LOCUS       NM_001191079            3904 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus desmoglein 3 (Dsg3), mRNA.
ACCESSION   NM_001191079 XM_001061524 XM_017600921
VERSION     NM_001191079.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3904)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On or before Sep 30, 2022 this sequence version replaced
            XM_017600921.2, NM_001191079.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.56757.1,
                                           SRR26643295.55608.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680453, SAMN09345330
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               JAXUCZ010000018.1  12074321-12074477
            158-193             JAXUCZ010000018.1  12084362-12084397
            194-325             JAXUCZ010000018.1  12085114-12085245
            326-481             JAXUCZ010000018.1  12086097-12086252
            482-626             JAXUCZ010000018.1  12086670-12086814
            627-793             JAXUCZ010000018.1  12087401-12087567
            794-922             JAXUCZ010000018.1  12088335-12088463
            923-1108            JAXUCZ010000018.1  12088921-12089106
            1109-1380           JAXUCZ010000018.1  12091742-12092013
            1381-1520           JAXUCZ010000018.1  12092789-12092928
            1521-1748           JAXUCZ010000018.1  12095363-12095590
            1749-2003           JAXUCZ010000018.1  12097203-12097457
            2004-2146           JAXUCZ010000018.1  12100382-12100524
            2147-2210           JAXUCZ010000018.1  12100796-12100859
            2211-2428           JAXUCZ010000018.1  12103200-12103417
            2429-3904           JAXUCZ010000018.1  12104479-12105954
FEATURES             Location/Qualifiers
     source          1..3904
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..3904
                     /gene="Dsg3"
                     /note="desmoglein 3"
                     /db_xref="GeneID:291752"
                     /db_xref="RGD:1592103"
     exon            1..157
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..3241
                     /gene="Dsg3"
                     /codon_start=1
                     /product="desmoglein-3 precursor"
                     /protein_id="NP_001178008.2"
                     /db_xref="GeneID:291752"
                     /db_xref="RGD:1592103"
                     /translation="MACLFPRALRLLSLLMVVLMVYGELHIESGGQHREDRMALQLTK
                     RRYKREWVKFAKPCREREDNSKRNPIAKITSDFQKNQKITYRISGVGIDQPPFGIFVV
                     DPNNGDINITAIVDREETPSFLITCRALNALGQDVERPLILTVKILDVNDNAPIFSQT
                     IFKGEIEENSASNSLVMILNATDADEPNHMNSKIAFKIVSQEPAGMSMFLISRNTGEV
                     RTLTSSLDREQVGSYHLIVSGADNDGTGLSTQCECSIKIKDVNDNFPVLTDSQYSARI
                     EENTLNSELLRFQVTDWDEEYTDNWLAVYFFTSGNEGNWFEIETDPRTNEGILKLVKV
                     LDYEQMQSMQFSIAVRNKAEFHQSVISQYQVQSTPVTIQVINVQEGISFRPPSRTFTV
                     QRGVSINKLAGYILGTYQATDEDTGKAASSVRYVLGRNDGGFLVIDSKTAEIKFVKNI
                     NRDSTFIVNKTISAEVLAIDENTGKTSTGTVYVEVPSFNENCPSVVLEKREICTSSPS
                     VTLSVRTLDRAKYTGPYTVSLEEQPLKLPVVWTITTLNATSALLQAQQHISPGVYNVP
                     VIVKDNQDGQCDTLESLTLTVCQCDDRSMCRAPGPSREPFIREESTWRLGPAAIGLIL
                     LGLLMLLLAPLLLLTCDCGSGPIGGAGTGGFVPVPDGSEGTIHQWGIEGAQPEDKEIT
                     NICVPPVTSNGADFMESSEVCTNTYAGGTLVEGASGMEMTTKLGGATGSGAAVALGLG
                     HSGTMRTRHSTGGTLKDYAAPVNMTFLGSYFSQKSSAYAEEEDDREVNDCLLIYDDEG
                     EDAAPRSPALSSCSFMADDLDDSFLDSLGPKFKKLAEICLGVDDEAKQVKPGPKDSSS
                     GADACARPTEALQAGSNRYQTLPGSLEVTQSGSSRYQTLPGGLEVTQSGSNRYQTLPG
                     GLEVTQSGSNRYQTLPGGLEVTQSGSKVCHVLPGNQDTSVLSSSGSVHPAIAIPDPLQ
                     LGNYLLTETYTTSGSFVQPTTATFDPHVTQNVTVTERVICPLPSASGSIVAPTELRGS
                     YSMLYTKEACSHL"
     exon            158..193
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            194..325
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            326..481
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            482..626
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            627..793
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            794..922
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            923..1108
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1380
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1520
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1521..1748
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..2003
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            2004..2146
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            2147..2210
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            2211..2428
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
     exon            2429..3904
                     /gene="Dsg3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agacatcaga gccaccactg ccagacggga gcttcagaca taggatacag acacccaggt
       61 gaagagctgc agccagaggc ttggatttat tcaccagaga ctcgtgacaa tggcctgcct
      121 attccccaga gccctgaggc ttctgtccct cctgatggtg gtgctcatgg tgtacgggga
      181 actacacata gagtcgggag gacagcacag agaagacagg atggcattgc agctgaccaa
      241 aaggaggtac aaacgtgaat gggtgaaatt tgcaaagccc tgcagagaaa gagaagacaa
      301 ctcaaaacga aacccaattg ccaagatcac ttcagatttc caaaaaaatc agaaaattac
      361 ttaccgcatt tccggagtgg gaattgatca gccccctttc gggatctttg ttgttgaccc
      421 aaacaatggc gacatcaaca taacagccat agttgatcgt gaggaaaccc caagcttcct
      481 gatcacatgc cgagccctta atgccctggg acaagatgta gagagaccac ttatactgac
      541 agtgaaaatt ttagatgtca atgataatgc tccaatattt tcacaaacca tattcaaggg
      601 tgaaattgaa gaaaacagtg cttcaaattc cctggtgatg atcctaaatg ccacagacgc
      661 ggacgagcca aaccatatga actctaaaat cgccttcaaa attgtctccc aggagcccgc
      721 cggcatgtcc atgttcctca tcagcagaaa caccggagaa gtccgcactt tgaccagttc
      781 tctcgatcga gagcaagttg gtagctacca tttgattgtg agcggtgcag acaacgatgg
      841 aacaggactg tcgactcagt gtgaatgtag tatcaaaatt aaagatgtca acgacaactt
      901 cccagtgctt acggactcgc agtactcagc acgtattgag gaaaatactt tgaattcaga
      961 gttactccga tttcaagtga cagactggga tgaagaatac acagataatt ggttggctgt
     1021 gtatttcttt acctctggga atgaagggaa ttggtttgaa atcgaaacag atcctagaac
     1081 caatgaaggc atcctgaagt tggttaaggt tctggattat gaacaaatgc aaagtatgca
     1141 atttagtatt gccgtgagga acaaagctga gttccaccag tcagtgatct ctcagtacca
     1201 agtgcagtca actccagtca caattcaagt catcaatgtc caagagggga tttcattccg
     1261 tcctccttcc aggacattta ctgtgcaaag gggtgtaagc attaacaaat tagctggtta
     1321 catcctgggg acataccaag cgacggatga ggacactggt aaagctgcct cctctgtcag
     1381 atatgtcctg ggtcgtaatg atggtggttt tcttgttatt gattcaaaaa ctgctgagat
     1441 caaatttgta aaaaacatca accgagattc cactttcata gttaacaaga caatctctgc
     1501 tgaggttctg gccatagacg aaaacactgg taagacctcc acaggcacag tatatgtgga
     1561 agtgcccagt tttaatgaaa actgtccatc agttgtcctg gagaagagag agatctgtac
     1621 atcctcacca tcggtgaccc tctcagtgag aaccctggac agggctaaat acactggccc
     1681 ctacacagtg tctctggagg agcagccact gaagctgccg gttgtgtgga ccatcacgac
     1741 gctgaatgct acctcagcac ttctacaagc ccagcagcat atctctccag gagtgtacaa
     1801 tgtcccagtc atcgtgaagg acaatcagga tgggcagtgt gacacactag agagcttgac
     1861 cctgacagtg tgtcagtgtg atgaccggag catgtgcaga gcccctggcc cgagcagaga
     1921 gccttttatc cgtgaggagt caacctggag gctggggcct gctgctattg gcttgatcct
     1981 gctaggactc ctgatgttgc tactggcccc acttctgctt ctgacctgtg actgtgggtc
     2041 aggtcccatc ggaggagcag ggacaggtgg ctttgtccca gtgcccgatg gctcggaagg
     2101 aacgattcat cagtggggaa tcgaaggagc tcagcccgaa gacaaggaaa tcacaaatat
     2161 ttgtgttcct ccagtcacaa gcaatggagc agattttatg gaaagttctg aagtttgcac
     2221 aaatacctac gctggaggga ccctagtaga aggtgcttcc ggaatggaga tgactaccaa
     2281 gctaggagga gctacgggat caggagctgc agtggcgctt ggcttgggtc attcaggaac
     2341 gatgagaacg aggcattcca ctggagggac cttgaaggat tatgctgcac cagtgaacat
     2401 gactttccta ggatcctact tctctcagaa atcatccgcc tatgctgagg aagaggatga
     2461 tcgtgaagtg aatgactgtt tgctgatcta cgatgacgaa ggcgaggatg ctgccccccg
     2521 ttccccagcc ctcagctcct gcagctttat ggccgatgac ctggacgaca gtttcttgga
     2581 ctcccttggc cccaaattta aaaagcttgc agagatatgt cttggcgttg atgacgaagc
     2641 caagcaagta aagccaggcc ctaaagacag tagttctggg gctgacgcct gtgctcgccc
     2701 tacagaagcc cttcaggcag gttctaacag gtaccagact ttgcctggca gtctagaagt
     2761 cactcagtcg ggttctagca ggtaccagac tttgcctggc ggtctggaag tcactcaatc
     2821 gggttctaac aggtaccaga ctttgcctgg cggtctggaa gttacccagt cgggttctaa
     2881 caggtaccag actttgcctg gcggtctgga agtcacccaa tcaggttcca aagtgtgcca
     2941 cgtgttgcct ggcaaccaag atacttctgt tttgtcctct tctgggtctg tccaccctgc
     3001 tattgccatc cctgatcctc tacagcttgg taactacttg ctcacagaaa cttacacaac
     3061 atcaggttcc tttgtgcaac ccaccactgc cacctttgac ccacatgtca ctcaaaatgt
     3121 cactgtaaca gaaagagtca tttgccccct tcctagtgcc tctggcagca tagtggctcc
     3181 cacagagctt cgaggctcct acagtatgct ctatacaaaa gaagcctgtt cccatctatg
     3241 accaaagcaa actggaaaaa cgtaccagac aaatttgggt atttgtacct tttttaaatt
     3301 tagcaatgct agcactgttg gactaatttg gctcttagtg gataatctct gatcataagt
     3361 ataattcaaa tattctgact catataccaa agctgggtat gttatcattt ctgattatct
     3421 gatttttttc cagcagagca aacctgtgta tatttttttt aattatctaa gatgttagac
     3481 aggaatatgt cccaagcatc ttctcatttc tctattatca acaccaaaag aagatgctgt
     3541 caccttaaaa tgcagtgtgg gttagtagat tggcttcctt cttggaatgc aagttcctgt
     3601 ctctaacacc tattctggtg tcactaataa ggatatgaga gtattattaa tagcaatggg
     3661 gatttgaggt gcttggttta ccttacaggg cagcttggaa taaaggcaat agatgcagct
     3721 ggggtttttt ggtttgttgt ttttggtttt ggttttagtt ttagtttgtt ttgtcatttg
     3781 gtaaggaaac tcaaaacgta tttttatgag tgaaaaacct gtttaacttg ccatacctat
     3841 gtgctgtgta tcttttttaa aaagataatt ttgaaataca aatatcatag aacatgtaaa
     3901 aaaa
//
