LOCUS       NM_001107826            2039 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus dolichol kinase (Dolk), mRNA.
ACCESSION   NM_001107826 XM_001079536 XM_231121
VERSION     NM_001107826.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2039)
  AUTHORS   Shridas P and Waechter CJ.
  TITLE     Human dolichol kinase, a polytopic endoplasmic reticulum membrane
            protein with a cytoplasmically oriented CTP-binding site
  JOURNAL   J Biol Chem 281 (42), 31696-31704 (2006)
   PUBMED   16923818
REFERENCE   2  (bases 1 to 2039)
  AUTHORS   Fernandez F, Shridas P, Jiang S, Aebi M and Waechter CJ.
  TITLE     Expression and characterization of a human cDNA that complements
            the temperature-sensitive defect in dolichol kinase activity in the
            yeast sec59-1 mutant: the enzymatic phosphorylation of dolichol and
            diacylglycerol are catalyzed by separate CTP-mediated kinase
            activities in Saccharomyces cerevisiae
  JOURNAL   Glycobiology 12 (9), 555-562 (2002)
   PUBMED   12213788
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474001.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_231121.2, XM_001079536.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2039
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..2039
                     /gene="Dolk"
                     /gene_synonym="Tmem15"
                     /note="dolichol kinase"
                     /db_xref="GeneID:311847"
                     /db_xref="RGD:1310821"
     exon            1..2039
                     /gene="Dolk"
                     /gene_synonym="Tmem15"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..1871
                     /gene="Dolk"
                     /gene_synonym="Tmem15"
                     /EC_number="2.7.1.108"
                     /note="transmembrane protein 15"
                     /codon_start=1
                     /product="dolichol kinase"
                     /protein_id="NP_001101296.1"
                     /db_xref="GeneID:311847"
                     /db_xref="RGD:1310821"
                     /translation="MTRQCPPQAPESGFALSGSVLAEAAVVFAVVLSIHAAVWDRYSW
                     CAVALAVQAFYVQYKWDRLLQQGNAVFQFRMSANSGLLPASMVMPLLGLVMKERCLTA
                     GNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCAISGLAGGIIIYIMKHSLS
                     VGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTESQG
                     DPVDFFLLVVVVGMVLMGVFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHWL
                     IRRNPLLWLLQFLFYTETRIYLLAYWSLLATMACLVVLYQNAKRSSSESKKHKAPTIT
                     RKYFHFIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSL
                     FLDERDSGPLILTHIYLLLGMSLPIWLIPRPCAQKGSLGGARALVPYAGVLAVGVGDT
                     VASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSI
                     STVSLLEAYTTQIDNLLLPLYLLILLMA"
ORIGIN      
        1 tccgcggcgg tggcagtgga gcctgtaaga ggtgaagagt gcaaacatct gctacaccgt
       61 aggttgaaag cggtggaggg tgactgggcg ccggctccca ggcctcagag tggcccgcgg
      121 tgaagcactc ttttggaaac tggagaaggt cgctgcctgg gtgaaattgc tgcccctcag
      181 cttggcgggt tgagggctcc agaagccaag gcgtccctag tcaccaagct tcttctccca
      241 agatacccag gcctagagac atgacccgac agtgccctcc ccaagccccg gagtctgggt
      301 ttgcgctgag cgggtcagtg ctggcggagg ctgcagtggt gttcgcagtg gtgctgagca
      361 tccacgctgc agtgtgggac cgatactcct ggtgcgccgt ggccttagca gtgcaggcct
      421 tctacgtcca gtacaagtgg gaccggctgc tccagcaggg gaatgctgtt ttccagttcc
      481 gaatgtccgc gaacagtggc ttactaccgg cctccatggt catgcctttg cttgggctgg
      541 tcatgaagga gcgctgcctg actgcaggga acccatactt cgagcgcttc ggcattgtgg
      601 ttgcagccac tggcatggca gtggccctct tctcctcggt gttggcactg ggcattactc
      661 gcccggtgcc caccaatact tgtgccatct cgggtttggc cggaggtatt atcatttata
      721 ttatgaagca ctcgctcagt gtgggcgagg tgatcgaggt cctggaagtc ctgctaatat
      781 tcgtttatct caacatgatc ctgctgtacc tgctgccccg ctgcttcact cctggggagg
      841 cactgctggt attgggtggc attagcttcg tcctcaacca gctcatcaag cgctctctga
      901 ctgaaagcca gggggaccca gtggacttct tcctgttggt ggtggtggtg gggatggtgc
      961 tcatgggtgt ctttttcagc accctctttg tcttcatgga ttcgggcacc tgggcctctt
     1021 ctatcttctt ccacctcatg acctgtgtgc tgggccttgg tgtggttctg ccctggctgc
     1081 actggctcat tcgtaggaac cccctgctct ggcttcttca gttcctcttc tacacagaaa
     1141 ctcgcatcta cctcctagcc tattggtcct tgctggccac catggcctgc ctggtggtgc
     1201 tgtaccagaa tgccaagcgg tcatcttctg agtccaagaa gcacaaggct cctaccatta
     1261 ccagaaagta tttccacttc attgtggtgg ccacttacat ccccggtatc atctttgacc
     1321 ggccactgct gtatgtggcc gccaccgtgt gtctggccgt cttcatcttc ctggagtatg
     1381 tgcgctattt cagaatcaag cccctgggtc acactctgcg cagccttctg tccctcttcc
     1441 tggatgaacg ggacagcggg cccctcatcc tgacgcacat ctacctgctt ctgggcatgt
     1501 ctcttcccat ttggctgatc cccagaccct gtgcacagaa gggcagcctc ggaggagcaa
     1561 gagccctggt cccctatgct ggggtcctgg ctgtgggtgt gggcgatact gtggcctcca
     1621 tatttggcag caccatgggg gagatccgct ggcctggaac taagaaaaca ttcgagggaa
     1681 ctatgacatc tatatttgca caaatcatct ctgtggctct gatcctaatc tttgacagtg
     1741 gagtagacct gaactacagc tatgcttgga ttttggggtc catcagcact gtgtcgcttc
     1801 tggaagcata cacaactcag atagacaatc tcctgttgcc cctctaccta ctgattttgc
     1861 tgatggccta gtaccgaata gcagctgtaa tgggggaacg gaaattggga gaatgaatgg
     1921 tcctcacagc agctagccgc ttggacacca agaactaagg gatgaaaggc agatttagct
     1981 tcctcccaga agatgaagcc agaaagttga ttcagactta aaataaagaa gcaaagctt
//
