LOCUS       NP_001178747             357 aa            linear   ROD 24-OCT-2024
DEFINITION  zinc finger protein DPF3 isoform 1 [Rattus norvegicus].
ACCESSION   NP_001178747 XP_238462
VERSION     NP_001178747.1
DBSOURCE    REFSEQ: accession NM_001191818.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 357)
  AUTHORS   Cui,H., Schlesinger,J., Schoenhals,S., Tonjes,M., Dunkel,I.,
            Meierhofer,D., Cano,E., Schulz,K., Berger,M.F., Haack,T.,
            Abdelilah-Seyfried,S., Bulyk,M.L., Sauer,S. and Sperling,S.R.
  TITLE     Phosphorylation of the chromatin remodeling factor DPF3a induces
            cardiac hypertrophy through releasing HEY repressors from DNA
  JOURNAL   Nucleic Acids Res 44 (6), 2538-2553 (2016)
   PUBMED   26582913
  REMARK    GeneRIF: Activation of DPF3a upon hypertrophic stimuli in cardiac
            hypertrophy switches cardiac fetal gene expression from being
            silenced by HEY to being activated by BRG1.
REFERENCE   2  (residues 1 to 357)
  AUTHORS   Staahl,B.T., Tang,J., Wu,W., Sun,A., Gitler,A.D., Yoo,A.S. and
            Crabtree,G.R.
  TITLE     Kinetic analysis of npBAF to nBAF switching reveals exchange of
            SS18 with CREST and integration with neural developmental pathways
  JOURNAL   J Neurosci 33 (25), 10348-10361 (2013)
   PUBMED   23785148
REFERENCE   3  (residues 1 to 357)
  AUTHORS   Patel,D.J. and Wang,Z.
  TITLE     Readout of epigenetic modifications
  JOURNAL   Annu Rev Biochem 82, 81-118 (2013)
   PUBMED   23642229
  REMARK    Review article
REFERENCE   4  (residues 1 to 357)
  AUTHORS   Shain,A.H. and Pollack,J.R.
  TITLE     The spectrum of SWI/SNF mutations, ubiquitous in human cancers
  JOURNAL   PLoS One 8 (1), e55119 (2013)
   PUBMED   23355908
REFERENCE   5  (residues 1 to 357)
  AUTHORS   Hargreaves,D.C. and Crabtree,G.R.
  TITLE     ATP-dependent chromatin remodeling: genetics, genomics and
            mechanisms
  JOURNAL   Cell Res 21 (3), 396-420 (2011)
   PUBMED   21358755
  REMARK    Review article
REFERENCE   6  (residues 1 to 357)
  AUTHORS   Lessard,J., Wu,J.I., Ranish,J.A., Wan,M., Winslow,M.M.,
            Staahl,B.T., Wu,H., Aebersold,R., Graef,I.A. and Crabtree,G.R.
  TITLE     An essential switch in subunit composition of a chromatin
            remodeling complex during neural development
  JOURNAL   Neuron 55 (2), 201-215 (2007)
   PUBMED   17640523
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Jul 17, 2010 this sequence version replaced XP_238462.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.36350.1,
                                           SRR26643288.27414.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q31"
     Protein         1..357
                     /product="zinc finger protein DPF3 isoform 1"
                     /note="zinc finger protein DPF3; D4, zinc and double PHD
                     fingers, family 3; RGD1563913; zinc finger protein
                     DPF3-like"
                     /calculated_mol_wt=40169
     Region          13..79
                     /region_name="DPF1-3_N"
                     /note="DPF1-3, N-terminal; pfam14051"
                     /db_xref="CDD:464074"
     Region          <195..222
                     /region_name="SFP1"
                     /note="Putative transcriptional repressor regulating G2/M
                     transition [Transcription / Cell division and chromosome
                     partitioning]; COG5189"
                     /db_xref="CDD:227516"
     Region          261..>292
                     /region_name="PHD_SF"
                     /note="PHD finger superfamily; cl22851"
                     /db_xref="CDD:473978"
     Site            order(261,281..284,288)
                     /site_type="other"
                     /note="histone H3 binding site [polypeptide binding]"
                     /db_xref="CDD:276966"
     CDS             1..357
                     /gene="Dpf3"
                     /coded_by="NM_001191818.1:23..1096"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:299186"
                     /db_xref="RGD:1309052"
ORIGIN      
        1 matvihnplk algdqfykea iehcrsynsr lcaersvrlp fldsqtgvaq nncyiwmekr
       61 hrgpglapgq lytyparcwr kkrrlhpped pklrlleikp evelplkkdg ftsesttlea
      121 llrgegvekk vdareeesiq eiqrvlende nveegneeed leedipkrkn rtrgrargsa
      181 ggrrrhdaas qedhdkpyvc dicgkryknr pglsyhyaht hlaseegdea qdqetrsppn
      241 hrnenhrpqk gpdgtvipnn ycdfclggsn mnkksgrpee lvscadcgrs ahlggegrke
      301 keaaaaartt edlfgstses dtstfygfde ddleeprscr grrsgrgspt adkkssc
//
