LOCUS       NM_001107336            1527 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus docking protein 3 (Dok3), mRNA.
ACCESSION   NM_001107336 XM_001069255 XM_225170
VERSION     NM_001107336.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1527)
  AUTHORS   Kang,B.W., Jeon,H.S., Chae,Y.S., Lee,S.J., Park,J.S., Choi,G.S. and
            Kim,J.G.
  TITLE     Impact of Genetic Variation in MicroRNA-binding Site on
            Susceptibility to Colorectal Cancer
  JOURNAL   Anticancer Res 36 (7), 3353-3361 (2016)
   PUBMED   27354594
REFERENCE   2  (bases 1 to 1527)
  AUTHORS   Berger,A.H., Niki,M., Morotti,A., Taylor,B.S., Socci,N.D.,
            Viale,A., Brennan,C., Szoke,J., Motoi,N., Rothman,P.B.,
            Teruya-Feldstein,J., Gerald,W.L., Ladanyi,M. and Pandolfi,P.P.
  TITLE     Identification of DOK genes as lung tumor suppressors
  JOURNAL   Nat Genet 42 (3), 216-223 (2010)
   PUBMED   20139980
REFERENCE   3  (bases 1 to 1527)
  AUTHORS   Cong,F., Yuan,B. and Goff,S.P.
  TITLE     Characterization of a novel member of the DOK family that binds and
            modulates Abl signaling
  JOURNAL   Mol Cell Biol 19 (12), 8314-8325 (1999)
   PUBMED   10567556
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474032.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_225170.3, XM_001069255.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166772.1, FQ235097.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132301, SAMD00132307
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1527
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1527
                     /gene="Dok3"
                     /note="docking protein 3"
                     /db_xref="GeneID:306760"
                     /db_xref="RGD:1311840"
     exon            1..90
                     /gene="Dok3"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..1359
                     /gene="Dok3"
                     /note="downstream of tyrosine kinase 3"
                     /codon_start=1
                     /product="docking protein 3"
                     /protein_id="NP_001100806.1"
                     /db_xref="GeneID:306760"
                     /db_xref="RGD:1311840"
                     /translation="MESVETPVKDGLLYQQHMKFGKKCWRKVWALLYAGGPSGVARLE
                     SWDVRDGGLGPGGDRPAGPGRRGERRIIRLADCVSVLPADGESCPRDTGAFLITTTER
                     SHLLAAQHRQSWMDPICQLAFPSTGECSSGSGQAESPKRGFVPMEENSIYSSWQEVAE
                     FPVVVQRTEATTRCQLKGPYLLVLGQDDIQLRETSKPQACYSWPYRFLRKFGSDKGVF
                     SFEAGRRCDSGEGLFAFSSPRAPDICGAVAAAIARQRERLPELAMSPPCPLPRALSLP
                     SLEPPGELREVAPEYELAPSRKLPLTDPGPQSLPLLLSPTQDGTASSLYASVCKQTSK
                     HKATVEHLYENVFMLEASPGLSNGGPEAQEGPPGGRSPLGSPIYHNSEELSWPGSAHD
                     SNLEAQYRRLLELELDDAGGAGRPGAQTGIKAKLVTLLTRERKKGPAPCDRP"
     exon            91..396
                     /gene="Dok3"
                     /inference="alignment:Splign:2.1.0"
     exon            397..496
                     /gene="Dok3"
                     /inference="alignment:Splign:2.1.0"
     exon            497..669
                     /gene="Dok3"
                     /inference="alignment:Splign:2.1.0"
     exon            670..1527
                     /gene="Dok3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgggacttca gaactgttgt ggccatggaa tctgtggaga cacctgtcaa ggacggcctc
       61 ctctaccagc agcacatgaa gtttggcaag aaatgctggc gcaaagtgtg ggctctgctg
      121 tatgcaggag gcccgtcggg agtagctcgg ctagaaagct gggacgttcg tgatggtggc
      181 ctggggccag gaggtgacag gcccgcaggg cctggccgta gaggggaacg ccggatcata
      241 cgcttggctg actgtgtatc tgttctgccg gcggatggtg agagttgccc cagggacact
      301 ggggccttcc tgatcaccac cactgagcga agccacctgc tggctgcaca gcaccgccag
      361 tcatggatgg accccatctg ccagctggcc ttcccgagta ccggagaatg ttcctcagga
      421 tcaggacagg ctgagagtcc aaaaaggggc tttgtcccca tggaggaaaa ctccatctac
      481 tcctcctggc aggaagttgc tgagtttccg gtggtggtgc agaggacaga ggccaccacc
      541 cgctgccagc tgaagggacc ctacctcctg gtgctgggcc aagatgacat tcagctgcgg
      601 gagacttcca agccccaggc ctgctatagc tggccctacc gattcctgcg caagtttggc
      661 tctgacaagg gtgtgttctc ttttgaggct ggccgccgct gcgactcagg agagggcctt
      721 tttgccttca gtagtccgcg tgcaccagac atatgtggag ctgtggccgc agccattgcc
      781 cgtcagcggg agcgtcttcc agagttggcc atgtccccac cctgccccct ccctcgggcc
      841 ctctccctgc cttccctaga gccccctgga gagcttcggg aggtggcccc agaatatgag
      901 ctggcccctt ccagaaagct gcctctaact gatcctggac ctcaaagcct acccctgctg
      961 ctcagcccca cacaagacgg gacagcctcc agtctctatg cgtctgtgtg caagcagacc
     1021 agcaagcaca aagccaccgt ggagcatctc tacgagaacg tgttcatgct ggaggccagc
     1081 cctgggctgt ccaacggggg tcctgaggcc caagagggcc ctcctggtgg ccgcagcccc
     1141 ctgggcagcc ccatctacca taacagcgag gagctgagtt ggcctggctc ggcccacgac
     1201 agcaatctgg aagcccagta ccggaggctg ctggagctgg agctcgatga tgctggaggc
     1261 gccgggcgtc ctggagcaca gacaggcatc aaggccaagc tggtaaccct gctgactcgt
     1321 gaacggaaga agggccccgc cccctgcgac cggccctgaa ggcccgtttg gcctcagcag
     1381 ggcagaggtg atgtcctaaa aaaacatgaa caacttttga cctgcaggga caagccagga
     1441 ggcttagtga ggagccacac tctgcctacc tccttccctc agactgtgta cagattgacc
     1501 agtaataaag cttgcctatc aacttcc
//
