LOCUS       NM_001134640            2357 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus DnaJ heat shock protein family (Hsp40) member C19
            (Dnajc19), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001134640 XM_578010
VERSION     NM_001134640.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2357)
  AUTHORS   Schulz,C., Schendzielorz,A. and Rehling,P.
  TITLE     Unlocking the presequence import pathway
  JOURNAL   Trends Cell Biol 25 (5), 265-275 (2015)
   PUBMED   25542066
  REMARK    Review article
REFERENCE   2  (bases 1 to 2357)
  AUTHORS   Sinha,D., Joshi,N., Chittoor,B., Samji,P. and D'Silva,P.
  TITLE     Role of Magmas in protein transport and human mitochondria
            biogenesis
  JOURNAL   Hum Mol Genet 19 (7), 1248-1262 (2010)
   PUBMED   20053669
REFERENCE   3  (bases 1 to 2357)
  AUTHORS   Elsner,S., Simian,D., Iosefson,O., Marom,M. and Azem,A.
  TITLE     The mitochondrial protein translocation motor: structural
            conservation between the human and yeast Tim14/Pam18-Tim16/Pam16
            co-chaperones
  JOURNAL   Int J Mol Sci 10 (5), 2041-2053 (2009)
   PUBMED   19564938
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2357)
  AUTHORS   Davey,K.M., Parboosingh,J.S., McLeod,D.R., Chan,A., Casey,R.,
            Ferreira,P., Snyder,F.F., Bridge,P.J. and Bernier,F.P.
  TITLE     Mutation of DNAJC19, a human homologue of yeast inner mitochondrial
            membrane co-chaperones, causes DCMA syndrome, a novel autosomal
            recessive Barth syndrome-like condition
  JOURNAL   J Med Genet 43 (5), 385-393 (2006)
   PUBMED   16055927
REFERENCE   5  (bases 1 to 2357)
  AUTHORS   Taylor,S.W., Fahy,E., Zhang,B., Glenn,G.M., Warnock,D.E., Wiley,S.,
            Murphy,A.N., Gaucher,S.P., Capaldi,R.A., Gibson,B.W. and Ghosh,S.S.
  TITLE     Characterization of the human heart mitochondrial proteome
  JOURNAL   Nat Biotechnol 21 (3), 281-286 (2003)
   PUBMED   12592411
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473961.1.
            
            On Sep 4, 2008 this sequence version replaced XM_578010.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM047437.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132307, SAMEA5756307
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2357
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q24"
     gene            1..2357
                     /gene="Dnajc19"
                     /gene_synonym="RGD1560220"
                     /note="DnaJ heat shock protein family (Hsp40) member C19"
                     /db_xref="GeneID:502525"
                     /db_xref="RGD:1560220"
     exon            1..137
                     /gene="Dnajc19"
                     /gene_synonym="RGD1560220"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..671
                     /gene="Dnajc19"
                     /gene_synonym="RGD1560220"
                     /note="DnaJ (Hsp40) homolog, subfamily C, member 19"
                     /codon_start=1
                     /product="mitochondrial import inner membrane translocase
                     subunit TIM14"
                     /protein_id="NP_001128112.1"
                     /db_xref="GeneID:502525"
                     /db_xref="RGD:1560220"
                     /translation="MASTVVAVGLTIAAAGFAGRYVLQAMKHVEPQVKQVFQSLPKSA
                     FSGGYYRGGFEPKMTKREAALILGVSPTANKGKIRDAHRRIMLLNHPDKGPLVEEGLK
                     PIPICRSCSSICRRSILSCSTSYNQNKDCFIHCVCLCAFMNAPMGTPVRHCETHLTHL
                     PQPTSSTGLTCFGLELEL"
     exon            138..189
                     /gene="Dnajc19"
                     /gene_synonym="RGD1560220"
                     /inference="alignment:Splign:2.1.0"
     exon            190..263
                     /gene="Dnajc19"
                     /gene_synonym="RGD1560220"
                     /inference="alignment:Splign:2.1.0"
     exon            264..343
                     /gene="Dnajc19"
                     /gene_synonym="RGD1560220"
                     /inference="alignment:Splign:2.1.0"
     exon            344..414
                     /gene="Dnajc19"
                     /gene_synonym="RGD1560220"
                     /inference="alignment:Splign:2.1.0"
     exon            415..2357
                     /gene="Dnajc19"
                     /gene_synonym="RGD1560220"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcccctgc cgtgttgcgc ggcgctgtgg aagtggcggc agtgctggct cggccctatc
       61 gttctactca agcgtactgt ggcggtgggc tcgcgctggg atgagcccgc ggtgccgagc
      121 cgcgaagtgg agtcatggcc agtacagtgg tagcagtcgg attgaccatt gctgctgcag
      181 gatttgcagg ccgttatgtt ttacaagcca tgaagcatgt ggagcctcaa gtaaaacaag
      241 tttttcagag tctaccaaaa tctgccttca gtggtgggta ctatagaggt gggtttgaac
      301 ccaaaatgac aaaacgggaa gcagcattaa tactaggtgt aagccctact gccaataaag
      361 ggaagatcag ggatgctcat cgacggatta tgctcttaaa ccacccagac aagggccctc
      421 tggtggaaga aggtctgaaa cccataccaa tctgtcgcag ctgttcatcg atctgcaggc
      481 gttccattct tagttgttcc acttcctaca atcaaaacaa agactgtttt atacactgtg
      541 tgtgtctatg tgcattcatg aatgcaccta tgggtacacc tgtcagacac tgtgagaccc
      601 acttgaccca tcttccccag cccacatcct ctacaggttt gacatgtttt ggactagagc
      661 tagaactgta gagtatacac caaagaaaca aactgtgatc ttttgaaatc atctcataaa
      721 gcagaactgt attcacgagg tcatttgggg gtcaactcaa gaaacactga aagctttttg
      781 ctataagcaa acagtataat tctttcaagt aactgttcta ttgcagtaac ttatctgtta
      841 ttgttatcta atattaccaa atactgtcct ttttttgctt ttgagtgcat gtgtatacat
      901 gcgcatataa gtttatatat accatcatgc acctgtggag atctaactgt aacttgaagt
      961 agttgattct ctcctacaat gtgagtttta tgtatgtatg taagcttagc tgcaaaaact
     1021 ttaatgcacg gagtcagccc actggccaaa tactgtctct ttaaaaaggg agttaaatat
     1081 tctattaaag gtattattaa caagctattt cacgagcaac attttcattt atgactgaga
     1141 tagacaagct gatctgatca tttagaaact gaggtcctgc aacagtgaag gtatccaatc
     1201 taaagagtta tctgctggga ctacagaaga taaaaaagca tttgcttaca aggccaggat
     1261 tgataaaatt ccaagaaatt gaatggtgtt atcaaatgtg ctttcaaatt gcttgtacaa
     1321 gaataatatc agaatacaag gaaaatatac tatgaataga gagcaggtta ggattattac
     1381 tggaactatg aacaacaaaa aaagaagaga aaaacaaaaa actgacgctt actggtagtc
     1441 acttttttct ataatccttg tgtattatat ttcaaccgaa attaacaaat gggggctgag
     1501 gatagaacac agaaactgat gcctgttttg tttaccgtgc ccttggctct ggtttgcatc
     1561 ttcagcaact cacccttccc tcaaaattga tggaatgcag tgtactgggg caaggacgct
     1621 agctcacata ataccagggt tatcaaagaa acccaatttc acctgtgtag atggctaaaa
     1681 ctcaaaaaca gaaacaaaat ggccctagta gagcacataa ttattgtaaa caatgaactc
     1741 ttcaaacgtg aagagtttga agtcttcaaa cgtgaagtct ttgggggggg gggtaaagac
     1801 tctaccaccc cttacaaaag tgttaagggc aaagaacatg ttactctcaa gttaacaaaa
     1861 acagggcaaa acttaattaa aatatttaat tacccaaaaa cattaccata acaaacaaga
     1921 acgttcaacc tgcagacacc ttgtttatac taggtataca acattgacag agaaaatgca
     1981 gcagaatgat acatgacaaa gtgagctgtg cccatacctt taagtaagca atgtgatact
     2041 ctagaagaac ttgcacattt ccaatacttt ctttagtgcc aacaaataca aatggaacca
     2101 ttccctgtaa gaaaacataa gttcctcaat ttttttagag atttttcaat gtcttacttg
     2161 tactaaaatt tacatttcag tttgctaaaa aaaaaaaaaa aaaagtatca gtttgtgcta
     2221 gttttctgga ttttaatcaa tgtaatgtcc caagaataca aaccactttt taagcaaaat
     2281 actcaaaata ctctttcaga ctagaaaaat tatcatagta ggcacagcta gaaaataatg
     2341 aaataatgaa aagaaag
//
