LOCUS       NM_001009685            1712 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus developmentally regulated GTP binding protein 1
            (Drg1), mRNA.
ACCESSION   NM_001009685 XM_223591
VERSION     NM_001009685.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1712)
  AUTHORS   Markolovic S, Zhuang Q, Wilkins SE, Eaton CD, Abboud MI, Katz MJ,
            McNeil HE, Lesniak RK, Hall C, Struwe WB, Konietzny R, Davis S,
            Yang M, Ge W, Benesch JLP, Kessler BM, Ratcliffe PJ, Cockman ME,
            Fischer R, Wappner P, Chowdhury R, Coleman ML and Schofield CJ.
  TITLE     The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of
            TRAFAC GTPases
  JOURNAL   Nat Chem Biol 14 (7), 688-695 (2018)
   PUBMED   29915238
  REMARK    Erratum:[Nat Chem Biol. 2018 Jun 27;:. PMID: 29950663]
REFERENCE   2  (bases 1 to 1712)
  AUTHORS   Schellhaus AK, Moreno-Andres D, Chugh M, Yokoyama H, Moschopoulou
            A, De S, Bono F, Hipp K, Schaffer E and Antonin W.
  TITLE     Developmentally Regulated GTP binding protein 1 (DRG1) controls
            microtubule dynamics
  JOURNAL   Sci Rep 7 (1), 9996 (2017)
   PUBMED   28855639
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1712)
  AUTHORS   Perez-Arellano I, Spinola-Amilibia M and Bravo J.
  TITLE     Human Drg1 is a potassium-dependent GTPase enhanced by Lerepo4
  JOURNAL   FEBS J 280 (15), 3647-3657 (2013)
   PUBMED   23711155
REFERENCE   4  (bases 1 to 1712)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 1712)
  AUTHORS   Ishikawa K, Akiyama T, Ito K, Semba K and Inoue J.
  TITLE     Independent stabilizations of polysomal Drg1/Dfrp1 complex and
            non-polysomal Drg2/Dfrp2 complex in mammalian cells
  JOURNAL   Biochem Biophys Res Commun 390 (3), 552-556 (2009)
   PUBMED   19819225
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088410.1.
            
            On Jan 13, 2005 this sequence version replaced XM_223591.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088410.1, SRR8487231.100179.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1712
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..1712
                     /gene="Drg1"
                     /note="developmentally regulated GTP binding protein 1"
                     /db_xref="GeneID:305470"
                     /db_xref="RGD:1304993"
     exon            1..91
                     /gene="Drg1"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..1153
                     /gene="Drg1"
                     /codon_start=1
                     /product="developmentally-regulated GTP-binding protein 1"
                     /protein_id="NP_001009685.1"
                     /db_xref="GeneID:305470"
                     /db_xref="RGD:1304993"
                     /translation="MSGTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELIT
                     PKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTV
                     PGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKI
                     IENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNAD
                     VTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRW
                     NFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFK
                     YALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK"
     exon            92..215
                     /gene="Drg1"
                     /inference="alignment:Splign:2.1.0"
     exon            216..391
                     /gene="Drg1"
                     /inference="alignment:Splign:2.1.0"
     exon            392..461
                     /gene="Drg1"
                     /inference="alignment:Splign:2.1.0"
     exon            462..631
                     /gene="Drg1"
                     /inference="alignment:Splign:2.1.0"
     exon            632..762
                     /gene="Drg1"
                     /inference="alignment:Splign:2.1.0"
     exon            763..930
                     /gene="Drg1"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1053
                     /gene="Drg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1607
                     /gene="Drg1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaggtctag ctagtgtgaa ggccggttcg gctttgagcc cctgccacca tgagtgggac
       61 cttagcgaag atcgcggaga tcgaagccga gatggctcgg actcaaaaga acaaagctac
      121 agcacatcac cttggactgc ttaaggctcg ccttgctaag cttcgaagag agcttatcac
      181 tccaaaaggt ggtggtggtg gtgggccagg agaaggtttt gatgtggcca agacaggcga
      241 tgctcgaatt gggtttgtgg gttttccctc tgtggggaag tcaactctgc taagtaactt
      301 agcaggagtg tattctgaag tggcagccta cgagttcact actttgacca cagtacctgg
      361 tgtcatcaga tacaaagggg ccaagatcca gctcctggat ctcccaggta tcattgaagg
      421 tgccaaggat gggaaaggta gaggtcgtca ggtcattgca gtggcccgaa cgtgtaattt
      481 gatcttgatt gttctggatg tcctaaaacc cttggggcac aagaagataa ttgaaaatga
      541 gttggaaggc tttgggattc gtttgaacag caaacccccc aacattggct ttaagaagaa
      601 agacaaggga ggcattaatc tcacagccac ttgtcctcag agtgaactag atgctgaaac
      661 ggtgaagagc attctggctg aatataaaat tcataatgct gatgtaactt tgcgtagtga
      721 tgccacagct gatgacctca tcgacgtggt tgaaggaaac agagtttata ttccctgtat
      781 ctatgtatta aataagattg atcagatctc cattgaggag ttggatatta tatataaggt
      841 gcctcactgt gtacccatct ctgctcatca ccgctggaat tttgatgacc ttttggagaa
      901 gatctgggac tatctgaaac tagtgagaat ttacactaaa cccaaaggcc agttaccaga
      961 ttacacgtct ccagtagtcc tgccttattc taggaccacg gtggaagatt tctgcatgaa
     1021 gattcacaaa aatctgatca aagaatttaa atatgctttg gtctggggtc tctctgtgaa
     1081 acataatcct cagaaagtgg gtaaagacca tacgttggaa gatgaagatg tcattcagat
     1141 cgtgaagaag tgaaatcctg atccggtctg ctggccgagc acagcagtgt tccttatgac
     1201 caagtacctt cctcagcccc ttctgtcttt ggcagcctct ggattgggat atagggatgg
     1261 agacttccaa ctgaaacacc actctttttt tttttttttc tttaaagata gggtctcatg
     1321 tatttcaggc tggctttgaa ctctttgctg ctgaggcttg ccttgaattc tttttttttt
     1381 ttttttcctt tttctttttt tcggagctgg ggactgaacc cagggccttg cgtttgctag
     1441 gcaagcgctc taccactgag ctaaatcccc aaccccttgc cttgaattct ttattcatca
     1501 gcctccatct caagtgctga tgctgtgcct gcaacacctc agcaacgtac cttccctact
     1561 ttggtgtcac tgtcattgag ctgtataaaa tcctggtggg cccattgaaa aaaaaaaaaa
     1621 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1681 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
