LOCUS       NM_012699               1927 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus DnaJ heat shock protein family (Hsp40) member B9
            (Dnajb9), mRNA.
ACCESSION   NM_012699
VERSION     NM_012699.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1927)
  AUTHORS   Fritz,J.M. and Weaver,T.E.
  TITLE     The BiP cochaperone ERdj4 is required for B cell development and
            function
  JOURNAL   PLoS One 9 (9), e107473 (2014)
   PUBMED   25222125
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1927)
  AUTHORS   Lai,C.W., Otero,J.H., Hendershot,L.M. and Snapp,E.
  TITLE     ERdj4 protein is a soluble endoplasmic reticulum (ER) DnaJ family
            protein that interacts with ER-associated degradation machinery
  JOURNAL   J Biol Chem 287 (11), 7969-7978 (2012)
   PUBMED   22267725
REFERENCE   3  (bases 1 to 1927)
  AUTHORS   Hageman,J., van Waarde,M.A., Zylicz,A., Walerych,D. and
            Kampinga,H.H.
  TITLE     The diverse members of the mammalian HSP70 machine show distinct
            chaperone-like activities
  JOURNAL   Biochem J 435 (1), 127-142 (2011)
   PUBMED   21231916
REFERENCE   4  (bases 1 to 1927)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   5  (bases 1 to 1927)
  AUTHORS   Dong,M., Bridges,J.P., Apsley,K., Xu,Y. and Weaver,T.E.
  TITLE     ERdj4 and ERdj5 are required for endoplasmic reticulum-associated
            protein degradation of misfolded surfactant protein C
  JOURNAL   Mol Biol Cell 19 (6), 2620-2630 (2008)
   PUBMED   18400946
REFERENCE   6  (bases 1 to 1927)
  AUTHORS   Berger,B.J., Muller,T.S., Buschmann,I.R., Peters,K., Kirsch,M.,
            Christ,B. and Prols,F.
  TITLE     High levels of the molecular chaperone Mdg1/ERdj4 reflect the
            activation state of endothelial cells
  JOURNAL   Exp Cell Res 290 (1), 82-92 (2003)
   PUBMED   14516790
REFERENCE   7  (bases 1 to 1927)
  AUTHORS   Shen,Y., Meunier,L. and Hendershot,L.M.
  TITLE     Identification and characterization of a novel endoplasmic
            reticulum (ER) DnaJ homologue, which stimulates ATPase activity of
            BiP in vitro and is induced by ER stress
  JOURNAL   J Biol Chem 277 (18), 15947-15956 (2002)
   PUBMED   11836248
REFERENCE   8  (bases 1 to 1927)
  AUTHORS   Prols,F., Mayer,M.P., Renner,O., Czarnecki,P.G., Ast,M.,
            Gassler,C., Wilting,J., Kurz,H. and Christ,B.
  TITLE     Upregulation of the cochaperone Mdg1 in endothelial cells is
            induced by stress and during in vitro angiogenesis
  JOURNAL   Exp Cell Res 269 (1), 42-53 (2001)
   PUBMED   11525638
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Nov 26, 2020 this sequence version replaced NM_012699.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X98993.2, BC070915.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840129, SAMN16676786
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-168               JAXUCZ010000006.1  67001884-67002051   c
            169-395             JAXUCZ010000006.1  67000105-67000331   c
            396-1927            JAXUCZ010000006.1  66997842-66999373   c
FEATURES             Location/Qualifiers
     source          1..1927
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q21"
     gene            1..1927
                     /gene="Dnajb9"
                     /gene_synonym="ERdj4; Mdg1"
                     /note="DnaJ heat shock protein family (Hsp40) member B9"
                     /db_xref="GeneID:24908"
                     /db_xref="RGD:3070"
     exon            1..168
                     /gene="Dnajb9"
                     /gene_synonym="ERdj4; Mdg1"
                     /inference="alignment:Splign:2.1.0"
     exon            169..395
                     /gene="Dnajb9"
                     /gene_synonym="ERdj4; Mdg1"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..847
                     /gene="Dnajb9"
                     /gene_synonym="ERdj4; Mdg1"
                     /note="mdg-1; microvascular endothelial differentiation
                     gene 1 protein; dnaJ homolog, subfamily b, member 9; DnaJ
                     (Hsp40) homolog, subfamily B, member 9; ER-resident
                     protein ERdj4; endoplasmic reticulum DNA J
                     domain-containing protein 4"
                     /codon_start=1
                     /product="dnaJ homolog subfamily B member 9 precursor"
                     /protein_id="NP_036831.2"
                     /db_xref="GeneID:24908"
                     /db_xref="RGD:3070"
                     /translation="MATPQSVFVFAICILMITELILASKNYYDILGVPKSASERQIKK
                     AFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDIIGHSAFTNGKGQRS
                     NGSPFEQSFNFNFDDLFKDFNLFGQNQNTRSKKHFENHFQTRQDGSSRQRHHFQEFSF
                     GGGLFDDMFEDMEKMFSFSGFDSTNRRTVQTENRFHGSSKHCRTVTQRRGNMVTTYTD
                     CSGQ"
     exon            396..1927
                     /gene="Dnajb9"
                     /gene_synonym="ERdj4; Mdg1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccagtagtg agcgggccga acaggacgaa ggttgctcgg ctgttagagg cgaggtcgga
       61 gcgtgtgcgg cgagggtgag ggagccggag ccggagccgg agccggagcc ggagccggag
      121 ccggagccgg gccgccgcgg tttggagaag ctgcgtcggg gcgcacgggt tattagaaat
      181 ggcaactcca cagtcagttt tcgtctttgc catctgcatt ctaatgataa cagaattaat
      241 cctggcctca aaaaactact atgatatctt aggtgtgcca aagtcagcct cagagagaca
      301 aatcaaaaag gcctttcaca aattagccat gaagtaccac cctgataaaa ataaaagccc
      361 tgatgctgaa gcaaaattca gagagattgc agaagcatat gaaacactct cggatgccaa
      421 tagacggaaa gagtatgata taattggaca cagtgctttt actaatggca aaggacaaag
      481 aagcaatgga agtccttttg agcagtcatt taacttcaat tttgatgact tatttaaaga
      541 ctttaatttg tttggtcaga accagaacac tcggtctaag aagcattttg aaaatcactt
      601 ccagacacgc caggatggtt ccagtagaca aaggcatcac ttccaggagt tttcttttgg
      661 aggtggattg tttgatgata tgtttgaaga catggagaag atgttttctt ttagtggctt
      721 tgatagcacc aatcgacgca cagtacagac tgaaaataga tttcatggat ccagcaagca
      781 ctgcaggacc gtcactcagc ggagagggaa tatggttact acgtacaccg actgttcagg
      841 acagtagttg gatcttttcc tgtgtccact aagcccacct agtttactct tcctcactat
      901 gtctgatgaa aaaagttttc tgtgaactag tttggcatga tttcacttat gttaagcagt
      961 ttgttattag gtatttcata tattgaaatt tttttttttt tttaacaaaa cacattcagc
     1021 tagtaaacaa ttctaatttt cctgattagg aaaagttctt ttgaaagatc atttgaaaga
     1081 tagattttcc tctttacctg tcctttggct cattaatttg cccctccctc ccccaacaaa
     1141 aaaagaaaat cccaaacaac tcagttagcc caacatactt aatgattaaa taatgattaa
     1201 attttaagtt atcatagatt tgcattgtat gaacttgaat aatatttgca gtgaaacctc
     1261 tgggaactta aaactacaca gcctatggtc cctgtaactc gggctactaa atgtatatga
     1321 agctgtaatt gagtcattta gtgaagacca ccattgtttt tggctctttg ccactgaaag
     1381 ctttagaaag tgatggtttg atgtctatca cagaaagatt cctcttctac aggagaattg
     1441 gtgtgatggg gatgattgta ttgcacgtag ttaagctgaa gaaagtttaa aatttataaa
     1501 ctattgccaa gaaattgtgt tttagtaatg ggctaatgat tttgtatgat caaaatcata
     1561 gctttgtaaa cttctttttg aatatttttg tttgttgact ttctaggtct tcgtatgaat
     1621 ttgttttttg tttttggtgt gtgtgtgtgt agttactctg ttgcacttat ctttatctag
     1681 agattgacta atacctcatt ctttttgtaa aagcagccag taatttctgt gcaaccttac
     1741 tatgtgcaat atttttaaat tttaagaaac gtgtgcttct tttgttgtta gagttatttc
     1801 tttagttctg cacttttcca tgttatactc catatgagta ttaatcctat ggatgcatat
     1861 gaaaactagt aatgtctcat acaatattgt gtgtgagtga gagaaactat aaatatttac
     1921 aacctga
//
