LOCUS       NM_001173357            2016 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus dermokine (Dmkn), mRNA.
ACCESSION   NM_001173357 XM_001079275 XM_341835
VERSION     NM_001173357.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2016)
  AUTHORS   Leclerc EA, Huchenq A, Kezic S, Serre G and Jonca N.
  TITLE     Mice deficient for the epidermal dermokine beta and gamma isoforms
            display transient cornification defects
  JOURNAL   J Cell Sci 127 (Pt 13), 2862-2872 (2014)
   PUBMED   24794495
REFERENCE   2  (bases 1 to 2016)
  AUTHORS   Moffatt P, Salois P, St-Amant N, Gaumond MH and Lanctot C.
  TITLE     Identification of a conserved cluster of skin-specific genes
            encoding secreted proteins
  JOURNAL   Gene 334, 123-131 (2004)
   PUBMED   15256262
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166816.1.
            
            On or before May 13, 2010 this sequence version replaced
            XM_341835.4, XM_001079275.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166816.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132301, SAMN11044071
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2016
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..2016
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /note="dermokine"
                     /db_xref="GeneID:361548"
                     /db_xref="RGD:1561521"
     exon            1..491
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..1667
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /codon_start=1
                     /product="dermokine precursor"
                     /protein_id="NP_001166828.1"
                     /db_xref="GeneID:361548"
                     /db_xref="RGD:1561521"
                     /translation="MKPQGSLACLLLALCLGSGVANPLHSGGEGTGANAAPGMGGTIS
                     HGIGESVGQGAKEAASSGIQDALGQGHGEGGYALMGGRGDVFDHQLGEAARSLENAGN
                     EIGRRAEDVIRRGVDAAHNSGSWGTSGGHGVYGSQGGFGSQGNPGVEGTPWASGGNYG
                     TNSLGGSVGQGGSGRPLNYETNAQGAVAQPGYGAVRGNNQNSGCTNPPPSDSHESFSD
                     SGGSSNGGSHGGQGNQGSNGQGNSGGNSGQGSSGSSGNSGNNEGSGGHSGNSGGNSGS
                     GSRDLETSNFDDGYSVSRGTSSSSGSRGGSGGGGNRPECNNPGNDVRMAGGSGSQESK
                     ESSHLLGGSHDYQGHGSGHGSNGGNVQRDAVSGLNTMNSDASSLPFNLDNFWENFKSK
                     MGFINWDAINKGRGPAPSTRALLYFRRLWENFKRNTPFFNWKQIEGSDLSSLQKRAGG
                     ADQFSQPEAARQDLSAESAKNYYNNAQVNPTYNWQYYTKTTPKAGVTPSSSASRAQPG
                     LLKWLKFW"
     exon            492..668
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            669..725
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            726..776
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            777..953
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            954..998
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1058
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1109
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1157
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1229
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1277
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1325
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1382
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1383..1427
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1475
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1526
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1527..1595
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1596..1619
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1620..1667
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
     exon            1668..1985
                     /gene="Dmkn"
                     /gene_synonym="RGD1561521"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggaaggga gaataggaag caaggaggga aaggcaggtc tcagcccaga ggaagagaag
       61 ggaacaagtg gactgggctg cagagattct caggggagag agggagctgg gcagagatga
      121 agccacaagg gtctctggcc tgtctcctgc tggccctatg tctgggcagc ggggtagcta
      181 atccgctgca cagcggaggg gagggcacag gggcaaatgc tgcccccgga atgggaggta
      241 ccattagcca tggaattgga gagtctgtgg gccaaggggc taaagaagca gccagctctg
      301 gaatccagga tgccctgggt caggggcacg gcgaaggtgg ctacgcactg atggggggca
      361 gaggcgatgt tttcgaccac cagcttgggg aggcagctcg atctctggag aacgctggga
      421 atgagattgg cagacgggct gaggatgtta ttcgcagagg ggtagacgct gcccacaact
      481 ctgggtcctg ggggacatct ggaggtcatg gcgtgtatgg ctctcaaggt ggttttggaa
      541 gccagggcaa tcctggtgtt gaagggacac cctgggcctc aggaggcaac tatggaacta
      601 actctctggg tggctctgtg ggtcagggtg gcagtggcag gccgctcaac tatgaaacca
      661 atgcccaggg ggctgtggct cagcctggct atggagcagt gagaggcaac aaccagaatt
      721 cagggtgtac caacccccca ccttctgact cccacgaaag cttcagcgac tctgggggaa
      781 gcagcaatgg cggcagtcat ggtggccaag gcaaccaagg cagcaatggt cagggcaaca
      841 gcggcggtaa cagcggccaa ggcagcagtg gcagcagtgg caacagtggc aacaacgagg
      901 gcagcggtgg ccacagtggt aacagcggcg gcaacagcgg ttctgggtcc cgggacctgg
      961 aaacgtctaa ttttgatgat ggctattcag tttccagggg aactagctca tcctccggca
     1021 gcagaggtgg tagtggtggt ggtggaaaca gacccgagtg taacaaccca gggaatgacg
     1081 tgcgcatggc tggaggatct gggagtcagg aaagtaaaga aagcagccat ctccttggag
     1141 gctcccatga ctaccagggg cacgggtccg ggcacgggtc caatggtggc aatgtacaaa
     1201 gagatgctgt cagtggactc aacaccatga actccgatgc atcttccttg cctttcaact
     1261 tggacaattt ctgggagaat tttaaatcca agatgggttt cattaactgg gatgccataa
     1321 acaagggtcg aggcccggct cccagcactc gtgccttact ctacttccgc agactgtggg
     1381 agaatttcaa acgcaacact cctttcttca actggaaaca gattgagggc tcagatctgt
     1441 catctctgca gaagagggca ggtggtgctg accagttttc tcagccggaa gcagcaagac
     1501 aagatctgtc agctgagtca gccaagaact actacaacaa cgcccaggtg aatcctactt
     1561 acaactggca atactatacc aagaccaccc ccaaggcggg agtcacacct tcatcctcgg
     1621 cttcccgggc acaacctggc ctgctgaagt ggctgaagtt ttggtagaac attccatctg
     1681 gtcccagccg actcctcctg aaagtaggca ggtcttcagg gagcttgact gtccttaccc
     1741 acagtcctct ctgatgcggc tgacctacct gggcattcca tgcctgtcat ctcacctggg
     1801 gacctggttt atctgtcctc atcctccctg tttgactgta gtgtcttcga gactaatcag
     1861 cttcgttgga taaccagcca gctcttcagc tcttcttcta tatgtgagcg gaagtcccca
     1921 gaaggacgca gcaggaattc ctactctcaa gtttctctgt ggaaataaaa catgattctt
     1981 tgtttaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//
