LOCUS       NM_001007009            2493 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus dynein regulatory complex subunit 1 (Drc1), mRNA.
ACCESSION   NM_001007009 XM_343030
VERSION     NM_001007009.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2493)
  AUTHORS   Stauber,M., Weidemann,M., Dittrich-Breiholz,O., Lobschat,K.,
            Alten,L., Mai,M., Beckers,A., Kracht,M. and Gossler,A.
  TITLE     Identification of FOXJ1 effectors during ciliogenesis in the foetal
            respiratory epithelium and embryonic left-right organiser of the
            mouse
  JOURNAL   Dev Biol 423 (2), 170-188 (2017)
   PUBMED   27914912
REFERENCE   2  (bases 1 to 2493)
  AUTHORS   Li,Y., Klena,N.T., Gabriel,G.C., Liu,X., Kim,A.J., Lemke,K.,
            Chen,Y., Chatterjee,B., Devine,W., Damerla,R.R., Chang,C., Yagi,H.,
            San Agustin,J.T., Thahir,M., Anderton,S., Lawhead,C., Vescovi,A.,
            Pratt,H., Morgan,J., Haynes,L., Smith,C.L., Eppig,J.T.,
            Reinholdt,L., Francis,R., Leatherbury,L., Ganapathiraju,M.K.,
            Tobita,K., Pazour,G.J. and Lo,C.W.
  TITLE     Global genetic analysis in mice unveils central role for cilia in
            congenital heart disease
  JOURNAL   Nature 521 (7553), 520-524 (2015)
   PUBMED   25807483
REFERENCE   3  (bases 1 to 2493)
  AUTHORS   Wirschell,M., Olbrich,H., Werner,C., Tritschler,D., Bower,R.,
            Sale,W.S., Loges,N.T., Pennekamp,P., Lindberg,S., Stenram,U.,
            Carlen,B., Horak,E., Kohler,G., Nurnberg,P., Nurnberg,G.,
            Porter,M.E. and Omran,H.
  TITLE     The nexin-dynein regulatory complex subunit DRC1 is essential for
            motile cilia function in algae and humans
  JOURNAL   Nat Genet 45 (3), 262-268 (2013)
   PUBMED   23354437
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083825.1.
            
            On Nov 22, 2004 this sequence version replaced XM_343030.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083825.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2493
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q14"
     gene            1..2493
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /note="dynein regulatory complex subunit 1"
                     /db_xref="GeneID:362712"
                     /db_xref="RGD:1359318"
     exon            1..200
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..2310
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /note="coiled-coil domain-containing protein 164;
                     coiled-coil domain containing 164; dynein regulatory
                     complex subunit 1 homolog"
                     /codon_start=1
                     /product="dynein regulatory complex protein 1"
                     /protein_id="NP_001007010.1"
                     /db_xref="GeneID:362712"
                     /db_xref="RGD:1359318"
                     /translation="MNPSGSIGVLEQNGEEHLAAPILGPSVNSDNPQERIQARRLRIA
                     ARQEARRREALGEYLDGKKESEEEQSKSYKQKEESRLKLTKLLLCGTELVTNIQVAAD
                     IREIHRRVEEEETKRQRLEKLENEVKTSQDKFDEITSKWEEGRQKRIPQELWEMLNNQ
                     QVHCAGLVEDKNKLISELQQELKIKDDQYVKDLKKQSEDITVLLERMEEQVKSVMKNF
                     RQELNYIEKAFESERQELLTTNKKKWERALQAHNAKELEYLINRMKRVEDYEKQLNRQ
                     RVWDCEEYNSIKIKLEQDVQILEQQLQQMKATYQLNQEKLEYNFQVLKKRDEESTVIK
                     SQQKRKLNRLHDILNNLRTKYSKQIKQFQEDNQSLTSDYKRLVTQFKDLQKAIRHFII
                     IDQDKFREIWLMNEAEAKELAQRAFDVDKIIHSQHLGLPWKIPNFWFLNNVGPISLQQ
                     QQKSVTQILEELLLQSEDEGTETAMSEDESYMDLPNQVSAKTTKKILVLLCDESGFLI
                     ESKLLSLLLPLEKSECYLLRLDAIFSALGIESEDDLYKMVNFFLRFKAHHLSSAQVSI
                     STHSNAERTSLVSALQHMSLMSQTDRRSSASKSDGDPTELEDQQGSDNGSLMGRELVE
                     QEDLSSPMFIHPNDVLKILDAFVTGLKKPKDARPVQRLKKDTRNNLKDTEYWESLAMV
                     IPFSKQNLWDALFKALEKYYLVLTQRAKLLMENDSLEQQNAEMQSLLQQYLQAKVNLE
                     LQVPPTQGFRMPSK"
     exon            201..288
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            289..401
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            402..585
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            586..723
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            724..810
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            811..933
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1073
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1208
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1444
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1557
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..1647
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            1648..1734
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..2006
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            2007..2150
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            2151..2253
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
     exon            2254..2455
                     /gene="Drc1"
                     /gene_synonym="Ccdc164"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caaccgggct gctggtccag gcggagctgc cagtgggtcg ccgccatgaa tccatcagga
       61 agcattgggg tcctagagca gaatggggaa gaacacttag ctgccccaat tctcgggccc
      121 tcggtgaatt ccgataaccc gcaggagcga atccaggccc ggcgccttcg catcgctgcc
      181 cgccaggaag ccagaaggcg ggaagctctg ggagagtatt tggatggcaa gaaggagagt
      241 gaggaggagc aaagcaagag ctacaaacag aaagaagaga gccgactgaa actgactaaa
      301 ctcctgctct gtgggactga gttggtgaca aatattcagg tggctgcaga cataagagag
      361 atccacagga gggttgagga agaggagaca aagcggcagc gactggaaaa gttggagaat
      421 gaagttaaga ccagccagga caaatttgat gaaatcacgt cgaagtggga agagggcaga
      481 cagaagcgga ttccgcagga actgtgggag atgctcaaca accagcaggt gcactgtgct
      541 gggctcgtag aagacaagaa caagctgatc agcgagctgc agcaggagtt aaaaataaag
      601 gatgaccagt atgtgaagga cttgaagaaa cagtcagaag acatcaccgt gcttctggag
      661 aggatggagg agcaagtgaa gagcgtgatg aagaacttcc gtcaagagct caattacatc
      721 gagaaggcct ttgagtcaga gcgacaagaa ctgctaacca ctaataagaa gaaatgggag
      781 cgagccctgc aggctcacaa tgccaaggag ctggagtacc tcatcaaccg catgaagagg
      841 gtggaggact acgagaaaca gctcaacagg cagcgggtct gggactgcga ggagtacaac
      901 tcgatcaaga tcaagctgga gcaggacgta cagattcttg agcagcagct gcagcagatg
      961 aaggcaactt accagctaaa ccaggagaag ctggagtaca acttccaggt cctgaagaag
     1021 agagacgaag agagcacggt gatcaagtcc cagcagaaga ggaaactcaa ccgcctgcac
     1081 gatatcctca acaacctgag aacaaaatac agcaagcaga taaagcagtt tcaggaggac
     1141 aaccagtccc tgacctcaga ctacaaacgg ctcgtgacgc agttcaagga cctacagaaa
     1201 gccataagac acttcatcat cattgaccag gataagtttc gggaaatttg gctgatgaat
     1261 gaagctgagg cgaaggaact ggcgcaaaga gccttcgatg tggacaagat cattcattcc
     1321 cagcacctgg ggttgccctg gaagattccc aacttctggt tcctgaataa tgtggggccg
     1381 atctccctgc agcagcagca gaagtcagtc acacaaatac tagaagaact gctgctgcag
     1441 tcagaagatg aggggacaga gacagccatg tccgaagacg agtcttacat ggacctgccc
     1501 aatcaagttt cagcaaaaac taccaaaaag atcttggtgc tcctgtgtga tgagtcgggt
     1561 ttcctcatag agagcaaact actgagtctg ctcctccccc tggagaagag tgagtgctat
     1621 ctgctgaggt tggatgccat cttttctgcc ctgggaatcg agagcgagga tgacttgtac
     1681 aagatggtaa acttcttcct tagattcaaa gcccaccatt tgtcctctgc ccaggtcagc
     1741 atctccactc acagcaatgc ggagcgcaca agcctggtgt cagcgctgca gcatatgagc
     1801 ttgatgtccc agacagacag gagaagttca gcatccaaat cagatggaga ccccacagag
     1861 ctagaggacc agcagggaag tgacaatgga agccttatgg gcagggagtt ggtagaacag
     1921 gaggacttgt cttcacccat gttcatccac cccaatgatg ttctcaagat tctggatgcc
     1981 tttgtcacgg ggctgaagaa gcccaaggac gctcgaccag tacagagatt gaagaaagat
     2041 actcgaaata acttgaagga cacagagtac tgggaatcgc tggctatggt tatccctttc
     2101 tccaagcaga acctctggga tgcgctgttc aaggccttgg agaaatacta ccttgtgctg
     2161 acccagaggg ccaagctgct gatggagaat gactccctgg agcagcagaa tgcagagatg
     2221 cagtccctgc tgcagcagta tctccaggcc aaggtaaatt tggaactgca ggtccctcca
     2281 actcagggct tccggatgcc ctcaaaatag agaaggctgt gcacagcctg gtgtcataga
     2341 gtctgcacct gtcgcctgag agccaggccc tccctggatt ctcctgagct gcatctagct
     2401 gccaaagcaa agcagtgctg ctccctgaag ttctaataaa gtctgtgaaa gcttaaaaaa
     2461 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
