781 aggaggaagc tcaacgacgc cttggacagg ctggaggagc tgagggaatt cgctaacttc
    15841 gattttgata tctggcggaa aaaatacatg aggtggatga atcataagaa gtcgagagtg
    15901 atggatttct tccggagaat cgataaggac caggatggga agatcactcg gcaggaattc
    15961 attgacggca ttctgtcctc caagtttcct accagtcgtc tggagatgag cgccgtggca
    16021 gacatctttg acagagacgg agatgggtac atcgactact atgaattcgt ggccgctcta
    16081 catccaaaca aagatgcgta caaacccatc acggacgctg acaaaatcga agatgaggtc
    16141 acgaggcagg tggccaagtg taagtgcgcc aagcggttcc aagttgagca gatcggagac
    16201 aacaaataca ggttcttcct gggaaatcag tttggagact cccagcagct gcgactggtt
    16261 cggatcctgc gaagcaccgt gatggtccgt gttggaggtg gatggatggc tctggatgag
    16321 ttcttagtga aaaacgatcc gtgcagggcc aaaggaagga ccaacatgga gctgcgggag
    16381 aagttcatct tagcggacgg ggccagccag ggtatggctg ccttccgacc acgaggccgc
    16441 cgatctcggc cttcgtcgag aggagcttcc cccaacagat ccacttccgc atccagtcac
    16501 gcctgccagg cagcctcccc acaggtgcct gctgccgcca gcacacccaa gattctgcac
    16561 cctttaacac gcaattatgg taaaccatgg ttggcaaaca gcaaaatgtc aactccttgt
    16621 aaagcagcag aatgcccaga ctttcccgtg tcatctgccg agggaacgcc aatccaggga
    16681 agcaagctgc ggctgccagg gtacttgtca gggaaaggtt tccactccgg ggaggacaac
    16741 gccttgataa cgaccgcagc ctccagagtc cgaacgcagt ttgctgagtc caggaagacg
    16801 cccagccgcc ctggaagcag agccggaagc aaagccggga gcagagccag cagccgccga
    16861 ggcagcgacg cgtccgactt tgacatttca gaaatccagt ctgtgtgctc agacgtggag
    16921 accgtcccac agacacacag acctgcgccc cgagcaggtt ctcggccatc cacagccaag
    16981 ccttctaaaa tccccacgcc ccagaggaag tcacccgcca gcaaactaga caagtcttcg
    17041 aagagatag
//
