LOCUS       NM_022849               4651 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus deleted in malignant brain tumors 1 (Dmbt1),
            mRNA.
ACCESSION   NM_022849 XM_577842
VERSION     NM_022849.3
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4651)
  AUTHORS   Ge,C., Zhang,Y., Jia,H., Luo,Y., Zu,Y., Yang,Z., Jia,L., Wang,J.
            and Du,Q.
  TITLE     [Expression and role of deleted in malignant brain tumor protein 1
            in acute respiratory distress syndrome rats induced by sepsis]
  JOURNAL   Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 35 (2), 152-157 (2023)
   PUBMED   36916375
  REMARK    GeneRIF: [Expression and role of deleted in malignant brain tumor
            protein 1 in acute respiratory distress syndrome rats induced by
            sepsis].
REFERENCE   2  (bases 1 to 4651)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   3  (bases 1 to 4651)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   4  (bases 1 to 4651)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   5  (bases 1 to 4651)
  AUTHORS   End,C., Bikker,F., Renner,M., Bergmann,G., Lyer,S., Blaich,S.,
            Hudler,M., Helmke,B., Gassler,N., Autschbach,F., Ligtenberg,A.J.,
            Benner,A., Holmskov,U., Schirmacher,P., Nieuw Amerongen,A.V.,
            Rosenstiel,P., Sina,C., Franke,A., Hafner,M., Kioschis,P.,
            Schreiber,S., Poustka,A. and Mollenhauer,J.
  TITLE     DMBT1 functions as pattern-recognition molecule for poly-sulfated
            and poly-phosphorylated ligands
  JOURNAL   Eur J Immunol 39 (3), 833-842 (2009)
   PUBMED   19189310
REFERENCE   6  (bases 1 to 4651)
  AUTHORS   Holmskov,U., Mollenhauer,J., Madsen,J., Vitved,L., Gronlund,J.,
            Tornoe,I., Kliem,A., Reid,K.B., Poustka,A. and Skjodt,K.
  TITLE     Cloning of gp-340, a putative opsonin receptor for lung surfactant
            protein D
  JOURNAL   Proc Natl Acad Sci U S A 96 (19), 10794-10799 (1999)
   PUBMED   10485905
REFERENCE   7  (bases 1 to 4651)
  AUTHORS   Mollenhauer,J., Wiemann,S., Scheurlen,W., Korn,B., Hayashi,Y.,
            Wilgenbus,K.K., von Deimling,A. and Poustka,A.
  TITLE     DMBT1, a new member of the SRCR superfamily, on chromosome
            10q25.3-26.1 is deleted in malignant brain tumours
  JOURNAL   Nat Genet 17 (1), 32-39 (1997)
   PUBMED   9288095
REFERENCE   8  (bases 1 to 4651)
  AUTHORS   De Lisle,R.C., Petitt,M., Huff,J., Isom,K.S. and Agbas,A.
  TITLE     MUCLIN expression in the cystic fibrosis transmembrane conductance
            regulator knockout mouse
  JOURNAL   Gastroenterology 113 (2), 521-532 (1997)
   PUBMED   9247472
REFERENCE   9  (bases 1 to 4651)
  AUTHORS   Li,X.J. and Snyder,S.H.
  TITLE     Molecular cloning of Ebnerin, a von Ebner's gland protein
            associated with taste buds
  JOURNAL   J Biol Chem 270 (30), 17674-17679 (1995)
   PUBMED   7629065
REFERENCE   10 (bases 1 to 4651)
  AUTHORS   De Lisle,R.C.
  TITLE     Characterization of the major sulfated protein of mouse pancreatic
            acinar cells: a high molecular weight peripheral membrane
            glycoprotein of zymogen granules
  JOURNAL   J Cell Biochem 56 (3), 385-396 (1994)
   PUBMED   7876332
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF540887.1.
            
            On or before Dec 25, 2009 this sequence version replaced
            XM_577842.2, NM_022849.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF540887.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5756307,
                                           SAMEA5760400 [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..4651
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..4651
                     /gene="Dmbt1"
                     /gene_synonym="Crpd; Dbmt1"
                     /note="deleted in malignant brain tumors 1"
                     /db_xref="GeneID:170568"
                     /db_xref="RGD:61984"
     CDS             17..4273
                     /gene="Dmbt1"
                     /gene_synonym="Crpd; Dbmt1"
                     /note="deleted in malignant brain tumors 1 protein;
                     crp-ductin; pancrin; hensin; ebnerin; deleted in malignant
                     brain tumors 1 protein-like"
                     /codon_start=1
                     /product="deleted in malignant brain tumors 1 protein
                     precursor"
                     /protein_id="NP_074040.2"
                     /db_xref="GeneID:170568"
                     /db_xref="RGD:61984"
                     /translation="MGISIVIFEICLLWGQILSTASQSRSSTPDWWNHGGTINDVIYD
                     TQETPEVTTTQVPDSTSIGTDSGLAVRLVNGGDRCRGRVEILYQGSWGTMCDDGTDSG
                     LAVRLVNGGDRCRGRVEILYQGSWGTMCDDSWDINDANVVCRQLGCGWALSAPGSAQF
                     GQGLGPIVLDDVACRGHEAYLWSCSHRGWLSHNCGHQEDAGVICSDSQTSSPTPGWWN
                     PGGTNNDVIYDTQETTETSQTSSPTPDWWNHGGTINDVIYDTQETTEGTDSGLAVRLV
                     NGGDRCRGRVEILYQGSWGTVCDDSWDINDANVVCRQLGCGWALSAPGSAQFGQGSGS
                     IVLDDVACRGHEAYLWSCSHRGWLSHNCGHQEDAGVICSYSQTSSPTPDSQTSSPTPG
                     WWNPGGTNNDVSYGPEQTTDATDSGLAVRLVNGGDRCQGRVEILYQGSWGTVCDDSWD
                     TKDANVVCRQLVCGWALSAPGSAHFGQGSGSIVLDDVACTGHEAYLWSCSHRGWLSHN
                     CGHHEDAGVICSDAQTQSTTWPDMWPTTTPETTTDWWTTKYSSSVPTTQFPTIADWWT
                     TPSPEYTCGGLLTLPYGQFSSPYYPGSYPNNARCLWKIFVSSMNRVTVVFTDVQLEGG
                     CNYDYILVFDGPENNSSLIARVCDGFNGSFTSTQNFMSVVFITDGSVTRRGFQADYYS
                     TPISTSTTSPTTFPIVTDWWTTPSPEYTCGGLLTLPYGQFSSPYYPGSYPNNARCLWK
                     IFVPSMNRVTVVFTDVQLEGGCNYDYILGFDGPEYNSSLIARVCDGSNGSFTSTQNFM
                     SVVFITDGSVTRRGFQADYYSTPIRTSTTPPTTFPIITGNDSSLVLRLVNGTNRCEGR
                     VEILYRGSWVPCADDSWDINDANVVCRQLGCGSALSAPGNAWFGQGSGLIVLDDVSCS
                     GYESHLWNCRHPGWLVHNCRHVEDAGVICSLPDPTPSPGPVWTSPPFVNYTCGGFLTG
                     LSGQFSSPYYPGSYPNNARCLWNIEVPNNYRVTVVFRDVQLEGGCNYDYIEIFDGPHH
                     SSPLIARVCDGAMGSFTSTSNFMSVRFTTDHSVTRRGFRADYYSDFDNNTTNLLCLSN
                     HMRASVSRSYLQSMGYSSRDLVIPGWNVSYQCQPQITQREVIFTIPYTGCGTTKQADN
                     ETINYSNFLKAAVSNGIIKRRKDLHIHVSCKMLQNTWVNTMYITNNTVEIQEVQYGNF
                     DVNISFYTSSSFLYPVTSSPYYVDLDQNLYLQAEVLHSDTSLALFVDTCVASPHPNDF
                     SSLTYDLIRSGCIRDETYQSYSSPSPRITRFKFSSFHFLNRFPSVYLQCKLVVCRAND
                     VSSRCYRGCVVRSKRDVGSYQEKVDVVLGPIQLQSPSKEKRSLDLAVADVEKPASSQE
                     VYPTAAIFGGVFLALVVAVAAFTLGRKTRTARGQPPSTKM"
ORIGIN      
        1 gagaggaacc agcacaatgg ggatctccat cgttatcttt gaaatatgtc ttttgtgggg
       61 tcaaattctt tctacagctt ctcaatcaag aagttccaca cctgattggt ggaaccatgg
      121 gggcacaatt aatgatgtga tctacgacac tcaagaaacc ccagaagtga cgactactca
      181 agttcctgat tccacatcaa taggaacaga ttctggtttg gctgtgaggc tggtgaatgg
      241 aggagacagg tgtcggggtc gcgtggagat cctttaccag ggttcctggg gcaccatgtg
      301 tgatgacgga acagattctg gtttggctgt gaggctggtg aatggaggag acaggtgtcg
      361 gggtcgcgtg gagatccttt accagggttc ctggggcacc atgtgtgatg acagctggga
      421 catcaatgat gccaacgtgg tgtgcaggca gctgggctgt ggctgggcct tgtctgcccc
      481 aggaagtgcc cagtttggac agggtctggg tcccattgtt ctggatgacg tggcctgtag
      541 aggacatgag gcctatctgt ggagctgctc ccaccgaggc tggctctctc ataactgtgg
      601 acatcaggag gatgctggag tgatctgctc agattctcaa acaagcagtc ccacacccgg
      661 ttggtggaac cccgggggca caaataacga tgtgatctac gacactcaag aaaccacaga
      721 aacttctcaa acaagcagtc ccacacctga ttggtggaac catgggggca caattaatga
      781 tgtgatctat gacactcaag aaaccacaga aggaacagat tctggtttgg ctgtgaggct
      841 ggtgaatgga ggagacaggt gtcggggtcg tgtggagatc ctttaccagg gttcctgggg
      901 caccgtgtgt gacgacagct gggacatcaa tgatgccaac gtggtgtgca ggcagctggg
      961 ctgtggctgg gccttgtctg ccccaggaag tgcccagttt ggacagggct ctgggtccat
     1021 tgttctggat gacgtggcct gtagaggaca tgaggcctat ctgtggagct gctcccaccg
     1081 aggctggctc tctcataact gtggacatca ggaggatgct ggagtcatct gttcatattc
     1141 tcaaacaagc agtcccacac ccgattctca aacaagcagt cccacacccg gttggtggaa
     1201 ccccgggggc acaaataacg atgtgtccta tggacccgaa cagaccacag acgcaacaga
     1261 ttctggtttg gctgtgaggc tggtgaatgg aggagacagg tgtcagggtc gtgtggagat
     1321 cctttaccag ggttcctggg gtaccgtgtg tgacgacagc tgggacacca aggatgccaa
     1381 cgtggtgtgc aggcagctgg tctgtggctg ggccttgtct gccccaggaa gtgcccactt
     1441 tggacaaggc tctggatcca ttgttctgga tgacgtggcc tgtacaggac atgaggccta
     1501 tctgtggagc tgctcccacc gaggctggct ctctcataac tgtggccacc atgaggatgc
     1561 tggagtcatc tgttcagatg cccaaaccca gagcacaacc tggccagata tgtggcctac
     1621 taccactcca gaaactacaa cagattggtg gactacaaaa tattcttcct ctgttcctac
     1681 aacacaattc cccaccatag ccgattggtg gacaactcct tctccggaat acacctgtgg
     1741 aggtttactg accctaccct atgggcagtt ttccagccca tactaccctg gaagctatcc
     1801 taacaatgcc agatgtttgt ggaaaatttt cgtctccagc atgaaccgtg tgacagtggt
     1861 cttcacagat gtgcagcttg aaggaggttg caactatgac tacatcctgg tttttgatgg
     1921 ccctgaaaac aattcttctc tcattgctcg ggtttgtgat gggttcaatg gatctttcac
     1981 ctcaacccag aacttcatgt ctgtagtctt tatcacggat ggcagtgtca cgaggagagg
     2041 gttccaagct gactactact ccactcctat cagcaccagc acaacctctc caacgacgtt
     2101 cccgatcgtt actgattggt ggacaactcc ttctccggaa tacacctgtg gaggtttact
     2161 gaccctaccc tatgggcagt tttccagccc atactaccct ggaagctatc ctaacaatgc
     2221 cagatgtttg tggaaaattt tcgtccccag catgaaccgt gtgacagtgg tcttcacaga
     2281 tgtgcagctt gaaggaggtt gcaactatga ctacatcctg ggttttgatg gtcctgaata
     2341 caattcttct ctcattgctc gggtttgtga tgggtccaat ggatctttca cctcaaccca
     2401 gaacttcatg tctgtagtct ttatcacgga tggcagtgtc acgaggagag ggttccaagc
     2461 tgactactac tccactccta tcaggaccag cacaactcct ccaacgacgt tcccgatcat
     2521 tactggaaat gattcttcat tggtgctgag gctggtaaat ggaacaaacc ggtgtgaggg
     2581 ccgagtggag atcttgtaca gaggctcttg ggtaccgtgt gccgacgaca gctgggacat
     2641 caatgatgcc aatgtggtct gcagacagct cggttgtggc tctgctctgt ctgctccagg
     2701 aaatgcttgg tttggtcagg gttcagggct cattgtcctg gatgatgtgt cttgctctgg
     2761 gtatgagtcc cacctgtgga attgtcgtca ccctggctgg cttgttcata attgtcgtca
     2821 tgttgaggat gcaggagtca tttgctcact ccctgatccg actccctctc ctggtccagt
     2881 ttggacaagt cctccttttg taaactatac ttgtggaggt ttcctgactg gactctctgg
     2941 gcaattttct agcccatact accctgggag ctatcctaat aatgccagat gtttgtggaa
     3001 cattgaagtc ccaaacaact accgcgtgac tgtggtcttc agagatgtgc agctggaagg
     3061 gggctgcaac tatgactata tagagatttt tgatggcccc caccacagtt cacctctcat
     3121 tgcccgggtt tgtgatgggg ccatgggctc tttcacttca acatccaact tcatgtcagt
     3181 tcgcttcacc actgatcaca gtgttactcg aagagggttc cgggctgact actactcaga
     3241 ctttgacaat aataccacca atctcctttg tctgtcaaat cacatgagag ccagtgtgag
     3301 caggagctac cttcagtcca tgggctactc ctccagggat cttgtcattc ctggttggaa
     3361 cgtgagttac cagtgtcagc ctcagataac acaaagggag gtcatattca caattcccta
     3421 cacaggctgc ggtactacca aacaggctga caacgagacc atcaactact ccaacttcct
     3481 caaagcggct gtttcaaatg gcatcatcaa aaggagaaag gatctccaca tccatgtcag
     3541 ctgcaagatg cttcagaaca cctgggtcaa caccatgtac atcaccaaca acacagtcga
     3601 gatccaggaa gtccagtatg gcaattttga cgtgaatatt tccttttata catcctcctc
     3661 cttcttgtat ccagtgacca gcagcccata ttatgtggat ctggaccaga atttgtacct
     3721 tcaggccgaa gtcctccatt cggatacctc tttggctctg tttgtggaca cctgtgtggc
     3781 ttcgccacat cccaatgact tctcgtcttt gacatatgat ctcatcagga gtggatgcat
     3841 acgagatgaa acttaccaat cttactcctc gccctcacca cgcatcaccc gctttaaatt
     3901 cagttctttc cacttcctga accgcttccc ctcagtatac ctacagtgta aactggtggt
     3961 ttgtcgagca aacgatgtct cctcacggtg ctacagagga tgtgtagtaa ggtccaagag
     4021 ggatgtaggc tcctaccaag aaaaggtgga tgttgttctg ggacccatcc agttgcaatc
     4081 tcccagcaaa gaaaagagga gtctcgactt ggcagtggca gatgtggaga agccagccag
     4141 ctcccaggag gtctatccca ctgcagccat ctttggtgga gtcttcctgg ccctggttgt
     4201 agctgtggca gccttcacac tgggaaggaa gacacgcact gcccgtggtc aacctccaag
     4261 tactaagatg tgaagcaaaa caacccagac attggtccca aatgcataga ttcccagaaa
     4321 agatggaagt caggagtgtc taatgcctgg cacccagata cacgatgact aggcttccct
     4381 tagcacaaat gtgtggccga gtatgatcag atggtaaaga agaaaggtgg gggccaagtt
     4441 ttcccagggt ctagaggctg aaggctggga agaatgtcat aggagaatga gatcagtgtc
     4501 tacaataaca ggcaactgtg agccaaacat tggcatcacc atcctttctc tagctagaat
     4561 ttccctttcc cccttttata ctgacttttt tgaactgtag tgttaaatgg acctttccgt
     4621 acaacaaact aaaataaaga atctttttcc a
//
