LOCUS       XM_008771992            6277 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus desmocollin 1 (Dsc1), transcript
            variant X4, mRNA.
ACCESSION   XM_008771992
VERSION     XM_008771992.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051353.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 25, 2024 this sequence was replaced by
            NM_001106161.2.
            
            On Jan 21, 2021 this sequence version replaced XM_008771992.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6277
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6277
                     /gene="Dsc1"
                     /note="desmocollin 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 4 ESTs, 2 Proteins, and
                     99% coverage of the annotated genomic feature by RNAseq
                     alignments"
                     /db_xref="GeneID:291759"
                     /db_xref="RGD:1310768"
     CDS             753..3443
                     /gene="Dsc1"
                     /codon_start=1
                     /product="desmocollin-1 isoform X3"
                     /protein_id="XP_008770214.2"
                     /db_xref="GeneID:291759"
                     /db_xref="RGD:1310768"
                     /translation="MAAACAAPGSTFSKQLLFLLLVLVLLCNACQKVSLQVPSHLKAE
                     KPIGKVNLEECLKSPSLILSSDPAFRILEDGTIYATHDLLLSSEKRGFSILLSDSQGQ
                     EQKKLEIVLSAREKKAFRKRHTKEPVHKRSKRRWAPIPCSLMENSLGPFPQHVQRIQS
                     DFSQNYSIFYSISGPGVDKEPFNLFYIEKDTGDIYCTRSIDREEYDQFMVYGYATTAD
                     GYAPEYPLPLLFKVEDDNDNAPYFETKLTVFSVPENCRYGTSVGQVTAIDKDEPGTLH
                     TRLKYKILQQIPDHPKHFTVHPDTGVITTTTPLLDREKCDTYKLVMEVRDMGGQPFGL
                     FTTGTITISLEDENDNSPCFTQSSYFAEVDENRIDVEILRMMVQDQDLPNTPHSKAVY
                     KILQGNENGNFKITTDPNTNEGVLCVVKPLNYEVSRQVTLQISVLNEAQFTNAANTQP
                     PTMCTATVTVKIKDRDEGPECLPPVKVIQSKDGLPAGQQLLGYKAMDPETSSGEGLRY
                     KMVGDEDNWFEINESTGDLRTVKVLDRESKFVKNNQYNISVVAMDSVGRSCTGTLVVL
                     LEDFNDHPPQIDKDITICQQEKDYAVLEPVDLDGPDNGPPFQFLLDNSSSKLWTLESQ
                     DGKRAILRQRHNLNYNYYSVPIQIQDRHGFSAKHVLSVRVCDCTIPSECRMAIEERDV
                     KPNVILGKWAILAMVLGSALLLCILFTCFCVTTTKRTVKKCFPDDVAQQNLIVSNTEG
                     PGEEVTEANIRLPTQTVNICDTSTSVGTLGGQGIKTQQNFEMVKGGYTLESNKGGGHH
                     TLESSKGGVLGAADTGRYAYTDWQTFTQPRLGEKVYLCGQAEEHKHCDDYVRSYNYEG
                     KGSMAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCVKK"
ORIGIN      
        1 tctagagaac tgactcctag gagacagaaa ataatagggg acagacacaa tgcacctgtg
       61 gcatccactg gaatgtaatc tctctggcaa agctgtagtg cttcgtggct taggctatcc
      121 ctgaatgctt tgatgagaag ataactccag atggaaatga ttgcacaagc tctgccctct
      181 gatttgccaa tgtgcctgac caggaattcc ttttctttac tttttttttt tttttttgca
      241 taggctttat gcacaattcc tgtttgcacc cagggggcaa ggcaggttat taaggccaag
      301 aaggagggaa ggctgtggga ggacataata actgggagga cttcacagcc tctacctggg
      361 ggtaaaggga ggagggctga gcatggaggg tgttgtcttt taattctgac tatgtgttga
      421 gtggcaggag aaattttgaa agctgctttg aggaggagcc agtgcctggg catggagtgt
      481 tctgtgcccc gctctcccca cttgtaggaa accttctctc catgcacaag taattggact
      541 ggaaggagta cgactggcaa aggaaaagag ccattctgtc tcctcctcct gttccttatc
      601 tctcacatcc tgactttctt ccaaagccgc ctcagctgtg ccaagctggc tgcagagcgt
      661 cttgacaggt gccagcatct gcttagcctc cctgtgcact ccaggcctct ctattagctg
      721 ctcaccgtcc ctggccattg ggaccgcttc agatggctgc ggcctgtgct gccccaggga
      781 gcaccttctc taagcagctc cttttccttc tcctggttct ggtattactt tgcaatgcgt
      841 gtcagaaagt ttcccttcaa gttccctctc atcttaaggc cgaaaaacct ataggcaaag
      901 tgaatctgga ggagtgtctc aaatcaccca gcctgatcct gtccagtgac ccagccttca
      961 gaattctaga agacggcaca atttatgcaa cacacgacct gcttttgtct tctgaaaaga
     1021 ggggtttctc catcttgctc tcagacagtc aagggcagga acaaaagaag ctagaaattg
     1081 tactgtcagc aagagaaaaa aaggctttta ggaagaggca taccaaggaa ccagtgcaca
     1141 agcgcagtaa gagaagatgg gctcccattc cgtgttcact gatggagaac tcactgggtc
     1201 catttccaca gcacgttcag aggatccaat ctgattttag ccagaattat tccatctttt
     1261 actctatcag cggaccaggt gtggacaaag agcctttcaa tttgttctac atcgagaaag
     1321 acactgggga catctattgt acccgaagca ttgaccgtga agagtatgac caatttatgg
     1381 tgtatggata tgcaaccact gctgatggct atgccccaga gtaccctctg cctctgctct
     1441 tcaaggtaga agatgacaat gacaatgccc catattttga aaccaaactg acagttttta
     1501 gtgtgcctga aaattgtcga tacggaactt cagtgggaca agtgactgcc atagacaagg
     1561 atgagccagg aaccctacac actcgtctga agtacaaaat cttgcaacaa atcccagatc
     1621 accccaagca cttcaccgtc cacccagaca cgggtgtgat cactaccacc acacctttac
     1681 tggacaggga gaaatgtgat acttacaaac tagtgatgga ggtacgagac atggggggcc
     1741 agcccttcgg tctcttcacc accggaacga tcaccatctc actggaggat gagaatgaca
     1801 attcaccgtg tttcacccaa agttcttatt ttgcagaagt agacgaaaac agaattgatg
     1861 ttgagattct aaggatgatg gtgcaagacc aagatttgcc caacaccccc cactcgaagg
     1921 cggtatacaa aatcctacag gggaacgaga atgggaactt caaaatcaca acagatccaa
     1981 acacaaatga aggagtcttg tgtgttgtca agccattgaa ctatgaagtc agccgccaag
     2041 tcactctgca aatcagcgtg cttaacgaag cccagttcac taatgccgcc aacacacaac
     2101 ccccaacaat gtgcaccgca accgtcactg tgaaaattaa agacagagat gagggtcctg
     2161 agtgcttgcc accagtcaaa gtcattcaga gcaaagatgg gctcccagct ggccaacagc
     2221 tcctgggcta caaagcgatg gacccagaaa caagcagtgg cgaaggctta aggtataaaa
     2281 tggtaggaga cgaagataac tggtttgaga ttaacgaaag cacaggagac ttgagaaccg
     2341 tgaaagttct agaccgagag tcgaagttcg tgaagaacaa ccagtacaat atttccgtgg
     2401 tggcgatgga ttcagttggc cgatcttgca caggaacact ggtagtcctt ctggaagatt
     2461 ttaatgacca cccaccacag attgacaagg acataaccat ttgtcagcag gaaaaggatt
     2521 atgccgtttt ggaacccgta gatctagatg ggccagataa tggtccacct ttccagttcc
     2581 ttctggataa ttcttccagc aaactttgga ctctagagtc acaggatggt aaacgtgcca
     2641 ttcttcggca acgacacaat cttaattata actactattc tgtgccaatc caaatacaag
     2701 acagacatgg tttttctgca aaacatgtat tatcagtgcg agtgtgtgac tgtacaattc
     2761 catcagaatg tagaatggcc attgaggaga gggatgttaa accaaatgta atccttggga
     2821 aatgggccat tctcgccatg gtcctgggat ctgcattgct actgtgcatt ttatttacat
     2881 gcttctgtgt gactactact aagagaacag tcaagaaatg cttcccagat gatgtagccc
     2941 agcaaaattt aattgtatca aacaccgaag gaccaggaga agaagtgacg gaggcaaata
     3001 ttagactccc cacacagaca gtcaacatct gtgatacaag cacatctgtt gggactcttg
     3061 gtggccaagg aatcaaaaca cagcaaaatt ttgagatggt caaaggaggc tacaccttgg
     3121 agtccaacaa aggaggtggc caccatacct tggagtccag caaaggaggt gtgctaggag
     3181 cagcagacac tggccgatat gcttacactg actggcaaac tttcactcaa cctcggctcg
     3241 gcgaaaaggt gtatttgtgt ggacaagctg aggaacacaa gcattgtgat gactacgttc
     3301 gctcatataa ctatgaaggc aaaggctcca tggctggttc tgtgggttgc tgcagtgatc
     3361 ggcaggagga agaagggcta gagtttttag atcacttgga accgaaattt aggacattag
     3421 caaagacatg tgtgaagaaa taaaggtgct agttagtaga gaaacatctg caaatgaaca
     3481 caggggtgtc actggatgta agaggataac agcttgtagt agcgactttg ggtattaaaa
     3541 gaaagtaaag tcatttgtag ataagggtgc tttaccaacc atagctcccc aaattctcct
     3601 tgtccccaga acttgcctgt tgtctagaca ggatgttgtc actgttgctt ttctttctgt
     3661 gcgtgtctat ggcctcttca ggactgaact gcgtgtgcca ctgaaattct ggtgatgtct
     3721 gaaacttaag ctcttttgca cactgtgcaa ggctccatgg tagagttggg tattgtggaa
     3781 gcttaaaata tgagtttgca ttgtgtatat aaaaagtaaa tatttttcaa ggtcatggga
     3841 attctgcttc taaagtattt cctttagtgc caagatattg tttttccctt ttccagagta
     3901 gcttcagata aacttttaag tgttttaggt atagcctttt gtgtgcctaa caagctctac
     3961 tctcactgta catttccctc attagaagag tgctatcttc attcagagcc ttcaaagctt
     4021 acgactcgat ctctgcccac atggctatgt tatcattggg atcatggagc ttctgtctga
     4081 ataacatggg tcagagcatc atgctcactg gacctaaaac tgtagagatt tgtcaagaat
     4141 tccatgaaaa tgaaaacact ggaatcctga tttctataaa ctagcttagg ctcacggaat
     4201 atatatatat atatatatat atatatatat atatatatat atatatatat cactgatcat
     4261 acttaatgtg gtactacctt accacattta tatgtactaa aatatgaaaa attatataaa
     4321 tactttggaa ggactgctag ctctttaact tgacactgat ctactatttc attggctttt
     4381 aactggtctc tgtctttaaa cttcactcca actagccata gaagcatcta gctgaaaccg
     4441 atacaaggct tagtccttac cgtatgttaa tactgagtta atgtccacat tgggacacaa
     4501 tactcagtat actttggtaa ttactcagag gaaaaaaagt tggaaggcta gaaataatgt
     4561 taagtggaca tgcattaaag atcattagtt cattacagga acatctacca aattttattg
     4621 aaacaatagc tattttaaca tgcatgaata aatgaggtgt aacactttaa taagattgtt
     4681 ttattgatct ataaagaaaa aaaatatatc taaattatat tttattagtc ctttgtggga
     4741 aagtacagat atgtgtcaag ttacacttca tgaaaactac atttaaacta aactttcctt
     4801 cttaacccat tactttctat ctattggcaa aatagtttgc tgtttcactt taggtcttat
     4861 tggtcttcat taggaaaggt gatttttatt gtgaaattgg atattggaat aaaatgaaat
     4921 atagcattag taaggcagat atgatctgta aattccccat aatgtgtgac ttttacagtc
     4981 actgtaagat gatttgggag ggggttgggg atttagctca gtggtagagc acttgcctag
     5041 caagcacaag gccctgggtt cggtccccag ctccgaaaaa aaaagaaaaa aaaagatgat
     5101 ttgggagtga tgcaattttt actttttgag gtaaatgtca tctgacaatg tgaattttga
     5161 cattttaggc tcttatatag taccaatttg gaaatgcgtc aaaggtcata gtaagttata
     5221 ttattcaatg tagttataga atattctatg agcagttgca aattattccc ttaacaatca
     5281 cttacagttg tttgtgtcat cttgctctta gacttactga attatacgtg agaaaacttt
     5341 tttctaaatt aaaccataca atttatatcc acaggtggat ttcttacgca tcaagagaag
     5401 gctctctaaa gcattagatg ttattagaaa gttcggagaa tttatctgta tcaagcagtt
     5461 ttagatattt aatttttttc aatatattat taaaactttt ctcagaggaa ttatatttat
     5521 ttttggattt atttaggcaa ctccaagtaa ttctcatttt tcatcaaaaa ttaaatatta
     5581 actgtatgat gaactaaata tatgaaaccc taccagactg caccatttag tttgctaata
     5641 aagtactgta tttcatataa atttgacttt taagtaattg ttgatttaat aaattgatag
     5701 ctatgaaatg ttttctgtat ttcaacatat atgggggaac atgcccagct tttatctttt
     5761 tgatgttggc ttcaaatatt tcatgagaga gacaaaatac ccatgggaag aaagatcagg
     5821 agagatgaaa tgatacagtt tctttagtga gcacgcttcc tcaaatgctc cctaacatac
     5881 taaatgttaa ttctcaatgt ttaaaaatac tgtatagaac ttgaaaccca tgtgtacatt
     5941 tactttgtag aaatgtcatt tggaaaatat ttaaatgagt gctttagatc tgggaagttt
     6001 ttcattccct ttttgtagta tgtaggtcat agaagtggtg tatgattgaa atctgaaatg
     6061 gaacgatagc catggaatat tatggcattg acccatttat tatctgcttc tcttataaat
     6121 ctaagggaac acagtaatca ctagacacca cctttgtttt tcctcttggg ggtaatggaa
     6181 aaagtacaga aggagaaagc tttctatgaa tacatagatt cacagtgtgt aaagcccaat
     6241 aaaataagtg aaaatacaat aaagattttc tggaata
//
