LOCUS       XM_039079861            1841 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus dihydropyrimidinase (Dpys), transcript
            variant X2, mRNA.
ACCESSION   XM_039079861
VERSION     XM_039079861.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051342.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039079861.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1841
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..1841
                     /gene="Dpys"
                     /gene_synonym="DHP"
                     /note="dihydropyrimidinase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 7
                     ESTs, 42 Proteins, and 98% coverage of the annotated
                     genomic feature by RNAseq alignments, including 2 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:65135"
                     /db_xref="RGD:68376"
     CDS             114..1673
                     /gene="Dpys"
                     /gene_synonym="DHP"
                     /codon_start=1
                     /product="dihydropyrimidinase isoform X1"
                     /protein_id="XP_038935789.1"
                     /db_xref="GeneID:65135"
                     /db_xref="RGD:68376"
                     /translation="MAPQERLLIRGGRVVNDDFSQVADVLVEDGVVRALGRDLLPPGD
                     TSRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFHQGTKAALAGGTTMIIDFA
                     IPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLAQDKGVNSFKM
                     FMAYKDLYMVQDQQMYAAFSQCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHE
                     LCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADAKREGKVVYGEPIAAG
                     LGTDGTQYWNKEWRHAAHHVMGPPLRPDPSTPGFLMNLLANGDLTTTGSDNCTFNTCQ
                     KALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKK
                     GRIAVGSDADIVIWDPEATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEA
                     GVFDVTAGHGKFIPRQPFAEFIYKRVKQRDQTCTPIPVKRAPYKGEVITLKPRETKED
                     DTAGTRMQGHS"
ORIGIN      
        1 tccgccacca gggatctgcc ggccttcaac ccagcgggag agggagtttg gcacagtttg
       61 tggagaactc aaagaaaaac caactctgtt cgcagtcccc agctcctcca gccatggcac
      121 cacaagaacg acttctcatc cgcgggggtc gcgtggtcaa tgatgacttc tcacaggtgg
      181 ccgacgtgct agtggaggac ggcgtggtgc gggcgctggg acgggacttg ctgcctcccg
      241 gggacacatc ccgggggctg cggatcctag atgcagcggg caagctcgtc ctgccgggag
      301 gcatcgacac acacacgcac atgcagttcc cgttcatggg ctcgcagtca gtcgacgact
      361 tccaccaggg caccaaggct gctttggcag gaggcaccac catgatcatt gattttgcga
      421 ttcctcagaa aggcagctcc ctcattgaag cttttgagac ctggcgcaac tgggcagacc
      481 ccaaagtctg ctgtgactat agcctgcacg tggcagtgac atggtggagt gacaaggtaa
      541 aagaagaaat gaaaaccctt gcccaagata aaggcgttaa ctctttcaag atgtttatgg
      601 cctacaaaga cctgtacatg gtgcaagacc agcaaatgta cgctgccttt tctcagtgca
      661 aggagatagg ggccattgct caggtgcatg ccgagaatgg agatttgatt gcagaggggg
      721 ccaagaagat gctggcactg gggataacgg gccccgaggg gcacgagctg tgccgcccgg
      781 aagcagtgga ggcagaggcc accttgagag ccatcaccat tgctagcgct gtgaactgcc
      841 ctctatacat cgtgcacgtg atgagcaaat ccgcagcgaa ggtgatagct gatgcgaaga
      901 gagaaggaaa ggtggtctat ggagaaccaa ttgcagcagg tctgggcacg gatggcactc
      961 agtactggaa taaagaatgg cgccatgcag cccaccatgt catgggtccc ccactgagac
     1021 ctgatccatc aacgcctggc tttctcatga atctgttggc taatggcgat ctgaccacaa
     1081 cagggagtga caactgcact ttcaacacct gccaaaaagc tctagggaag gatgacttca
     1141 ctaagattcc caatggggtg aatggtgtcg aggacaggat gtcggtgata tgggaaaagg
     1201 gcgtgcacag tggcaaaatg gatgaaaata gatttgtggc agttaccagc acaaatgcag
     1261 ccaaaatctt taatctttat ccgaaaaaag gaagaatagc tgtaggctca gatgctgaca
     1321 ttgtgatctg ggacccagaa gccaccagga cgatctcagc caaaacacat catcaggccg
     1381 ttaacttcaa cattttcgag ggcatggttt gccatggggt gcccctggtg actatttcaa
     1441 gaggcagagt ggtgtatgaa gcaggcgttt tcgacgtcac agcaggacac gggaagttta
     1501 ttccgcgaca acctttcgct gagttcattt acaaacgagt caagcagcga gaccagacct
     1561 gcacacctat accggtgaag cgtgcgccct acaagggaga agtcatcaca ttgaaaccca
     1621 gagagacaaa agaagacgac acagctggga ccaggatgca gggccattcc tgatttggat
     1681 gctggggtta agcaagtgca aaggtcattg ttctgatttt gagattgtta cgtgagatgt
     1741 gaatgcttgg ccatcacggc gaagggcaag tgtaacttga taccattttc tcaactcttt
     1801 ataaccctgc caactttcaa aataaaaaaa tttaaaaaat g
//
