LOCUS       NM_001105809            2075 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus diphthamide biosynthesis 1 (Dph1), mRNA.
ACCESSION   NM_001105809 XM_001080453 XM_213396
VERSION     NM_001105809.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2075)
  AUTHORS   Chen CM and Behringer RR.
  TITLE     Ovca1 regulates cell proliferation, embryonic development, and
            tumorigenesis
  JOURNAL   Genes Dev 18 (3), 320-332 (2004)
   PUBMED   14744934
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166808.1.
            
            On May 11, 2008 this sequence version replaced NM_001105809.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166808.1, BC105814.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2075
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..2075
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /note="diphthamide biosynthesis 1"
                     /db_xref="GeneID:287523"
                     /db_xref="RGD:1562694"
     exon            1..69
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     CDS             9..1325
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /EC_number="2.5.1.108"
                     /note="diphthamide biosynthesis protein 1; DPH1 homolog"
                     /codon_start=1
                     /product="2-(3-amino-3-carboxypropyl)histidine synthase
                     subunit 1"
                     /protein_id="NP_001099279.1"
                     /db_xref="GeneID:287523"
                     /db_xref="RGD:1562694"
                     /translation="MAALVVPETSEPGSRVGPGRGRISRGRLANQIPPEILNSPQLQA
                     AVHALPSNYNFEIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTKAEVMVM
                     GDVTYGACCVDDFTARALGVDFLVHYGHSCLVPMDTSVQDFRVLYVFVDIRIDTAHLL
                     DSVRLTFTPGSSLALVSTIQFVSTLQAAAQELKADYHISVPQCKPLSPGEILGCTSPR
                     LPKEVEAVVYLGDGRFHLESVMIANPNIPSYRYDPYSKVLSREYYDHQRMQATRQEAI
                     AAARSAKFWGLILGTLGRQGSPKVLEHLESQLRNLGLPFLRLLLSEIFPSKLSLLPSV
                     DVWVQVACPRLSIDWGSAFPKPLLTPYEAAVALKEISWQQPYPMDFYAGSSLGPWTVN
                     HGRDRAPRGLCQPASDKVQQGSRGHSPVPACEGCSCADQKATPPAP"
     exon            70..222
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     exon            223..286
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     exon            287..408
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     exon            409..566
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     exon            567..688
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     exon            689..757
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     exon            758..914
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1015
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1094
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     exon            1095..1235
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1342
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..2051
                     /gene="Dph1"
                     /gene_synonym="RGD1562694"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttgagtgat ggcggcgctg gttgtgcccg agacttccga gccaggaagc cgagtcggcc
       61 ctggcagagg tcgcatctct cggggccgac tggccaatca gatcccccct gagatcctga
      121 acagtcccca gctacaggcc gctgtccatg ccctgccttc taactacaac tttgagatcc
      181 ccaagaccat ctggaggatc cagcaagccc aggccaagaa ggtggcctta caaatgccag
      241 aaggcctcct gctctttgcc tgcaccattg tggatatctt ggaaaggttc acaaaggctg
      301 aggtgatggt gatgggcgat gtgacctacg gagcatgctg tgtggacgac ttcactgcaa
      361 gggccttggg agttgacttc ctggtgcact atggccacag ctgcctagtc cccatggaca
      421 cctcagtcca agacttccgt gtgctgtatg tctttgtgga tatccggata gacactgccc
      481 accttctgga ctcggtccgc ctcaccttca ccccaggcag ctcgcttgct ctggtcagca
      541 ccattcagtt tgtgtcaact ttacaggcag ctgcccagga gctgaaagct gattatcaca
      601 tcagtgtccc acagtgcaag cccttgtccc ctggggagat cctaggctgc acgtcccctc
      661 gactacccaa ggaagtggaa gctgttgtgt atcttggaga tggccgcttc catctggagt
      721 ctgtcatgat cgccaaccct aatataccta gttaccggta cgacccatat agcaaagtcc
      781 tatccagaga atactatgac catcagcgca tgcaggccac tcgtcaggaa gccatcgctg
      841 ctgcacgctc agccaagttc tggggcctta ttctgggaac tttgggccgc cagggaagtc
      901 ccaaggtcct ggagcacttg gaatctcagc tcagaaactt gggacttcct ttcctgaggc
      961 tgcttctctc tgagatcttc cccagcaagc tcagtctact tccttcggtg gacgtgtggg
     1021 tgcaggtggc atgtccacgc ctctccattg actggggctc agcctttccc aagccactgc
     1081 tgacacccta cgaggcagct gtggccctga aagagatttc ttggcagcaa ccctacccta
     1141 tggacttcta cgctggcagc tccttagggc catggacagt gaaccatggt cgggaccgag
     1201 cacccagggg tctctgccag cctgcatccg acaaggtgca gcaggggtcc agaggccact
     1261 ctccagtccc ggcctgtgag ggctgcagct gcgcagacca gaaagctaca ccgccagctc
     1321 cctgagaggt ctggagcagc agggccctgt tctccagagg agcaacctcg aggctggtgg
     1381 ttttctgaag aggaagcaga cgttttctct gctctggaag agcccacagt gtgcaggggt
     1441 ctggaggcgg ccctggaaac ggtggcacag gcccttgaca agctggggcc ttttgatgga
     1501 cttcttggct tcagccaggg ggctgcatta gcagcttttg tgtgtgccct gggtcaggca
     1561 ggtgatcctc gcttcccctt gccaagattt atcatacttg tgtcggggtt ctgtccccga
     1621 ggccttgacc ataaggaacc catcctgcag agccccatat cattgccttc acttcatgtt
     1681 tttggggata ctgatcgagt catcccttct caggagagta tgcaattggc tagccgattc
     1741 cttggagccg tcactctcac ccactccggt ggtcatttca ttcctgcagc ggcatcccat
     1801 cgtcaggcct accttaagtt cttggatcag tttgcagaat gaaggattga caaatgtctc
     1861 tgcactgttc ccacttctct agcagctggt tgtctaatgc cctgctgggg cactcctcac
     1921 catggctagt taaaagacaa ctgtcagttc tcaggacaca cacaagacca cagagcctgt
     1981 gagaagacag tggtgggcaa gtaggggctg tcaccctgtg attgccaaac aataaaggtt
     2041 tagattttga aaaaaaaaaa aaaaaaaaaa aaaaa
//
