LOCUS       NM_001395149            2191 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus DnaJ heat shock protein family (Hsp40) member B1
            (Dnajb1), mRNA.
ACCESSION   NM_001395149 XM_006255282
VERSION     NM_001395149.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2191)
  AUTHORS   Krzemien-Ojak,L., Goral,A., Joachimiak,E., Filipek,A. and
            Fabczak,H.
  TITLE     Interaction of a Novel Chaperone PhLP2A With the Heat Shock Protein
            Hsp90
  JOURNAL   J Cell Biochem 118 (2), 420-429 (2017)
   PUBMED   27496612
REFERENCE   2  (bases 1 to 2191)
  AUTHORS   Xilouri,M. and Stefanis,L.
  TITLE     Chaperone mediated autophagy to the rescue: A new-fangled target
            for the treatment of neurodegenerative diseases
  JOURNAL   Mol Cell Neurosci 66 (Pt A), 29-36 (2015)
   PUBMED   25724482
  REMARK    Review article
REFERENCE   3  (bases 1 to 2191)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2191)
  AUTHORS   Rauch,J.N. and Gestwicki,J.E.
  TITLE     Binding of human nucleotide exchange factors to heat shock protein
            70 (Hsp70) generates functionally distinct complexes in vitro
  JOURNAL   J Biol Chem 289 (3), 1402-1414 (2014)
   PUBMED   24318877
REFERENCE   5  (bases 1 to 2191)
  AUTHORS   Jakobsson,M.E., Moen,A., Bousset,L., Egge-Jacobsen,W.,
            Kernstock,S., Melki,R. and Falnes,P.O.
  TITLE     Identification and characterization of a novel human
            methyltransferase modulating Hsp70 protein function through lysine
            methylation
  JOURNAL   J Biol Chem 288 (39), 27752-27763 (2013)
   PUBMED   23921388
REFERENCE   6  (bases 1 to 2191)
  AUTHORS   Doiguchi,M., Kaneko,T., Urasoko,A., Nishitani,H. and Iida,H.
  TITLE     Identification of a heat-shock protein Hsp40, DjB1, as an acrosome-
            and a tail-associated component in rodent spermatozoa
  JOURNAL   Mol Reprod Dev 74 (2), 223-232 (2007)
   PUBMED   16955402
REFERENCE   7  (bases 1 to 2191)
  AUTHORS   Lee,K.J., Terada,K., Oyadomari,S., Inomata,Y., Mori,M. and Gotoh,T.
  TITLE     Induction of molecular chaperones in carbon tetrachloride-treated
            rat liver: implications in protection against liver damage
  JOURNAL   Cell Stress Chaperones 9 (1), 58-68 (2004)
   PUBMED   15270078
REFERENCE   8  (bases 1 to 2191)
  AUTHORS   Yamagishi,N., Ishihara,K., Saito,Y. and Hatayama,T.
  TITLE     Hsp105 but not Hsp70 family proteins suppress the aggregation of
            heat-denatured protein in the presence of ADP
  JOURNAL   FEBS Lett 555 (2), 390-396 (2003)
   PUBMED   14644449
REFERENCE   9  (bases 1 to 2191)
  AUTHORS   Suzuki,T., Usuda,N., Murata,S., Nakazawa,A., Ohtsuka,K. and
            Takagi,H.
  TITLE     Presence of molecular chaperones, heat shock cognate (Hsc) 70 and
            heat shock proteins (Hsp) 40, in the postsynaptic structures of rat
            brain
  JOURNAL   Brain Res 816 (1), 99-110 (1999)
   PUBMED   9878698
REFERENCE   10 (bases 1 to 2191)
  AUTHORS   Shi,Y., Mosser,D.D. and Morimoto,R.I.
  TITLE     Molecular chaperones as HSF1-specific transcriptional repressors
  JOURNAL   Genes Dev 12 (5), 654-666 (1998)
   PUBMED   9499401
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Jun 4, 2021 this sequence version replaced XM_006255282.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC159430.1, SRR22582424.418701.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676787, SAMN16676810
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-311               JAXUCZ010000019.1  41430831-41431141   c
            312-892             JAXUCZ010000019.1  41428975-41429555   c
            893-2191            JAXUCZ010000019.1  41427453-41428751   c
FEATURES             Location/Qualifiers
     source          1..2191
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q11"
     gene            1..2191
                     /gene="Dnajb1"
                     /note="DnaJ heat shock protein family (Hsp40) member B1"
                     /db_xref="GeneID:361384"
                     /db_xref="RGD:1304725"
     exon            1..311
                     /gene="Dnajb1"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..1123
                     /gene="Dnajb1"
                     /note="DnaJ (Hsp40) homolog, subfamily B, member 1"
                     /codon_start=1
                     /product="dnaJ homolog subfamily B member 1"
                     /protein_id="NP_001382078.1"
                     /db_xref="GeneID:361384"
                     /db_xref="RGD:1304725"
                     /translation="MGKDYYQTLGLARGASDDEIKRAYRRQALRYHPDKNKEPGAEEK
                     FKEIAEAYDVLSDPRKREIFDRYGEEGLKGGGPSGGSSGGANGTSFSYTFHGDPHAMF
                     AEFFGGRNPFDTFFGQRNGEEGMDIDDPFSSFPMGMGGFTNMNFGRSRPTQEPTRKKQ
                     DPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKRGWKEGTKI
                     TFPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTL
                     DGRTIPVVFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPDRIPISSRTIL
                     EQVLPI"
     exon            312..892
                     /gene="Dnajb1"
                     /inference="alignment:Splign:2.1.0"
     exon            893..2191
                     /gene="Dnajb1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agggctggcg ggatctggaa gcttccgccg gacgggtata tagagtccgg gacggggcag
       61 cagcggagcc ggaggcggcg acagctgggc ggcggtggcc atgggcaagg actactacca
      121 gacgctgggc ctggcccgcg gcgcgtccga cgacgagatc aagcgggcct accgccgcca
      181 ggcgctgcgc taccacccgg acaagaacaa ggagcccggc gccgaggaga agttcaagga
      241 gatcgccgag gcctacgacg tgctcagcga cccgcgcaag cgcgagattt tcgaccgcta
      301 tggagaggaa ggcctgaagg gtggtggccc cagtggcggg agcagtggtg gtgctaatgg
      361 tacctctttc agctacacat tccatggaga ccctcatgct atgtttgctg agttcttcgg
      421 tggcaggaat ccctttgata ccttttttgg gcagcgcaac ggggaagaag gcatggacat
      481 cgatgacccg ttctctagct ttccgatggg tatgggcggc ttcaccaata tgaactttgg
      541 acgttcccgc cctactcaag agcccacccg gaagaagcaa gatcccccag tcacccacga
      601 ccttcgggtc tcccttgaag agatctacag cggctgtacc aagaagatga aaatctccca
      661 caagcggctg aaccctgatg gaaagagcat tcgaaatgaa gataagatcc tgaccatcga
      721 agtgaagagg ggctggaaag aagggaccaa aatcaccttt cccaaggaag gggaccagac
      781 ctcgaacaac attccagctg acatcgtctt tgttttaaag gacaagccac acaatatctt
      841 caagagagat ggttctgatg tcatttatcc agccaggatt agccttcggg aggctctctg
      901 tggttgcact gtgaatgttc ctactctgga cggcaggacc attcctgttg tattcaaaga
      961 tgtcatcagg cctggcatgc ggaggaaagt tcctggagaa ggcctccccc tccccaaaac
     1021 acctgagaaa cgtggagacc ttgttatcga atttgaagtc atcttccctg ataggatccc
     1081 catctcatcc agaaccatcc tggagcaggt tcttcccata tagctgcctg cattcctcaa
     1141 ggactgagcc agggaccttt ccagagctgc agatttccag accgttccac tggttgcata
     1201 ctgcgggagg gcccagggag ggcttttgct ctgccgaatg ttttccacag aatatattac
     1261 aatctttcaa agtcgcgcac tagactacag tggtttttcg agcgataggc aggcggtggg
     1321 aacagcagcc ctcctggaat ggacccaccc tttgcacccc agctcctgcc cgagggtgtg
     1381 aggcaggcct gcaactggac tcttcccctc tgctgtcctt aggttctggc tgtcacgtga
     1441 cagtggccca ccatctcggt tgccagaccc tgtgcactaa tcagtctcca ctgtgtgaga
     1501 ggttcttgtt ttattctgta tttgtcccct gccttgtcct cctccccaga agaatcctgt
     1561 cttgtcttgg ccatctcaaa ttgagaccaa ttctttagaa ctgccaggcc agcatcacaa
     1621 gcaatacctg gttgcaggac cacagggcca gcctccttcc aggttctggg gcctggacag
     1681 ccaggagatc ccctggacct ctggctctct tgaaatcaga tggctgcctt acagtcacag
     1741 tacttgctgg tccagaggta gcccttggcc acacctggca cttctcagag gtgcaggtga
     1801 cttttttgtg tgtgtgtatg tgtgtgtgta atggactcaa ctttctcaaa aggatacagt
     1861 ccttttgaat tttgcacagc cctagatata atcccttttg ataaaagggc ctttgcttct
     1921 gatgaaagga gcaccgtgga acgtatgtaa atatgttttt ataattccat gcaaagctgg
     1981 tgtgcacttg gatgaaagca gtccctgtca actactgcct gtccagggct gtgatgagtc
     2041 agacctgggg agggaatgga tctgttcttt ggagctagcc tggtgctctg accattcgac
     2101 tcattgtaag ttgccactac caacacaaga ccaaagtgtg tgacttgtca ttatgcagtg
     2161 tgacagcatt aaagactgat gctaaacctc a
//
