LOCUS       XM_039112664            9918 bp    mRNA    linear   ROD 22-FEB-2024
DEFINITION  PREDICTED: Rattus norvegicus DNA methyltransferase 3 alpha
            (Dnmt3a), transcript variant X3, mRNA.
ACCESSION   XM_039112664
VERSION     XM_039112664.1
DBLINK      BioProject: PRJNA1074393
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086024) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9918
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     gene            1..9918
                     /gene="Dnmt3a"
                     /note="DNA methyltransferase 3 alpha; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 16 ESTs, 395 long SRA reads, 31 Proteins"
                     /db_xref="GeneID:444984"
                     /db_xref="RGD:1303336"
     CDS             443..3169
                     /gene="Dnmt3a"
                     /codon_start=1
                     /product="DNA (cytosine-5)-methyltransferase 3A isoform
                     X1"
                     /protein_id="XP_038968592.1"
                     /db_xref="GeneID:444984"
                     /db_xref="RGD:1303336"
                     /translation="MPSSGPGDTSISSLEREDDRKEGEEQEENRGKEERQEPSATARK
                     VGRPGRKRKHPPVESSDTPKDPAVTTKSQPTAQDSGPSDLLPNGDLEKRSEPQPEEGS
                     PAAGQKGGAPAEGEGTETPPEASRAVENGCCVTKEGRGASAGEGKEQKQTNIESMKME
                     GSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIA
                     VMNAVEESQASGESQKVEEASPPAVQQPTDPASPTVATTPEPVGADAGDKNATKAADD
                     EPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSV
                     VCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPACHDSDESDTG
                     KAVEVQNKQMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPA
                     KKPRKSTTEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFIGG
                     MCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPG
                     AAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPA
                     EKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGD
                     VRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPK
                     EGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMN
                     RPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILW
                     CTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV"
     polyA_site      9918
                     /gene="Dnmt3a"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 cagcgacgga gggagggagc gcggcaggca gcgggcgggc cgggaggcgg cgcgggcggc
       61 ggcgcgagca gaggacgagc cgggacgcgg cgccgcggca gcagggcgag cggggccgcc
      121 cgacccgccg ggccacacga ctctgggagg tgccagacag tgtaacctgc ccatgccagc
      181 cagaggcatc tgacacctca ggtggcagaa gctatggaga ggcagcctcc tgatgggatg
      241 ggccccgtgt gattaataca gagtctgaaa aggcagagcc acccagcgct gaggcatcac
      301 tttccgaggg cttgacatca ggacctatgt ttaagtttta gctcttgctc acaaagacca
      361 cgataatacc ttctctgaag ccctcgcagt cccacagcgc cctcgaagcc ccagcctgcc
      421 tcctactgcc cagctgcccg caatgccctc cagcggcccc ggggacacca gcatctcctc
      481 tctggagcgg gaggatgatc gaaaggaagg agaggaacag gaggagaacc gtggtaagga
      541 agagcgtcag gagcccagcg ccacggcccg gaaagtgggg aggcctggcc ggaagcgcaa
      601 gcacccaccg gtggaaagca gtgacacccc caaggaccca gcggtgacca ccaagtctca
      661 gcccacagcc caggactctg ggccctcaga tctgctaccc aatggagact tggagaagcg
      721 gagtgaaccc caacctgagg aggggagccc agctgcaggg cagaagggtg gggccccagc
      781 tgaaggagag ggaactgaga ccccaccaga agcctccaga gcagtggaga atggctgctg
      841 cgtaaccaag gaaggccgtg gagcctctgc gggagagggc aaagaacaga agcagaccaa
      901 catcgaatcc atgaaaatgg agggctcccg gggccgactg cgtggtggct tggggtggga
      961 gtccagcctc cgtcagcggc ccatgccaag actcaccttc caggcagggg acccctacta
     1021 catcagcaaa cggaagcggg atgagtggct ggcacgttgg aaaagggagg ctgagaagaa
     1081 agccaaggtg attgcagtaa tgaatgctgt ggaggaaagc caggcctctg gggagtccca
     1141 gaaggtggag gaggccagcc ctcctgcagt gcagcagccc acggaccctg catctcccac
     1201 tgtggccacc acccctgagc cagtaggggc tgatgctggg gacaagaatg ctaccaaggc
     1261 agctgatgac gagcccgagt atgaggatgg ccggggcttt ggcattggag agctggtgtg
     1321 ggggaaactc cggggcttct cctggtggcc aggccgaatt gtgtcttggt ggatgacagg
     1381 ccggagccga gcagccgaag gcactcgctg ggtcatgtgg ttcggagatg gcaaattctc
     1441 agtggtgtgt gtcgagaagc tcatgcccct gagctccttc tgcagtgcgt tccaccaggc
     1501 cacctacaac aagcagccca tgtaccgcaa agccatctac gaagtcctcc aggtggccag
     1561 cagccgtgca gggaagctgt tcccagcatg tcatgacagc gatgaaagtg acactggcaa
     1621 ggctgtggag gtgcagaaca agcagatgat tgagtgggcc cttggcggct tccagccctc
     1681 tggtcccaaa ggcctggagc caccagaaga ggagaagaat ccttacaagg aagtttacac
     1741 cgacatgtgg gtggagcctg aggcagctgc ttatgcccca cccccaccag ccaagaaacc
     1801 cagaaagagc acaacagaga aacccaaggt caaggagatc attgatgaac gcacaagaga
     1861 acggctcgtg tatgaggtgc gccagaagtg ccgaaacatc gaggacattt gtatctcatg
     1921 tgggagcctc aatgttaccc tggagcaccc actcttcatt ggtggaatgt gccagaactg
     1981 taagaactgc ttcttggagt gtgcttacca atacgatgac gatgggtacc agtcctactg
     2041 taccatctgc tgtggggggc gcgaagtgct catgtgtggg aacaacaact gctgcaggtg
     2101 cttttgtgtg gagtgtgtgg atctcttggt ggggccaggg gctgcccaag cagccattaa
     2161 ggaagacccc tggaactgct acatgtgtgg gcacaagggc acgtatgggc tgctgcggag
     2221 acgggaggac tggccttctc gactccagat gttcttcgcc aataaccacg accaggaatt
     2281 tgaccccccg aaggtttacc cacctgtgcc agctgagaag aggaagccca tccgggtgct
     2341 atctctcttt gatgggattg ctacagggct cctggtgctg aaggacctgg gcatccaagt
     2401 ggaccgctac atcgcctccg aggtgtgcga ggactccatc acagtgggca tggtgcggca
     2461 ccagggaaag atcatgtacg tcggggacgt ccgcagcgtc acacagaagc atatccagga
     2521 gtggggccca ttcgatctgg tgattggggg cagtccctgc aatgacctct ccatcgtcaa
     2581 ccctgcccgc aagggacttt acgagggcac gggccgcctc ttctttgagt tctaccgcct
     2641 cctgcatgac gcgcggccca aggagggaga tgatcgcccc ttcttctggc tttttgagaa
     2701 tgtggtggcc atgggcgtta gtgacaagag ggacatctcg agatttcttg agtctaaccc
     2761 cgtgatgatc gacgccaaag aagtgtctgc tgcacacagg gcccgttatt tctggggtaa
     2821 ccttcctggc atgaacaggc cattggcatc cactgtgaat gataagctgg agttgcaaga
     2881 gtgtctggaa cacggcagaa tagccaagtt cagcaaagtg aggaccatta ccaccaggtc
     2941 aaactccata aagcagggca aagaccagca tttccctgtc ttcatgaatg agaaggaaga
     3001 catcctctgg tgcactgaaa tggaaagggt gtttggcttc cctgtccact acacagacgt
     3061 ctccaacatg agccgcttgg cgaggcagag actgctgggc cgatcgtgga gcgtgccagt
     3121 catccgccac ctcttcgctc cgctgaagga atattttgct tgtgtgtaag ggacatgggg
     3181 gcaaactgaa gtagtgatga taaccaagtt aaacaaacaa aaaaacaaaa cacaataaaa
     3241 caccaagaac gagaggacgg agagaagttc agcacccaga agagaaaaag gaatttaaag
     3301 caaaccacag aggaggaaat gccggagggc ttggccttgc agaagggttg gacatcatct
     3361 cttgagtttt caatgttcat cttcagtcct aactaaaacg caggataggc ccctcccctt
     3421 cctcccctcc ggtcctagga ggcgaacctt ttgttttcta ctcttttttt cagaggggtt
     3481 ttctgtttgt ttgggttttt gtttcttgct gtgactgaaa caagagagtt aattgcagca
     3541 aaatcagtaa caacaaaaag taatgccttg gagaggaaag ggagagaggg aaaattctat
     3601 aaaaacttaa aatattgttt tttttttttc cttttctata tatctctttg gttgtctcta
     3661 gcctgatcag ataggagcac aaacaggaac agaatagaga ccctcggagg cagagtctcc
     3721 tctcgcagcc cccgagcggt ctcaacagca ccatccctgg tcatgcagaa cagaacccaa
     3781 ctagcagcag ggcgctgaga ataccacacc agacactttt ctacagtatt tcaggtgcct
     3841 accacacagg aaaccttgaa gaaaaccagt ttctagaagc cgctgttacc tcttgtttac
     3901 agtttatata tatacgatag atatgagata tatatataaa aggtactgtt aactactgta
     3961 catcccaact tcataatggt gctttcaaaa cagcgagatg agcaaaaaca tcaacctcca
     4021 cctggccctc tgtgcaaagg gtttcagccc aggatggggg agggaagcag ctagagggtg
     4081 tcgttttttt tttttttttt tgtccctctt ggtttttaac aaaccaaagg aggaaccata
     4141 ttgcccccac ccccacccca ccccatgcct agcttctcct gccaaaagtg gggctcagct
     4201 gaggtggtcg gaacctgggg aagcggagtg tggaatttat ccagactcgc gtgcaataac
     4261 ctttgaatat gaatctaaaa cgactgcctc agaaaaatgg cttaaaaaaa aaaaaagttg
     4321 tccctgattt tgaatctgtc agccacattg aaggccccct tgtgggataa gaaataatcc
     4381 agagtgaggg aaagtgatcc gccattaacc ccacctggag caaataaaaa aacatacaaa
     4441 acgtactggt gctttctgtc taagttgcct tttgtgtgtt cttttatgag gccccccact
     4501 accccctgtg cacacggcag ctccggtcct ggaatgtgat gtttttggtc atctctaaag
     4561 actgcagttt catacttggg aggctgatga cacctttatt ataattattc ttatggttct
     4621 ggctataatt gttcatttta agattttctt tgagaaaaca aaaacccaac acccttccct
     4681 ttaggtttca aaccaaggtg caggggggtg gcaggtgctt ttttttcttt tctttttttt
     4741 taaggaccag tggctctggt gccctggctt ccacccctca ggccaggtgg gccactgggc
     4801 agtacagcac caagccaggc agccagggag ttccaaggcc cgccctccgg gccgtcattc
     4861 ttctcttctt ccctcctcgt gagtccggtg tgtcagggct ggagggaggc cggggcagcc
     4921 tctctccttg tgtgcgtggt tggagtggcg tgtgtttctt ttctagtgtt tggtccgata
     4981 gctgtgctct taccttgagt cagcttcacc tggggcctgt gcgctcacac tttgttctgc
     5041 ttcctaccca gggcagcctg gcattggccg tgggaaggga aggtgttgtt ggccccgggg
     5101 tgagggcttg tctggatgga tggagtgtag atatgtggca tatagagata tatattttat
     5161 aatgggaggg gggacggcac ctcctgagac cagcagaggc tgggaggtgt gctgtcaagc
     5221 acatggtccc gagaccgcat ccctagaaag atggggcctg tgataggccc tgtataaata
     5281 catagatagg gtcgtgtata agaaatttac acagtggggg ttggagggag caggctctgt
     5341 gttgagcctg ggtccctccc gcagacagcc ccacaaacag tatatcagtc tgacacatgc
     5401 acagggactt ctctctgtct ggatgcacac cagggagctc ccagcacact tctccccagg
     5461 gtcaggatgc tggagtcgct ctgcagctct cacacatctg ttgccctgat gacaggtaga
     5521 ctcgatccca gaagttgcta ggtgctgaag tcaggaaaag gaggaggttt gatccaagca
     5581 ggtgcttcct ctagcaggtc tgtgttctat accctttgcc cctggtgatg tcaaagattc
     5641 ttctgttagc agcctgtggt tactgacctg caactctagg caccagtcaa gtcagccctc
     5701 gactccccct acctattctc cccaaccaaa gtcgaactga aatctgtctt ggccattggt
     5761 cttccattgg gaacataaaa tattaaaaaa atttaaaatg ggacagtgta cctcactttt
     5821 ggagtaaagc aaatcattaa ttagtgttag aactaaacaa aggctttgtc cccttgctca
     5881 ctgctcagga gtaagcttag ctggtggctt ggtaacacct cttgggctgt gtggtcctgc
     5941 ccacctctgc tcattttctc tggatagttt taaaatgaca gctagttttc cctgccgtgg
     6001 caggtagtga ctatggggct ggggcatcca ggagagggga tgcttgccca cttggagtcc
     6061 ctatactaaa tgtgatagct cccctgctcc agcagggctc cattctgacc tggagtccac
     6121 cagcaccatg caggaggact ggaggggagg aaggctgctt taggcagtct aaggtgctcc
     6181 ctccccaact agcaatggca aggtcttccc agctcctgtc aggactgtct tcaaggtcct
     6241 cccacctctg cccactgctt atgtgaagaa gctagccttc cccaggagcc tcatgccacc
     6301 ccagctgggc ctggtgctcc ccaatgcctg gggttaatgt gagggctcag gaagaggggt
     6361 ctctgtcaat ggatgtggca ttctcaaggg actgagtaga ggctcccagg tggctggccg
     6421 atactgactt gacaagttcc ctaatagatt cccatggggc ctcttcacta gctttccttc
     6481 cagcccagtc ttaccatagt gtgtaggcac cagtccagtt agcccccaat atcttttggg
     6541 gaggtctttg tgactgcgcc tgcttggtct tcatccatct ctaccccaag tggggcttct
     6601 agggtcacct ccaaggagag ctcctaggat gctgtggtag ctgagcagag gctgtgggga
     6661 gttggcagag catgtaggag ctagttcact gtaggtggaa ttgaagctgg agtcaggtca
     6721 tgggatggga ggatccccaa aggttccccg cgggctttcc tttccaaaga atagtcttgt
     6781 ttcccctaga aactaaggtg ctgggggact gagtgacagc cacccctctg ctggtgctgt
     6841 gtgaagtctc acacccaaga tctgtgtgtg gcccttgcca ggggatgtag ctggtgctag
     6901 tgccagggtc acagaaccaa ggcctcctga ggaggcacac atgctagcgg ggtcccaagc
     6961 tggtgctaat tcctctccac aggacccaga agcctgggag cctgcagtaa gctgatccct
     7021 gctgtgaaca cccattagaa agccaaagtc ccacaggtag aaccacaggc ataaagaccc
     7081 ctgtggcttt tggcaaatga ccagaagtgt ggatgcagaa gcaacaggta gagttggtgg
     7141 cccttgcggg ccaacatcaa aagcatatac cttccccaat agcatctctg tactggagat
     7201 gctgtggtca tcacatgctg gtttaggaat tagtctgagc caccttgaag aaatgtgctc
     7261 acaagaagat acagattatt ggtttctcta tttactacgc agtttgtcca gagagtagaa
     7321 gcaaattccc gggcttgtcc ggttggtgca aagctgctgt gacactatag ggtcttcaga
     7381 accggtcact gtaggggtcc tggctgtgag ctgggacggt gtgaccattg cagctgtgtt
     7441 tccaagcagg cctgtgtttg tttgcatctg agcttggcac ttgtgatgag gtggccgtgc
     7501 tcacttgttc acttggcaga gaacagccga agcctgtcac cctgtgatgg tgtgtggagt
     7561 ttgtggccct tctgattggt cctgtcccat ccggtcggta cccatgctag gagcagtgct
     7621 ggttcggaag aacccccaag gaaaggactc gggttggtca gggtcattgt gagctcgcat
     7681 atgtttgtgt ggagaaagcc gaggtctttg ggaggaaagg ccttgtcctt tcaggcttcc
     7741 aagacaacag ctaaggttgg cctttggttg gagacaagtc tctaggccag acactggagt
     7801 ttcagcattg agaccaagag gtaggccaag atcgggatgt atggaaggcc gttgctggta
     7861 ggaaggcaca gcttctctag gggaccccag gaactcctgt aactggctct cccattggga
     7921 tgaaccccat ttgtgggctc ataaagcggc ctcctaactc cacccagtcc ccgagcctga
     7981 ggacatgagc agtggtctaa agtctcacct agtcccattt tacagactaa tttgattgtc
     8041 cggccctaga attctataga aacaacaata atgaaaagtt gaaattcctt agaatatgca
     8101 gagggagggg atgactcaca cggtgctaaa cacattttat taaaaatata tattgttaaa
     8161 ttaagtctgc tgtctggaca atgatgttct gttttgtttt cttgtagtgg agtttaaaag
     8221 agactattat tttactctga tatattatta ttaaaaaggc attttaactt tgtacttgaa
     8281 aactaagtga acgatttcac gtgttttagc tgaggcatcg aagtatcggg tgcttacttg
     8341 tgggaaatca tgtattcata ctacaaaata aactccgtgg ctggtttggt aataactttt
     8401 actgttacag acgatttcgc tttgaccccg gtggcagagc acttttactc cacattccac
     8461 gcagctaagt gcaggacctt ccagaacctt cccctagtcc ccctcggtcc tctttccgtt
     8521 cctcttccta tctctctctt ttcctatttt ttctttttaa attgtcgttt gttttccctg
     8581 gtcccagctt ccttctacca ctgtattttt ttgttagggt tgcttctcta tttattgaca
     8641 gtaatactgt acatttcaca gtctggttct ggggcagcca ggaggggtgt ggggggctgc
     8701 gcacagcttg ccgcaccatc cggtgtcccg ttgtatctct gtgtacgtga tgcttgtgac
     8761 atagctgttg aagaaataat taaaaaggtc aatgcgtaca gcaggtgtag acagtccgtc
     8821 agttccgctt tcatcacttt tctttttctt tttttttttt ttttttttgt gcccagaaga
     8881 atataataaa gctcctttct aatgtacttg tgctggagaa cacttgaata aatggactgt
     8941 ttttgtgcaa aaagaaaaat ggaaaacgaa aagcaccgtc ataatgtcct tttgtcctgc
     9001 gactcctttc ccctgatgtg acagctcgcg gtcctccagt gggctgaagt gggtgtgcat
     9061 aatatctggg gggcgtctgg ggaatggatt tctaacgcag ctctcgagtg ggtgttaact
     9121 aggggctggg acccaagggc agagggagtt tggctcaaga tcaaagagtc ggacaaagat
     9181 gaagttgtct ggttgacttc cagacacagc agatgtcttg agaccagaac aggaagcaga
     9241 tcagcatcct ggttaggtgg caggagaacc agtggggact taccgatgcc aggctcagaa
     9301 ggaagaagtg aggaaaggag ggagacagct gggccctggg ggaaccctag aagaacctcg
     9361 ggtttaaagg caatctttgc caacacgtga caggtaaccc aagggctggg gccagtggcc
     9421 aacaggctac tgctggtctg agtgtaggct ctctggcagg gccttatggc ctgaggtgtt
     9481 attgcccatg gtgtctctgt ctcacctttc tagaaggtca gtctgaatgc agagtctgtc
     9541 tgtcccccat atctccggga gtagccagta ggcttggcct gggtttccac tcctaaggat
     9601 tgttcaggct gtctcctccc ccaggctttt gggcgggttt gggatagcag acacactgtg
     9661 tggggatcct tgagcagatg gggaaagctc ggctagacag gttttctcat gggcactttt
     9721 tcttgctttt ttccctttga caaggttgta aatgtatatt tggcttttac tctacttctt
     9781 ttctcgatgt ttttcaatgt tgatgtggaa tcttactttc aaatggctgc atggtatttt
     9841 cttgttgaat gtttgtttat atatatttta ttttcgctat aaatagagct tcaataaaca
     9901 tctttatgtt ttggcttc
//
