LOCUS       NM_001107951            2948 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus DMRT-like family A2 (Dmrta2), mRNA.
ACCESSION   NM_001107951 XM_001068179 XM_006238589 XM_233363
VERSION     NM_001107951.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2948)
  AUTHORS   Saulnier,A., Keruzore,M., De Clercq,S., Bar,I., Moers,V.,
            Magnani,D., Walcher,T., Filippis,C., Kricha,S., Parlier,D.,
            Viviani,L., Matson,C.K., Nakagawa,Y., Theil,T., Gotz,M.,
            Mallamaci,A., Marine,J.C., Zarkower,D. and Bellefroid,E.J.
  TITLE     The doublesex homolog Dmrt5 is required for the development of the
            caudomedial cerebral cortex in mammals
  JOURNAL   Cereb Cortex 23 (11), 2552-2567 (2013)
   PUBMED   22923088
REFERENCE   2  (bases 1 to 2948)
  AUTHORS   Rajan,S., Chu Pham Dang,H., Djambazian,H., Zuzan,H., Fedyshyn,Y.,
            Ketela,T., Moffat,J., Hudson,T.J. and Sladek,R.
  TITLE     Analysis of early C2C12 myogenesis identifies stably and
            differentially expressed transcriptional regulators whose
            knock-down inhibits myoblast differentiation
  JOURNAL   Physiol Genomics 44 (2), 183-197 (2012)
   PUBMED   22147266
REFERENCE   3  (bases 1 to 2948)
  AUTHORS   Konno,D., Iwashita,M., Satoh,Y., Momiyama,A., Abe,T., Kiyonari,H.
            and Matsuzaki,F.
  TITLE     The mammalian DM domain transcription factor Dmrta2 is required for
            early embryonic development of the cerebral cortex
  JOURNAL   PLoS One 7 (10), e46577 (2012)
   PUBMED   23056351
REFERENCE   4  (bases 1 to 2948)
  AUTHORS   Gennet,N., Gale,E., Nan,X., Farley,E., Takacs,K., Oberwallner,B.,
            Chambers,D. and Li,M.
  TITLE     Doublesex and mab-3-related transcription factor 5 promotes
            midbrain dopaminergic identity in pluripotent stem cells by
            enforcing a ventral-medial progenitor fate
  JOURNAL   Proc Natl Acad Sci U S A 108 (22), 9131-9136 (2011)
   PUBMED   21576465
REFERENCE   5  (bases 1 to 2948)
  AUTHORS   Murphy,M.W., Zarkower,D. and Bardwell,V.J.
  TITLE     Vertebrate DM domain proteins bind similar DNA sequences and can
            heterodimerize on DNA
  JOURNAL   BMC Mol Biol 8, 58 (2007)
   PUBMED   17605809
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On or before Dec 3, 2020 this sequence version replaced
            XM_006238589.1, NM_001107951.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR21887622.2190896.1,
                                           SRR21887622.2190903.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680422, SAMN06680423
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-283               JAXUCZ010000005.1  130034473-130034755
            284-847             JAXUCZ010000005.1  130036319-130036882
            848-2948            JAXUCZ010000005.1  130038122-130040222
FEATURES             Location/Qualifiers
     source          1..2948
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q35"
     gene            1..2948
                     /gene="Dmrta2"
                     /note="DMRT-like family A2"
                     /db_xref="GeneID:313471"
                     /db_xref="RGD:1308173"
     exon            1..283
                     /gene="Dmrta2"
                     /inference="alignment:Splign:2.1.0"
     exon            284..847
                     /gene="Dmrta2"
                     /inference="alignment:Splign:2.1.0"
     CDS             292..1902
                     /gene="Dmrta2"
                     /note="doublesex and mab-3 related transcription factor
                     like family A2"
                     /codon_start=1
                     /product="doublesex- and mab-3-related transcription
                     factor A2"
                     /protein_id="NP_001101421.2"
                     /db_xref="GeneID:313471"
                     /db_xref="RGD:1308173"
                     /translation="MELRSELPSVPGAATAAATATGPPVASVASVAAAAAAAASLPVS
                     VAGGLLRAPPLLLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIA
                     ERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVC
                     ATDGGGPGAGAPAGSAGGAGGAGGAEAKLQKFDLFPKTLLQAGRPDSPQPPPGKPLSP
                     DGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGASGGGEEDS
                     PGSSSPLGSESGSEADKEEAEAAPTPGLGGGPGPRQRTPLDILTRVFPGHRRGVLELV
                     LQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPLEKAAVSAAAAVEDAWPGRVEAAAAG
                     GAGLPAPLQTGPAAPPHHRPLLAGAMTPGALGSLSSRSAFSPLQPNASHFGADAGAYP
                     LGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRSA
                     AAAAAVHKEPGYGGGLYGPMVNGTPEKQ"
     exon            848..2948
                     /gene="Dmrta2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggactacccg gcccggggcg agcgcagcgt ccggagcgca ccgaggggac gcgggttgca
       61 accagagggc ccccgaccag acccccggcc ccgaggccct ccgtggtgtt ggactgctgt
      121 gttcccagag gggtccggaa gttcggacat ggtggctgaa ggagggtgac gtggtcagag
      181 aaggggccca gggcaaaggg acgaggctga gaaagccgct gagcgagcgg ggctgggcaa
      241 cgcgtgctgc gccatcggag gaggagccag gagctggaga caggtccagc catggagctg
      301 cgctcggagc tgcccagcgt gcccggcgcg gcgacagcag cagcgacagc gacgggacca
      361 cccgtggcat ccgtggcgtc cgtggctgcg gcggcagctg ccgcagcatc gctaccagtg
      421 agcgtggccg gaggcttgct gcgggcgccg ccgctgctgt tgagggcagc ggagaagtac
      481 ccgcggaccc ccaagtgcgc gcgctgccgc aaccacggag tggtgtccgc gctcaagggc
      541 cacaagcgct actgccgctg gaaggactgc ctgtgcgcca agtgcacgct catcgccgag
      601 cgccagcgcg tcatggcggc ccaggtggcg ttgcgcaggc agcaggcgca ggaggaaaac
      661 gaggcacgcg agttgcaact gctgtacggc actgccgagg gcctggcgct ggccgccgcc
      721 aacggcatca tcccaccgcg gccagcttac gaagtctttg gctcggtttg cgccaccgac
      781 ggcggggggc cgggagctgg agcgcccgcg gggagtgcag ggggcgctgg gggcgcaggg
      841 ggcgcagagg ccaagttgca gaagtttgat ctgtttccca agacgctact tcaggccggc
      901 cgcccagaca gtccgcagcc gccgccaggg aagcccttgt cgcccgacgg cgcggactca
      961 ggtcccggga cctcgtcccc ggaggtgcgg cccggttcag gctcggagaa cggagatggc
     1021 gagtcctttt ccgggtcgcc tctggcccgt gcctccaagg aggcgggtgg cagctgtcct
     1081 gggagcgcgg gcgccagcgg tggcggcgag gaggacagcc ccggctcctc cagccccctg
     1141 ggttcggaat cgggctcgga agctgacaaa gaagaagccg aggccgcacc gactccaggg
     1201 ctgggcggcg ggccggggcc gcggcagcgg acgccgctgg acatcttgac gcgtgtcttc
     1261 ccgggccacc ggagaggcgt cctggagctg gtgcttcagg gctgtggcgg cgacgtggtg
     1321 caggccattg agcaggtgct caaccaccac cgcggaggcc tggcggccgg cctgggcccc
     1381 gccgcgccgc tggagaaagc cgcggtgagc gcggccgcgg cggtggagga cgcgtggccc
     1441 ggacgcgtgg aggctgcagc cgccggggga gccgggctgc ccgctccgct gcagaccggg
     1501 cccgcagcgc ccccgcacca cagacccttg ctggccgggg ccatgacgcc cggcgcgctg
     1561 ggctcgctca gcagccggtc cgccttctcg cctctgcagc ccaacgccag ccacttcggc
     1621 gccgacgcgg gcgcctaccc tctgggcgcg ccgctcggcc tgagcccgct gcgcctggcc
     1681 tactccgcag cagcggccca cagccgcggt ctggccttca tggcgcccta ctccacggcc
     1741 ggcctggtgc ccacgctcgg cttccggccg cccatggact acgccttcag cgacctcatg
     1801 cgcgaccgct cggccgccgc cgccgccgcg gtgcacaagg agcccggtta cgggggcggg
     1861 ctgtacgggc ccatggtcaa cggcacccct gagaagcagt agggtacggg gaccgacagc
     1921 ccgaacaccc cgaaacatcg acccagcctg cttccccagt cgcggacccc tcctcgctct
     1981 gccctgcgcc ctccgctcac aattggcttt aggggcttct ttgggagggt gggtgagtgg
     2041 gtgggagcat ctcggctgac cctgcaggtg tcctcagagg agccttgtgg tctgggtgct
     2101 cttcccacct ccggccacct tcccctaggc ctgctcgccc tgttgtcaag aggctgggga
     2161 tccctaagaa ccccgagggc gactgcggcc tcgctcgcct ctgctgctcc ctctgctccg
     2221 ctcgcctttc cagccctcgc tcaggtggat ggcaggatgg atcagcccct tgtgtgtcct
     2281 ccaataccca ttcccctttc gtttaaaaaa aaatccgctc taacaaatat aaatttagga
     2341 tgtatacatc tcttggcact gagtcgagtc tttgggacac atatatatcg atatcaattg
     2401 taaaaaaaaa aaaaaaagga aacgttctaa ggtgcacttt cctcgttgcg gtatttgtcg
     2461 ctctctttgt tgcttatgcg gataagcatg ggtttccttg gtgcagtgtg agtttttata
     2521 tatgtataaa tctatatata atctatacat atatatatac aagccagtgt ataatgttat
     2581 aaaatggaat tctaagttat taattgtaat ctgtaggtga cctcggtatt aacgtgaaaa
     2641 acactcaaaa atcaaagcaa aaaaaaaaag gacaaaatgg aaaaaattag actattcgcg
     2701 cattgtacgt atcgggtttc atagctgaaa tctactgttc gctggggagg aaccctgccg
     2761 atccctggcc cccggcctgc ggctgttctc caaagctgtc caggctgcgc tggagcacga
     2821 ataaagcgtc gggtgagcga gccagaagct ccgggactcg ccagcaagcg acgctgcgca
     2881 gaactgctca ctttgtgctt tcctttgcat aggtatgagc tagaaataaa tgttattttc
     2941 taaataaa
//
