LOCUS       NM_001013907            2977 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus DnaJ heat shock protein family (Hsp40) member B12
            (Dnajb12), mRNA.
ACCESSION   NM_001013907 XM_215417
VERSION     NM_001013907.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2977)
  AUTHORS   Li K, Jiang Q, Bai X, Yang YF, Ruan MY and Cai SQ.
  TITLE     Tetrameric Assembly of K+ Channels Requires ER-Located Chaperone
            Proteins
  JOURNAL   Mol Cell 65 (1), 52-65 (2017)
   PUBMED   27916661
REFERENCE   2  (bases 1 to 2977)
  AUTHORS   Grove DE, Fan CY, Ren HY and Cyr DM.
  TITLE     The endoplasmic reticulum-associated Hsp40 DNAJB12 and Hsc70
            cooperate to facilitate RMA1 E3-dependent degradation of nascent
            CFTRDeltaF508
  JOURNAL   Mol Biol Cell 22 (3), 301-314 (2011)
   PUBMED   21148293
REFERENCE   3  (bases 1 to 2977)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 2977)
  AUTHORS   Yamamoto YH, Kimura T, Momohara S, Takeuchi M, Tani T, Kimata Y,
            Kadokura H and Kohno K.
  TITLE     A novel ER J-protein DNAJB12 accelerates ER-associated degradation
            of membrane proteins including CFTR
  JOURNAL   Cell Struct Funct 35 (2), 107-116 (2010)
   PUBMED   21150129
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JACYVU010000324.1.
            
            [WARNING] On Mar 27, 2024 this sequence was replaced by
            NM_001013907.3.
            
            On Nov 27, 2020 this sequence version replaced NM_001013907.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC090076.1, SRR8487227.12566.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-255               JACYVU010000324.1  23552094-23552348
            256-436             JACYVU010000324.1  23561542-23561722
            437-582             JACYVU010000324.1  23562281-23562426
            583-768             JACYVU010000324.1  23563894-23564079
            769-848             JACYVU010000324.1  23564163-23564242
            849-958             JACYVU010000324.1  23565552-23565661
            959-1131            JACYVU010000324.1  23566800-23566972
            1132-1229           JACYVU010000324.1  23567449-23567546
            1230-2977           JACYVU010000324.1  23568559-23570306
FEATURES             Location/Qualifiers
     source          1..2977
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q11"
     gene            1..2977
                     /gene="Dnajb12"
                     /note="DnaJ heat shock protein family (Hsp40) member B12"
                     /db_xref="GeneID:294513"
                     /db_xref="RGD:1359677"
     exon            1..255
                     /gene="Dnajb12"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..1259
                     /gene="Dnajb12"
                     /note="DnaJ (Hsp40) homolog, subfamily B, member 12"
                     /codon_start=1
                     /product="dnaJ homolog subfamily B member 12"
                     /protein_id="NP_001013929.1"
                     /db_xref="GeneID:294513"
                     /db_xref="RGD:1359677"
                     /translation="MESNKDEAERCISIALKAIQSNQPDRALRFLEKAQRLYPTPRVT
                     ALIESLNQKSQSAGDQSQPTDTTHTTTRKTSGTETPSANGEAGGGESTKGYTSEQVAA
                     VKRVKQCKDYYEILGVSRSASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYA
                     VLSNPEKRKQYDQFGDDKNQAARHGHSHGDFHRGFEADISPEDLFNMFFGGGFPSSNV
                     HVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLS
                     PRPSVGHIHKRVTDHLNVAYYVADTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEK
                     QQKEGLLYRARYFGDTDMYHRAQKMSTPSCSRLSETMKSLENFW"
     exon            256..436
                     /gene="Dnajb12"
                     /inference="alignment:Splign:2.1.0"
     exon            437..582
                     /gene="Dnajb12"
                     /inference="alignment:Splign:2.1.0"
     exon            583..768
                     /gene="Dnajb12"
                     /inference="alignment:Splign:2.1.0"
     exon            769..848
                     /gene="Dnajb12"
                     /inference="alignment:Splign:2.1.0"
     exon            849..958
                     /gene="Dnajb12"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1131
                     /gene="Dnajb12"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1229
                     /gene="Dnajb12"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..2977
                     /gene="Dnajb12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaggagggg cggagggtta tgtcatcctt ccgcgccggc ctgccccgcg acgcgccggc
       61 ggctggcgca gcccttcgct cgcccggcct ccccctccct ggttccgtgc tcgggttccg
      121 ccatggaatc caacaaggat gaagccgagc gctgtatcag catcgccctc aaggccatcc
      181 aaagcaacca gcccgaccgg gcgctgcgct tcctggagaa ggcgcagcgg ctgtacccga
      241 cgccaagagt caccgctctg atcgagtccc tcaaccaaaa atcacagtcc gccggtgatc
      301 aatctcaacc cacagacaca acccatacca ccaccaggaa gacaagcggg accgaaaccc
      361 cctcagccaa cggtgaggca ggaggaggag agagcaccaa gggctatact tcagagcagg
      421 tggcagctgt gaaaagggtc aagcagtgta aagattacta tgagatcctt ggggtaagca
      481 gaagcgcctc agacgaggac ctgaagaagg cctaccgcaa actggccctc aaattccatc
      541 cagacaagaa ccacgcgcct ggggccaccg aagctttcaa agccattggc acagcatatg
      601 ccgtcctcag caacccggag aaaaggaaac agtacgacca gtttggtgat gacaagaacc
      661 aggctgcccg gcacggccat agccacgggg acttccaccg aggctttgaa gccgacatct
      721 ccccagaaga cctctttaac atgttctttg gtggtggctt tccttccagt aacgtccatg
      781 tctacagcaa tggccgaatg cgatacacct accagcagag acaggaccgc agagacaacc
      841 agggtgatgg cgggctagga gtattcgtcc agctgatgcc catcctcatc ctcatcctcg
      901 tgtcggcgct cagccagctc atggtgtcca gtccacccta cagcctgagc cccagaccgt
      961 cagtgggcca tatccacaag cgagtcactg accacctgaa cgtcgcgtac tacgtggcag
     1021 acaccttctc tgaagagtac acaggctcta gcctcaaaac agttgaacgg aatgtggaag
     1081 acgattatat cgccaacctc cgaaacaact gctggaagga aaagcaacag aaggaaggct
     1141 tgctgtaccg agcccgatac tttggtgaca cagacatgta ccacagagca cagaagatga
     1201 gcaccccgag ttgcagtcgg ctgtcagaga ctatgaaatc cctggagaat ttttggtgac
     1261 acacactgag ccagccaagg tgatggacta tatatttaag taaagacatg cacagaaaaa
     1321 attaaaatgg actggaggcc gaacaccgca caaccgtcct ctctcagccc gtgaatgcgg
     1381 aaagctctta ggacggacag aaagcctgcc tggggctgct tcctcctctc ccagggctgg
     1441 caagaagctc tgcatcgccg gctcctagga taccgaaacc atggcaacga aagtagaatg
     1501 taaaacttgc agcaaatgtc tgtggggaag gactggggga ggggatgccc cactgtctct
     1561 cctccccctc cctggagctg ccaccagtca ctcccaggag aaaccaggca gaggcatggg
     1621 ccaaggaaca gaggagaaaa ttccagagaa cataacttag aaatgcgtac gtatgtatat
     1681 atatctattt atatgtaaat agacatatat aaagatatat atatatatat aaagtctttt
     1741 aaaactatgc agggattgga ttaagatgtt cagctgactt gctccatact ttagaaaacc
     1801 gggcctgttt gggaaggcgg cctggctttc aaaagcttga cagtaactgt agccgacagc
     1861 atagggaaag tcagatcaga cactgttagt gttgccctta gccccagcct gactgatggc
     1921 agcagtaatc atggtggtac aaatccatag aaaactccca aaggtctcca ggcttatggc
     1981 taaggtgggg gagcaagctg ggggcaggaa cggtgcctgc ccctggagat agctgctcag
     2041 tattgggcca tagcagagat ctcagacaag gcccgctggg aagaggcctg ctcctcacgc
     2101 tgcctcctcc ttggccagcc tcaggtgggc tctctgccct aatgcccagg agccctgcag
     2161 ccactcccct gcccatacct cttccccacc caagtcccca ggtgggtttg ccttacaggt
     2221 gccacagggc acagcttcac cattgccaac aggttttctc taagttgtgc accaaggact
     2281 ccagaaggct cttcctccaa aagctgaacc aggacctgag tgcagcccag cttgtggaga
     2341 accagggctg caagtgcctg tcttctccac agtgggccca ctgggttcca ctcgttggat
     2401 ggaggatcca ccacgaccag aatggcttcc cccttcagat gaggacggtt taccctcctc
     2461 ccacgtctat aatgggcctt tggggactgc tgtcccctag ttttcctatg gccgtgggtg
     2521 tgctcttgca cctgctgact tccaaagcct tacttcccca agctgccagc ccagaggtcg
     2581 gaactgtccc cccagggtct ctctctctct ctctcttttt ttttttaata caacccccta
     2641 acagataggg tgctgggaaa ggaagcttgg ttaggaattg tcaaatctgt tggttttttt
     2701 tttttttttt ttttaaacaa agtcccaccc tgcaatgaag tggccaccct ggcctagaga
     2761 gataataact ggatgcaggc cagagtaccc cacccacagt ggcctggtgc tctgcctccc
     2821 accaccccaa ctgtctggtc ttggtagctg tccctagagg ggctgagcca tgtgcaataa
     2881 gaacacagat cctaaaggat ccctgagaag ctgtatttct tgaattagaa ctctgatatt
     2941 gtacatctat aaatatatgt ttattatgtg attggca
//
