LOCUS       NP_001008384             488 aa            linear   ROD 27-APR-2025
DEFINITION  dipeptidase 3 precursor [Rattus norvegicus].
ACCESSION   NP_001008384 XP_344762
VERSION     NP_001008384.1
DBSOURCE    REFSEQ: accession NM_001008383.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 488)
  AUTHORS   Yoshitake,H., Yanagida,M., Maruyama,M., Takamori,K., Hasegawa,A.
            and Araki,Y.
  TITLE     Molecular characterization and expression of dipeptidase 3, a
            testis-specific membrane-bound dipeptidase: complex formation with
            TEX101, a germ-cell-specific antigen in the mouse testis
  JOURNAL   J Reprod Immunol 90 (2), 202-213 (2011)
   PUBMED   21724266
REFERENCE   2  (residues 1 to 488)
  AUTHORS   Kogo,H., Kowa-Sugiyama,H., Yamada,K., Bolor,H., Tsutsumi,M.,
            Ohye,T., Inagaki,H., Taniguchi,M., Toda,T. and Kurahashi,H.
  TITLE     Screening of genes involved in chromosome segregation during
            meiosis I: toward the identification of genes responsible for
            infertility in humans
  JOURNAL   J Hum Genet 55 (5), 293-299 (2010)
   PUBMED   20339383
REFERENCE   3  (residues 1 to 488)
  AUTHORS   Habib,G.M., Shi,Z.Z., Cuevas,A.A. and Lieberman,M.W.
  TITLE     Identification of two additional members of the membrane-bound
            dipeptidase family
  JOURNAL   FASEB J 17 (10), 1313-1315 (2003)
   PUBMED   12738806
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085826.1.
            
            On Dec 16, 2004 this sequence version replaced XP_344762.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085826.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     Protein         1..488
                     /product="dipeptidase 3 precursor"
                     /EC_number="3.4.13.19"
                     /note="putative membrane-bound dipeptidase 3"
                     /calculated_mol_wt=49600
     sig_peptide     1..35
                     /note="/evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5U2X4.1)"
                     /calculated_mol_wt=3789
     mat_peptide     36..459
                     /product="Dipeptidase 3. /id=PRO_0000231615"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U2X4.1)"
                     /calculated_mol_wt=46608
     Region          41..74
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U2X4.1)"
     Region          84..404
                     /region_name="Peptidase_M19"
                     /note="Membrane dipeptidase (Peptidase family M19);
                     pfam01244"
                     /db_xref="CDD:395996"
     Site            order(94,96,140,193,266,287,298,356,359)
                     /site_type="active"
                     /db_xref="CDD:238626"
     Site            order(142,151..153,155..156,159,163,203..204,206..207,
                     210..211)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238626"
     Site            331
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5U2X4.1)"
     CDS             1..488
                     /gene="Dpep3"
                     /coded_by="NM_001008383.1:116..1582"
                     /db_xref="GeneID:364994"
                     /db_xref="RGD:1305484"
ORIGIN      
        1 mqptgpegpr alslrplghr lsllgvllii pslwvtcnqt tpslssapts pgassamttp
       61 gipndtttsg vtsdprlreq alalmrdfpl vdghndlpll lrelfqnklq dvnlhnftrg
      121 qtsldrlrdg lvgaqfwsay ipcqtqdrda vrvaleqidl irrmcsaype lelvtsadgl
      181 nstqklacli glegghsldt slavlrsfye lgvryltltf tcstpwaesa tkfrhhfytn
      241 isgltsfgek vveemnrigm midlshasdt lvkqtleasr apvifshsaa rsvcdnllnv
      301 pddilqllkk nggivmvtls mgvlqcslla nvstvadhfd hirtvigsef igiggsydgs
      361 grfpqgledv stypvlleel lrrgwgeqel qgvlrgnllr vfrqveqvre kslgqspvev
      421 vfperqqsst chshllpqsq dahlkvtklp ssqvlqrask appcpllglv aavtspaftl
      481 wlccsghr
//
