LOCUS       NM_001106544            2297 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus dolichyl-phosphate mannosyltransferase subunit 1,
            catalytic (Dpm1), mRNA.
ACCESSION   NM_001106544 XM_001072659 XM_215949
VERSION     NM_001106544.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2297)
  AUTHORS   de Mateo S, Castillo J, Estanyol JM, Ballesca JL and Oliva R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   2  (bases 1 to 2297)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 2297)
  AUTHORS   Maeda Y, Tanaka S, Hino J, Kangawa K and Kinoshita T.
  TITLE     Human dolichol-phosphate-mannose synthase consists of three
            subunits, DPM1, DPM2 and DPM3
  JOURNAL   EMBO J 19 (11), 2475-2482 (2000)
   PUBMED   10835346
REFERENCE   4  (bases 1 to 2297)
  AUTHORS   Maeda Y, Tomita S, Watanabe R, Ohishi K and Kinoshita T.
  TITLE     DPM2 regulates biosynthesis of dolichol phosphate-mannose in
            mammalian cells: correct subcellular localization and stabilization
            of DPM1, and binding of dolichol phosphate
  JOURNAL   EMBO J 17 (17), 4920-4929 (1998)
   PUBMED   9724629
REFERENCE   5  (bases 1 to 2297)
  AUTHORS   Tomita S, Inoue N, Maeda Y, Ohishi K, Takeda J and Kinoshita T.
  TITLE     A homologue of Saccharomyces cerevisiae Dpm1p is not sufficient for
            synthesis of dolichol-phosphate-mannose in mammalian cells
  JOURNAL   J Biol Chem 273 (15), 9249-9254 (1998)
   PUBMED   9535917
REFERENCE   6  (bases 1 to 2297)
  AUTHORS   Sharma C, Radhakrishnamurthy B and Berenson GS.
  TITLE     Activation of dolichol-phosphate mannosyltransferase by dibutryl
            cyclic AMP in rat liver
  JOURNAL   Biochem Biophys Res Commun 155 (2), 615-621 (1988)
   PUBMED   2844175
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474005.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_215949.4, XM_001072659.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ214139.1, FQ216824.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2297
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..2297
                     /gene="Dpm1"
                     /note="dolichyl-phosphate mannosyltransferase subunit 1,
                     catalytic"
                     /db_xref="GeneID:296394"
                     /db_xref="RGD:1310120"
     exon            1..187
                     /gene="Dpm1"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..809
                     /gene="Dpm1"
                     /EC_number="2.4.1.83"
                     /note="dolichyl-phosphate mannosyltransferase 1;
                     dolichol-phosphate (beta-D) mannosyltransferase 1;
                     dolichyl-phosphate mannosyltransferase polypeptide 1,
                     catalytic subunit"
                     /codon_start=1
                     /product="dolichol-phosphate mannosyltransferase subunit
                     1"
                     /protein_id="NP_001100014.1"
                     /db_xref="GeneID:296394"
                     /db_xref="RGD:1310120"
                     /translation="MASTGASRSLAASQRPPQGRSSRQDKYSVLLPTYNERENLPLIV
                     WLLVKSFSESAINYEIIIIDDGSPDGTREVAEQLEKIYGPDRILLRPREKKLGLGTAY
                     IHGIKHATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLK
                     RKIISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSKGYVFQMEMIVRAR
                     QMDYTVGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLFATT"
     exon            188..287
                     /gene="Dpm1"
                     /inference="alignment:Splign:2.1.0"
     exon            288..321
                     /gene="Dpm1"
                     /inference="alignment:Splign:2.1.0"
     exon            322..398
                     /gene="Dpm1"
                     /inference="alignment:Splign:2.1.0"
     exon            399..424
                     /gene="Dpm1"
                     /inference="alignment:Splign:2.1.0"
     exon            425..520
                     /gene="Dpm1"
                     /inference="alignment:Splign:2.1.0"
     exon            521..589
                     /gene="Dpm1"
                     /inference="alignment:Splign:2.1.0"
     exon            590..704
                     /gene="Dpm1"
                     /inference="alignment:Splign:2.1.0"
     exon            705..2297
                     /gene="Dpm1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttccggcgc ctcgcgcaga ttcgtcatgg cttccacggg ggcgagtcgc agccttgctg
       61 cgtctcagcg gccgccgcag ggccgctcct cacggcagga caagtattcg gtgcttttgc
      121 ccacctacaa cgaacgggag aacctgccgc tcatcgtgtg gctgctggtg aagagcttct
      181 ccgagagtgc aatcaactat gaaattataa tcatagatga tggaagccca gatgggacaa
      241 gagaagttgc tgaacaactg gaaaagatct atgggccaga cagaattctc ctaagaccac
      301 gggagaaaaa gctgggcctt ggaactgcct atattcacgg aataaaacat gccacaggaa
      361 actatgtcat cattatggat gcagacctct cgcaccatcc caaatttatt cctgaattta
      421 tcaggaaaca aaaggagggt aattttgata tcgtctctgg aactcgctac aaggggaatg
      481 ggggtgttta tggatgggat ttgaaaagaa agataatcag ccgtggggcc aattttataa
      541 ctcagatttt gctgagaccg ggagcatcag atttaaccgg aagcttcaga ttataccgaa
      601 aagaagttct acagaaatta atagaaaagt gtgtctccaa aggctacgtc tttcagatgg
      661 aaatgattgt tcgagcaaga cagatggatt acaccgttgg tgaggttccg atttcatttg
      721 tggatcgagt gtatggtgaa tccaagttgg gaggaaatga aatagtctca ttcctgaaag
      781 ggttactgac tctctttgct actacataaa agaacttact catttatgct tcccgtgttc
      841 atttcaatta aaagtaagag aagcccgggt cactgatttt tatcaatgtt ctcttagcac
      901 atgaaccaaa ggtaagatac atttaatatg gatctttttt ctggagaaac tccattctat
      961 atttcaaatt aaaatgtaaa gttcttggtt tagtgagcaa tgtcctcaat tttcatgtac
     1021 attatactgt attattaata cctataaata aatgtatata ggttttgcat aaaatgttgc
     1081 tgctttcatt tagatcatgt gagggcagtt tcttatgaat atgggatact tcataaaact
     1141 agattgttat ttctttatat ctagatgtta gcaaggaagc ttaattatat ttatgaaata
     1201 tagttaatat atgaactaga aaagaaaatc tctgatcgta aagtccatct cagctttctg
     1261 accctcgatg aagtgacact ccctccctac atgcagactt ggcattatcc tggggaggtg
     1321 cttgtccaat taaagcagac ttgtgcagca gagtgtgcag tgggtgggga cagctcggca
     1381 gcaggacaca aagctgtact cttggtttcc tttttgagca acaacttcta ttcagaagaa
     1441 aagtgtttta tctcaaaata tttatttcta aattatttca atacatcaac aaaacttgtc
     1501 tccatgacag aaaaatatcg atactatttt tcttcatcca gaaaaataat ctactggtta
     1561 gaatgaaggc tcagttgctc cctgcagcca gaacacatac ttcatttatc aagtcagtga
     1621 gtttctatct gtaacatagc tttcagatca tgtagtatgt ttcagggtct ctgtgtagcc
     1681 ctggctgtct tggaactgac tttgtagacc aaacttgcct caaattcaga gatccatctg
     1741 cctctgtctc ccaagtcatg tttaggtttt tagtgaatac atgagatctg gttgcctgtc
     1801 ctttgcaaga aaaaagaaga gacatctgtc tctaagttac tgcataatca catttagtga
     1861 acagagtctg ggtgtcatat ggcccaagct gacttccaac ttactctgta gtcaaagcta
     1921 gtcttgaatt actggtcctg ttttgttcac ctctcaagtt ctaggactgt ggtgtgcaca
     1981 gtcacacacc caacctgtgt acttgttttc caccttactt gagctgctaa agaaactcaa
     2041 agtcttaagt gttgcttcca tccttctggc tgattgtaac aagggtggac atttgataag
     2101 taaagccttc cctgattttt gagcaagaaa gccttgccag gtagttccat agctgggccc
     2161 acagtgcatg ttccaagcag ggccactgtt cttgtgttcc ccttggccaa aatttgttga
     2221 gcactcatgg ggaagtgact tcttcatcct tagtaactag aatatttatt agtgttcaat
     2281 taaattttat tttaagc
//
