LOCUS       NM_001415952            3391 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus DnaJ heat shock protein family (Hsp40) member B5
            (Dnajb5), transcript variant 1, mRNA.
ACCESSION   NM_001415952 XM_039110129
VERSION     NM_001415952.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3391)
  AUTHORS   Hageman,J., van Waarde,M.A., Zylicz,A., Walerych,D. and
            Kampinga,H.H.
  TITLE     The diverse members of the mammalian HSP70 machine show distinct
            chaperone-like activities
  JOURNAL   Biochem J 435 (1), 127-142 (2011)
   PUBMED   21231916
REFERENCE   2  (bases 1 to 3391)
  AUTHORS   Ago,T., Liu,T., Zhai,P., Chen,W., Li,H., Molkentin,J.D.,
            Vatner,S.F. and Sadoshima,J.
  TITLE     A redox-dependent pathway for regulating class II HDACs and cardiac
            hypertrophy
  JOURNAL   Cell 133 (6), 978-993 (2008)
   PUBMED   18555775
REFERENCE   3  (bases 1 to 3391)
  AUTHORS   Chen,M.S., Roti,J.R. and Laszlo,A.
  TITLE     Hsc40, a new member of the hsp40 family, exhibits similar
            expression profile to that of hsc70 in mammalian cells
  JOURNAL   Gene 238 (2), 333-341 (1999)
   PUBMED   10570961
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jan 6, 2023 this sequence version replaced XM_039110129.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.27039.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760475
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-87                JAXUCZ010000005.1  61972706-61972792
            88-555              JAXUCZ010000005.1  61973266-61973733
            556-800             JAXUCZ010000005.1  61975904-61976148
            801-1402            JAXUCZ010000005.1  61979089-61979690
            1403-3391           JAXUCZ010000005.1  61979899-61981887
FEATURES             Location/Qualifiers
     source          1..3391
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..3391
                     /gene="Dnajb5"
                     /note="DnaJ heat shock protein family (Hsp40) member B5"
                     /db_xref="GeneID:313811"
                     /db_xref="RGD:1307453"
     exon            1..87
                     /gene="Dnajb5"
                     /inference="alignment:Splign:2.1.0"
     exon            88..555
                     /gene="Dnajb5"
                     /inference="alignment:Splign:2.1.0"
     CDS             374..1636
                     /gene="Dnajb5"
                     /note="isoform 1 is encoded by transcript variant 1; dnaJ
                     homolog subfamily B member 5; DnaJ (Hsp40) homolog,
                     subfamily B, member 5; heat shock cognate 40"
                     /codon_start=1
                     /product="dnaJ homolog subfamily B member 5 isoform 1"
                     /protein_id="NP_001402881.1"
                     /db_xref="GeneID:313811"
                     /db_xref="RGD:1307453"
                     /translation="MFKRTVLSCPPPAAPPLQARGAFRSFPHFWGEDFLASLMFKIQL
                     EPLKLRAWTLNGFVKFRNKEPSTGPVAVMGKDYYKILGIPSGANEDEIKKAYRKMALK
                     YHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRSLYDQYGEEGLKTGGGTSGGSGGSFHY
                     TFHGDPHATFASFFGGSNPFDIFFASSRSTRPFSGFDPDDMDVDEDEDPFGAFGRFGF
                     NGLSRGPRRAPEPLYPRRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTV
                     RTEDKILHIVIKRGWKEGTKITFPKEGDATPDNIPADIVFVLKDKPHAHFRRDGTNVL
                     YSALISLKEALCGCTVNIPTIDGRVIPLPCNDVIKPGTVKRLRGEGLPFPKVPTQRGD
                     LIVEFKVRFPDRLTPQTRQILKQHLPCS"
     exon            556..800
                     /gene="Dnajb5"
                     /inference="alignment:Splign:2.1.0"
     exon            801..1402
                     /gene="Dnajb5"
                     /inference="alignment:Splign:2.1.0"
     exon            1403..3391
                     /gene="Dnajb5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcccgagtg gaggcggcgg agccggagcc gggggagggg gcagcggctg atagaaggac
       61 cgcggcggcg cccgcagctc ctcaccggta cacacgctgc cactcaacaa ctacacacag
      121 tcacttccgg cctcactgtc acacagccgt ccaggcgctc acaccattca gccagacact
      181 gctgtacccg agagcaggtg gccactggac cctctcactg cactctacac ctggggatca
      241 ggtccagctt ctggggcacg agacaggcct tgctgggcca cggcctgtgg gaatctgagg
      301 aggtggcttc cagagctaca gcgtcccagg caggctccgg tggagcgatc agaggtgagg
      361 ggcttggctg ggcatgttta agcgcacagt gctgtcctgc ccacccccag cagcaccccc
      421 actgcaggct cgaggagctt tccggagctt cccacacttc tggggagaag acttcttagc
      481 cagcttgatg tttaaaattc agctggagcc cttaaaactt cgagcgtgga cgctgaatgg
      541 gtttgtaaag tttcgaaaca aggagcccag caccggtcca gtggctgtga tgggaaaaga
      601 ttattacaag attcttggaa tcccgtctgg ggccaacgaa gatgagatca agaaagccta
      661 tcgaaagatg gccttgaagt accacccaga caagaacaaa gaacccaacg ctgaggagaa
      721 gtttaaggag attgccgagg cctacgacgt gctgagtgac cctaagaaac ggagcctgta
      781 tgaccagtat ggggaggaag gcctcaagac cggcggtggt acctcaggtg gctccggtgg
      841 ctcctttcac tacacctttc acggggaccc tcatgccacc tttgcttcct tctttggtgg
      901 ctccaacccc ttcgatatct tctttgccag cagccgctcc actcggcctt tcagtggctt
      961 tgacccagat gacatggatg tggatgaaga tgaggaccca tttggtgcct ttggccgctt
     1021 tggcttcaat gggctgagta ggggtccgag gcgagcccca gaaccactgt acccccggcg
     1081 caaggtacag gacccccctg tggtgcatga gctgcgggtg tccctggagg agatctacca
     1141 cggctccacc aagcgcatga agatcacaag gcgacgcctt aaccccgatg ggcgaactgt
     1201 gcgcaccgag gacaaaatcc tgcacattgt catcaaacgt ggctggaagg agggcaccaa
     1261 gattaccttc cccaaagagg gcgatgccac acccgacaac atcccagccg acattgtctt
     1321 cgtgctcaaa gacaagcctc atgcgcactt tcgccgagat ggcaccaacg tgctctacag
     1381 tgcactcatc agcctcaagg aggcgctgtg tggctgcacc gtgaacattc ccaccattga
     1441 tggccgagtg atccctttac cctgcaatga tgttattaaa ccaggcaccg tgaagagact
     1501 ccgtggggag ggacttccct tccccaaggt gcccactcag cggggagacc tcattgttga
     1561 gttcaaagtt cgattcccag acagattaac cccacagaca cggcagatcc ttaaacagca
     1621 cctaccctgc tcctaggctc tccctagcct gtctggagcc caccacagca atacccccac
     1681 actcaccaat ctcatgtgga cccggctgga tgtccaccgg acactggcac tttcctaaaa
     1741 tgcaagaagc cactgatttt caggaaaatg ttcctcttcc cgacaacccc tttcggagct
     1801 gggctgcttt gggggaatgg gagggcggtg gggagaacta gcccagacca ggggtcaatt
     1861 tttttgtcac gtgctttgaa tccagttccc actgcagtgg ctggagagtg acttgagagc
     1921 tactcggagc tatagattcc ttgtcctgcc tgtaaatagc atgtcctccc ccttctcagc
     1981 cttgctaaca cctttcctct cccttcccct cggcttcctc ctgtttctgg agaaagaagt
     2041 tagaaaggac accgcttccc accccacccc caggtctgta gtgtccgagg ctattttgca
     2101 caagtgttcg tgcacatgaa gcactcgcca aaatggtccg tgtctctctg agagacaaga
     2161 aaggacagga ggtaggaagg tcccttaccg atgaacaagg ctgtcatttg agcacgagac
     2221 acttttcatt tggggcaggg aggtgagcca acccttagga gccttcccaa cagctgccct
     2281 gcctacaccc cacagagttg gaggatctgt ccccctcagc tgctctgggg agtgttcagg
     2341 ggtggagaga agaaaggagg gcctgaacca tccaccacag ctaagaggtg gggcaggacc
     2401 catctcccag ccatcaccag gaaggaaaag ggctttggga tcaggtggca gctgttcccc
     2461 accaagagat tcaggatcac aggttccttc ccatatctct gaactcaggg cctagccacc
     2521 ccaaacttcc aagccccact tttgcgatat gtgaagctac ttatttctta cttttcttgg
     2581 aggctgtgtc ggaaatttcc agcctctctg cctgtgtgac cctcacccca ccccactccc
     2641 acagttgtat aaaagtcgaa tagtgaagga gctgggagaa aactgcttca gttggtcctg
     2701 gggtggggtc tttaggtttt ctcactttga caagcccctg aatgttttta tagtagtttt
     2761 ttgtattttt ttgtaatgac agtattatga aaaaaataaa gtattttaaa aatatggcct
     2821 ctgagcagaa gcagtaaccc tgggtgcagg caggaataaa gtggcactgt cagcctcctt
     2881 cagggccctg atcatccagg aaagccaagc agcctcagca gctgacgctc accccttctc
     2941 cctgtaagct ctgacttctt ggaattctgg aacatatacc ccaaacaaac agcaacacca
     3001 gaagccacag cccagctgtc tgcgaagaaa gatgggcctt tgttgtgaga gagagcctgg
     3061 cctcttcaga agcttgtcaa catgagatct agcacacttg tctcggtgtt ctctttgaat
     3121 tagagacact ttattccttg gaggagattg aggactctct gactagcgag actaggcaca
     3181 ctcccaaaaa cagagttggg ctaccaagtg ggctggagag atggttcagc agttaagagc
     3241 acttcctgtt ctcacagaga agccaaattc agttcccagg acacatcagg cagctcgaga
     3301 ctgctcaagg gaatccaaca agtccagcct cacaaagaat ctgcacccat gcacacacac
     3361 acttacaaaa aataaaaagt ttttttaaaa a
//
