LOCUS       NM_001394344            6575 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus dedicator of cytokinesis 6 (Dock6), transcript
            variant 1, mRNA.
ACCESSION   NM_001394344 XM_006242657
VERSION     NM_001394344.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6575)
  AUTHORS   Zhang,Z.Y., Sun,Y.Y., Wang,H.C., Fu,W.N. and Sun,C.F.
  TITLE     Overexpression of DOCK6 in oral squamous cell cancer promotes
            cellular migration and invasion and is associated with poor
            prognosis
  JOURNAL   Arch Oral Biol 133, 105297 (2022)
   PUBMED   34742001
REFERENCE   2  (bases 1 to 6575)
  AUTHORS   Chi,H.C., Tsai,C.Y., Wang,C.S., Yang,H.Y., Lo,C.H., Wang,W.J.,
            Lee,K.F., Lai,L.Y., Hong,J.H., Chang,Y.F., Tsai,M.M., Yeh,C.T.,
            Wu,C.H., Hsieh,C.C., Wang,L.H., Chen,W.J. and Lin,K.H.
  TITLE     DOCK6 promotes chemo- and radioresistance of gastric cancer by
            modulating WNT/beta-catenin signaling and cancer stem cell traits
  JOURNAL   Oncogene 39 (37), 5933-5949 (2020)
   PUBMED   32753649
REFERENCE   3  (bases 1 to 6575)
  AUTHORS   Li,X., Jiang,M., Chen,D., Xu,B., Wang,R., Chu,Y., Wang,W., Zhou,L.,
            Lei,Z., Nie,Y., Fan,D., Shang,Y., Wu,K. and Liang,J.
  TITLE     miR-148b-3p inhibits gastric cancer metastasis by inhibiting the
            Dock6/Rac1/Cdc42 axis
  JOURNAL   J Exp Clin Cancer Res 37 (1), 71 (2018)
   PUBMED   29587866
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6575)
  AUTHORS   Sukalo,M., Tilsen,F., Kayserili,H., Muller,D., Tuysuz,B.,
            Ruddy,D.M., Wakeling,E., Orstavik,K.H., Snape,K.M., Trembath,R., De
            Smedt,M., van der Aa,N., Skalej,M., Mundlos,S., Wuyts,W.,
            Southgate,L. and Zenker,M.
  TITLE     DOCK6 mutations are responsible for a distinct autosomal-recessive
            variant of Adams-Oliver syndrome associated with brain and eye
            anomalies
  JOURNAL   Hum Mutat 36 (6), 593-598 (2015)
   PUBMED   25824905
  REMARK    Erratum:[Hum Mutat. 2015 Nov;36(11):1112. PMID: 26457590]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Apr 15, 2021 this sequence version replaced XM_006242657.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-78                JAXUCZ010000008.1  28670571-28670648   c
            79-166              JAXUCZ010000008.1  28665008-28665095   c
            167-342             JAXUCZ010000008.1  28664345-28664520   c
            343-411             JAXUCZ010000008.1  28663219-28663287   c
            412-541             JAXUCZ010000008.1  28662874-28663003   c
            542-754             JAXUCZ010000008.1  28661701-28661913   c
            755-840             JAXUCZ010000008.1  28660486-28660571   c
            841-907             JAXUCZ010000008.1  28659223-28659289   c
            908-1057            JAXUCZ010000008.1  28658833-28658982   c
            1058-1138           JAXUCZ010000008.1  28656847-28656927   c
            1139-1292           JAXUCZ010000008.1  28656595-28656748   c
            1293-1420           JAXUCZ010000008.1  28656349-28656476   c
            1421-1514           JAXUCZ010000008.1  28656150-28656243   c
            1515-1677           JAXUCZ010000008.1  28655767-28655929   c
            1678-1795           JAXUCZ010000008.1  28650375-28650492   c
            1796-1866           JAXUCZ010000008.1  28650218-28650288   c
            1867-2005           JAXUCZ010000008.1  28649874-28650012   c
            2006-2107           JAXUCZ010000008.1  28649664-28649765   c
            2108-2194           JAXUCZ010000008.1  28648665-28648751   c
            2195-2426           JAXUCZ010000008.1  28648216-28648447   c
            2427-2588           JAXUCZ010000008.1  28647840-28648001   c
            2589-2752           JAXUCZ010000008.1  28647099-28647262   c
            2753-2857           JAXUCZ010000008.1  28646353-28646457   c
            2858-2950           JAXUCZ010000008.1  28642819-28642911   c
            2951-3046           JAXUCZ010000008.1  28642477-28642572   c
            3047-3187           JAXUCZ010000008.1  28641998-28642138   c
            3188-3301           JAXUCZ010000008.1  28639868-28639981   c
            3302-3472           JAXUCZ010000008.1  28639587-28639757   c
            3473-3612           JAXUCZ010000008.1  28638512-28638651   c
            3613-3782           JAXUCZ010000008.1  28638254-28638423   c
            3783-3943           JAXUCZ010000008.1  28635789-28635949   c
            3944-4126           JAXUCZ010000008.1  28635263-28635445   c
            4127-4253           JAXUCZ010000008.1  28634426-28634552   c
            4254-4338           JAXUCZ010000008.1  28634011-28634095   c
            4339-4435           JAXUCZ010000008.1  28633147-28633243   c
            4436-4570           JAXUCZ010000008.1  28632872-28633006   c
            4571-4723           JAXUCZ010000008.1  28631776-28631928   c
            4724-4882           JAXUCZ010000008.1  28631359-28631517   c
            4883-4983           JAXUCZ010000008.1  28630187-28630287   c
            4984-5176           JAXUCZ010000008.1  28628778-28628970   c
            5177-5320           JAXUCZ010000008.1  28628551-28628694   c
            5321-5452           JAXUCZ010000008.1  28623124-28623255   c
            5453-5467           JAXUCZ010000008.1  28623020-28623034   c
            5468-5593           JAXUCZ010000008.1  28621315-28621440   c
            5594-5683           JAXUCZ010000008.1  28621137-28621226   c
            5684-5920           JAXUCZ010000008.1  28620704-28620940   c
            5921-6064           JAXUCZ010000008.1  28620053-28620196   c
            6065-6171           JAXUCZ010000008.1  28619855-28619961   c
            6172-6333           JAXUCZ010000008.1  28619492-28619653   c
            6334-6575           JAXUCZ010000008.1  28618523-28618764   c
FEATURES             Location/Qualifiers
     source          1..6575
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..6575
                     /gene="Dock6"
                     /note="dedicator of cytokinesis 6"
                     /db_xref="GeneID:367039"
                     /db_xref="RGD:1306517"
     exon            1..78
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..6376
                     /gene="Dock6"
                     /note="isoform 1 is encoded by transcript variant 1;
                     dedicator of cytokinesis protein 6"
                     /codon_start=1
                     /product="dedicator of cytokinesis protein 6 isoform 1"
                     /protein_id="NP_001381273.1"
                     /db_xref="GeneID:367039"
                     /db_xref="RGD:1306517"
                     /translation="MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRSSSSLG
                     VPLTEVIEPLDFEDVLLSRPPEVEPGPLRDMIEFPADDLELLKQPRECRTTESGVPED
                     GKLDAQVRAAVEMYSEDWVIVRRRYQHLSTAYSPITTETQRERQKGLTCQVFEQDTPG
                     DERTGPEDVDDSQHCSGSPEDTPRSSGASGVFSLRNLAADSLLPTLLERAAPEDVDRR
                     NEALRRQHRAPALLTLYPAPDEDEAVERCSHPEPPREHFGQRILVKCLSLKFEIEIEP
                     IFGTLALYDVREKKKISENFYFDLNSDSVKGLLRAHGTHPAISTLARSAIFSVTYPSP
                     DIFLVVKLEKVLQQGDISECCEPYMVMKEADTVKNKEKLEKLRLAAEQFCTRLGRYRM
                     PFAWTAVHLANIVSSVGPQDRDSDSEGERRPTWAERRRRGPQDRSYSGDDACSFSSFR
                     PATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKIDISPAPENLH
                     FCLSPELLHVKPYPDPRGRPTKEILEFPAREVYAPHTCYRNLLFVYPHSLNFSSRQGS
                     VRNLAVRIQYMAGEDQSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLRLP
                     ACVTENHHLFFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPP
                     PSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQDPHLDKFFTLVHVLEEGIFP
                     FRLKETVLSEGTMEQELRASLAALRLASPEPLVAFSHHVLDKLVRLVVRPPVICGQMV
                     NLGRGAFEAMAHVASLVHRNLEAVQDSRGHCPLLAAYVHYAFRLPGGDLGLPGEVPPA
                     TVQAATLARGSGRPASLYLARSKSISSSNPDLAVVPGSVDDEVSRILASKGVDRSHSW
                     VNSAYAPGGSKAVLRRVPPYCGADPRQAIDRNSSRASSYLEASSSALPAPQLRHTVQK
                     LLHEELALQWVVSGSAVRELVLQHAWFFFQLMVKSMELHLLLGQRLDTPRKLRFPGRF
                     LDDIAALVASVGLEVITRVHKDMELAERLNASLAFFLSDLLSIADRGYIFSLVRAHYK
                     QVATRLQSAPNPAALLTLRMDFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQ
                     SSTFSSQAPDPKVISMFELSGPFRQQHFLSGLLLTELALALDPEAEGASLLHKKAITA
                     VHNLLCSHDVDSRYTDATVKAKVAELYLPLLSLARDTLPRLHGFAEGSGQRSRLASML
                     DSDTEGEGDIGGTINPSVAMAIAGGPLAPGSRTSISQGPSTAARSGCPLSAESSRTLL
                     VCVLWVLKNAEPALLQRWAADLALPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFK
                     KSLDMKARLEEAILGTIGARQEMVRRSRERSPFGNQENVRWRKSVTHWRQTSDRVDKT
                     KDEVEHEALVDGNLATEASLVVLDMLEIIVQTVMLSEARESILGAVLKVVLYSLGSAQ
                     SALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLY
                     LLMRQNFEIGHNFARVKMLVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDLGLRD
                     STFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLMDLMYRIARGYQGSPDLRLTWLQN
                     MASKHAELGNHAEAAQCMVHAAALVAEYLALLEDSRHLPVGCVSFQNVSSNVLEESAI
                     SDDILSPDEEGFCSGKNFTDLGLVGLLEQAAAYFTMGGLYEAVNEVYKNLIPILEAHR
                     DYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYGARFGDLDEQEFVYKEPSI
                     TKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKLKLDPQKAYIQITYVEPHFDTYEL
                     KDRVTYFDRNYGLRAFLFCTPFTPDGRAHGELAEQHKRKTLLSTEHAFPYIKTRIRVC
                     HREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVA
                     QVFLSEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERHYS
                     RLREALQPLLTQRLPQLLAPSSTSLRNSINRSSFRKTDL"
     exon            79..166
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            167..342
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            343..411
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            412..541
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            542..754
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            755..840
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            841..907
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1057
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1138
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1292
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1420
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1514
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            1515..1677
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..1795
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            1796..1866
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            1867..2005
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            2006..2107
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            2108..2194
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            2195..2426
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            2427..2588
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            2589..2752
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            2753..2857
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            2858..2950
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            2951..3046
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            3047..3187
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            3188..3301
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            3302..3472
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            3473..3612
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            3613..3782
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            3783..3943
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            3944..4126
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            4127..4253
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            4254..4338
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            4339..4435
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            4436..4570
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            4571..4723
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            4724..4882
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            4883..4983
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            4984..5176
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            5177..5320
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            5321..5452
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            5453..5467
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            5468..5593
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            5594..5683
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            5684..5920
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            5921..6064
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            6065..6171
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            6172..6333
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
     exon            6334..6575
                     /gene="Dock6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agactccgga ggctgcggcg ggacgcgggg cgtcatggcg gcctcggagc gccgcgcctt
       61 cgctcacaag atcaacagga ctgtggctgc tgaggtccgg aagcaggtgt cccgggaacg
      121 cagcggctcg ccccactcca gccgacgctc cagtagttct ctgggggtcc ctctgacgga
      181 ggtcattgaa cccctggact ttgaggatgt gcttctgagc cggccacctg aagtagagcc
      241 cggtcccctc agggacatga tagagtttcc agctgatgac ctagaactac tgaagcaacc
      301 ccgagaatgc cggaccacag aatctggggt gccagaggat ggaaagttgg acgcccaggt
      361 gagggctgcg gtggagatgt actcagagga ctgggtcatt gtacgcagaa ggtaccagca
      421 cctgagtaca gcatacagtc ccatcactac agagacacag cgagagcggc agaaaggcct
      481 cacctgccag gtcttcgagc aggatacccc tggggatgag aggacaggtc ccgaggatgt
      541 ggatgactcc cagcactgtt ctggctcccc agaggacacc cctcgaagca gtggagcctc
      601 aggcgtcttc agcctgagga acctggctgc agactcccta ctgcccacac tgcttgagcg
      661 ggcagcccct gaggacgtgg accggcgcaa tgaagccctc aggaggcagc accgggcccc
      721 cgccctgctc accttgtacc cggcacctga tgaggatgaa gctgtagaac gctgcagcca
      781 cccggagcca ccccgagagc acttcgggca gaggatcctg gtgaaatgtc tgtcactcaa
      841 gtttgagatt gaaatcgagc ccatctttgg caccttggcc ctatatgatg tgcgggagaa
      901 gaaaaagatt tcagaaaact tctactttga cctaaactcg gactccgtta aggggctgct
      961 ccgggcccat ggcacccacc cggccatctc caccttggcg cgctctgcca tcttctccgt
     1021 gacctacccc tctcctgaca tcttcctggt tgtcaagctg gaaaaagtgc tgcagcaggg
     1081 ggacatcagc gagtgctgcg aaccctacat ggtgatgaag gaggcggaca cggtgaagaa
     1141 caaagagaag ctggagaagc tgcgcctggc cgcggagcag ttctgcacca ggctgggccg
     1201 ctaccgcatg cccttcgcct ggacagcggt gcacctggct aacatcgtga gcagcgtcgg
     1261 gccacaggac cgggattccg actccgaggg cgaacgcaga cccacttggg ccgaacgccg
     1321 ccgtcggggg ccccaggatc gaagctatag tggggatgat gcctgcagct tctccagctt
     1381 ccgcccagcc acgttaactg tcaccaactt ttttaaacag gaggcagaac ggctcagtga
     1441 tgaagacctt ttcaagtttt tggcggacat gcggcgacca tcttccctgc tgaggcgatt
     1501 acgacctgtg actgctcagc tcaagattga catctcccct gcacccgaga acctacactt
     1561 ctgcctgtcc cctgagttac ttcatgtcaa gccctaccct gaccccaggg gacggcccac
     1621 caaggagatc ctggagttcc ctgcccgtga ggtctacgcc ccccatacct gttacaggaa
     1681 cctgctcttc gtgtacccac acagtctcaa tttcagcagt cgccagggct ctgtgcgtaa
     1741 cctggccgtg cgcatccagt acatggcagg ggaagaccag agccaggcct tgccggtcat
     1801 ctttgggaaa tctagctgca gcgagttcac ccgagaggcc ttcacaccag tggtctatca
     1861 taacaagtct cctgaattct acgaggagtt caagctacga cttcctgcct gcgtgaccga
     1921 gaaccatcac ctctttttta ccttctacca tgttagctgc cagccccggc caggaacagc
     1981 cctggagaca cctgtgggct tcacttggat tcctctgtta caacatggcc gcctgaggac
     2041 tggccccttc tgcctgcccg tgtccgtgga ccagcctccc cccagctatt cagtcctgac
     2101 cccagatgta gcactgccgg gcatgcgctg ggtggacggt cacaagggcg tgttcagtgt
     2161 ggagctcaca gctgtgtcgt ctgttcaccc ccaggacccc cacttggaca agttcttcac
     2221 cctggtgcat gttctagagg aagggatctt tccattccgg ctcaaggaga cggtgctgag
     2281 cgagggcacc atggagcagg agctgcgggc cagcctggca gccctgcgcc ttgccagccc
     2341 ggagcccctt gtggcctttt cccaccacgt cctagacaag cttgtccgct tggttgtgcg
     2401 gccaccggtc atttgtggcc agatggtgaa cctaggtcgt ggggcctttg aagctatggc
     2461 tcatgtcgcc agccttgtgc accggaacct ggaggccgtc caagattccc gtggtcactg
     2521 cccactgctg gctgcctatg tccactatgc ctttcgcctt cctggcggtg acctcggcct
     2581 gccgggggag gtccctccag caactgtaca ggctgccaca ctggcccgag gctctggccg
     2641 ccccgccagc ctctacctgg cacggtctaa gagcattagc agcagcaacc ctgacctggc
     2701 tgtggtcccc ggctctgtag acgatgaggt gtcccgcatc ctagccagca agggcgtcga
     2761 tcgctcacac tcctgggtga attctgctta tgctccggga ggcagcaagg ctgtgctgcg
     2821 gagggtgccc ccatactgtg gggctgaccc cagacaggcc atcgaccgca actctagccg
     2881 ggcctcctct taccttgagg cctcttcctc ggccctgcca gcccctcagc tgagacacac
     2941 tgtgcagaag ctgctgcacg aggagctggc tctgcagtgg gtggtgagtg gcagcgcggt
     3001 tcgcgagctg gtcctgcagc acgcctggtt cttcttccag ctcatggtaa aaagtatgga
     3061 gctacacttg ctcctgggcc agcgcctgga cactccccgg aagctgcgct tccctgggcg
     3121 cttcctggat gacatcgcgg ccctggtggc ttctgtgggc ctggaagtca tcacccgagt
     3181 ccataaggac atggagctag ctgaacgcct caacgctagc ttggccttct tcctcagtga
     3241 tctcctgtcc atagcggacc gaggctacat cttcagcctg gtacgcgctc actacaagca
     3301 ggtggccact cggctgcagt ctgcccccaa cccagctgca ctgctcacac tacgaatgga
     3361 cttcacccgc atcctgtgta gccacgagca ctacgtgacc cttaacctcc cctgttgccc
     3421 cctgtcacct ccagcctccc cctccccctc ggtgtcctcc actacctccc agagctctac
     3481 cttctccagc caggcccctg acccgaaggt gatcagcatg ttcgagctga gtgggccgtt
     3541 caggcagcag catttcctgt ccggactcct gctgacagag ctggccctgg ccctggatcc
     3601 agaagctgag ggggcatccc ttctgcacaa gaaggccatt actgctgtgc acaacctgct
     3661 gtgcagccat gatgttgact cccgctacac agatgctacg gtgaaggcca aggtggccga
     3721 gctgtacctg cctctgctct ccctcgcaag ggataccctg ccacgactgc acggctttgc
     3781 cgagggctcg gggcagcggt caagactggc ttccatgctg gactcagaca cagaaggtga
     3841 aggggacatt ggaggcacca tcaacccatc tgtggccatg gccatcgctg ggggacctct
     3901 ggctcctggc tcgcggacca gcatttccca gggaccttca acagcagctc gttcaggctg
     3961 tcccctctct gctgagtcca gccggacctt actggtgtgt gtgctgtggg tcttgaaaaa
     4021 tgcagagcct gcactcctgc agcgctgggc tgccgacctg gccctgcccc agctgggacg
     4081 cctcctcgac ttactctacc tctgtctggc tgccttcgag tacaagggga aaaaagcctt
     4141 cgagcggatc aacagcctca cgttcaagaa gtccctggac atgaaagccc ggctggagga
     4201 ggccatccta ggcaccatcg gggctcggca ggagatggtg cggcggagcc gggagagaag
     4261 tccatttgga aaccaagaga atgttcgctg gcgtaagagc gtcacacact ggagacagac
     4321 ctcagaccgc gtggacaaga ccaaggatga agtggaacat gaagctctgg tggatggaaa
     4381 cctggcaaca gaggccagcc tggtggttct ggacatgttg gagatcatcg tgcagacagt
     4441 gatgctgtca gaggcccgtg agagcatcct gggtgccgtg ctgaaagttg tcctctacag
     4501 tcttgggagc gcccagagtg ccctcttcct acagcacggc ctggccaccc agcgggcact
     4561 ggtctccaag tttccagagc tgcttttcga ggaagacacg gagctttgtg ccgacctctg
     4621 cctgaggctt ctgcgacact gtggcagccg catcagcacc atccgcacgc acgccagcgc
     4681 ctcgctctac ctgcttatgc gccagaactt cgaaattggc cataactttg cccgtgtgaa
     4741 gatgctggtg accatgtccc tgtcatctct tgtggggaca actcagaact ttagcgaaga
     4801 gcatttgaga agatccctca aaaccatcct gacctacgca gaggaggacc tagggctgag
     4861 ggacagcacc ttcgctgagc aggttcagga cctcatgttc aacctgcaca tgatcctgac
     4921 agacactgtg aagatgaagg agcaccagga ggaccccgag atgctcatgg acctcatgta
     4981 cagaattgcc cggggctacc aaggctctcc agacctgcgg ttgacatggc tgcagaacat
     5041 ggccagcaaa catgcggagc tgggcaatca tgcagaggct gcccaatgca tggtccatgc
     5101 cgctgccctg gtggccgaat acctggccct cctcgaggac agtcgccacc tgcctgtggg
     5161 ctgtgtgtcc ttccagaatg tctcgtccaa cgtgctggag gaatctgcca tctctgatga
     5221 catcctgtcg cctgacgagg agggcttctg ctctgggaag aacttcacgg acctgggtct
     5281 ggtggggctg ctggagcagg cagccgccta cttcaccatg gggggtctgt atgaagcagt
     5341 gaacgaggtc tacaaaaacc tcatccccat ccttgaagcc caccgagact acaagaagct
     5401 ggccgcagtg catgggaagc tacaggaggc cttcaccaaa atcatgcacc agagctctgg
     5461 ctgggagcgt gtgtttggga cgtacttccg agtgggcttc tatggtgcac gatttggtga
     5521 cctggatgaa caagagtttg tgtacaagga accgtcgatc acaaagctgg cagagatctc
     5581 acaccggcta gaggagttct atacggagcg gttcggggat gatgtggtgg agatcatcaa
     5641 agattccaac ccggtagata agctcaagct ggacccacag aaggcctaca tccagataac
     5701 atacgtggag ccgcactttg acacttatga gctcaaggac cgggtgacct actttgaccg
     5761 aaactatggg cttcgggcct tcctcttctg cacacccttc acgccggatg ggcgtgcgca
     5821 cggagagttg gcagagcagc acaaacgcaa gacgctgctg agcacagagc atgcctttcc
     5881 ctacatcaag acacgcatcc gagtgtgcca ccgtgaggag acagtgctga caccagtgga
     5941 ggtggccatt gaagacatgc agaagaagac acgggagctg gcctttgcca ccgagcagga
     6001 tcctccagat gccaagatgc tgcagatggt tctgcagggc tccgtgggac ccactgtaaa
     6061 ccagggtccc ttggaagtag cccaggtatt tttgtcagag atcccagaag atcccaagct
     6121 cttccgacat cacaacaaac tacggctctg cttcaaggat ttctgcaaaa agtgtgagga
     6181 tgcactaaga aagaacaagg ccctgattgg accagaccag aaggagtacc accgggaact
     6241 ggaacgccac tacagccgcc tccgggaggc actgcagcct ctgctcacgc agcgtctgcc
     6301 ccagctgttg gcaccaagtt ccaccagcct caggaactcc atcaacagat caagtttccg
     6361 gaagactgat ctctgatgaa acagctaaaa gccacaccca gaagaccagc acctacacct
     6421 cagctgcctg tgcctttctg gagtcaaacc tactccctca tccatggggt gaccacaaag
     6481 tccttggagc tgggctctgt ctgtctgcac tgatggattt ctaagctttg tttttatttg
     6541 tttgtttttt aatttaaagt gagttttata tacaa
//
