LOCUS       NM_001169578            1201 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus DIRAS family GTPase 2 (Diras2), mRNA.
ACCESSION   NM_001169578 XM_001053689 XM_225214
VERSION     NM_001169578.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1201)
  AUTHORS   Ogita,Y., Egami,S., Ebihara,A., Ueda,N., Katada,T. and Kontani,K.
  TITLE     Di-Ras2 Protein Forms a Complex with SmgGDS Protein in Brain
            Cytosol in Order to Be in a Low Affinity State for Guanine
            Nucleotides
  JOURNAL   J Biol Chem 290 (33), 20245-20256 (2015)
   PUBMED   26149690
  REMARK    GeneRIF: propose that isoprenylated Di-Ras2 forms a tight complex
            with SmgGDS in cytosol immediately after its synthesis, which
            lowers its affinity for guanine nucleotides.
REFERENCE   2  (bases 1 to 1201)
  AUTHORS   Kontani,K., Tada,M., Ogawa,T., Okai,T., Saito,K., Araki,Y. and
            Katada,T.
  TITLE     Di-Ras, a distinct subgroup of ras family GTPases with unique
            biochemical properties
  JOURNAL   J Biol Chem 277 (43), 41070-41078 (2002)
   PUBMED   12194967
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On or before Dec 18, 2009 this sequence version replaced
            XM_225214.2, XM_001053689.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR26643298.68624.1,
                                        SRR26360176.1792853.1 [ECO:0000345]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1201              JAXUCZ010000017.1  12909426-12910626
FEATURES             Location/Qualifiers
     source          1..1201
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1201
                     /gene="Diras2"
                     /note="DIRAS family GTPase 2"
                     /db_xref="GeneID:291006"
                     /db_xref="RGD:1305580"
     exon            1..1201
                     /gene="Diras2"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..632
                     /gene="Diras2"
                     /note="DIRAS family, GTP-binding RAS-like 2"
                     /codon_start=1
                     /product="GTP-binding protein Di-Ras2"
                     /protein_id="NP_001163049.1"
                     /db_xref="GeneID:291006"
                     /db_xref="RGD:1305580"
                     /translation="MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTY
                     RQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYE
                     QICEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKE
                     LFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM"
ORIGIN      
        1 ctcctggtca gtagctggaa ttctgaagca acatgccgga acagagcaat gactaccggg
       61 tggccgtgtt tggggcaggt ggcgttggca agagctccct ggttttgagg tttgtgaaag
      121 ggaccttcag ggagagctac atcccaactg tggaagacac ctaccggcag gtgatcagct
      181 gtgacaagag catctgtacg ctgcagatca ccgacacgac cgggagccac cagttcccgg
      241 ccatgcagcg gctgtccatc tccaagggcc acgccttcat cctggtctac tccattacca
      301 gccggcagtc cctggaggaa ctcaagccca tctatgagca gatctgcgag atcaaggggg
      361 atgtggagag catccccatc atgctggtgg ggaacaagtg tgacgagagc cccaaccgcg
      421 aggtccagag cagcgaggcg gaggccctgg cgcgcacgtg gaagtgtgcc ttcatggaga
      481 catcggccaa gctcaaccac aacgtcaagg aactctttca ggagctactg aacctggaga
      541 agcgcaggac cgtgagcctc cagatcgatg gcaagaagag caagcagcag aagaggaagg
      601 agaagctcaa gggcaagtgt gtggtcatgt gagaggcctt tgtgcagaaa gagctgctgc
      661 tgccctcagg gcctctctct tcctcccctc tgtgaacccc actgtcgtca gggcagcatg
      721 tccgatgccc gtgtgttaaa cattgcattt ggctgcgaca caccctgcaa atgtccttaa
      781 gaggcattcc acacgcccca ctagcccacc cctcaggaga cgcagaatct gggaagctct
      841 tagcatcccc gggagcggag gccagtcctg aatgggcttt agccattgga agatgagggg
      901 actcagagct gtggacccgg gagaaactga gggtactgtg taatgcatgt gcgtgtgaca
      961 tagctactgg taccacccca catcaggcaa cctagtttgg aagccactaa catctttggg
     1021 gggggggagg agcaggcagt cgaaggaagt gagaaacccg tggaccccag cggttcccat
     1081 gagtggattt ttagtgggat taaagattaa ataccacagt ccccatctaa gcgatgctca
     1141 tgccattcct actgacacac actgaggggg ttggccccct cattcctcaa agccttctta
     1201 g
//
