LOCUS       NM_001107597            2331 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus doublesex and mab-3 related transcription factor
            2 (Dmrt2), mRNA.
ACCESSION   NM_001107597 XM_001080139 XM_219927
VERSION     NM_001107597.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2331)
  AUTHORS   Lourenco R, Lopes SS and Saude L.
  TITLE     Left-right function of dmrt2 genes is not conserved between
            zebrafish and mouse
  JOURNAL   PLoS One 5 (12), e14438 (2010)
   PUBMED   21203428
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2331)
  AUTHORS   Seo KW.
  TITLE     Dmrt2 and Pax3 double-knockout mice show severe defects in
            embryonic myogenesis
  JOURNAL   Comp Med 57 (5), 460-468 (2007)
   PUBMED   17974128
REFERENCE   3  (bases 1 to 2331)
  AUTHORS   Murphy MW, Zarkower D and Bardwell VJ.
  TITLE     Vertebrate DM domain proteins bind similar DNA sequences and can
            heterodimerize on DNA
  JOURNAL   BMC Mol Biol 8, 58 (2007)
   PUBMED   17605809
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2331)
  AUTHORS   Seo KW, Wang Y, Kokubo H, Kettlewell JR, Zarkower DA and Johnson
            RL.
  TITLE     Targeted disruption of the DM domain containing transcription
            factor Dmrt2 reveals an essential role in somite patterning
  JOURNAL   Dev Biol 290 (1), 200-210 (2006)
   PUBMED   16387292
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_219927.4, XM_001080139.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760384,
                              SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2331
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q51"
     gene            1..2331
                     /gene="Dmrt2"
                     /note="doublesex and mab-3 related transcription factor 2"
                     /db_xref="GeneID:309430"
                     /db_xref="RGD:1309047"
     exon            1..342
                     /gene="Dmrt2"
                     /inference="alignment:Splign:2.1.0"
     exon            343..900
                     /gene="Dmrt2"
                     /inference="alignment:Splign:2.1.0"
     CDS             382..2064
                     /gene="Dmrt2"
                     /codon_start=1
                     /product="doublesex- and mab-3-related transcription
                     factor 2"
                     /protein_id="NP_001101067.1"
                     /db_xref="GeneID:309430"
                     /db_xref="RGD:1309047"
                     /translation="MEGQAVPGVGDWEIDVESLELEEDGCGTPLRATPQEPSPSTADG
                     EEDEDEEEEDEDAEDEGEGEDSSASPEVPGRPEQPGGLAPRPPPAAQALPAAAVVPER
                     GVTAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVM
                     AAQVALRRQQATEDKKGLSGKQNNFDRKAVYQRQVRAPSLLAKSILEGYRPMTAAETY
                     LGGTLPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPG
                     PEYSSYKGAFSPSAGELPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQY
                     PLSSRFLVWPKCGPISDTLLYQQYLLNATTSVQALKPGAGWDLKGTRVQDGLSAEHDG
                     MPPKPEGSLVLPQLSEVPTSRTDLQAHQAVPERSAFSPPSRNFSPIVDMDCLAAQGHV
                     LTKISKENTRYPLPLKRNPFHSVFQPTLNDKSGPELKAPFVKEAFEETPKKHRECLVK
                     ENPKYTFTIDRCAKDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAVTPVSQ"
     exon            901..1003
                     /gene="Dmrt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1004..2331
                     /gene="Dmrt2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggactgcaga gagtgactcc gcgctgaagg caagcagagt gcgcctgagg cggagttctg
       61 ggtcgccggc cgacctttcc agtttgggcc agaagtggaa agcgaagcga agcgacccag
      121 gctgcagagg cccggacaga actttgcaga atttggaatg tacggggtga ggttgctgag
      181 gacttgattc gcctctggcc tctgtctccc atcaccatcc agtgggctcc cgcctcctac
      241 tctcaggccc aattctgttt gctcccgctg cttgcagctc gggggacaga ttccgaagct
      301 ggctgtcttt taactgggtt gctagcctga gcctggttct tgcgcgcggg caaccgaacc
      361 gaactacagc ctagtgtcac gatggaaggg caggcagtcc ccggagttgg ggactgggag
      421 atcgacgtgg agagcctaga gctggaggag gatggctgtg ggacaccgtt gcgggccacg
      481 ccacaggaac ccagtccgtc gacggccgat ggagaggaag atgaggacga agaagaggaa
      541 gatgaagatg cagaggatga gggtgaaggc gaggactcca gcgcgtcccc ggaggtacca
      601 ggtcggccag agcagcccgg gggactggca cccaggccac cgcccgctgc tcaggcgctg
      661 ccagccgccg ccgtagtccc cgagcgcggt gtcaccgccg gtggcggcgc agagccccgt
      721 aaactgagcc gcacgcccaa gtgcgcacgc tgccgtaacc acggcgtggt gtcctgtctc
      781 aagggccaca agcgattctg tcgctggcgg gactgccagt gcgccaactg cctgcttgtg
      841 gtagagcgcc agcgagtcat ggccgcccag gtggcgctcc ggaggcagca ggccacagag
      901 gacaagaagg ggctttctgg gaaacagaat aatttcgatc ggaaagcagt gtaccagagg
      961 caagtcaggg cgccaagctt gctggccaaa agcattttag aagggtaccg cccaatgacg
     1021 gcggccgaga cttacctagg agggaccctt cccctacccc cgcctgtcag tgacaggatg
     1081 aggaagagaa gagcatttgc tgacaaggag ttggagaaca ttatgctgga gagagaatat
     1141 aaagagaggg agatgttaga aacatctcaa gccgctgcct tgtttctgcc caatcgcatg
     1201 gtgcccgggc ctgagtacag ttcctacaaa ggtgccttca gccccagcgc aggcgagctg
     1261 ccgagcaagg acttctgtaa ctttttacct acctgtctcg atctcaccat gcagtattca
     1321 gggtctggga atatggaact gatttcttcc aatgtcagcg tggccacaac ttacagacaa
     1381 tatcccctgt cctcgcgatt tttagtctgg cccaagtgcg gtcccattag cgacaccctc
     1441 ctctaccagc aatacctgtt aaatgctacc acttctgtcc aagccctgaa gcctggggcc
     1501 ggctgggact tgaaaggaac ccgagttcag gatgggctta gtgcagagca tgacgggatg
     1561 ccacccaaac cggaaggctc tctagtgctg cctcaactat cagaggtccc gacctcaaga
     1621 actgaccttc aggctcacca ggctgtccca gagaggtctg ccttctcccc accgagccgg
     1681 aatttctccc ccattgttga tatggactgt ctggcagctc aagggcacgt cttaaccaag
     1741 atcagcaaag aaaacactag gtatcctctg ccacttaaac gtaatccatt ccactcagta
     1801 ttccagccga cgctcaacga caaatcaggc cctgaattga aagcaccgtt tgtcaaagaa
     1861 gcctttgaag agaccccgaa gaaacacagg gagtgtttgg tcaaggagaa cccgaagtac
     1921 acatttacaa tagacagatg cgcaaaagac ctcttcgtag ccaaacaagt tggaacgaaa
     1981 ctctcggtga acgagcctct gtcgttttcc gtggaatcta ttcttaagag gccctcatct
     2041 gctgtcactc ccgtctctca gtgaagggct gcttgcaagg gaagctggat ttttctccag
     2101 tctcctggag atgccttttt tctttttaaa gttaagatgt gtgtatagag aaatttttaa
     2161 tgtaaatgac caattcttaa gatcctacat gtttcctccg catgtatctt ttcgtatcac
     2221 gcgagtatat ttaaagacgg aaactactta ctgtgcaaat tgtaagggct tatgctttct
     2281 ttagccagca ttctgaaaag caataaaaat aacaccgtct tctaaagacc c
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