LOCUS       NM_001401366            1671 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus dermatopontin (Dpt), transcript variant 1, mRNA.
ACCESSION   NM_001401366 XM_039090498
VERSION     NM_001401366.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1671)
  AUTHORS   Barallobre-Barreiro,J., Gupta,S.K., Zoccarato,A.,
            Kitazume-Taneike,R., Fava,M., Yin,X., Werner,T., Hirt,M.N.,
            Zampetaki,A., Viviano,A., Chong,M., Bern,M., Kourliouros,A.,
            Domenech,N., Willeit,P., Shah,A.M., Jahangiri,M., Schaefer,L.,
            Fischer,J.W., Iozzo,R.V., Viner,R., Thum,T., Heineke,J.,
            Kichler,A., Otsu,K. and Mayr,M.
  TITLE     Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin
            Activity in Human Atrial Fibrillation
  JOURNAL   Circulation 134 (11), 817-832 (2016)
   PUBMED   27559042
REFERENCE   2  (bases 1 to 1671)
  AUTHORS   Barallobre-Barreiro,J., Oklu,R., Lynch,M., Fava,M., Baig,F.,
            Yin,X., Barwari,T., Potier,D.N., Albadawi,H., Jahangiri,M.,
            Porter,K.E., Watkins,M.T., Misra,S., Stoughton,J. and Mayr,M.
  TITLE     Extracellular matrix remodelling in response to venous
            hypertension: proteomics of human varicose veins
  JOURNAL   Cardiovasc Res 110 (3), 419-430 (2016)
   PUBMED   27068509
REFERENCE   3  (bases 1 to 1671)
  AUTHORS   Abonnenc,M., Nabeebaccus,A.A., Mayr,U., Barallobre-Barreiro,J.,
            Dong,X., Cuello,F., Sur,S., Drozdov,I., Langley,S.R., Lu,R.,
            Stathopoulou,K., Didangelos,A., Yin,X., Zimmermann,W.H., Shah,A.M.,
            Zampetaki,A. and Mayr,M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
REFERENCE   4  (bases 1 to 1671)
  AUTHORS   Liu,X., Meng,L., Shi,Q., Liu,S., Cui,C., Hu,S. and Wei,Y.
  TITLE     Dermatopontin promotes adhesion, spreading and migration of cardiac
            fibroblasts in vitro
  JOURNAL   Matrix Biol 32 (1), 23-31 (2013)
   PUBMED   23262218
  REMARK    GeneRIF: DPT participates in the ventricular remodeling process
            after MI and may act as a potential therapeutic target for
            ventricular remodeling.
REFERENCE   5  (bases 1 to 1671)
  AUTHORS   Didangelos,A., Yin,X., Mandal,K., Baumert,M., Jahangiri,M. and
            Mayr,M.
  TITLE     Proteomics characterization of extracellular space components in
            the human aorta
  JOURNAL   Mol Cell Proteomics 9 (9), 2048-2062 (2010)
   PUBMED   20551380
REFERENCE   6  (bases 1 to 1671)
  AUTHORS   Cooper,L.J., Bentley,A.J., Nieduszynski,I.A., Talabani,S.,
            Thomson,A., Utani,A., Shinkai,H., Fullwood,N.J. and Brown,G.M.
  TITLE     The role of dermatopontin in the stromal organization of the cornea
  JOURNAL   Invest Ophthalmol Vis Sci 47 (8), 3303-3310 (2006)
   PUBMED   16877395
REFERENCE   7  (bases 1 to 1671)
  AUTHORS   Tzen,C.Y. and Huang,Y.W.
  TITLE     Cloning of murine early quiescence-1 gene: the murine counterpart
            of dermatopontin gene can induce and be induced by cell quiescence
  JOURNAL   Exp Cell Res 294 (1), 30-38 (2004)
   PUBMED   14980498
REFERENCE   8  (bases 1 to 1671)
  AUTHORS   Takemoto,S., Murakami,T., Kusachi,S., Iwabu,A., Hirohata,S.,
            Nakamura,K., Sezaki,S., Havashi,J., Suezawa,C., Ninomiya,Y. and
            Tsuji,T.
  TITLE     Increased expression of dermatopontin mRNA in the infarct zone of
            experimentally induced myocardial infarction in rats: comparison
            with decorin and type I collagen mRNAs
  JOURNAL   Basic Res Cardiol 97 (6), 461-468 (2002)
   PUBMED   12395208
  REMARK    GeneRIF: Coexpression of dermatopontin mRNA with decorin and type I
            collagen mRNAs suggests that dermatopontin plays role in ECM
            (fibrillar collagen matrix) reformation in myocardial infarct along
            with decorin and type I collagen. (dermatopontin)
REFERENCE   9  (bases 1 to 1671)
  AUTHORS   Takeda,U., Utani,A., Wu,J., Adachi,E., Koseki,H., Taniguchi,M.,
            Matsumoto,T., Ohashi,T., Sato,M. and Shinkai,H.
  TITLE     Targeted disruption of dermatopontin causes abnormal collagen
            fibrillogenesis
  JOURNAL   J Invest Dermatol 119 (3), 678-683 (2002)
   PUBMED   12230512
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Feb 9, 2022 this sequence version replaced XM_039090498.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167054.1, SRR26643290.42693.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-338               JAXUCZ010000013.1  79656341-79656678
            339-464             JAXUCZ010000013.1  79668202-79668327
            465-572             JAXUCZ010000013.1  79680346-79680453
            573-1671            JAXUCZ010000013.1  79683661-79684759
FEATURES             Location/Qualifiers
     source          1..1671
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q23"
     gene            1..1671
                     /gene="Dpt"
                     /note="dermatopontin"
                     /db_xref="GeneID:289178"
                     /db_xref="RGD:1307176"
     exon            1..338
                     /gene="Dpt"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..639
                     /gene="Dpt"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1"
                     /codon_start=1
                     /product="dermatopontin isoform 1 precursor"
                     /protein_id="NP_001388295.1"
                     /db_xref="GeneID:289178"
                     /db_xref="RGD:1307176"
                     /translation="MDLTLLWVLLPLVSTAWGQYGDYGYHPYQQYQDYSDDGWVNLNR
                     QGFSYQCPHGQVVVAVRSIFNKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGME
                     WYQKCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPGHYGEDMDM
                     ISYDYDFYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFENV"
     exon            339..464
                     /gene="Dpt"
                     /inference="alignment:Splign:2.1.0"
     exon            465..572
                     /gene="Dpt"
                     /inference="alignment:Splign:2.1.0"
     exon            573..1671
                     /gene="Dpt"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacatttctt tagccaaaag ccggggcagt atggacctca ctcttctgtg ggtgcttctg
       61 ccactggtga gcacagcctg gggccagtat ggtgactacg ggtaccatcc ataccagcag
      121 taccaggact acagtgacga cggatgggtg aacctgaacc gtcagggctt cagctaccag
      181 tgtccccacg ggcaagtggt ggtagctgtg aggagcatct ttaacaagaa ggagggctct
      241 gacagacagt ggaactatgc ctgcatgccc actccccaaa gcctcgggga gcccactgag
      301 tgctggtggg aggagatcaa cagggctggc atggaatggt accagaagtg ctctaacaat
      361 ggattggtgg cggggttcca aagccgttac ttcgagtcag tgctggatcg agagtggcaa
      421 ttttactgct gccggtatag caagaggtgc ccatattcct gctggatgac aaccgagtac
      481 ccaggccact acggcgaaga catggacatg atttcctatg actatgattt ctatatgaga
      541 ggagcaacaa ccactttctc tgcagtggaa agggatcgcc agtggaagtt cataatgtgc
      601 cggatgactg actatgactg tgaattcgaa aacgtttaga ttcgccacgt acagaagtcc
      661 gggtgaaggg caagggtcct gagggtgtca tatcacatct gctaatatta attagaacaa
      721 ctgcactttt ttttttgctc tcttccctgg gatgggagct atagtgtcag ctgcctaggc
      781 ctttgtcacc acgatcacac gtataaataa acccacaatt aagccttgtt tctccctttc
      841 aacacattcc gaaacaagca tctccagttg ctgatgacag tttccttgca tagcacatgt
      901 acagcttaca gcctgctgcc cagagcacct gtcccagcct tgctgggctc gcactataac
      961 tcagcttcag attcagctta ataaacttgg agggggaggg ggaggcgctt gagagaggtg
     1021 gggataaagg ttctctatag ctaagcctgt ttgaatgaca acacccagag atctcacctg
     1081 gggtggtggg agcactctct gtcttgaggg aacatgtacc tactctctcc ttccacaaga
     1141 gccacataca cttagaagtt ccagtgaaga tctatgtgct tcagaagaga ggggacttgg
     1201 aggtgaaagg gggagtggga ggggggcttg aggacctagc tgaaagattt taggctgaaa
     1261 gaacttcctt gattcaaaga catatgtcag tagacccaac aatgagaatg aatatgaggg
     1321 ccaggaaaac ttgtgggaat cagtctcaag acagaaacag agaaagaaag aaaagtggat
     1381 aggactcaga ttgggaacct gggtagacag gagtggcaag ggaagaaggg atcttgggtt
     1441 atccacagtt tgagacacat ccggtgttcg gccatatccc cagaagccac agagatgttg
     1501 cttacacgtc tctagattgg tcctgaggtt cctcctccct ttcccgtgga gcatgaaagt
     1561 gcattctgca gagataacac catctttcct ccccctgtaa tatgtcccta gccatttgta
     1621 gctccttctt taaaaaaaaa ataaaggtaa caatattcac tgtgctatag a
//
