LOCUS       NM_001025659            1698 bp    mRNA    linear   ROD 17-JUL-2023
DEFINITION  Rattus norvegicus dynein axonemal assembly factor 11 (Dnaaf11),
            mRNA.
ACCESSION   NM_001025659 XM_235289
VERSION     NM_001025659.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1698)
  AUTHORS   Mali GR, Yeyati PL, Mizuno S, Dodd DO, Tennant PA, Keighren MA, Zur
            Lage P, Shoemark A, Garcia-Munoz A, Shimada A, Takeda H, Edlich F,
            Takahashi S, von Kreigsheim A, Jarman AP and Mill P.
  TITLE     ZMYND10 functions in a chaperone relay during axonemal dynein
            assembly
  JOURNAL   Elife 7, e34389 (2018)
   PUBMED   29916806
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1698)
  AUTHORS   Mahuzier A, Shihavuddin A, Fournier C, Lansade P, Faucourt M,
            Menezes N, Meunier A, Garfa-Traore M, Carlier MF, Voituriez R,
            Genovesio A, Spassky N and Delgehyr N.
  TITLE     Ependymal cilia beating induces an actin network to protect
            centrioles against shear stress
  JOURNAL   Nat Commun 9 (1), 2279 (2018)
   PUBMED   29891944
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1698)
  AUTHORS   Inaba Y, Shinohara K, Botilde Y, Nabeshima R, Takaoka K, Ajima R,
            Lamri L, Takeda H, Saga Y, Nakamura T and Hamada H.
  TITLE     Transport of the outer dynein arm complex to cilia requires a
            cytoplasmic protein Lrrc6
  JOURNAL   Genes Cells 21 (7), 728-739 (2016)
   PUBMED   27353389
REFERENCE   4  (bases 1 to 1698)
  AUTHORS   Kott E, Duquesnoy P, Copin B, Legendre M, Dastot-Le Moal F,
            Montantin G, Jeanson L, Tamalet A, Papon JF, Siffroi JP, Rives N,
            Mitchell V, de Blic J, Coste A, Clement A, Escalier D, Toure A,
            Escudier E and Amselem S.
  TITLE     Loss-of-function mutations in LRRC6, a gene essential for proper
            axonemal assembly of inner and outer dynein arms, cause primary
            ciliary dyskinesia
  JOURNAL   Am J Hum Genet 91 (5), 958-964 (2012)
   PUBMED   23122589
REFERENCE   5  (bases 1 to 1698)
  AUTHORS   Xue JC and Goldberg E.
  TITLE     Identification of a novel testis-specific leucine-rich protein in
            humans and mice
  JOURNAL   Biol Reprod 62 (5), 1278-1284 (2000)
   PUBMED   10775177
  REMARK    GeneRIF: Identification and characterization of the mouse and human
            Lrrc6 (LRTP) orthologs.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC097394.1.
            
            On Oct 25, 2007 this sequence version replaced NM_001025659.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760389
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-932               BC097394.1         1-932
            933-1698            BC097394.1         934-1699
FEATURES             Location/Qualifiers
     source          1..1698
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q33"
     gene            1..1698
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /note="dynein axonemal assembly factor 11"
                     /db_xref="GeneID:299920"
                     /db_xref="RGD:1559937"
     exon            1..80
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..1489
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /note="leucine-rich testis-specific protein; leucine rich
                     repeat containing 6 (testis)"
                     /codon_start=1
                     /product="dynein axonemal assembly factor 11"
                     /protein_id="NP_001020830.2"
                     /db_xref="GeneID:299920"
                     /db_xref="RGD:1559937"
                     /translation="MGRITEDLIRRNAEHNECVIFSLEELSLHQQEIERLEHIDKWCR
                     DLKILYLQNNLIAKIENVSKLKKLEYLNLALNNIERIENLEGCEWLTKLDLTVNFIGE
                     LSSIKTLTHNIHLRELFLVGNPCADFDGYREFVVVTLQQLKWLDGKEIERSERIQALQ
                     NYAAVEQQIREQEKAYCLRRAKEKEEAQRKLEEENESEDKKKSSPGFDGDCYTDIHAD
                     CPSAMENKDHLQVPETQEQQHSTKKSDEIEDDLAFWNKPSLFTPESRLETLRHMEKQR
                     KAQDKLSEKKKRVKPPRTLITEDGKVLNVNEAKLDFSLKDDEKHNQIILDLAVYRYMD
                     TSLIEVDVQPTYVRVMVKGKPFQLALSAEVQPDSSSAKRSQTTGHLLICMPKVGEMIT
                     GQQTPMSVKTASESSKEQTKPRRKQVERLEVDPSKHSCPDVSTIVQERKHKPKRMESQ
                     PQVEPSEAEPDFDDNPEVPPLI"
     exon            81..248
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
     exon            249..326
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
     exon            327..499
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
     exon            500..726
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
     exon            727..918
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
     exon            919..996
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1062
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1132
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1228
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..1311
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1673
                     /gene="Dnaaf11"
                     /gene_synonym="Lrrc6; Lrtp; Tslrp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgagggttg aggggaatcc cgccggtcgt ctccttgttt ccctgactag agatccagaa
       61 aagcagcgcc atgggccgaa tcacagaaga tcttattaga cggaatgctg agcacaacga
      121 atgtgtaatt ttttccctgg aggaactctc cttgcatcag caagaaatag aaagactaga
      181 acatattgac aaatggtgcc gtgatttaaa aattctctat cttcaaaata acctcattgc
      241 aaaaattgaa aatgttagca aactgaagaa acttgaatac ttgaacttag cattgaacaa
      301 cattgaaaga attgaaaact tggaaggatg tgagtggctg accaaacttg acttgactgt
      361 aaatttcatt ggagaactga gtagcattaa aaccctgaca cacaatattc atctgaggga
      421 gctattcctc gtgggtaacc catgtgctga ctttgacggc tacagggagt ttgtggtggt
      481 gaccttacaa cagttaaagt ggttggatgg caaagaaata gaacgttctg aaaggatcca
      541 agcactgcag aactacgcag cagttgaaca gcaaatcaga gagcaggaga aagcttactg
      601 ccttagacgt gccaaagaga aagaggaagc tcagaggaaa ctggaggaag aaaacgaaag
      661 tgaagacaaa aagaagagca gcccaggctt tgatggggat tgttacacag acatccacgc
      721 tgattgccca tctgccatgg agaacaaaga ccatcttcag gtaccagaaa cacaagaaca
      781 acaacatagc acaaagaaat cagatgaaat tgaagatgat ctggcattct ggaacaaacc
      841 gtctttgttc actcctgaat ctagattgga aactctcaga cacatggaaa agcaacgcaa
      901 agcccaagat aagttaagtg aaaagaaaaa aagagtgaaa ccaccccgga ctttgattac
      961 agaagatggg aaggtcctga atgtgaatga agccaaactt gatttctcct tgaaagatga
     1021 tgagaaacac aaccagatca tcctggacct ggctgtctat aggtacatgg acacctcttt
     1081 aattgaggtt gatgtgcagc caacctatgt tcgagtaatg gtcaaaggaa agccatttca
     1141 gcttgccctt tctgcagagg tccagcctga cagcagctct gctaaaaggt ctcagacaac
     1201 aggacatttg ctgatctgca tgcccaaggt aggagaaatg atcacaggtc aacaaacacc
     1261 catgtctgtg aagaccgcct cggagagcag caaggaacaa acaaagccca gaagaaagca
     1321 ggtagaaaga ttagaagttg atcccagcaa gcattcctgc cctgatgtgt ctactatagt
     1381 acaagagaga aaacacaaac ccaaaaggat ggaatctcaa ccacaagttg aacccagtga
     1441 ggcagagcca gactttgacg ataacccaga ggtgcctcca ctcatttgaa acatgaggat
     1501 ggattgttac tgactgcgag ccacagaccc atgttgcttt gtgttgacag tggaaatgtg
     1561 tcattcatgg ggtaaacata gttcgttccc attttatctg atgctataat gctcactttg
     1621 cataataata ctcttaagtg aatttacaat taaattgcgt tccttgaata tgcaaaaaaa
     1681 aaaaaaaaaa aaaaaaaa
//
