LOCUS       NM_001107402            2878 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus desmocollin 3 (Dsc3), mRNA.
ACCESSION   NM_001107402 XM_001053804 XM_226122
VERSION     NM_001107402.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2878)
  AUTHORS   Xu,X., Dong,C. and Vogel,B.E.
  TITLE     Hemicentins assemble on diverse epithelia in the mouse
  JOURNAL   J Histochem Cytochem 55 (2), 119-126 (2007)
   PUBMED   17015624
REFERENCE   2  (bases 1 to 2878)
  AUTHORS   Den,Z., Cheng,X., Merched-Sauvage,M. and Koch,P.J.
  TITLE     Desmocollin 3 is required for pre-implantation development of the
            mouse embryo
  JOURNAL   J Cell Sci 119 (Pt 3), 482-489 (2006)
   PUBMED   16418220
REFERENCE   3  (bases 1 to 2878)
  AUTHORS   Cheng,X., Mihindukulasuriya,K., Den,Z., Kowalczyk,A.P.,
            Calkins,C.C., Ishiko,A., Shimizu,A. and Koch,P.J.
  TITLE     Assessment of splice variant-specific functions of desmocollin 1 in
            the skin
  JOURNAL   Mol Cell Biol 24 (1), 154-163 (2004)
   PUBMED   14673151
REFERENCE   4  (bases 1 to 2878)
  AUTHORS   Kowalczyk,A.P., Palka,H.L., Luu,H.H., Nilles,L.A., Anderson,J.E.,
            Wheelock,M.J. and Green,K.J.
  TITLE     Posttranslational regulation of plakoglobin expression. Influence
            of the desmosomal cadherins on plakoglobin metabolic stability
  JOURNAL   J Biol Chem 269 (49), 31214-31223 (1994)
   PUBMED   7983064
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473974.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_226122.4, XM_001053804.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760400, SAMEA5760434
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2878
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..2878
                     /gene="Dsc3"
                     /note="desmocollin 3"
                     /db_xref="GeneID:307563"
                     /db_xref="RGD:1311782"
     exon            1..256
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     CDS             176..2878
                     /gene="Dsc3"
                     /codon_start=1
                     /product="desmocollin-3"
                     /protein_id="NP_001100872.1"
                     /db_xref="GeneID:307563"
                     /db_xref="RGD:1311782"
                     /translation="MAMAMAVPELRSLPYRAPFTKFLLTLWVFSFVGEACKDVTFYVP
                     STLEADKIIGRVSLKECLSSADGIMPSDPDFRVLDDGSVYPTRAVVLSDEKRSFTIQL
                     SDSKMRKQKEITVILERQKEVMMKRHTNETVLRRAKRRWAPIPCSMQENSLGPFPLFL
                     QQVQSDSAQNYNIFYSISGRGVDQEPLNLFFIERDTGNLYCTRPVDREEYDVFDLIAY
                     ASTADGYSADLPLPLPIKVEDENDNYPLFTEAIYNFEVPESSRLGTVVGTVCATDKDE
                     PDTMHTRLKYSILEQSPPSPGLFSVHPDTGVITTVSHYMDREVVDKYKLILKVQDMNG
                     QFFGLISTSTCIITVQDSNDNAPTFRQNAYETSVEENTYNVEILRIPVDDKDMVNSAN
                     WKANFTILKGNENGWFKITTDPATNEGVLCVVKPLDYEENRQVTLEIGVNNEAPFIRD
                     VASRIPTMNRAMVTVQVRDQNEGPECKPREQIVRIKENSAIGSKINGYKAYDPETKNS
                     NGLRYKKLQDPKDWVSIEEVSGSLTISKILDREIMAPRNDLYNITVMAIDQEGRSCTG
                     TLAVNIEDMNDNAPEIIQDDIVICKPRMGYTDISAVDPDEPIHGPPFQFALASSSPEV
                     NRIWTLNQVNDTAARLSYQKTADVQIYSVPVTVTDRAGQSATKILRVNLCDCTHPSQC
                     LLRSRRAGITLGKWAILAILLGIALLFSVLLTLVCGVVTAQKGKHFPEDLAQQNLIIS
                     NTEAPGDDRVCSANGFTTHTANNSSQGFCGTMGSGMRNGGQETIEMMKGHQTLDSCRV
                     AGHHHTLDSCRGGHMETDNCRYTYSEWHSFTQPRLGEKLHVCNQNEDHIPSQDYVLTY
                     NYEGRGSPAGSVGCCSEKQEEEGLDFLNNLEPKFLTLAETCTKR"
     exon            257..341
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            342..541
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            542..661
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            662..817
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            818..962
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1129
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1264
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1450
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1710
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1711..1853
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1854..2078
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2079..2303
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2304..2425
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2426..2680
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2681..2878
                     /gene="Dsc3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actgagcgtc tccttagtcc aatccagttt caggcgagaa catgcttcta ggcaaagaag
       61 cttgagagag gccagaacaa cttctagaca agctgctgtg gaaaacctcc tgtgccctgg
      121 ctcttagagt ccttacttgg tgcccgcctg cgtcctcctg aggcagcacc gaacgatggc
      181 gatggcgatg gcggtccctg agctccggag cctgccgtac agggcaccat tcacgaagtt
      241 cctgctgacc ctctgggtct tcagttttgt tggtgaagcc tgtaaagatg tgacctttta
      301 tgtaccttca acactagagg cagacaagat catcggaaga gttagtttga aggagtgtct
      361 cagctcggct gatggtatca tgccaagcga tcctgacttc agagttctag atgacgggtc
      421 agtttatcct accagagctg ttgtgttgtc tgatgagaaa agatcattta ccattcagct
      481 ttctgattca aagatgcgga aacagaaaga gatcactgta atcctggagc gccagaagga
      541 ggtaatgatg aaaagacaca ctaatgaaac tgtcctcaga agagccaaga ggagatgggc
      601 acccattccg tgttcaatgc aagaaaattc cttgggtccc ttcccattgt ttcttcaaca
      661 ggttcagtct gattcagctc agaactacaa tatcttctac tcaataagcg ggcgtggagt
      721 tgaccaagaa ccactgaatt tgtttttcat tgagagagac actgggaatc tttattgtac
      781 tcggcctgtg gatcgtgaag aatatgatgt ttttgatttg attgcctatg catccactgc
      841 agatggctac tcagcagatt tacctctccc cctgcccatc aaagtagagg atgaaaatga
      901 caattaccct ctttttacag aagcaattta caattttgaa gttccagaaa gcagtagact
      961 tggtaccgtg gtgggaacgg tgtgtgctac ggacaaagat gaacccgata cgatgcacac
     1021 gcgcctcaag tacagcatct tggagcagag tccgccgtcc ccagggctct tttctgtgca
     1081 ccctgacacc ggcgtcatca ccactgtctc tcactacatg gacagagagg ttgtagacaa
     1141 gtacaaactg atcttgaaag tccaggacat gaatggccaa ttctttggac tcatcagcac
     1201 atcaacttgt atcataacag tgcaagattc caatgacaat gctcccacat tcagacaaaa
     1261 tgcttatgaa acttctgtgg aggaaaatac atataatgtt gagatcttgc gcatacctgt
     1321 agatgataag gacatggtta acagtgccaa ctggaaggca aatttcacca tcttaaaagg
     1381 aaatgaaaac ggctggttca aaatcacgac agacccagcg acaaatgagg gtgttctgtg
     1441 tgtcgtgaag ccactggatt atgaagaaaa tcgtcaagtg accctagaga tcggtgtgaa
     1501 caacgaagct ccattcatta gagatgttgc aagccgaata cccaccatga atcgggccat
     1561 ggttacagtc caagtgaggg atcagaatga ggggccggaa tgcaagcccc gtgagcagat
     1621 tgtacggatc aaagagaact cagcaattgg gtctaagatc aatggctaca aggcctatga
     1681 ccccgaaacc aagaatagca atggtttaag gtacaaaaaa ttgcaggatc ctaaagactg
     1741 ggtcagcatt gaagaagttt caggatcact caccatatca aaaatcctgg acagagaaat
     1801 catggctcca agaaatgacc tatacaatat tacagtcatg gcaattgacc aagagggtag
     1861 atcatgcaca gggacgcttg cagtgaacat tgaggatatg aatgacaacg caccagagat
     1921 aattcaagat gacattgtca tctgcaagcc aaggatgggt tatacagaca tttcagctgt
     1981 ggatcctgat gaacctattc acggccctcc cttccagttc gccttggcaa gctcttctcc
     2041 agaagtcaac agaatctgga ccctcaacca agttaatgat acagctgccc gcctgtccta
     2101 tcagaaaacc gcggatgttc agatatactc cgttcctgta actgtaacag acagagcagg
     2161 ccaatctgcg accaagatct tgagagttaa cctgtgcgat tgtactcacc ccagccagtg
     2221 tctgctcaga tcaagaagag cggggatcac cctggggaag tgggcaatcc ttgccatctt
     2281 gctgggcatc gctctgctat tctcggtact gctaacttta gtatgtgggg ttgttactgc
     2341 tcaaaaagga aaacattttc ctgaagattt agcacagcaa aacttaatta tatcaaatac
     2401 cgaagcaccc ggggacgaca gagtgtgctc tgccaatgga ttcaccaccc acactgccaa
     2461 caactccagc caaggcttct gtggcacaat ggggtcagga atgaggaacg gtgggcagga
     2521 gaccatcgag atgatgaaag gccaccagac cttggactcc tgccgtgttg ctgggcatca
     2581 ccacaccctg gactcctgca ggggaggaca catggaaacc gacaactgca gatacacgta
     2641 ctcagagtgg cacagcttca ctcagccccg actcggcgaa aaattgcatg tgtgtaatca
     2701 gaacgaagac cacatcccat ctcaagacta tgtcctcacc tataactacg aaggcagggg
     2761 atctccagcc ggttctgtag gttgctgcag tgaaaagcag gaagaagagg gactcgactt
     2821 tttaaacaat ttggagccca aatttcttac attggcagaa acatgtacaa agagataa
//
