LOCUS       NM_133587               6656 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus DS cell adhesion molecule (Dscam), mRNA.
ACCESSION   NM_133587 XM_346413
VERSION     NM_133587.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6656)
  AUTHORS   Purohit,A.A., Li,W., Qu,C., Dwyer,T., Shao,Q., Guan,K.L. and Liu,G.
  TITLE     Down syndrome cell adhesion molecule (DSCAM) associates with
            uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse
  JOURNAL   J Biol Chem 287 (32), 27126-27138 (2012)
   PUBMED   22685302
REFERENCE   2  (bases 1 to 6656)
  AUTHORS   Shen,L., Xiao,Z., Pan,Y., Fang,M., Li,C., Chen,D., Wang,L., Xi,Z.,
            Xiao,F. and Wang,X.
  TITLE     Altered expression of Dscam in temporal lobe tissue from human and
            experimental animals
  JOURNAL   Synapse 65 (10), 975-982 (2011)
   PUBMED   21360594
  REMARK    GeneRIF: Dscam is highly expressed in rat brain during the
            different phases of experimental epilepsy.
REFERENCE   3  (bases 1 to 6656)
  AUTHORS   Fuerst,P.G., Bruce,F., Tian,M., Wei,W., Elstrott,J., Feller,M.B.,
            Erskine,L., Singer,J.H. and Burgess,R.W.
  TITLE     DSCAM and DSCAML1 function in self-avoidance in multiple cell types
            in the developing mouse retina
  JOURNAL   Neuron 64 (4), 484-497 (2009)
   PUBMED   19945391
REFERENCE   4  (bases 1 to 6656)
  AUTHORS   Wang,M.C., Jia,Y.J., Wen,Q.Q., Guan,W.J., Zhao,E.Y., Wang,L.D. and
            Zhang,B.A.
  TITLE     [Effects of DSCAM on differentiation of rat marrow mesenchymal stem
            cells into neurons in vitro]
  JOURNAL   Zhongguo Dang Dai Er Ke Za Zhi 11 (6), 486-489 (2009)
   PUBMED   19558816
  REMARK    GeneRIF: DSCAM may play an important role in mesenchymal stem cells
            (MSCs) differentiation into neural cells.
REFERENCE   5  (bases 1 to 6656)
  AUTHORS   Liu,G., Li,W., Wang,L., Kar,A., Guan,K.L., Rao,Y. and Wu,J.Y.
  TITLE     DSCAM functions as a netrin receptor in commissural axon
            pathfinding
  JOURNAL   Proc Natl Acad Sci U S A 106 (8), 2951-2956 (2009)
   PUBMED   19196994
REFERENCE   6  (bases 1 to 6656)
  AUTHORS   Ly,A., Nikolaev,A., Suresh,G., Zheng,Y., Tessier-Lavigne,M. and
            Stein,E.
  TITLE     DSCAM is a netrin receptor that collaborates with DCC in mediating
            turning responses to netrin-1
  JOURNAL   Cell 133 (7), 1241-1254 (2008)
   PUBMED   18585357
REFERENCE   7  (bases 1 to 6656)
  AUTHORS   Fuerst,P.G., Koizumi,A., Masland,R.H. and Burgess,R.W.
  TITLE     Neurite arborization and mosaic spacing in the mouse retina require
            DSCAM
  JOURNAL   Nature 451 (7177), 470-474 (2008)
   PUBMED   18216855
REFERENCE   8  (bases 1 to 6656)
  AUTHORS   Barlow,G.M., Chen,X.N., Shi,Z.Y., Lyons,G.E., Kurnit,D.M.,
            Celle,L., Spinner,N.B., Zackai,E., Pettenati,M.J., Van Riper,A.J.,
            Vekemans,M.J., Mjaatvedt,C.H. and Korenberg,J.R.
  TITLE     Down syndrome congenital heart disease: a narrowed region and a
            candidate gene
  JOURNAL   Genet Med 3 (2), 91-101 (2001)
   PUBMED   11280955
REFERENCE   9  (bases 1 to 6656)
  AUTHORS   Barlow,G.M., Micales,B., Lyons,G.E. and Korenberg,J.R.
  TITLE     Down syndrome cell adhesion molecule is conserved in mouse and
            highly expressed in the adult mouse brain
  JOURNAL   Cytogenet Cell Genet 94 (3-4), 155-162 (2001)
   PUBMED   11856873
REFERENCE   10 (bases 1 to 6656)
  AUTHORS   Yamakawa,K., Huot,Y.K., Haendelt,M.A., Hubert,R., Chen,X.N.,
            Lyons,G.E. and Korenberg,J.R.
  TITLE     DSCAM: a novel member of the immunoglobulin superfamily maps in a
            Down syndrome region and is involved in the development of the
            nervous system
  JOURNAL   Hum Mol Genet 7 (2), 227-237 (1998)
   PUBMED   9426258
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF334385.1.
            
            On Dec 17, 2003 this sequence version replaced XM_346413.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF334385.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760384 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..6656
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..6656
                     /gene="Dscam"
                     /note="DS cell adhesion molecule"
                     /db_xref="GeneID:171119"
                     /db_xref="RGD:619992"
     exon            1..519
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     CDS             477..6518
                     /gene="Dscam"
                     /note="Down syndrome cell adhesion molecule homolog; cell
                     adhesion molecule DSCAM"
                     /codon_start=1
                     /product="cell adhesion molecule DSCAM precursor"
                     /protein_id="NP_598271.1"
                     /db_xref="GeneID:171119"
                     /db_xref="RGD:619992"
                     /translation="MWILALSLFQSFANVFSEEPHSSLYFVNASLQEVVFASTSGTLV
                     PCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYC
                     TAENPSGKIRSQDVHIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYVTVVSW
                     EKDTVSLVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVS
                     DPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVT
                     GLLIENSRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLS
                     CSVTGNEDQELSWYRNGEILNPGKNVRITGLNHANLIMDHMVKSDGGAYQCFVRKDKL
                     SAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLVCNVKGTPLPTVTWTLDDDPILKG
                     SGHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIR
                     PMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNANLLPFNHRQVAFENNGTLKLSDVQK
                     EVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDL
                     PITITWQKDGRPIPASLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQS
                     QLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALN
                     GRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTL
                     ATQGQRKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTV
                     REDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFDGNSP
                     ITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPS
                     NEITITADEAAPDGPPQEVHLEPTSSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTG
                     GNFQFNIISIDTTGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVP
                     SYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLIDGELGEIKNVTTT
                     QPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASM
                     VFVSWLPPLKLNGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVV
                     AVTSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWM
                     KDSNGTPSLVTIDGRRSIFSNGSFVIRTVKAEDSGYYSCVANNNWGSDEIILNLQVQV
                     PPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSY
                     RLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRL
                     NLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQMRVCN
                     SAGCAEKQANFATLNYDGSTIPPLIKSVVQSEEGLTTNEGLKILVTISCILVGVLLLF
                     VLLLVVRRRRREQRLKRLRDAKSLAEMLMSKNTRTSDTLSKQQQTLRMHIDIPRAQLL
                     IEERDTMETIDDRSTVLLTDADFGEAAKQKSLTVTHTVHYQSVSQATGPLVDVSDARP
                     GTNPTTRRNAKAGPTARNRYASQWTLNRPHPTISAHTLTTDWRLPTPRATGSVDKESD
                     SYSVSPSQDTDRARSSMVSTESASSTYEELARAYEHAKMEEQLRHAKFTITECFISDT
                     SSEQLTAGTNEYTDSLTSSTPSESGICRFTASPPKPQDGGRVVNMAVPKAHRPGDLIH
                     LPPYLRMDFLLNRGAPGTSRDLSLGQACLEPQKSRTLKRPTVLEPTPMEASSSTSSTR
                     EGQQSWQQGAVATLPQREGAELGQAAKMSSSQESLLDSRGHLKGNNPYAKSYTLV"
     exon            520..837
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            838..984
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1131
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1410
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            1411..1686
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..1983
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            1984..2259
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            2260..2538
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            2539..2658
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            2659..2832
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            2833..3029
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            3030..3126
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            3127..3255
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            3256..3423
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            3424..3494
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            3495..3735
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            3736..3882
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            3883..4038
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            4039..4172
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            4173..4326
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            4327..4444
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            4445..4608
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            4609..4707
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            4708..4896
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            4897..5187
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            5188..5364
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            5365..5395
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            5396..5511
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            5512..5661
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            5662..5859
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            5860..6162
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
     exon            6163..6644
                     /gene="Dscam"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcggcccg ccgggctcag gcagggaagg gcagcacagg ggacccggcg cccgaggccg
       61 ccgcagcagg atgagcctgg ccgcgcgcct gctgcctggc tgcggagggt gaggccggcg
      121 cccgggaggc cgccgcctgg ccgcgctgcg catcgggggg cgcccggcat gagctcgcgc
      181 ccgcggctgc ggctgtgcgc ccgcgcctgg ctgcccgcgg cccgctgagc cgagccgagc
      241 gcacggcgca cctgggctgt gtccgcggcg cggggcgcgg cgcccgggag caggtgtgcg
      301 ggggcgcagc aagcggggag cgcggctggg cggctgggcg gcccccgggc aggtggcggg
      361 cggcgagcgg agccgggccg ggcgcggcgg agcgcagcgc agcgcggggg gcgaggccgg
      421 cgcgtggctc gctcgctggc tcgctggctc gcgggaggcc gggcagcagc aggggcatgt
      481 ggatactggc tctctccttg ttccagagct tcgcgaatgt tttcagtgaa gagccccact
      541 ccagcctcta ctttgtcaat gcatcgctgc aagaggtagt gtttgcaagc acgtcgggga
      601 ccctggtgcc ctgcccggct gcaggcatcc ctcctgtgac tctcagatgg tacctagcaa
      661 cgggcgagga gatctacgat gtccctggga tccgccacgt ccatcccaat ggcactctcc
      721 aaattttccc ctttcctcct tcaagcttca gcaccttaat ccatgataat acttactatt
      781 gcacagctga aaacccttca gggaaaatta gaagtcagga tgtccacatc aaggctgttt
      841 tacgggagcc ctatacagtc cgtgtggagg accagaaaac catgagaggc aatgtcgcgg
      901 tgttcaagtg cattatcccc tcctcggtgg aggcgtacgt cactgtcgtc tcatgggaga
      961 aagacacggt ttcacttgtc tcaggatcta gatttctcat cacatccacg ggagccttgt
     1021 atattaaaga tgtacagaac gaagatgggc tgtacaacta ccgctgcatc acgcggcaca
     1081 gatacacagg ggagacgaga caaagcaaca gcgcgagact gttcgtgtca gacccagcga
     1141 actcagcccc atccatcctg gacgggtttg accaccgcaa agccatggca gggcagcgtg
     1201 tggagctgcc gtgcaaagct cttgggcacc ccgagccgga ctaccgctgg ctgaaagata
     1261 acatgcccct ggaactttcc ggaaggttcc aaaagacagt gaccgggctg ctcattgaga
     1321 acagccgccc ttcagactca ggcagctacg tgtgtgaagt atccaaccga tacggcactg
     1381 ccaaggtgat aggccgcctg tacgtgaaac agccactgaa agccaccatc agtcccagaa
     1441 aggttaaaag cagtgtgggc agccaggtct ccttgtcctg cagtgtgaca ggaaacgaag
     1501 accaggagct ctcctggtac agaaatggtg aaatcctcaa ccctgggaaa aacgtgagga
     1561 tcacaggact caaccacgcg aaccttataa tggatcacat ggtcaagagt gatgggggcg
     1621 cctaccagtg ctttgttcgc aaggacaagc tatctgctca agactatgtc caggtggtcc
     1681 ttgaagacgg aactcccaaa atcatttccg cctttagcga gaaagtggtg agcccggcag
     1741 agccagtgtc cctcgtgtgt aatgtgaagg gtacaccctt gcccacggtc acctggaccc
     1801 tggacgatga ccccatcctc aagggcagcg gccaccgcat cagccaaatg atcacgtccg
     1861 aggggaacgt ggtcagctac ctgaatatct ccagctccca ggtccgggat gggggtgtct
     1921 accgctgcac tgccaacaac tcggctggag tcgtcctgta ccaggctcga ataaacgtaa
     1981 gagggccggc aagcatcaga ccgatgaaaa acatcactgc gatagcaggg cgtgacacgt
     2041 acatccactg ccgtgtgatt ggctaccctt attactccat caagtggtac aagaacgcta
     2101 acctgcttcc tttcaaccac cgccaggtgg cgtttgagaa caatgggact ctgaaactct
     2161 cagatgtgca gaaagaagtt gacgagggag agtacacatg taacgtgctg gtgcagccac
     2221 agctctccac cagccagagt gtccacgtga cagtcaaagt tcctcctttt atccaaccct
     2281 ttgagttccc aagattctct atcggtcagc gggtcttcat cccatgtgtg gtggtctcgg
     2341 gggacttacc catcaccatc acctggcaga aggatggccg gccgattcca gcaagcctcg
     2401 gtgtaaccat cgacaacatc gacttcacca gctccctgag gatctccaac ctctcactga
     2461 tgcacaacgg gaattacacc tgcatcgcgc ggaacgaggc ggccgccgtg gaacaccaga
     2521 gccagctgat tgtaagagtt ccccctaagt tcgtggtcca gccccgggac caggatggga
     2581 tctatggcaa agcagtgatt ctcaattgct ctgcagaggg ttatcctgtg cctacaattg
     2641 tgtggaaatt ctcaaaaggt gctggggtcc cccagttcca gccaattgcc ctgaatggca
     2701 gaatccaggt cctgagtaat ggctcactct tgatcaagca tgttgtggaa gaagacagtg
     2761 gctactacct ctgcaaggtc agcaacgatg tgggcgcaga cgtcagcaag tccatgtacc
     2821 tcacggtgaa aattcctgcc atgataacct cttatcccaa caccaccctg gccactcagg
     2881 gtcaaaggaa ggagatgagc tgcacagcac acggggagaa gcccatcatt gtccgctggg
     2941 agaaagagga caggatcatt aaccctgaaa tggcccgtta cctggtgtcc accaaggagg
     3001 tgggagagga agtgatttct actctgcaga ttttgccaac agtgagagaa gattccggct
     3061 tcttctcctg ccatgctatc aattcatatg gggaggaccg cggaataatt cagctcacgg
     3121 tgcaagaacc cccagacccc cccgagattg agatcaaaga tgtcaaagcc cgcacaatca
     3181 cgctcaggtg gaccatgggg tttgatggca acagccccat cacaggctac gacattgagt
     3241 gcaaaaataa atcagactcc tgggattctg ctcaaagaac caaagatgtt tcccctcagc
     3301 tgaactcggc caccatcatt gatatccacc cttcctccac ctacagcatc cgcatgtacg
     3361 ccaagaaccg gattggcaag agtgagccca gcaacgagat caccatcacg gcagatgagg
     3421 cagctcctga tggtccacct caggaagtgc acctggaacc cacctcatct cagagtatca
     3481 gggttacctg gaaggctccc aagaaacatt tacaaaatgg gatcatacgt ggctaccaga
     3541 taggctaccg ggagtacagc accgggggca acttccagtt caacatcatc agtatcgaca
     3601 ccaccgggga cagcgaagtg tacaccctgg acaacctgaa taagttcacc cagtatggcc
     3661 tagtagtaca ggcctgcaac cgggccggca cgggaccttc ttctcaggag ataatcacta
     3721 ccaccctgga ggacgtaccc agctaccctc ccgaaaatgt ccaagccata gcaacctcac
     3781 cagaaagcat atcaatctcc tggtccacgc tgtccaagga ggccttgaat gggattctcc
     3841 aggggttcag ggtcatctac tgggccaacc tcatagacgg agagctgggc gagattaaga
     3901 acgtcaccac cacgcagcct tccttggagt tggatggact agagaaatac accaactaca
     3961 gtatccaggt gctggccttc acccgtgcag gggacggcgt ccggagtgag cagatcttta
     4021 cccgtaccaa ggaggatgtt ccaggtcctc ctgctggtgt caaggcagca gcagcctcgg
     4081 cctccatggt ctttgtgtcc tggctgcccc cgctcaagct gaatggcatc attcggaagt
     4141 acacggtgtt ctgctcccac ccctacccca cagtcatcag cgagtttgaa gcctcccctg
     4201 actcattttc ctacagaatt cctaacctga gtcggaatcg acagtatagc gtctgggtgg
     4261 tggcagtgac ttccgccgga agaggcaaca gcagtgagat catcaccgtg gagcctctgg
     4321 ctaaagctcc tgcacggatc ctcacgttca gtgggacagt gactactccg tggatgaagg
     4381 acatcgtctt gccgtgtaaa gctgttggag acccatcacc tgccgtaaaa tggatgaagg
     4441 atagtaacgg gacgcccagc ctggtgacga ttgatggccg cagaagcatc ttcagcaatg
     4501 ggagtttcgt tattcgcacg gtgaaggccg aggactctgg ctactacagc tgtgttgcca
     4561 ataacaactg gggatcagat gagatcatat taaatttgca agtacaagtt ccaccagatc
     4621 agcctcggct caccgtatcc aagacgacat cctcctccat caccctttcc tggcttcctg
     4681 gagacaatgg gggcagctcc atcagaggct acatcctgca atattccgag gacaacagtg
     4741 agcagtgggg gagctttccc atcagcccca gcgagcgttc ctaccgcttg gaaaacctaa
     4801 agtgtgggac atggtataag ttcaccctta ctgcccaaaa tggagtggga cccggacgca
     4861 taagtgaaat catagaagcc aaaactctgg ggaaagaacc ccagttctcc aaggagcagg
     4921 agctcttcgc cagcatcaat accacccgag tgaggctgaa tctgattggc tggaacgacg
     4981 gcggctgtcc aatcacctca ttcactcttg agtacagacc cttcgggacc acggtctgga
     5041 ccacagctca gcggacctcc ctttccaagt cttacattct gtatgacctc caagaagcca
     5101 catggtatga actgcagatg cgagtgtgca acagcgccgg ctgcgcagag aagcaagcca
     5161 actttgccac gctgaactac gatggcagta caatccctcc actcattaag tcagttgtcc
     5221 aaagcgaaga agggctgaca accaacgaag ggctcaagat cctcgtgacc atctcctgca
     5281 tcctggtcgg ggttctgctg ctctttgtgc ttctgctggt ggtgcgaagg agacggaggg
     5341 agcagaggct gaagaggctg agagatgcaa agagtttagc tgagatgctc atgagcaaga
     5401 acacacggac ttcagatacc ttgagcaaac agcaacagac tctgaggatg cacattgata
     5461 tacccagggc tcagcttttg attgaagaga gagacacaat ggagaccata gatgaccgct
     5521 ccacagtcct gttaacggat gctgactttg gggaggcagc caaacagaag tcactgacgg
     5581 tgactcacac ggtgcattac caatcggtgt ctcaggccac cgggccccta gtggatgtct
     5641 ccgatgctcg gccaggaacg aatcccacca ccaggaggaa tgcaaaggct ggacccacag
     5701 caagaaaccg gtacgccagc cagtggaccc tcaacagacc ccaccccacc atctcagcac
     5761 acactctcac cacagactgg agactgccta cccccagggc tacaggctcc gtggacaagg
     5821 aaagtgacag ctacagcgtc agcccatcac aagacacaga cagagcaagg agcagcatgg
     5881 tctccacaga aagtgcctcc tctacctacg aagaactggc cagggcctac gagcacgcca
     5941 agatggagga gcagctgagg cacgccaagt tcaccatcac agagtgcttc atatccgaca
     6001 cgtcctccga gcagctgacg gcagggacaa acgagtacac ggacagtctg acctccagta
     6061 ccccttcaga atcggggatc tgcagattca ctgcgtctcc ccccaaacct caggatggag
     6121 gtcgtgtggt gaacatggcg gttccaaagg cccatcggcc aggcgacctc atacacctgc
     6181 ctccatacct gcgaatggac ttcttgttaa accggggcgc accaggcacc agcagggacc
     6241 tgagcttagg acaagcgtgc ttggaacccc agaaaagtcg gaccctgaag cgccccacgg
     6301 tccttgagcc cacccctatg gaggcttcct cctccacctc ttccacgaga gaaggacagc
     6361 agtcgtggca acaaggggcc gtggccacct tacctcagcg agagggtgca gagctgggac
     6421 aggcagctaa aatgagcagc tcccaagagt cgctgctgga ctctcggggc cacttgaaag
     6481 gaaacaatcc ctacgcaaaa tcctacacct tggtataaca catggcgcgg ctggacagcg
     6541 gttgtaaata caatttaaac gatccaatca aagctacctt ttttttacgg aattccaata
     6601 tttataatta aagaaaattg ccaaaatata ttaaaaaaaa aaaaaaaaaa aaaaaa
//
