LOCUS       NM_001109145            1140 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus dickkopf like acrosomal protein 1 (Dkkl1), mRNA.
ACCESSION   NM_001109145 XM_001080698 XM_574445
VERSION     NM_001109145.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1140)
  AUTHORS   Kohn MJ, Sztein J, Yagi R, DePamphilis ML and Kaneko KJ.
  TITLE     The acrosomal protein Dickkopf-like 1 (DKKL1) facilitates sperm
            penetration of the zona pellucida
  JOURNAL   Fertil Steril 93 (5), 1533-1537 (2010)
   PUBMED   19596312
REFERENCE   2  (bases 1 to 1140)
  AUTHORS   Reynard LN, Cocquet J and Burgoyne PS.
  TITLE     The multi-copy mouse gene Sycp3-like Y-linked (Sly) encodes an
            abundant spermatid protein that interacts with a histone
            acetyltransferase and an acrosomal protein
  JOURNAL   Biol Reprod 81 (2), 250-257 (2009)
   PUBMED   19176879
REFERENCE   3  (bases 1 to 1140)
  AUTHORS   Dakhova O, O'Day D, Kinet N, Yucer N, Wiese M, Shetty G and Ducy P.
  TITLE     Dickkopf-like1 regulates postpubertal spermatocyte apoptosis and
            testosterone production
  JOURNAL   Endocrinology 150 (1), 404-412 (2009)
   PUBMED   18818293
REFERENCE   4  (bases 1 to 1140)
  AUTHORS   Kohn MJ, Kaneko KJ and DePamphilis ML.
  TITLE     DkkL1 (Soggy), a Dickkopf family member, localizes to the acrosome
            during mammalian spermatogenesis
  JOURNAL   Mol Reprod Dev 71 (4), 516-522 (2005)
   PUBMED   15892050
REFERENCE   5  (bases 1 to 1140)
  AUTHORS   Bennett CN, Ross SE, Longo KA, Bajnok L, Hemati N, Johnson KW,
            Harrison SD and MacDougald OA.
  TITLE     Regulation of Wnt signaling during adipogenesis
  JOURNAL   J Biol Chem 277 (34), 30998-31004 (2002)
   PUBMED   12055200
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_574445.2, XM_001080698.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1140
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..1140
                     /gene="Dkkl1"
                     /gene_synonym="RGD1563523"
                     /note="dickkopf like acrosomal protein 1"
                     /db_xref="GeneID:499150"
                     /db_xref="RGD:1563523"
     exon            1..354
                     /gene="Dkkl1"
                     /gene_synonym="RGD1563523"
                     /inference="alignment:Splign:2.1.0"
     exon            355..524
                     /gene="Dkkl1"
                     /gene_synonym="RGD1563523"
                     /inference="alignment:Splign:2.1.0"
     CDS             372..1064
                     /gene="Dkkl1"
                     /gene_synonym="RGD1563523"
                     /note="dickkopf-like protein 1; dickkopf-like 1"
                     /codon_start=1
                     /product="dickkopf-like protein 1 precursor"
                     /protein_id="NP_001102615.1"
                     /db_xref="GeneID:499150"
                     /db_xref="RGD:1563523"
                     /translation="MGRLGVLLLLLPLAFVCASAVPIHDADSQQNSSGFLGLQSLLQS
                     FSRLFLKNDLLQDLDNFFSSPMDFRDLPRNFHQEQNQEHRMGNHTLSSHLQIDKMTDN
                     QTGEVLISEKVVASIEPEVNPEGDWKVPKVEAKEALVPVQKATDSLHPEPRRVAFWIM
                     KMPRRRTQPDVQDGNRWLTEKRHRMQAIRDGLRGGAHEDNLEEGVHVPQHAKVPIRKT
                     HFLYIFRPSQQL"
     exon            525..665
                     /gene="Dkkl1"
                     /gene_synonym="RGD1563523"
                     /inference="alignment:Splign:2.1.0"
     exon            666..755
                     /gene="Dkkl1"
                     /gene_synonym="RGD1563523"
                     /inference="alignment:Splign:2.1.0"
     exon            756..1140
                     /gene="Dkkl1"
                     /gene_synonym="RGD1563523"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 taaatgcctg gtttgtgagt aaggtcacca gatgtgggcg tggccttcca tgaggaggtc
       61 tagcttaaga ggcgtggtta atgaacaata cagatgtgga tttgccagaa acatgatggt
      121 ggagtagtga ggattatggt ggagtagtaa ggattctagg tgacagtggg tggtgggcgt
      181 ggtgagacaa tggggcgtgg ccagtctcgc ggagaggtgg cacccaacga acgaacgctc
      241 cagtaatttg cccaggctcg agaccagaac tggattttaa ctgcccgtat ccggcggtgt
      301 ccggagccgg gtggccgagc tgcagtccag gagaaggcgc gaatgtaggc aaagcctccc
      361 acacaactgc aatgggtcga ctgggagtcc tgttgctgct gctccccttg gcctttgtgt
      421 gcgcctctgc tgtaccgatc catgatgccg actctcagca gaactcctcc ggatttctgg
      481 gccttcagag tcttcttcaa agctttagtc gactgttcct aaaaaatgac ctgctacaag
      541 acctggacaa cttcttctcc tcccccatgg acttccgaga ccttcctagg aacttccatc
      601 aggaacagaa ccaggagcac agaatgggaa accataccct ctccagccac ctacagatag
      661 acaagatgac tgacaaccag acaggggagg tgctcatctc cgagaaggtg gtggcttcca
      721 ttgagccaga agtgaaccca gaaggtgact ggaaggtgcc caaagtggag gcgaaagagg
      781 ccctggtgcc cgtgcagaag gccaccgaca gtttgcaccc agagccccgg cgggtggctt
      841 tctggattat gaagatgcca agacggagga cccagccaga tgtccaggac ggaaaccgct
      901 ggctcacaga aaagcggcac cgcatgcagg ccatccggga tgggctccga ggaggcgccc
      961 atgaggacaa ccttgaggaa ggggtccatg tgccccaaca cgccaaggtg cccatccgaa
     1021 agacacactt tctctacatc ttcaggccat cccagcagct ataaggtggg gaccgtgtat
     1081 ccctgcatgt cctacaccct accccaacac catatggaaa taaagttttt tcttacatct
//
