LOCUS       XM_039078124            8495 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus dedicator of cytokinesis 4 (Dock4),
            transcript variant X1, mRNA.
ACCESSION   XM_039078124
VERSION     XM_039078124.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051341.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 9, 2024 this sequence was replaced by
            NM_001427091.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8495
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..8495
                     /gene="Dock4"
                     /note="dedicator of cytokinesis 4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 43 ESTs, 8 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     95 samples with support for all annotated introns"
                     /db_xref="GeneID:366608"
                     /db_xref="RGD:1561724"
     CDS             320..6256
                     /gene="Dock4"
                     /codon_start=1
                     /product="dedicator of cytokinesis protein 4 isoform X1"
                     /protein_id="XP_038934052.1"
                     /db_xref="GeneID:366608"
                     /db_xref="RGD:1561724"
                     /translation="MWIPTEHEKYGVVIASFRGTVPYGLSLEIGDTVQILEKCDGWYR
                     GFALKNPNIKGIFPSSYVHLKNACVKNKGQFEMVIPTEDSVITEMTSTLRDWGSMWKQ
                     LYVRNEGDLFHRLWHIMNEILDLRRQVLVGHLTHDRMKDVKRHITARLDWGNEQLGLD
                     LVPRKEYAMVDPEDISITELYRLMEHRHRKKDTPVQASSHHLFVQMKSLMCSNLGEEL
                     EVIFSLFDSKENRPISERFFLRLNRNGLPKAPDKPERHCSLFVDLGSSELRKDIYITV
                     HIIRIGRMGAGEKKNACSVQYRRPFGCAVLSIADLLTGETKDDLVLKVYMCNTESEWY
                     QIHENIIKKLNARYNLTGSNAGLAVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFS
                     DIIMPGEMRNDLYITVERGEFEKGGKSVARNVEVTMFIVDSNGQPLKDFISFGSGEPL
                     ASEYHSFVLYHNNSPRWSELLKLPIPVDKFRGSHIRFEFRHCSTKEKGEKKLFGFSFV
                     PLMQEDGRTLPDGTHELIVHKCEENTNLQDTTRYLKFPFSKVIFLGNNNQTMKATKES
                     FWITSFLCSTKLTQNGDMLDLLKWRTHPDKITGCLSKLKEIDGSEIVKFLQDTLDTLF
                     GILDENSQKYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVL
                     KWYVDRITEAERQEHIQEVLKAQEYIFKYIVQSRRLFSLATGGQNEEEFRCCIQELLM
                     SVRFFLSQESKGTGALSQSQAVFLSSFPAVYSELLKLFDVREVANLVQDTLGSLPTIM
                     HVDDSLQAIKLQCIGKTVESQLYTNPDSRYILLPVVLHHLHIHLQEQKDLIMCARILS
                     NVFCLIKKNSSEKSVLEEIDVIVASLLDILLRTILEITSRPQASSSAMRLQFQDVTGE
                     FVACLLSLLRQMTDRHYQQLLNSFNTKEELRDFLLQIFTVFRILIRPEMFPKDWTVMR
                     LVANNVIITTVLYLSDALRKNFLNENFDYKIWDSYFYLAVIFINQLCLQLEMFTPSKK
                     KKVLEKYGDMRVTMGCEIFSMWQNLGEHKLHFIPALIGPFLEVTLIPQPDLRNVMIPI
                     FHDMMDWEQRRSGNFKQVEAKLIDKLDSLMSEGKGDETYRELFNSIIPLFGPYPSLLK
                     KIERETWRESGVSLIATVTRLMERLLDYRDCMKIGEVDGKKIGCTVSLLNFYKTELNK
                     EEMYIRYIHKLYDLHLKAQNFTEAAYTLLLYDELLEWSDRPLREFLTYPMQTEWQRKE
                     HLHLTIIQNFDRGKCWENGIILCRKIAEQYESYYDYRNLSKMRMMEASLYDKIMDQQR
                     LEPEFFRVGFYGKKFPFFLRNKEFVCRGHDYERLEAFQQRMLNEFPHAIAMQHANQPD
                     ETIFQAEAQYLQIYAVTPIPESQEVLQREGVPDNIKSFYKVNHIWKFRYDRPFHKGTK
                     DKENEFKSLWVERTSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKT
                     LISQCQSRQMQNINPLTMCLNGVIDAAVNGGVSRYQEAFFVKDYILSHPEDGEKIARL
                     RELMLEQAQILEFGLAVHEKFVPQDMRPLHKKLVDQFFVMKSSFGIQEFPACIQASPV
                     HFPNGSPRVCRNSAPASMSPDGTRVIPRRSPLSYPAVNRYSSSSLSSQASAEVSNITG
                     QSESSDEVFNMQPSPSTSSLSSTHSASPNVTSSAPSSARASPLLSDKHKHSRENSCLS
                     PRDRPCSAIYPTPVEPSQRMLFNHIGDGALPRSDPNLSAPEKAVNPTPSSWSLDSGKE
                     AKNMSDSGKLISPPVPPRPTQTASPARHTTSVSPSPAGRSPLKSSVQSFTPSPVEYNS
                     PGLSSNSPVLSGSYSSGISSLSRCSTSETSGFENQANEQSVPVPVPVPVPMPVPSFSG
                     SEEPVRKESKTPPPYSVYERTLRRPVPLPHSLSIPVTSEPPALPPKPLAARSSHLENG
                     TRRTEPGPRPRPLPRKVSQL"
ORIGIN      
        1 gggggtgcgc ccgcgagtgc cccggcgtgt tcgcttagtt cagtgaatca gaacaatgac
       61 tgcgccgccg ggtccccgag agcgcgtcgc agggctgtga gcagccgcgg ccggcagagc
      121 agcgggcggc tccgtctcgt ccgtgtagtg tcagtgtccg ctcgggagcc ccgggagaag
      181 cccctgccca gcgccgcagc ccgcgcgatc tgctgtgctc cagcgccgca gctgctcttc
      241 gggagccgtg cattgttgtg agccactgga ggggcgcggg gattgcatag cccggagccc
      301 ctcagcgccc tttatagcca tgtggatacc tacggagcac gagaaatacg gcgtggttat
      361 tgccagtttt cgaggcaccg tcccatatgg cctgtcattg gaaattggag atactgttca
      421 gatcctggag aagtgcgatg gctggtacag aggatttgcc ttaaaaaacc ccaatatcaa
      481 gggtatattt ccttccagct atgttcactt gaaaaatgcc tgtgtaaaga acaaaggaca
      541 atttgagatg gttattccca ctgaagattc tgttatcaca gagatgacat caacattaag
      601 agactgggga agcatgtgga aacaactcta tgtcagaaat gaaggggatc tcttccaccg
      661 cctgtggcac atcatgaatg aaatcctcga tctgcggcgg caggtgctag tcggccacct
      721 cacccacgac aggatgaagg atgtgaagcg tcatattact gcgcggctgg attggggaaa
      781 tgaacaactg ggactcgacc tggtgcctag gaaggagtac gcaatggtag acccagagga
      841 catcagcatc actgagctgt accgactgat ggaacatcga catcggaaga aggacactcc
      901 tgtgcaggcc agcagtcacc atctctttgt ccagatgaag agcctcatgt gttccaacct
      961 gggagaggag ctggaggtca tcttctcgct cttcgacagt aaagagaatc gcccaatcag
     1021 tgagagattt ttcttgagac tgaataggaa tgggcttccc aaagccccgg ataagcccga
     1081 aagacactgt tctctctttg tggacttggg cagcagtgaa ctcaggaagg acatctatat
     1141 taccgtgcac attatccgaa ttggacgaat gggagcagga gaaaaaaaga acgcctgcag
     1201 tgttcaatat cggcgaccgt ttggctgtgc ggttcttagc attgcagacc ttctcacagg
     1261 agagacgaag gatgaccttg tcctgaaagt gtacatgtgt aatacagaga gtgagtggta
     1321 ccagatccac gagaacatca tcaaaaagct gaatgcacgc tacaatttga ctggctccaa
     1381 tgcaggatta gcagtttccc tccagctgtt acacggagac attgaacaga tcagaagaga
     1441 atactcctcg gtgttctctc acggagtatc cataactcgg aagctgggtt tttctgacat
     1501 tataatgcct ggtgaaatga ggaatgattt atatatcacc gtagaaaggg gagagtttga
     1561 gaaaggcggc aagagtgtgg ccagaaatgt ggaagtcaca atgttcatag tagacagtaa
     1621 tggtcagccc ttaaaggatt ttatctcctt tggttctgga gagccactgg ctagtgagta
     1681 ccactccttt gtgctttatc acaacaacag tcccaggtgg tcggagctgc tgaaacttcc
     1741 cattcctgtg gataaattca ggggctccca catccgcttt gagttccggc attgttccac
     1801 aaaggagaaa ggagagaaga agttgttcgg tttctctttc gtacccttga tgcaagagga
     1861 tggaaggact ctcccagatg gcacacacga gctcatcgtg cataagtgtg aagaaaacac
     1921 aaaccttcag gatactaccc gctacctcaa gtttccattt tccaaggtca tcttccttgg
     1981 gaacaataat caaaccatga aggccacaaa ggaatccttt tggataacat catttctgtg
     2041 ttccacaaaa ctcactcaga atggtgatat gcttgatctt ttgaaatgga gaacccaccc
     2101 agacaagatc acaggctgtc tctctaagtt aaaagaaatc gatggctcag agatagtaaa
     2161 gtttctccaa gacacactgg ataccttgtt tggaatatta gatgaaaatt cccaaaaata
     2221 tgggtctaaa gtatttgatt ctttggtcca cataataaat ttgctacaag atagcaagtt
     2281 ccatcatttt aagcctgtca tggacactta cattgagagt cactttgctg gggcacttgc
     2341 atacagagat ctcatcaaag tgctcaagtg gtacgtggac aggataacgg aagcagagcg
     2401 ccaggagcat atccaggaag tgttgaaggc acaagaatac atttttaagt atatagttca
     2461 atcccgaagg ctgttttccc tggccactgg agggcagaat gaagaggaat tccgctgctg
     2521 catccaggag ctcctcatgt ctgtccgctt cttcctctca caagagagca aagggactgg
     2581 agcgttatct cagtcacagg ctgtgttcct gagctccttc ccagctgtgt attcagaact
     2641 gttgaagctc tttgatgtcc gggaagtggc caacttggta caggacaccc tgggcagcct
     2701 gccgaccatc atgcatgtgg acgattccct gcaggcgatc aagcttcagt gcattggcaa
     2761 aactgtagag agccagctct acaccaaccc agactcaagg tacattctcc tgcctgtcgt
     2821 actgcatcac ctccacattc acttgcaaga acagaaggac ttgatcatgt gtgcacgtat
     2881 ccttagcaac gtattctgtc tcatcaagaa aaatagctca gaaaagtctg tactggagga
     2941 aatagacgtg atcgtggcca gcttgctgga tatcctgctc aggaccatac tggagatcac
     3001 cagtcggcct caagcatcca gctccgccat gaggctgcag ttccaggatg tcactgggga
     3061 atttgttgcc tgtctccttt ccctattacg acaaatgaca gatagacatt atcagcaact
     3121 tctgaatagt ttcaatacta aagaggagct gagggatttc ttgctgcaga tttttaccgt
     3181 gttccgaata ttgatacgcc cagagatgtt tcccaaggac tggactgtca tgcgcctggt
     3241 tgctaacaat gttatcatta caaccgttct gtacctctcc gatgctctcc gtaagaactt
     3301 cttaaatgaa aactttgatt ataagatctg ggattcctac ttttacctcg ctgtcatttt
     3361 tataaaccag ttgtgtctgc agctggagat gttcacacct tccaaaaaga aaaaggtgct
     3421 agaaaagtat ggtgatatgc gggtcaccat gggttgtgaa attttcagca tgtggcaaaa
     3481 cctaggagaa cacaaacttc atttcatccc ggccctgatt gggccctttc tggaagtgac
     3541 cttgataccc cagccagatc tccggaacgt catgattcct atttttcacg atatgatgga
     3601 ttgggagcaa aggagaagtg gcaactttaa gcaggtggaa gccaagctaa ttgacaaatt
     3661 ggatagcctg atgtcagagg gcaaaggtga tgaaacatac cgtgagctct tcaacagtat
     3721 aattccacta tttggtccct accctagtct actaaagaaa attgagcggg aaacatggag
     3781 ggaaagtggc gtttcattaa ttgccactgt cactcggctg atggagaggt tgttagacta
     3841 cagggactgc atgaaaatag gagaagtgga tggcaagaag attggctgca cagtgagcct
     3901 gctgaacttc tataagacgg agctgaacaa ggaggagatg tacatccgct acatccacaa
     3961 actctatgat ctgcatctca aggcgcagaa cttcacagag gctgcctaca ccctcctgct
     4021 gtatgacgag ctgctggagt ggtctgatcg gcccctcagg gagttcctga cctaccccat
     4081 gcagactgag tggcagcgca aggagcacct gcacctcacc atcatccaga actttgatcg
     4141 aggcaaatgt tgggagaatg gcattatcct gtgccggaag attgcagagc aatatgagag
     4201 ttactatgac tacaggaacc tgagcaagat gaggatgatg gaagcctctt tgtatgacaa
     4261 aatcatggac caacagcgtc tggaacctga attcttcaga gttggatttt atgggaagaa
     4321 gtttccattt ttcttaagaa ataaggagtt tgtatgtcga gggcatgact acgaaagact
     4381 ggaggctttc caacagcgaa tgctgaacga gttcccccat gccatcgcca tgcagcacgc
     4441 caaccagcct gacgagacca tcttccaggc ggaagctcag tatttacaga tatatgctgt
     4501 gactcccatt ccagagagcc aggaggtgct gcagagagaa ggggttccgg acaacatcaa
     4561 aagcttctat aaagtgaatc acatctggaa gttccgctat gacagaccgt tccacaaagg
     4621 cacaaaagac aaggagaacg agttcaagag tctctgggtg gaaagaacat cgctgtactt
     4681 ggtgcagagc ttgcctggca tctcccgctg gttcgaagtg gaaaagcgtg aagtggtgga
     4741 aatgagtcct ctggaaaatg ccatcgaagt tttagaaaat aagaaccagc agctgaagac
     4801 cctgatcagc cagtgtcaga gcaggcaaat gcagaatatc aaccccttga ccatgtgcct
     4861 caacggagtc atagatgcag cggtgaatgg aggggtttcc aggtaccaag aggcgttctt
     4921 tgtcaaagac tatattttaa gtcatcctga agacggggag aagattgcac ggttaagaga
     4981 gctgatgctt gagcaggcac agattctgga atttgggctg gccgtgcatg agaaattcgt
     5041 acctcaagac atgaggcccc ttcacaaaaa actggtggac cagttctttg tgatgaaatc
     5101 gagcttcggg atacaggagt tccctgcctg tatccaggcc agccctgtcc attttcctaa
     5161 cggaagcccc cgtgtgtgta gaaactcagc ccctgcttcc atgagtccag atggtaccag
     5221 ggtaatccct agacgcagcc cattaagtta cccagctgtc aaccggtact cctcgtcctc
     5281 gctgtcctcc caggcctctg ctgaagtaag caatattaca gggcaatcag aaagctctga
     5341 tgaagtcttt aacatgcagc ccagcccatc tacctcaagc ctgagttcca ctcactctgc
     5401 ttcacctaat gtgacgagtt ctgctccgtc gagcgccaga gcttcacctc tgttgtctga
     5461 caaacacaaa cattccagag aaaactcttg cctgtccccg agagatagac cgtgcagtgc
     5521 catttaccca acgcctgtgg agccttccca gaggatgctg tttaatcata ttggagatgg
     5581 ggccttgcct cgcagtgacc ccaacctttc tgcacctgag aaagctgtga atcccacccc
     5641 tagcagttgg agcctggaca gtgggaaaga agccaagaac atgtcggaca gtgggaaact
     5701 tatctctccc cctgtccctc caaggcccac acagactgct tcgccagcaa gacacacaac
     5761 atccgtgtcc ccctcacctg ctggacggtc tccattgaag agctctgtac agtctttcac
     5821 cccatctcca gtggagtaca actccccagg actgagctcc aactccccag tcttgtccgg
     5881 cagctacagc agtggaatct cctcgcttag ccggtgtagc acttcagaaa cctccggctt
     5941 tgaaaaccaa gccaacgaac agtcggtgcc tgtgccggtg cccgtgcccg tgcccatgcc
     6001 agtgcccagc ttcagcgggt cggaggaacc tgtacgcaag gaaagcaaaa ccccgccccc
     6061 ctacagtgtc tacgagcgga ctctgcgacg ccctgtcccg ctacctcaca gcctctccat
     6121 ccctgtcacc tctgagccac ctgctctgcc ccccaagccc ttggcagcgc ggtccagcca
     6181 cctggagaat ggaacccgta ggactgagcc tggcccgagg cccaggcccc tgccccgcaa
     6241 ggtgtctcag ctctaagtca cttttctatg tacctgcgat gaattctttg ccgtttacaa
     6301 gttaagtctg atgagaagac atttatttag tgtaggcact ttaaatatct tactcagacc
     6361 tttctttaaa tgaatggaat taaatttgct tattaataat gttgcacaat attaaaagtt
     6421 actgatctaa aacgccagat gttacatgaa gtatggctga gtctcattaa aatgtttctc
     6481 atttgaaagt ggtaaattgt gaaaaagact ccttttgtac ctttttatgt tcactttttt
     6541 tacgtagttt aatcttaaag ccaatacaat attgtcaagc aataggatgt gtgatgatgt
     6601 tgtatacctt ttttttctga atacttgata ctctgagaaa gctgatcccg tctgtgcaca
     6661 tgctaacaca atggcccttt cttaagactt cagtaaagaa ggtgaccact ttggctctcc
     6721 ccttgagcag aaggttgagc acacatcctc agaattaaag gttaaagcag gctgttggtt
     6781 ggactagata cttaagggtt acaaggatcg ggactggaag ttgctttttt ttttttcttt
     6841 ctttctttct ttaagcaaaa tacttctttg aagtctgaca gctgtctaca tccttaactc
     6901 tgctttgtga atcggttgct aaatctttaa gtgccctgac accatgccat ctactgtatt
     6961 acttttcaag gtgcaatttg ctttcggagt tccaatcagc tagattaagc aaaagacccc
     7021 aggagaagtg tttacttgaa ttttgtgctt ccttacttga tgatttccta cacaaaacgt
     7081 gtcgctgatg aagagcatgt gtgcaaggtt taaaaagtca caaattactg tgtcccatta
     7141 acaaggattc aggaatcgat acaggacagt attaaatcaa tagcgtgaag gaagacaaaa
     7201 ccttagtgaa aatatattaa catgattgaa tggtaaaagg actttgaaaa ggtgagggca
     7261 ttaattttga atcctgcata aagtaattcc tcaaactctc ccttcttacc aagagagctg
     7321 agcacctctg ctcgtcctgt ggtccttttt ctgggcgagg aggattgtgg accattctag
     7381 catggataca gcaacatagc atcttaaatg gagatcgact agacgtgctg atgcgccagc
     7441 tgtaggagtg tgaaaaaagc accttgtatg tagtaatgta ttatttatct ctgtcttttc
     7501 tttttactga ctgtttataa cactcaattg acaatagcta tgaactgtat tttaaaccat
     7561 gctgttaaat attttccctc ttttgttggg aagctcattt tagtttagtt gtgtttggtt
     7621 tttctgttgc tagcttacct ggaaggcagt ggccacattt ttatattctc ttaatgaaac
     7681 cattcagcag gtatacgctg ttgaggctgg ttatagaggt tttctataat aaatgttcaa
     7741 gtatttttgt acataactgg ttaattttaa taagagatac cattatgtgt aaaaaaaaaa
     7801 agtaaaaagc aaacagttgt ggatgcagta tgattgttat aattatgcca aatactttat
     7861 gtatggaaac tatttgtaca tatgtgcttt taacaataat tctgccatat tgactttaca
     7921 attttgaatg tcaaaagatt aatatatgta aaaatattta tgtttagtga aagtattcat
     7981 attgaggaaa ggaacctatg aattttagct ttgtatcttg caggttttgc agttagaaat
     8041 ttctcaaact agcgtttgca tttgataata acactttgtg tttgtaatca catcctaaaa
     8101 agaaaaatat atatatatat atacatacat atacttatac atgtatgtag gaagctccat
     8161 gtttcttttg ctttaaagaa gtaaaatctt tcccttaagt aagatgatat gcataagata
     8221 acaaaacccc tttgatttcc gtttcctgtg taatttagta gattccttga ctagtgcttg
     8281 ggcacacaat aaatcagtgt tatttgctct tgaagccttt tctttttttc cttctttttt
     8341 tcttttttcg gcagtgaata gttgacttta tcatgtaagt gtatttctca agcagctatc
     8401 tagcagaaca ttttgagaga ttctgttagc tcagatgttc atgttgattg ctgctgaatg
     8461 gtaaatattg aataaagtta tcagattaat cttaa
//
