LOCUS       NM_001005885            2280 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus DnaJ heat shock protein family (Hsp40) member B13
            (Dnajb13), mRNA.
ACCESSION   NM_001005885 XM_218960
VERSION     NM_001005885.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2280)
  AUTHORS   Shang Y, Yan J, Tang W, Liu C, Xiao S, Guo Y, Yuan L, Chen L, Jiang
            H, Guo X, Qiao J and Li W.
  TITLE     Mechanistic insights into acephalic spermatozoa syndrome-associated
            mutations in the human SUN5 gene
  JOURNAL   J Biol Chem 293 (7), 2395-2407 (2018)
   PUBMED   29298896
REFERENCE   2  (bases 1 to 2280)
  AUTHORS   Shang Y, Zhu F, Wang L, Ouyang YC, Dong MZ, Liu C, Zhao H, Cui X,
            Ma D, Zhang Z, Yang X, Guo Y, Liu F, Yuan L, Gao F, Guo X, Sun QY,
            Cao Y and Li W.
  TITLE     Essential role for SUN5 in anchoring sperm head to the tail
  JOURNAL   Elife 6, e28199 (2017)
   PUBMED   28945193
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2280)
  AUTHORS   El Khouri E, Thomas L, Jeanson L, Bequignon E, Vallette B,
            Duquesnoy P, Montantin G, Copin B, Dastot-Le Moal F, Blanchon S,
            Papon JF, Lores P, Yuan L, Collot N, Tissier S, Faucon C, Gacon G,
            Patrat C, Wolf JP, Dulioust E, Crestani B, Escudier E, Coste A,
            Legendre M, Toure A and Amselem S.
  TITLE     Mutations in DNAJB13, Encoding an HSP40 Family Member, Cause
            Primary Ciliary Dyskinesia and Male Infertility
  JOURNAL   Am J Hum Genet 99 (2), 489-500 (2016)
   PUBMED   27486783
REFERENCE   4  (bases 1 to 2280)
  AUTHORS   Li W and Liu G.
  TITLE     DNAJB13, a type II HSP40 family member, localizes to the spermatids
            and spermatozoa during mouse spermatogenesis
  JOURNAL   BMC Dev Biol 14, 38 (2014)
   PUBMED   25233908
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2280)
  AUTHORS   Guan J and Yuan L.
  TITLE     A heat-shock protein 40, DNAJB13, is an axoneme-associated
            component in mouse spermatozoa
  JOURNAL   Mol Reprod Dev 75 (9), 1379-1386 (2008)
   PUBMED   18247331
REFERENCE   6  (bases 1 to 2280)
  AUTHORS   Yang HM, Liu G, Nie ZY, Nie DS, Deng Y and Lu GX.
  TITLE     Molecular cloning of a novel rat gene Tsarg1, a member of the
            DnaJ/HSP40 protein family
  JOURNAL   DNA Seq 16 (3), 166-172 (2005)
   PUBMED   16147871
  REMARK    GeneRIF: Tsarg1 is specifically expressed in rat testis, which
            probably inhibits rat testis spermatogenic cell apoptosis
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC098002.1.
            
            On Jun 19, 2005 this sequence version replaced NM_001005885.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098002.1, AY325765.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2280
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..2280
                     /gene="Dnajb13"
                     /gene_synonym="Tsarg1"
                     /note="DnaJ heat shock protein family (Hsp40) member B13"
                     /db_xref="GeneID:308857"
                     /db_xref="RGD:1359131"
     exon            1..74
                     /gene="Dnajb13"
                     /gene_synonym="Tsarg1"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..957
                     /gene="Dnajb13"
                     /gene_synonym="Tsarg1"
                     /note="testis spermatogenesis apoptosis-related protein 6;
                     testis spermatogenesis apoptosis-related protein 1; DnaJ
                     (Hsp40) related, subfamily B, member 13; DnaJ (Hsp40)
                     homolog, subfamily B, member 13"
                     /codon_start=1
                     /product="dnaJ homolog subfamily B member 13"
                     /protein_id="NP_001005885.1"
                     /db_xref="GeneID:308857"
                     /db_xref="RGD:1359131"
                     /translation="MGMDYYAVLQVNRNSEDAQIKKAYRKLALKNHPLKSNEPTAPEI
                     FRQIAEAYDVLSDPVKRGIYDKFGEEGLKGGIPLEFGSQTPWTTGYVFHGNPEKVFHE
                     FFGGDNPFSEFFDAEGNDIDLNFGGLRGRGVQKQDPPIERDLYLSLEDLFFGCTKKIK
                     ISRRVLNEDGYSSTIKDKILTIDVRPGWRQGTRITFEKEGDQGPNIIPADIIFIVKEK
                     LHPRFRREQDNLFFVYPIPLGKALTCCTVEVKTLDDRLLNIPINDIVHPKYFKMVPGE
                     GMPLPEDPTKKGDLFIFFDIQFPTRLTPQKKQMLRQALLT"
     exon            75..178
                     /gene="Dnajb13"
                     /gene_synonym="Tsarg1"
                     /inference="alignment:Splign:2.1.0"
     exon            179..340
                     /gene="Dnajb13"
                     /gene_synonym="Tsarg1"
                     /inference="alignment:Splign:2.1.0"
     exon            341..498
                     /gene="Dnajb13"
                     /gene_synonym="Tsarg1"
                     /inference="alignment:Splign:2.1.0"
     exon            499..612
                     /gene="Dnajb13"
                     /gene_synonym="Tsarg1"
                     /inference="alignment:Splign:2.1.0"
     exon            613..726
                     /gene="Dnajb13"
                     /gene_synonym="Tsarg1"
                     /inference="alignment:Splign:2.1.0"
     exon            727..803
                     /gene="Dnajb13"
                     /gene_synonym="Tsarg1"
                     /inference="alignment:Splign:2.1.0"
     exon            804..2261
                     /gene="Dnajb13"
                     /gene_synonym="Tsarg1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccagccatgg ggatggatta ctatgctgtg ctccaggtca atcgcaactc agaggatgcc
       61 cagatcaaga aggcataccg gaagcttgcc ctgaagaacc acccattaaa gtcaaatgag
      121 ccgactgcac cagaaatatt caggcaaata gcagaagcct acgacgtgct gagcgaccca
      181 gtgaaacgag gcatctatga caagtttggc gaggaaggcc tgaagggtgg gattcctctg
      241 gagtttggat cccagactcc atggacaacg ggctatgtct tccatggcaa ccctgaaaaa
      301 gtgttccacg agttttttgg aggagacaac cccttcagtg aattttttga tgcagaagga
      361 aatgatatag atttgaattt tggggggctt cggggccgag gggtccagaa acaagaccct
      421 ccaattgaac gagacctcta tttgtccctg gaggacttat tctttggctg caccaaaaaa
      481 attaagatct cccgaagggt gctaaatgaa gatgggtatt cctctaccat caaggacaag
      541 atcctgacca tcgatgtgag gcctgggtgg aggcagggca cgcgcatcac ctttgagaag
      601 gaaggggacc agggccccaa cattatcccg gccgatatta tcttcatcgt aaaggagaag
      661 ctgcaccctc gcttccgcag ggagcaggac aacctcttct ttgtgtaccc cattcctttg
      721 ggcaaggccc ttacctgctg cactgtggag gtgaagaccc ttgatgaccg gctgctcaac
      781 atccccatca acgacattgt ccaccccaag tacttcaaga tggtgccagg tgaggggatg
      841 ccgctgcctg aggaccccac caagaaggga gacctcttca tcttcttcga catccagttc
      901 cccacccgtc tcacacccca gaagaagcag atgctgcgcc aggcactgct gacctaattc
      961 cgggggacct gagcaggaac agggatggag agggctagct gggccttgcc cgctcctacc
     1021 ccctcagccc ccacagcctg tgaagatggg gaagcacgag atcttaggct gacataataa
     1081 agattccttt cctatcctct aactatgacg ggaagcgagt cggggggatg ttacctctag
     1141 gaaccaaaaa gctaggcacc tggggcccca ttttggcttc ctaggcatgg acttgttcac
     1201 tgagacttca gagtctcttg caacaccaga cagggctgtg tgacctccag ggtccttctg
     1261 tcttgacgtc tcacaacata tatctttaga ggaaccatct gtggactgtg ctgtcttgag
     1321 aactacggac agggaaagtg aagcacagga agaggcagcg gctgtcccgg cgctcctgtg
     1381 tccgtggcta agcagccatc agaaccctag gccactccat ctaggctcac aagcttcagt
     1441 taagagccac acccacagca cagtgccaga agggctctgg cctccacctc tgctttggtt
     1501 cctcgtctat gaaatgagtt ttaagctgcc tctgggccag cagtctggga ggcatgggcc
     1561 cttgacgacc tgactcttga ccttgttgtc aagactactg accttgttgg tgaagcttac
     1621 aacctgccta caggtagaag actggggtca ttggtgtgaa aacgctcatg gttagattat
     1681 agagagccac ggcatcattg cccggtgacc tggaggaggt ccagcttctg ggtccacacc
     1741 cacgccttta aggtcaacaa tgctgtgttc ctcttccttg ctaaggtgct tgccctgtct
     1801 ggggtttgag tttaggctgt gattaggtct agggttgtgg gcatcaagca ggttcggtgg
     1861 tttctaagat atgaaaacaa cccagactgt ccacattgct tagaattctg tcactcaaat
     1921 cgccacatta gcttaaggct tttccctttt gtctttaaaa aaaatctttt ggggctgggg
     1981 atttagctca gtggtagagc gcttacctag gaagcgcaag gccctgggtt cagtccccag
     2041 ctccgaaaaa aaaaagaacc aaaaaaaata aataaattaa aaaaatcttt tttcaggact
     2101 ggagagtcag tggttaagac tgttctttca gaggtcctga gttcaaatcc cagcaaccac
     2161 atggtggttc acaaccatct gaaatgagat ctgatgccct cttctggtgt gtctgaagat
     2221 agcaacagtg tactcataca taataaataa attaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
