LOCUS       NM_001108438            1554 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus docking protein 4 (Dok4), mRNA.
ACCESSION   NM_001108438 XM_001058478 XM_341642
VERSION     NM_001108438.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1554)
  AUTHORS   Blugeon C, Le Crom S, Richard L, Vallat JM, Charnay P and Decker L.
  TITLE     Dok4 is involved in Schwann cell myelination and axonal interaction
            in vitro
  JOURNAL   Glia 59 (3), 351-362 (2011)
   PUBMED   21264944
  REMARK    GeneRIF: Dok4 is a novel player in Schwann cell-axon interaction
            and is required at early stages of myelination; it also aids
            Schwann cell migration and proliferation.
REFERENCE   2  (bases 1 to 1554)
  AUTHORS   Grimm J, Sachs M, Britsch S, Di Cesare S, Schwarz-Romond T, Alitalo
            K and Birchmeier W.
  TITLE     Novel p62dok family members, dok-4 and dok-5, are substrates of the
            c-Ret receptor tyrosine kinase and mediate neuronal differentiation
  JOURNAL   J Cell Biol 154 (2), 345-354 (2001)
   PUBMED   11470823
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158749.1.
            
            On Jan 27, 2008 this sequence version replaced NM_001108438.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158749.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132263, SAMD00132271
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1554
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p13"
     gene            1..1554
                     /gene="Dok4"
                     /note="docking protein 4"
                     /db_xref="GeneID:361364"
                     /db_xref="RGD:1310084"
     exon            1..147
                     /gene="Dok4"
                     /inference="alignment:Splign:2.1.0"
     exon            148..359
                     /gene="Dok4"
                     /inference="alignment:Splign:2.1.0"
     CDS             294..1271
                     /gene="Dok4"
                     /codon_start=1
                     /product="docking protein 4"
                     /protein_id="NP_001101908.1"
                     /db_xref="GeneID:361364"
                     /db_xref="RGD:1310084"
                     /translation="MATNFNDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEK
                     YPDEKSVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEE
                     WYKTLSVECLGSRLNDISLGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQIT
                     HENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQ
                     IYQRVHSATLAIAEQHKRVLLEMEKNVRLLNKGTEHYSYPCTPTAMLPRSAYWHHITG
                     SQNIAEASSYGEGYGAAQASSETDLLNRFILLKPKPRQEDSSETKTPPQ"
     exon            360..467
                     /gene="Dok4"
                     /inference="alignment:Splign:2.1.0"
     exon            468..582
                     /gene="Dok4"
                     /inference="alignment:Splign:2.1.0"
     exon            583..702
                     /gene="Dok4"
                     /inference="alignment:Splign:2.1.0"
     exon            703..892
                     /gene="Dok4"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1031
                     /gene="Dok4"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1152
                     /gene="Dok4"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1523
                     /gene="Dok4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgctggatc cggagctggc ggctgcgctt cgctccagtc tacaaccgga gcggcgcgct
       61 gccaccccac cttcccagcc gcgccgggtc gagacccggg catgagctcg ccccgcgtcc
      121 cgcggagcca gcgcctccgg cgcctagcag gagctgggcg aaggagccgc tagaacaatg
      181 ctgaggtggg ggaggtgagg agtgtcttaa acaggtgatc aggggagacc aagccacctg
      241 ggcaccctcc ccggactcag cccagccggc accccaaaga cagtggggca accatggcga
      301 ccaatttcaa cgacatcgtc aagcaaggct atgtgaagat gaagagcagg aagcttggga
      361 tttaccggag gtgctggctg gtgttccgaa aatcttccag taaggggccc cagcggctgg
      421 agaagtatcc tgatgagaag tcagtgtgcc tccgaggctg ccccaaggtg actgagatca
      481 gcaacgtcaa gtgtgtcacg aggctcccca aggagaccaa gagacaggcg gtggccatca
      541 tattcacgga tgactctgct cgcaccttca cttgtgactc agagctggag gcagaggagt
      601 ggtacaagac actgtcagta gagtgtctgg gatcacggct caatgacatc agtctgggag
      661 agccagacct cctggcccca ggagtacagt gtgagcagac agatcgcttc aatgtcttcc
      721 tgttaccctg ccctaacctg gacgtgtatg gcgagtgcaa actgcagatc actcacgaga
      781 acatctacct ctgggacata cacaaccccc gcgtgaagct cgtctcgtgg cccctctgct
      841 ctttgcgccg ttatggccga gatgccacac gatttacctt tgaggcgggc aggatgtgtg
      901 acgctgggga aggactctat acctttcaga cacaggaggg ggagcagatt taccagcggg
      961 ttcacagtgc caccctggcc atcgctgagc agcacaagcg ggtcctgctg gaaatggaga
     1021 agaatgtgag gctgctgaac aagggcaccg agcactactc ctatccctgt acacccacgg
     1081 ccatgctgcc ccgcagtgcg tactggcacc atatcacggg ttctcagaac atcgctgaag
     1141 cctccagcta tggtgaagga tatggggcag cccaggccag ctcagaaaca gacctcctga
     1201 acagattcat cctgcttaag ccaaagccta ggcaggagga cagcagtgag accaagaccc
     1261 ctccccagtg acagctgcta ggctgcaaga actcacgact gctgggccac ttgctggagg
     1321 acagctcact gcagcagtcc atggacagcc tcaaggagct ggtggccaag agccagagag
     1381 caagctgtcc ctcttgccct caagggtgag gctggacctc agtacatggc tggccacacc
     1441 acctgagcat gaggggctag agccaccgtg gaactataca ctgttaatgg ttttaatata
     1501 tatggcttat aacatattct gtaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
