LOCUS       NM_031973               1720 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus dipeptidylpeptidase 7 (Dpp7), mRNA.
ACCESSION   NM_031973
VERSION     NM_031973.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1720)
  AUTHORS   Danyukova,T., Ariunbat,K., Thelen,M., Brocke-Ahmadinejad,N.,
            Mole,S.E. and Storch,S.
  TITLE     Loss of CLN7 results in depletion of soluble lysosomal proteins and
            impaired mTOR reactivation
  JOURNAL   Hum Mol Genet 27 (10), 1711-1722 (2018)
   PUBMED   29514215
REFERENCE   2  (bases 1 to 1720)
  AUTHORS   Araki,H., Li,Y., Yamamoto,Y., Haneda,M., Nishi,K., Kikkawa,R. and
            Ohkubo,I.
  TITLE     Purification, molecular cloning, and immunohistochemical
            localization of dipeptidyl peptidase II from the rat kidney and its
            identity with quiescent cell proline dipeptidase
  JOURNAL   J Biochem 129 (2), 279-288 (2001)
   PUBMED   11173530
REFERENCE   3  (bases 1 to 1720)
  AUTHORS   Fukasawa,K.M., Fukasawa,K., Higaki,K., Shiina,N., Ohno,M., Ito,S.,
            Otogoto,J. and Ota,N.
  TITLE     Cloning and functional expression of rat kidney dipeptidyl
            peptidase II
  JOURNAL   Biochem J 353 (Pt 2), 283-290 (2001)
   PUBMED   11139392
REFERENCE   4  (bases 1 to 1720)
  AUTHORS   Chiravuri,M., Agarraberes,F., Mathieu,S.L., Lee,H. and Huber,B.T.
  TITLE     Vesicular localization and characterization of a novel
            post-proline-cleaving aminodipeptidase, quiescent cell proline
            dipeptidase
  JOURNAL   J Immunol 165 (10), 5695-5702 (2000)
   PUBMED   11067927
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB048711.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB048711.1, AB038232.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMN16093045
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1720
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p13"
     gene            1..1720
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /note="dipeptidylpeptidase 7"
                     /db_xref="GeneID:83799"
                     /db_xref="RGD:71073"
     exon            1..129
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..1535
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /EC_number="3.4.14.2"
                     /note="dipeptidyl peptidase 2; DPP II; dipeptidyl
                     aminopeptidase II; quiescent cell proline dipeptidase;
                     dipeptidyl peptidase II"
                     /codon_start=1
                     /product="dipeptidyl peptidase 2 precursor"
                     /protein_id="NP_114179.1"
                     /db_xref="GeneID:83799"
                     /db_xref="RGD:71073"
                     /translation="MGLHPCSPVDHGVPSWVLVLLLTLGLCSLQATADSVLDPDFREN
                     YFEQYMDHFNFESFSNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSLANNSGFIV
                     ELAAQQEALLVFAEHRYYGKSLPFGVQSTQRGYTQLLTVEQALADFAVLLQALRHNLG
                     VQDAPTIAFGGSYGGMLSAYMRMKYPHLVAGALAASAPVIAVAGLGNPDQFFRDVTAD
                     FYGQSPKCAQAVRDAFQQIKDLFLQGAYDTISQNFGTCQSLSSPKDLTQLFGFARNAF
                     TVLAMMDYPYPTNFLGPLPANPVKVGCERLLSEGQRIMGLRALAGLVYNSSGMEPCFD
                     IYQMYQSCADPTGCGTGSNARAWDYQACTEINLTFDSNNVTDMFPEIPFSDELRQQYC
                     LDTWGVWPRPDWLQTSFWGGDLKAASNIIFSNGDLDPWAGGGIQRNLSTSIIAVTIQG
                     GAHHLDLRASNSEDPPSVVEVRKLEATLIREWVAAARLKQPAEAQWPGPK"
     exon            130..243
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     exon            244..383
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     exon            384..547
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     exon            548..683
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     exon            684..765
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     exon            766..932
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     exon            933..993
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1112
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1113..1269
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1334
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1405
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1705
                     /gene="Dpp7"
                     /gene_synonym="Dpp2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 catgactgcc agcggcccgc tcagaatcag gcatgggtct ccatccttgt tctcctgtgg
       61 accatggggt cccctcctgg gtcctggtct tgttgctgac actgggtctg tgcagcctgc
      121 aggctacagc cgacagcgtt ctagaccctg actttcgtga gaattacttt gagcagtaca
      181 tggaccattt caactttgag agtttcagca acaagacctt tggccagcgg ttcctggtgt
      241 cagataagtt ctggaagatg ggcgaggggc ccattttctt ctacacaggg aatgaggggg
      301 atatctggtc cctcgctaac aactctggct tcatagtgga actggcagcc cagcaggagg
      361 ccctgctggt ctttgctgag catcggtatt atgggaaatc gcttccattc ggtgtgcagt
      421 ccacacagcg gggatacaca cagctgctga ctgtggagca ggcgctggct gacttcgccg
      481 tgctgctcca ggccctgcgg cacaatcttg gggtccagga tgcccccacc atagcctttg
      541 gagggagtta tgggggaatg ctgagcgcct acatgaggat gaagtacccc cacctggtgg
      601 ctggggcact ggcggccagc gctcctgtta tagctgtcgc aggccttggc aaccccgacc
      661 aattcttccg agatgtcaca gcggacttct atggccagag tcccaagtgt gcccaggctg
      721 tgcgggatgc tttccagcaa atcaaagact tgttcctcca gggagcctat gacaccatca
      781 gccagaattt tgggacctgc caatcacttt ccagcccaaa ggacctgact cagctctttg
      841 ggtttgcccg gaatgcattt actgttctcg ccatgatgga ttacccgtac cctactaact
      901 ttctagggcc ccttcctgcc aaccctgtca aggtgggctg tgaacggttg ttgagtgagg
      961 gccagaggat catgggtcta cgggcactgg cagggctggt ctacaactcc tctggcatgg
     1021 aaccctgttt tgacatctac cagatgtacc aaagctgtgc tgaccccact ggctgtggca
     1081 ctggctccaa tgccagggcc tgggactacc aggcctgtac ggagatcaat ctgacctttg
     1141 acagcaacaa cgtgacagac atgttccctg aaatcccttt ctctgatgaa ctccgccagc
     1201 aatactgcct ggatacatgg ggcgtgtggc ctcggccaga ctggctgcag accagcttct
     1261 ggggtggcga ccttaaagca gccagcaaca tcattttctc caacggtgac ctagacccct
     1321 gggcaggggg tggaatccag cgcaacctga gtacatcaat cattgctgtc accatccaag
     1381 ggggagcaca tcacctagac ctcagagcat ctaactcaga agaccccccg tctgtcgtgg
     1441 aggtgcgtaa gctggaagct accctcattc gcgagtgggt agcagcagcc agactaaagc
     1501 aaccagcaga ggcacagtgg cctgggccta agtagcagcc ttccagccga gatgcagcaa
     1561 acccagagac cctgttctat gtgagccgct gtgtgacagc tcgccttacg tctgatacta
     1621 tccagactca tggtgctttg tctgagctgg acctcagcaa ggagctggtg ggagatggag
     1681 agacagaata aacacgtgct atgtcaaaaa aaaaaaaaaa
//
