LOCUS       NM_001108516            2404 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus double PHD fingers 2 (Dpf2), mRNA.
ACCESSION   NM_001108516 XM_001074896 XM_341998
VERSION     NM_001108516.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2404)
  AUTHORS   Vasileiou G, Vergarajauregui S, Endele S, Popp B, Buttner C, Ekici
            AB, Gerard M, Bramswig NC, Albrecht B, Clayton-Smith J, Morton J,
            Tomkins S, Low K, Weber A, Wenzel M, Altmuller J, Li Y, Wollnik B,
            Hoganson G, Plona MR, Cho MT, Thiel CT, Ludecke HJ, Strom TM,
            Calpena E, Wilkie AOM, Wieczorek D, Engel FB and Reis A.
  CONSRTM   Deciphering Developmental Disorders Study
  TITLE     Mutations in the BAF-Complex Subunit DPF2 Are Associated with
            Coffin-Siris Syndrome
  JOURNAL   Am J Hum Genet 102 (3), 468-479 (2018)
   PUBMED   29429572
REFERENCE   2  (bases 1 to 2404)
  AUTHORS   Huber FM, Greenblatt SM, Davenport AM, Martinez C, Xu Y, Vu LP,
            Nimer SD and Hoelz A.
  TITLE     Histone-binding of DPF2 mediates its repressive role in myeloid
            differentiation
  JOURNAL   Proc Natl Acad Sci U S A 114 (23), 6016-6021 (2017)
   PUBMED   28533407
REFERENCE   3  (bases 1 to 2404)
  AUTHORS   Singh AP and Archer TK.
  TITLE     Analysis of the SWI/SNF chromatin-remodeling complex during early
            heart development and BAF250a repression cardiac gene transcription
            during P19 cell differentiation
  JOURNAL   Nucleic Acids Res 42 (5), 2958-2975 (2014)
   PUBMED   24335282
REFERENCE   4  (bases 1 to 2404)
  AUTHORS   Shain AH and Pollack JR.
  TITLE     The spectrum of SWI/SNF mutations, ubiquitous in human cancers
  JOURNAL   PLoS One 8 (1), e55119 (2013)
   PUBMED   23355908
REFERENCE   5  (bases 1 to 2404)
  AUTHORS   Hargreaves DC and Crabtree GR.
  TITLE     ATP-dependent chromatin remodeling: genetics, genomics and
            mechanisms
  JOURNAL   Cell Res 21 (3), 396-420 (2011)
   PUBMED   21358755
  REMARK    Review article
REFERENCE   6  (bases 1 to 2404)
  AUTHORS   Mahajan MC, Narlikar GJ, Boyapaty G, Kingston RE and Weissman SM.
  TITLE     Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF
            form a chromatin remodeling complex at the beta-globin locus
            control region
  JOURNAL   Proc Natl Acad Sci U S A 102 (42), 15012-15017 (2005)
   PUBMED   16217013
REFERENCE   7  (bases 1 to 2404)
  AUTHORS   Gabig TG, Crean CD, Klenk A, Long H, Copeland NG, Gilbert DJ,
            Jenkins NA, Quincey D, Parente F, Lespinasse F, Carle GF, Gaudray
            P, Zhang CX, Calender A, Hoeppener J, Kas K, Thakker RV, Farnebo F,
            Teh BT, Larsson C, Piehl F, Lagercrantz J, Khodaei S, Carson E and
            Weber G.
  TITLE     Expression and chromosomal localization of the Requiem gene
  JOURNAL   Mamm Genome 9 (8), 660-665 (1998)
   PUBMED   9680388
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_341998.3, XM_001074896.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166788.1, SRR8487230.69156.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2404
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..2404
                     /gene="Dpf2"
                     /note="double PHD fingers 2"
                     /db_xref="GeneID:361711"
                     /db_xref="RGD:1311699"
     exon            1..83
                     /gene="Dpf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1227
                     /gene="Dpf2"
                     /note="D4, zinc and double PHD fingers family 2"
                     /codon_start=1
                     /product="zinc finger protein ubi-d4"
                     /protein_id="NP_001101986.1"
                     /db_xref="GeneID:361711"
                     /db_xref="RGD:1311699"
                     /translation="MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDS
                     QTGVAQSNCYIWMEKRHRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDT
                     DQTLKKEGLISQDGSSLEALLRTDPLEKRGAPDPRVDDDSLGEFPVTNSRARKRILEP
                     DDFLDDLDDEDYEEDTPKRRGKGKSKSKGVSSARKKLDASILEDRDKPYACDICGKRY
                     KNRPGLSYHYAHSHLAEEEGEDKEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFC
                     LGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNLCG
                     TSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCLDLLKEKASIYQNQNSS"
     exon            84..244
                     /gene="Dpf2"
                     /inference="alignment:Splign:2.1.0"
     exon            245..352
                     /gene="Dpf2"
                     /inference="alignment:Splign:2.1.0"
     exon            353..516
                     /gene="Dpf2"
                     /inference="alignment:Splign:2.1.0"
     exon            517..609
                     /gene="Dpf2"
                     /inference="alignment:Splign:2.1.0"
     exon            610..688
                     /gene="Dpf2"
                     /inference="alignment:Splign:2.1.0"
     exon            689..826
                     /gene="Dpf2"
                     /inference="alignment:Splign:2.1.0"
     exon            827..955
                     /gene="Dpf2"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1068
                     /gene="Dpf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1150
                     /gene="Dpf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..2404
                     /gene="Dpf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcgttgcg ggcttcgggg cctcccggcc tgagggagag gaactgggaa gatggcggct
       61 gtggtggaga atgtagtgaa gctccttggg gagcagtact acaaagatgc catggaacag
      121 tgccacaatt ataatgcccg cctgtgtgcc gagcgtagcg tgcgtctgcc tttcttggac
      181 tctcagactg gagtagccca gagcaattgt tacatctgga tggaaaagcg gcaccggggc
      241 ccaggattgg cctctggaca gttgtactcc taccctgccc gacgctggcg aaaaaagcgt
      301 cgagcccacc cacctgagga tcccaggctt tctttcccgt ctattaagcc agacacggac
      361 cagactctga agaaagaggg ccttatctcc caggatggca gcagtttaga ggctctgctg
      421 cgtactgatc ccctggagaa acggggtgcc ccagatcccc gagttgatga tgacagcctg
      481 ggcgagtttc ctgttaccaa cagtcgagca cggaagcgga tccttgaacc cgatgacttc
      541 ctagacgacc ttgatgacga ggactatgaa gaagatactc caaagcgtcg gggaaagggg
      601 aaatccaaga gtaagggtgt gagcagtgcc cggaagaagc tggacgcttc catcctggag
      661 gaccgggata agccctatgc ctgtgacatt tgtggaaaac gttacaagaa ccgacctggc
      721 ctcagttacc actatgccca ttcccacctg gctgaagagg aaggagagga caaagaagac
      781 tcccaaccac ccactcctgt gtcccagagg tctgaggagc agaaatccaa gaaaggacct
      841 gatgggttgg ccctgcctaa caactactgt gacttctgcc tgggagactc aaaaatcaac
      901 aagaagacag ggcagcctga ggagctggtg tcctgttctg actgtggccg ctcagggcat
      961 ccgtcctgcc tgcagttcac ccctgtgatg atggcagccg tgaagaccta ccgctggcag
     1021 tgcatcgagt gcaagtgctg caacctctgc ggcacttcag agaacgacga ccagctgctt
     1081 ttctgtgatg actgtgaccg tggctaccac atgtactgtc tcaccccttc catgtctgag
     1141 cctcctgaag gaagttggag ttgccacctg tgtttggatc tgctgaagga gaaagcgtcc
     1201 atctaccaga accagaactc ctcctgatgt gccacccagc tcccctgcat cgaaggccgt
     1261 tgctctctct ttaccttggt tttcattccc cctctctcct ctttcaccct gtagtcctac
     1321 caacctgcct ttggcaacag cacagggagg tggcagcttt gactgcctct ggccccaagc
     1381 cctcagggag taaggagcag catgctgccc caggactgac ctgtgggccc aacttctctc
     1441 tgttctccaa gaagtgcatt cactctgctt gccttgggcc caagaccctg gtgattacag
     1501 ggctcaaata gggtcctctg agaaggaata tgagagcagc tcactgtctc aagccttgcc
     1561 tagcctcacc cccaaccccc tttggtttcc tgggttttgt cccagagatg agccaggctg
     1621 ggccttttct gaagcagctg gagtgagctg gctgaagtgg cacttgccag gaccttttca
     1681 tatcctagtc tgcttccctt tgcctcctgc caaagcagtc ccctgtcctc tgccatgcta
     1741 catgaggctc tgtgcttgag ctagagtgct ctcaacacct cctggctctc cctgtcccac
     1801 aaagggacaa gcagcttaaa cctgtccttc ctgtgcttgg ctggcttgct cacaggtgct
     1861 ctctggctac ccaaacattt cccatcctca gaacctactg tcttctgcct ccttccttgt
     1921 tccctttggt tttgtaggga gagggatagt gtcaagggct gtgccagcag cttggggccg
     1981 cagggagagg ttggataatg tgcctgtttt ttaactcgat aaaaaagcct acctccaaaa
     2041 tccccttttc gttcttcctg gacctgggca ttcagcctcc tgcccttaac tgaatcagga
     2101 gcctctgcct cctgcctgtg catcctggct cccaggtcac aggttggtcc cctttccttg
     2161 cacgctagct agtagctggt aaggtcttca caccctgatt tttctgtttc ctgcttagtg
     2221 gcactgacat taagtaggag gggacagtcc atgccaagat actctggagt gggcttcccc
     2281 cttggctgtg ggcaggcagg ccctaactgt tgttttctgc aaagttgagg ccccctcttc
     2341 acatatttag ttcctgtatt caaaacatta gtaaaaataa acatttttac agagccctct
     2401 gctg
//
