LOCUS       NP_001102403             958 aa            linear   ROD 23-MAR-2023
DEFINITION  dermatan-sulfate epimerase precursor [Rattus norvegicus].
ACCESSION   NP_001102403 XP_001053297 XP_345111
VERSION     NP_001102403.1
DBSOURCE    REFSEQ: accession NM_001108933.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 958)
  AUTHORS   Maccarana M, Olander B, Malmstrom J, Tiedemann K, Aebersold R,
            Lindahl U, Li JP and Malmstrom A.
  TITLE     Biosynthesis of dermatan sulfate: chondroitin-glucuronate
            C5-epimerase is identical to SART2
  JOURNAL   J Biol Chem 281 (17), 11560-11568 (2006)
   PUBMED   16505484
REFERENCE   2  (residues 1 to 958)
  AUTHORS   Nakao M, Shichijo S, Imaizumi T, Inoue Y, Matsunaga K, Yamada A,
            Kikuchi M, Tsuda N, Ohta K, Takamori S, Yamana H, Fujita H and Itoh
            K.
  TITLE     Identification of a gene coding for a new squamous cell carcinoma
            antigen recognized by the CTL
  JOURNAL   J Immunol 164 (5), 2565-2574 (2000)
   PUBMED   10679095
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474016.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_345111.3, XP_001053297.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC168891.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA5760383, SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q11"
     Protein         1..958
                     /product="dermatan-sulfate epimerase precursor"
                     /EC_number="5.1.3.19"
                     /note="squamous cell carcinoma antigen recognized by T
                     cells 2"
                     /calculated_mol_wt=107488
     sig_peptide     1..22
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
                     /calculated_mol_wt=2427
     CDS             1..958
                     /gene="Dse"
                     /gene_synonym="Sart2"
                     /coded_by="NM_001108933.1:489..3365"
                     /db_xref="GeneID:365583"
                     /db_xref="RGD:1305079"
ORIGIN      
        1 mrthtrgapt vfficllccv sayitdenpe vmipftnany dshpmlyfsr kdvaelqlra
       61 asshehiaar lteavhtmlt npleylppwd hkeysarwne iygnnlgala mfcvlypeni
      121 earemakdym ermaaqpswl vkdapwdevp lahslvgfat aydflynyls ktqqetflev
      181 ianasgymye tsyrrgwgfq ylhnhqptnc malltgslvl mnqgylqeay lwtkqvlsim
      241 ekslvllrev tdgslyegva ygsyttrslf qymflvqrhf dinhfghpwl khhfafmyrt
      301 vlpgfqrtva iadsnynwfy gpesqlvfld kfvmrngsgn wladqirknr vvegpgtpsk
      361 gqrwctlhte flwydaslks vppldfgtpt lhyfedwgvv tygsalpaei nrsflsfksg
      421 klggraiydi vhrnkykewi kgwrnfnagh ehpdqnsftf apngvpfite alygpkytff
      481 nnvlmfspav skscfspweg qvtedcsskw skykhdlaas cqgrviaaee kdgvvfirge
      541 gvgaynpmln lknihrnlil lhpqllllvd qihlgeespl etaasffhnv dvpfeetvvd
      601 gvhgafirqr dglykmywmd dtgysekatf asvtyprgyp yngtnyvnvt mhlrspitra
      661 aylfigpsvd vqsfsihgdp qrldvfvats ehayatylwt gentgqsafa qviadhqkil
      721 fdqssaikst tvpevkdyaa ivernlqhfk pvfqllekqi lsrvqntasf rktaerllrf
      781 sdkrqteeai drifaisqqq rqqrgkskks rrtgkhykfv davpdifaqi evnekkirqk
      841 aqilaqkeqp idedeemkdl ldfadvtyek hrnggsmkdg fgqarmvtsh nrapslsasy
      901 trlflilnia iffvmlamql tyfqraqslh gqrclyavll idscvllwly sscsqsqc
//
