LOCUS       NM_001107992            6304 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus dispatched RND transporter family member 3
            (Disp3), mRNA.
ACCESSION   NM_001107992 XM_001075091 XM_003750087 XM_003754115 XM_233671
VERSION     NM_001107992.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6304)
  AUTHORS   Zikova,M., Konirova,J., Ditrychova,K., Corlett,A., Kolar,M. and
            Bartunek,P.
  TITLE     DISP3 promotes proliferation and delays differentiation of neural
            progenitor cells
  JOURNAL   FEBS Lett 588 (21), 4071-4077 (2014)
   PUBMED   25281927
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On or before Aug 16, 2019 this sequence version replaced
            XM_003750087.4, XM_003754115.4, NM_001107992.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on orthologous alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.2208860.1,
                                           SRR26643298.30182.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-207               JAXUCZ010000005.1  164003744-164003950 c
            208-1183            JAXUCZ010000005.1  163986763-163987738 c
            1184-1403           JAXUCZ010000005.1  163986014-163986233 c
            1404-1540           JAXUCZ010000005.1  163977339-163977475 c
            1541-1675           JAXUCZ010000005.1  163976431-163976565 c
            1676-1836           JAXUCZ010000005.1  163975765-163975925 c
            1837-1976           JAXUCZ010000005.1  163974598-163974737 c
            1977-2125           JAXUCZ010000005.1  163973996-163974144 c
            2126-2287           JAXUCZ010000005.1  163973657-163973818 c
            2288-2449           JAXUCZ010000005.1  163972572-163972733 c
            2450-2563           JAXUCZ010000005.1  163970777-163970890 c
            2564-2700           JAXUCZ010000005.1  163969894-163970030 c
            2701-2885           JAXUCZ010000005.1  163968590-163968774 c
            2886-3016           JAXUCZ010000005.1  163966783-163966913 c
            3017-3189           JAXUCZ010000005.1  163966510-163966682 c
            3190-3316           JAXUCZ010000005.1  163965596-163965722 c
            3317-3462           JAXUCZ010000005.1  163964896-163965041 c
            3463-3622           JAXUCZ010000005.1  163959963-163960122 c
            3623-3736           JAXUCZ010000005.1  163959191-163959304 c
            3737-3903           JAXUCZ010000005.1  163958541-163958707 c
            3904-6304           JAXUCZ010000005.1  163955160-163957560 c
FEATURES             Location/Qualifiers
     source          1..6304
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..6304
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /note="dispatched RND transporter family member 3"
                     /db_xref="GeneID:313705"
                     /db_xref="RGD:1305820"
     exon            1..207
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            208..1183
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     CDS             211..4266
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /note="patched domain-containing protein 2; patched domain
                     containing 2"
                     /codon_start=1
                     /product="protein dispatched homolog 3"
                     /protein_id="NP_001101462.2"
                     /db_xref="GeneID:313705"
                     /db_xref="RGD:1305820"
                     /translation="MDSEDDPLLQDVWLEEEQQEEETSDEACRAVPGPGLHSGAQGCW
                     RRWTLPSRPPTLGFWSTLGWAFTNPCCAGLVLFLGCSIPMVLSAFMFLYYPPLDIDIS
                     YNAFEIRNHEASQRFDALALALKSQFGSWGRNRRDLADFTSETLQRLISEQLQQLHLG
                     NHSRPASRAPRSDPRDTAATQRSATNTRERRRREAPPPEGQVANQSRARRGASRWDYS
                     RTYVSANTQTHAHWRIELIFLARGDAERNIFTSERLVTIHEIERKIMDHPGFREFCWK
                     PHEVLKDLPLGSYSYCSPPSSLMTYFFPTERGGKIYYDGMGQDLADIRGSLELAMTHP
                     EFYWYVDEGLSVDNLKSSLLRSEILFGAPLPNYYSVDDRWEEQRAKFQSFVVTYVAML
                     AKQSTSKVQVLYGGTDLFDYEVRRTFNNDMLLAFISSSCIAALVYILTSCSVFLSFFG
                     IASIGLSCLVALFLYHVVFGIQYLGILNGVAAFVIVGIGVDDVFVFINTYRQATHLED
                     PQLRMIHTIQTAGKATFFTSLTTAAAYAANVFSQIPAVHDFGLFMSLIVTCCWLAVLF
                     TMPAALGLWSLYVAPLESSCQSSCHQKCGRKSSLHFPGDLFTAPERAGCGPAQGPLPY
                     LDDDIPLLNVEDEPVSLELGDVSLVSVHCEGLQPTPDGNSRGQLLAQLQELLHRWVLW
                     AAVKSRWVIVGLFASILILSLVFASRLRPASRAPLLFRPDTNIQVLLDLKYNLSAEGI
                     SCITCSGLFQEKPHSLQNNVRTSLEKKKRGSGVSWASRPETTAQESMSTVYISKVKSK
                     GHPAVYRLSLNASLPAPWQAVSPGDGEVPSFQVYRAPFGDFTKKLTACMSTVGLLQAA
                     SPSRKWMVTALACDARRGWKFDFSFYVATKEQQHTRKLYFAQSHKPPFHGRLCVAPPG
                     CLLSSSPDGPTKGFFYVPSDRVPKARISATFGFNPCVNTGCGKPAVRPLVDTGAMVFV
                     VFGIIGINRTQQMDNHVIGDPGSVIYDSSFDLFKEIGHLCRLCKAIAGNSELVKPGGA
                     QCLPSGYSISSFLQMLHPECKELPEPNLLPGQLSHGAVGVKEGRVQWISMAFESTTYK
                     GKSSFQTYSDYLRWESFLRQQLQTFPEGSALRRGFQTCEHWKQIFMEIIGVQSALYGL
                     VLSLLICVAAVAVFTTHVLLLLPVLLSILGIVCLVVTIMYWSGWEMGAVEAISLSILV
                     GSSVDYCVHLVEGYLLAGENLPPQQAEDASSQRQWRTLEAVRHVGVAIVSSALTTVIA
                     TVPLFFCIIAPFAKFGKIVALNTGVSILYTLTVSTALLGIMAPGSFTRTRTSFLKALG
                     AVLLAGALGLGTCLVLLRSGYKIPLPSGATL"
     exon            1184..1403
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            1404..1540
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1675
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            1676..1836
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            1837..1976
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            1977..2125
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            2126..2287
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            2288..2449
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            2450..2563
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            2564..2700
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            2701..2885
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            2886..3016
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            3017..3189
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            3190..3316
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            3317..3462
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            3463..3622
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            3623..3736
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            3737..3903
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
     exon            3904..6304
                     /gene="Disp3"
                     /gene_synonym="Ptchd2; RGD1305820"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgtgcgcgc tggggacgta gttgtcacgg acctggccgt ggtctgcacg ccggcgagcg
       61 gagcttgggg gccgttggcc tcctatagct ctgaggacct ttccttctga aattccctac
      121 aagggacaag tgttcgaagc ggggtggtcg aagtccctta acccctgagg cacccgtgta
      181 tcagcctagc tcgtctcgga cagcgagggt atggactcag aggatgaccc cctgctgcag
      241 gatgtatggc tagaagagga acagcaggaa gaggagactt cagatgaggc atgcagggct
      301 gtccccggtc cagggctgca ctccggagca cagggctgct ggcgccgctg gacactgccc
      361 tccaggcccc cgaccttggg gttctggagt accctgggct gggccttcac caacccatgc
      421 tgcgcagggc tggtgctgtt tcttggctgc agcatcccca tggtgctgtc tgccttcatg
      481 ttcctctact acccgcccct ggacatcgac atctcctaca acgcctttga gatccgcaac
      541 cacgaggcgt cacagcgctt cgacgccctg gccttggccc tcaagtccca gtttggatct
      601 tgggggcgca acaggcgcga cctggcggac ttcacctctg agacgctgca gcgcctcatc
      661 tcagagcagc ttcagcagct gcacctgggg aatcattctc gacctgcgtc ccgagctcct
      721 cgctcagacc ccagggacac tgctgccact cagagatcag caaccaatac gagggagcga
      781 cgtcgcaggg aggctccgcc tccggagggt caggtagcca accagagccg agcccgtcgg
      841 ggcgcctctc gctgggatta ctcgcgtacc tatgtgagcg ccaacaccca gacgcacgcc
      901 cattggcgaa tcgagctcat ctttctggcg cgcggagatg cggagcgcaa cattttcacc
      961 agcgagcgtc tggtgacgat ccacgagatc gagcgtaaaa tcatggacca ccccggtttc
     1021 cgggagttct gctggaagcc gcatgaggtg ctcaaggacc tgccactggg ctcctattcc
     1081 tactgctcac cacctagttc actcatgact tacttcttcc ccactgagag gggcggaaag
     1141 atctactacg acggcatggg ccaggacctg gcagatatcc gaggctccct agaactggcc
     1201 atgactcacc ctgagttcta ctggtatgtg gatgaggggc tgtctgtgga taatctgaag
     1261 agctcccttc tgcgcagcga gatcctgttt ggagcgccac tccccaacta ctactcagtg
     1321 gacgatcgct gggaggaaca gagggccaag ttccagagct ttgtagtcac atatgtggcc
     1381 atgctagcca agcagtctac tagcaaagtc caggtcctct atggggggac agacctcttc
     1441 gactatgagg tacgccggac cttcaataac gacatgctcc tcgccttcat tagcagcagc
     1501 tgcatcgctg cccttgtcta catcctaacc tcctgctcag tgttcctgtc cttctttggg
     1561 attgccagca tcggtctcag ttgcctggtg gcactctttc tctaccatgt ggtctttggc
     1621 atccagtact tgggcatcct caatggagtg gccgccttcg tgatcgtggg catcggtgtg
     1681 gacgatgtct ttgtattcat caacacatac cgccaggcta cacacctgga agacccccaa
     1741 ctgcggatga tccacaccat ccagacggca ggcaaagcca ccttcttcac ctcgctgacc
     1801 actgctgccg cctatgcggc caacgtcttt tcccagatcc cagctgtcca tgacttcggc
     1861 ttgttcatgt ccctcattgt gacctgctgc tggctggccg tgctgttcac catgcctgcg
     1921 gccctgggcc tctggagcct ctacgtggca cccctggaga gctcctgcca gagcagctgc
     1981 caccagaagt gcggccgcaa gagctccttg cattttcctg gggacctgtt tacagctcca
     2041 gagcgggctg ggtgtggccc tgctcagggc cccctaccct acctggatga tgacatcccc
     2101 ttgctgaacg tggaggatga accagtatct ctagagctgg gagatgtatc actggtctct
     2161 gtgcactgtg agggtctgca gcccacccct gacgggaaca gcaggggcca gctcctcgcc
     2221 cagctgcaag agctgctgca ccgctgggtc ttatgggcag ctgtcaagag ccgctgggtg
     2281 attgtagggc ttttcgcctc catccttatc ctgtccctgg tgttcgccag ccggctccgt
     2341 cccgccagcc gagccccact gctcttccgg cctgacacca acattcaggt gctgctggac
     2401 ctcaagtaca acctgagtgc ggagggaata tcctgcatca cctgctcagg tctgttccag
     2461 gagaagcccc acagcctgca gaacaatgtc aggacatccc tggagaagaa gaagcgaggt
     2521 tctggggttt cctgggccag ccggcctgag accacggcac aggagtccat gagcactgtg
     2581 tacatctcca aagtgaagag caaaggccac ccagctgtct acagactttc cctcaatgcc
     2641 agcctaccag cgccctggca agctgtgtcc cctggagatg gagaggtgcc ctccttccag
     2701 gtgtatagag cgccttttgg tgacttcacc aagaagctga ccgcttgtat gtctacagta
     2761 gggctgctcc aggcggcgag cccctcccgc aagtggatgg tgacggcttt ggcctgtgat
     2821 gccaggaggg gctggaagtt tgacttcagc ttttacgtgg ccaccaagga gcaacagcac
     2881 actcggaagc tgtactttgc tcagtctcac aagcccccct tccacgggcg cctgtgtgtg
     2941 gcgccacctg gatgtctgct cagctccagc cctgacgggc ctaccaaagg cttcttctat
     3001 gtgccgagtg acagagtgcc caaggcccgc atctctgcca cctttggctt caacccctgt
     3061 gtgaacacgg gctgtgggaa gcctgcggtg cggccgctgg tggatacagg agccatggtc
     3121 tttgtggtgt tcggtatcat cggcatcaac cgcacccagc agatggacaa ccacgttatt
     3181 ggggacccgg gcagcgtcat ctacgacagc agctttgacc tcttcaaaga gattgggcac
     3241 ctgtgtcgcc tctgcaaggc catcgcgggc aactcggagc tggtgaagcc aggcggggcc
     3301 cagtgcttgc cctcagggta cagcatctct tccttcctgc agatgttgca ccccgagtgc
     3361 aaggagctgc ctgagcccaa cttgctgcca gggcagctat cccatggggc agtgggcgtc
     3421 aaagagggcc gtgtgcagtg gatctccatg gcctttgagt cgaccacgta caagggcaag
     3481 tcctccttcc agacctactc ggactacttg cgttgggaga gcttcctccg gcagcagctg
     3541 cagaccttcc ctgagggctc agccctgcgc cgaggcttcc agacctgtga gcactggaaa
     3601 caaatcttca tggagatcat aggggtacag agtgcccttt atggcctggt cctctccctg
     3661 ctcatctgtg tggccgcggt ggccgtgttc accacccacg tcctcctcct gctgcctgtg
     3721 ctcctgagta tcctaggcat cgtctgcctc gtggtgacca tcatgtactg gagtggctgg
     3781 gagatgggtg ctgtagaggc catctctctg tccatcctgg ttggctcctc tgtggattac
     3841 tgtgtccatc tggtagaagg ttacctgctg gctggggaga acctgccccc acagcaggct
     3901 gaggatgcca gctctcagcg acagtggagg acattggagg ccgtccggca cgtgggcgtg
     3961 gccatcgtat ccagtgcact caccaccgtc atcgccactg tcccactctt cttctgcatt
     4021 atcgccccgt tcgccaagtt cgggaagatc gtggcgctca acacgggcgt gtccatcctc
     4081 tacacactca ctgtcagcac cgccctactg ggcatcatgg cccccggttc cttcacccgt
     4141 accaggactt ccttcctcaa ggccctgggt gccgtgctgc tggcaggagc cctagggctg
     4201 ggcacctgtc tcgtgctcct gcgcagtggc tacaagatcc ccctgcccag cggggccacg
     4261 ctataactct gtgcttgcgt cctgactcat acaccttgcc ctgcagcagg ggatgagggg
     4321 atctgaaatg cagggactct cggttttctg gcccagttcc aggtagctcc actcacaggt
     4381 ttcatggaac tgggaccccg agctgtgtgg gacacacccc cttcagccca gctcagactg
     4441 gaagtcaagt cagatacccc cacacaatct gggccccctc gctgaagtct gcctggccct
     4501 ggaagatact aaccatcttc ccatacctgg tctccaccaa gcaggcggct tctctcctct
     4561 cacactgctt cagtgtccgt gacctgcttg ggcccgcatt tcagggccag ccactctaca
     4621 gatgtggaaa ccagggcacc aggaggcagg aactgccctg tggctggatc agggcggagc
     4681 cagagttgcc tcatagcaca ggcctcccta tggagggaaa gagcacagca gatccaggac
     4741 agggggccca cccacccccc agctctatgc agccagtgtt tgttgaccct gctgttgcgg
     4801 tccaagccag cagagacaga ggcatttctt gggatcgtgc atgtcctagc cccagccaca
     4861 gcctccgggg cacctcaaaa acccctccct ggagctgcgg catccccaac agatccaaac
     4921 ctcgtcgccc ccacctgact gagagcggat gactggtgtg tggcggggcg ctacacacat
     4981 ggggaggagc cggccgtgcc tgccgcctgc ctgctcgtgg cagatggtcc ctattaaagt
     5041 gagacgaagc tgcagaccgc tgccattaac acaagcattt tcagcctggc tggctccatc
     5101 attttcttaa aattgacata actaagtgtt cacccacagc ctgatacaga gggtggcacc
     5161 ggacccagac ggacacacga gtgggtagag ggtgtccagt acagaggtgg gaatacttgg
     5221 gctcagtgtg aggccggggc ctcctagcgg gaagtgggag gggccctgga gacgtttgtg
     5281 cctttacgga gcccatttgg gccccaccgt tgggcatttt tgaaagctta gcattgtgac
     5341 agccaccaga cttctttccg ggcacagacg ttgtgccttc tgggtcttat aaagctggac
     5401 atagatcgaa caggacagtt ctgagatcag gacagatccc tgagggtgag gaaggaaccc
     5461 gaggtggtct acacacccgt tcacctggtc actagtaact atgaaaggga gggctggggt
     5521 gcaagacaga gaccactgcg tccttgccca catattcctg gtgtagcctg atgcccagtg
     5581 cttgttgggg aaatatcaaa cctttggacc caccatccac cgtgaagaaa tgaatcgatc
     5641 aggcgggtac tggctggcat gtaacacaac agacgccctt ctcggagttg gtgttcattt
     5701 cctggggcgc cacgatggca ccacagatgt ctgcagcaga agaccctcag ctctgacagc
     5761 agggttgttc cctctgggaa tccaaagagg ggaatctggt ccaggcccgc tggctgctgg
     5821 gcatctgcta gtctccgtgt gtctgccatt tcatgttcgc attcctctaa gagcgacatc
     5881 tgtcatgctg gagttggccc cacccttatg acctcatcct aacctggttg gctgcagaga
     5941 ccccgcccca atgagcttct gtccatggag actaggtgtt aggaccgaag tataccccgt
     6001 gggggggggg ggacgacgca gggtcatcac aaacacagga gtcagatttg tgtgtgtgtg
     6061 tgtgtgttgg agggtcagtt tgagactggg tttctctgtg tggccttggc tgtcctggac
     6121 cctgctctgt agagcaggct gacctcaaac tcagaggact atctgcccct gtgctgggac
     6181 aaggcatgca tcaccacgct gggcaggaat cagctttttt tctaatcggt gtagatgcat
     6241 gcaagggacc caatgcctga gtcgtggttt tttttttttc tggatcctga gcccaacctg
     6301 gagc
//
