LOCUS       NM_032079               1908 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus DnaJ heat shock protein family (Hsp40) member A2
            (Dnaja2), mRNA.
ACCESSION   NM_032079
VERSION     NM_032079.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1908)
  AUTHORS   Rauch,J.N. and Gestwicki,J.E.
  TITLE     Binding of human nucleotide exchange factors to heat shock protein
            70 (Hsp70) generates functionally distinct complexes in vitro
  JOURNAL   J Biol Chem 289 (3), 1402-1414 (2014)
   PUBMED   24318877
REFERENCE   2  (bases 1 to 1908)
  AUTHORS   Hageman,J., van Waarde,M.A., Zylicz,A., Walerych,D. and
            Kampinga,H.H.
  TITLE     The diverse members of the mammalian HSP70 machine show distinct
            chaperone-like activities
  JOURNAL   Biochem J 435 (1), 127-142 (2011)
   PUBMED   21231916
REFERENCE   3  (bases 1 to 1908)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 1908)
  AUTHORS   Rosales-Hernandez,A., Beck,K.E., Zhao,X., Braun,A.P. and Braun,J.E.
  TITLE     RDJ2 (DNAJA2) chaperones neural G protein signaling pathways
  JOURNAL   Cell Stress Chaperones 14 (1), 71-82 (2009)
   PUBMED   18595009
  REMARK    GeneRIF: Rdj2 modulates G protein signaling and further suggest
            that chaperoning G proteins is an emerging theme of the J protein
            network.
REFERENCE   5  (bases 1 to 1908)
  AUTHORS   Smith,D.F. and Toft,D.O.
  TITLE     Minireview: the intersection of steroid receptors with molecular
            chaperones: observations and questions
  JOURNAL   Mol Endocrinol 22 (10), 2229-2240 (2008)
   PUBMED   18451092
  REMARK    Review article
REFERENCE   6  (bases 1 to 1908)
  AUTHORS   Prescott,J. and Coetzee,G.A.
  TITLE     Molecular chaperones throughout the life cycle of the androgen
            receptor
  JOURNAL   Cancer Lett 231 (1), 12-19 (2006)
   PUBMED   16356826
  REMARK    Review article
REFERENCE   7  (bases 1 to 1908)
  AUTHORS   Stelzl,U., Worm,U., Lalowski,M., Haenig,C., Brembeck,F.H.,
            Goehler,H., Stroedicke,M., Zenkner,M., Schoenherr,A., Koeppen,S.,
            Timm,J., Mintzlaff,S., Abraham,C., Bock,N., Kietzmann,S.,
            Goedde,A., Toksoz,E., Droege,A., Krobitsch,S., Korn,B.,
            Birchmeier,W., Lehrach,H. and Wanker,E.E.
  TITLE     A human protein-protein interaction network: a resource for
            annotating the proteome
  JOURNAL   Cell 122 (6), 957-968 (2005)
   PUBMED   16169070
REFERENCE   8  (bases 1 to 1908)
  AUTHORS   Lee,K.J., Terada,K., Oyadomari,S., Inomata,Y., Mori,M. and Gotoh,T.
  TITLE     Induction of molecular chaperones in carbon tetrachloride-treated
            rat liver: implications in protection against liver damage
  JOURNAL   Cell Stress Chaperones 9 (1), 58-68 (2004)
   PUBMED   15270078
REFERENCE   9  (bases 1 to 1908)
  AUTHORS   Terada,K. and Mori,M.
  TITLE     Human DnaJ homologs dj2 and dj3, and bag-1 are positive
            cochaperones of hsc70
  JOURNAL   J Biol Chem 275 (32), 24728-24734 (2000)
   PUBMED   10816573
REFERENCE   10 (bases 1 to 1908)
  AUTHORS   Andres,D.A., Shao,H., Crick,D.C. and Finlin,B.S.
  TITLE     Expression cloning of a novel farnesylated protein, RDJ2, encoding
            a DnaJ protein homologue
  JOURNAL   Arch Biochem Biophys 346 (1), 113-124 (1997)
   PUBMED   9328291
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087010.1.
            
            On Dec 26, 2004 this sequence version replaced NM_032079.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087010.1, U95727.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1908
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p11"
     gene            1..1908
                     /gene="Dnaja2"
                     /gene_synonym="Cpr3; Dj3; DjA2; Dnj3; Hirip4; Rdj2"
                     /note="DnaJ heat shock protein family (Hsp40) member A2"
                     /db_xref="GeneID:84026"
                     /db_xref="RGD:71001"
     exon            1..98
                     /gene="Dnaja2"
                     /gene_synonym="Cpr3; Dj3; DjA2; Dnj3; Hirip4; Rdj2"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..1259
                     /gene="Dnaja2"
                     /gene_synonym="Cpr3; Dj3; DjA2; Dnj3; Hirip4; Rdj2"
                     /note="DnaJ (Hsp40) homolog, subfamily A, member 2"
                     /codon_start=1
                     /product="dnaJ homolog subfamily A member 2"
                     /protein_id="NP_114468.2"
                     /db_xref="GeneID:84026"
                     /db_xref="RGD:71001"
                     /translation="MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPNAG
                     DKFKEISFAYEVLSNPEKRELYDRYGEQGLREGSGGGGGMDDIFSHIFGGGLFGFMGN
                     QSRSRNGRRRGEDMMHPLKVSLEDLYNGKTTKLQLSKNVLCSACSGQGGKSGAVQKCS
                     ACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILE
                     VHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLV
                     EALCGFQFTFKHLDARQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFD
                     VQFPENNWINPDKLSELEDLLPSRPEVPNVIGETEEVELQEFDSTRGSGGGQRREAYN
                     DSSDEESSSHHGPGVQCAHQ"
     exon            99..158
                     /gene="Dnaja2"
                     /gene_synonym="Cpr3; Dj3; DjA2; Dnj3; Hirip4; Rdj2"
                     /inference="alignment:Splign:2.1.0"
     exon            159..382
                     /gene="Dnaja2"
                     /gene_synonym="Cpr3; Dj3; DjA2; Dnj3; Hirip4; Rdj2"
                     /inference="alignment:Splign:2.1.0"
     exon            383..463
                     /gene="Dnaja2"
                     /gene_synonym="Cpr3; Dj3; DjA2; Dnj3; Hirip4; Rdj2"
                     /inference="alignment:Splign:2.1.0"
     exon            464..597
                     /gene="Dnaja2"
                     /gene_synonym="Cpr3; Dj3; DjA2; Dnj3; Hirip4; Rdj2"
                     /inference="alignment:Splign:2.1.0"
     exon            598..794
                     /gene="Dnaja2"
                     /gene_synonym="Cpr3; Dj3; DjA2; Dnj3; Hirip4; Rdj2"
                     /inference="alignment:Splign:2.1.0"
     exon            795..939
                     /gene="Dnaja2"
                     /gene_synonym="Cpr3; Dj3; DjA2; Dnj3; Hirip4; Rdj2"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1067
                     /gene="Dnaja2"
                     /gene_synonym="Cpr3; Dj3; DjA2; Dnj3; Hirip4; Rdj2"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1844
                     /gene="Dnaja2"
                     /gene_synonym="Cpr3; Dj3; DjA2; Dnj3; Hirip4; Rdj2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgctgccgg gcaggccgcc atggcgaacg tggccgacac gaagctgtac gacatcctgg
       61 gcgtccctcc cggcgccagc gagaacgagc tgaagaaggc ataccgaaag ttagccaaag
      121 aataccatcc tgataagaat ccaaatgctg gagataaatt taaagaaata agttttgcct
      181 atgaagtatt gtcaaatcca gagaagcggg agctatatga cagatatgga gaacaaggtc
      241 tacgggaagg cagcggcggg ggtggcggca tggatgatat tttctcacat atttttggtg
      301 gaggattgtt tggcttcatg ggcaatcaaa gtagaagtcg aaatggcaga agaagaggcg
      361 aggacatgat gcatccgctg aaagtgtctt tagaagacct gtacaatggc aagaccacca
      421 agctgcagct cagcaagaat gtgctctgta gcgcgtgcag tggccaaggt ggaaagtctg
      481 gagctgttca gaaatgcagt gcttgccggg gtcgaggtgt gcgcattatg ataagacagc
      541 tggctccagg gatggtacag cagatgcagt ctgtgtgctc tgactgtaat ggagaaggag
      601 aggtcatcaa tgaaaaagac cgctgtaaaa aatgtgaagg aaagaaggtg attaaagaag
      661 tcaagattct ggaagttcat gtagacaaag gcatgaaaca tggacagaga attacgttca
      721 ctggggaagc agaccaggct ccaggagtgg aacctggaga tattgttctt ttgctacagg
      781 aaaaagaaca tgaggtgttc cagagagatg ggaatgatct gcatatgaca tataagatag
      841 gacttgttga agctttgtgt ggatttcagt tcacatttaa acatcttgat gctcgtcaga
      901 ttgtagtgaa atacccccct ggcaaagtaa ttgaaccagg atgtgttcgt gttgttcgag
      961 gcgaaggaat gccacagtat cgtaatccct ttgaaaaggg tgatctttac ataaagtttg
     1021 atgtgcagtt tcctgaaaac aactggatca acccagacaa actttctgaa ttagaagacc
     1081 tcctgccatc tagaccagaa gttcctaatg taattgggga gacagaagaa gtagagcttc
     1141 aggaattcga tagcactcga ggctctggag gtggtcagag gcgtgaagcc tacaacgaca
     1201 gctctgatga ggaaagcagc agccatcatg gacctggagt gcagtgtgcc catcagtaaa
     1261 ctgcaggcaa ctgcacggtg gattttctcc acatttgccg gatttgccag ctgctggagt
     1321 acctgatgag tccagatgaa ctgatggaca tctgctgatc tatgtgtaac ttctaaactt
     1381 ggtatagtat ccacagagtg tataatttaa actaaccacg gagctttacg tcttcatttc
     1441 gactgttcta tagcagagta aagcacttga aataagactc cctttcacat gtgggttata
     1501 agtttcagtc ctggtatctg cttgattttt atcagttttg tgtagagttt atgtttccta
     1561 ttttaaactc agatccagca ttgtaaagtt tgtacaattc gtcctgaagc tgtgtgtttg
     1621 gctgcacctg cataagctgc tacaaataga ataaagaatt catagcctgt atctatcatt
     1681 agatgcatgg aaaactgggc tttgcacaca atgggtttga agctgactgg gaacaatgga
     1741 aaaaattaca ttagccatgg ttgtaaagtt ttttggcttt tttttaaaac cattttgtga
     1801 aaggtttctg aaacttgata ataaaaagca gttggtgtaa attaaaaaaa aaaaaaaaaa
     1861 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
