LOCUS       NM_001134472            4023 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus divergent protein kinase domain 2A (Dipk2a),
            mRNA.
ACCESSION   NM_001134472 XM_001068478 XM_236493
VERSION     NM_001134472.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4023)
  AUTHORS   Huang,J., Guo,J., Beigi,F., Hodgkinson,C.P., Facundo,H.T.,
            Zhang,Z., Espinoza-Derout,J., Zhou,X., Pratt,R.E., Mirotsou,M. and
            Dzau,V.J.
  TITLE     HASF is a stem cell paracrine factor that activates PKC epsilon
            mediated cytoprotection
  JOURNAL   J Mol Cell Cardiol 66, 157-164 (2014)
   PUBMED   24269490
REFERENCE   2  (bases 1 to 4023)
  AUTHORS   Beigi,F., Schmeckpeper,J., Pow-Anpongkul,P., Payne,J.A., Zhang,L.,
            Zhang,Z., Huang,J., Mirotsou,M. and Dzau,V.J.
  TITLE     C3orf58, a novel paracrine protein, stimulates cardiomyocyte
            cell-cycle progression through the PI3K-AKT-CDK7 pathway
  JOURNAL   Circ Res 113 (4), 372-380 (2013)
   PUBMED   23784961
REFERENCE   3  (bases 1 to 4023)
  AUTHORS   Takatalo,M.S., Tummers,M., Thesleff,I. and Ronnholm,R.
  TITLE     Novel Golgi protein, GoPro49, is a specific dental follicle marker
  JOURNAL   J Dent Res 88 (6), 534-538 (2009)
   PUBMED   19587158
REFERENCE   4  (bases 1 to 4023)
  AUTHORS   Takatalo,M., Jarvinen,E., Laitinen,S., Thesleff,I. and Ronnholm,R.
  TITLE     Expression of the novel Golgi protein GoPro49 is developmentally
            regulated during mesenchymal differentiation
  JOURNAL   Dev Dyn 237 (8), 2243-2255 (2008)
   PUBMED   18651652
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.20937.1,
                                           SRR26643290.30327.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760476, SAMN14984027
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-860               JAXUCZ010000008.1  103968602-103969461 c
            861-1164            JAXUCZ010000008.1  103956332-103956635 c
            1165-4023           JAXUCZ010000008.1  103950345-103953203 c
FEATURES             Location/Qualifiers
     source          1..4023
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..4023
                     /gene="Dipk2a"
                     /gene_synonym="Ab2-095; RGD1309079"
                     /note="divergent protein kinase domain 2A"
                     /db_xref="GeneID:315891"
                     /db_xref="RGD:1309079"
     exon            1..860
                     /gene="Dipk2a"
                     /gene_synonym="Ab2-095; RGD1309079"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..1496
                     /gene="Dipk2a"
                     /gene_synonym="Ab2-095; RGD1309079"
                     /note="deleted in autism protein 1"
                     /codon_start=1
                     /product="divergent protein kinase domain 2A"
                     /protein_id="NP_001127944.1"
                     /db_xref="GeneID:315891"
                     /db_xref="RGD:1309079"
                     /translation="MWRLVPLKLGRLSRALKLAALGSLLVLMLLHSPSLLASWQRNEL
                     ADRRFLQLNKCPACFGTSWCRRFLNGQVGFETWGRLRLLDFLNVKNVYFAQYGEPREG
                     GRRRVVLKRLGSQRELAQLDQSICKRATGRPRCDLLQAMPRTEFARLNGDVRLLTPEA
                     VEGWSDLVHCPSQRLLDRLVRRYAETKDSGSFLLRNLKDSERMQLLLTLAFNPEPLVL
                     QSFPSDEGWPFAKYLGACGRMVAVNYVGEELWSYFNAPWEKRVDLAWQLMEIAEQLTN
                     NDFEFALYLLDVSFDNFAVGPRDGKVIIVDAENVLVADKRLIRQNKPENWDVWYESKF
                     DDCDKEACLSFSKEILCARVTVDHNYYAVCQNLLSRHATWRGTSGGLLHDPPSEIAKD
                     GRLEALLDECTNPKKRYGRFQAAKELRGYLAQLSHNVR"
     exon            861..1164
                     /gene="Dipk2a"
                     /gene_synonym="Ab2-095; RGD1309079"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..4023
                     /gene="Dipk2a"
                     /gene_synonym="Ab2-095; RGD1309079"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagtcggag ggcggggagc tcggaggagg gcgcccggag ttgtggagac agccgatcgg
       61 gaagtcgccg cgcttggccg gcgcagcccg ttctcgggct tcttcgctgc cgccctccgt
      121 ctgcgccgcg ggcctcggcg ccgtggggcg gcccggggtg cgctcgcccg ccccggcccc
      181 ggccactgcc gcgcgcgggc gggatgtggc gcctggtgcc cctgaagctg ggccgcctgt
      241 cccgtgcact gaagctggcg gcgctcggca gcctgttggt gctgatgctg ctgcactcgc
      301 cgtcgctgct cgcctcttgg cagcgcaacg agctcgccga ccggcgtttc ctgcagctca
      361 ataagtgccc ggcgtgcttc ggcacgagct ggtgccgccg tttcctcaac ggccaggtgg
      421 gcttcgagac gtggggccgc ctgcgcctgc tggacttcct caacgtgaag aacgtgtact
      481 tcgcgcagta cggcgagccc cgcgagggcg gccgccggcg cgtggtgctc aagcgcctgg
      541 gttcgcagcg cgagctggcg cagctcgacc agagcatctg caagcgggcc accggccggc
      601 cgcgctgcga cctgctccag gccatgcccc gcaccgagtt cgcgcgtctc aacggcgacg
      661 tgcggctgct cacgccggag gcggtggagg gttggtcaga cctggtgcac tgcccctcgc
      721 agcgcttgct ggaccgcctg gtgcgccgct acgccgagac caaggactcg ggcagtttcc
      781 tgctgcgcaa cctcaaggac tcggagcgca tgcagctgct gctcaccctg gccttcaacc
      841 ccgagccgct ggtgctacag agttttccat ctgatgaagg ttggccattt gcaaagtatc
      901 tcggagcttg tggaagaatg gtggctgtaa attacgttgg agaagaactg tggagttatt
      961 ttaatgcacc atgggagaaa agagttgacc ttgcttggca gttaatggaa atagcagagc
     1021 agcttacaaa caatgacttt gaatttgcac tctacctcct ggacgtcagc tttgacaatt
     1081 ttgcagttgg tccaagagat gggaaggtaa tcattgtgga tgctgaaaat gttttagttg
     1141 ccgacaaaag attaattaga caaaataagc ctgagaattg ggatgtatgg tatgagagca
     1201 agtttgatga ctgtgacaag gaggcttgct tatcattttc gaaagaaatc ctttgtgctc
     1261 gtgtcactgt ggaccacaat tactatgctg tttgtcaaaa cctcttatct agacatgcca
     1321 cctggcgtgg cacttctgga ggactccttc atgatccacc aagtgaaatt gccaaagatg
     1381 gccgactgga ggccttgctg gatgagtgca ccaaccccaa gaagcgctat ggccgattcc
     1441 aggctgcaaa agaactgcga ggctatctag cacagttaag tcacaatgtg aggtagtcag
     1501 cagtgatctt ttccttttct ttgctgaaat agcactggca aaactaaacc accaaaaaac
     1561 tgcctagaat aaacaaagtg tggaagtatg gcatcagagg atgatgaact tctggtagat
     1621 cttacattaa cacccgtcaa aataagacat tactgtccat caaacttctc atgatgcttc
     1681 tgcaagtctg ttcttcactt tggagattgg gataccattg accgcttttt cccctcccca
     1741 tacctgagtg gatgatactg ttaagctatt ggaaaggagt ctgatagtta catggcttgt
     1801 gtatcaaagg gtacttggta cttagattgc atttctatca tgattttgtg aatctcttgc
     1861 atttactttg aatgtcaagt tagattggcc tgttttatag gccacatttt ccttctgatg
     1921 tgtaaaatca tttcccattt tttaaaagtt ttacacaacc aggttactat aggtattcat
     1981 ttaaatttta atataagtag ttttcattca gtgctatgcg gtacatactt aactgttagg
     2041 gcaggactcc caggtttact gtttttacag agatcttagt atttcatcat gtaaataatt
     2101 tacctctccc tgaccttcta tgctttacca ttgcatgata atatcatttc aggttattta
     2161 agagttaaat ccctcaatgc cagtaattat aagtatacac tgaacatggc gttcagcata
     2221 tgctacaaaa tggcactgtg tcctttgcta aaaggcttca agaataatac actagcagtc
     2281 tacacttcga ttgaagaaac aataaaagtc aatgttttta atgctaacta gtccaagata
     2341 gtaatgcaca tgccaaagaa atattaagac acattcctat ggttaggact gaaaatagaa
     2401 ttggtcacct tcttatccca cttcagtatt ttagctgtca ctcttaaatt aagatctacc
     2461 tgttccttta atgctgacag ttgagctact gctgatattt aaaacgtgta taacttaaag
     2521 accttcgact cttttattca ttggtagttt ttccaaaatg aatatggtga tcactgttgg
     2581 aatttactta ggcatcagaa ccttttactt actgatacac taggaacttg tactgtaaag
     2641 cttgtctgcc cattgtgatc ttctttaccc aattgctaaa tatcagaaca tcaaatttaa
     2701 atatgtgagt agaaaaatta acaaatactg tgtaaaagtt ttgtctattt aaaagctgtt
     2761 ctttgtaaaa agttggctct cactagcaca ggtaacattt ttctgtttga agttgttttt
     2821 ttttgtttgc agtaaagttt ggggcagtgg gttctgggct gacttactga aatcagaaag
     2881 tgattgaaac atgcacaacc aaagccaagg ttttcctttt cattcattta gcaaatatgt
     2941 gttgatcctc aagccccatg ccaggtgcat ttgtagctgc tataaaccat ctgaacgtga
     3001 catggtcaag taactgtcaa ctgtgtcagc ataggtactt cttaagttga catgccatta
     3061 tttaggatgc ctctttcatg ttatttgatt attgtgatgg aaattctctt tgtaccacct
     3121 taaattagtt tgttaatcca aagtggagga agacagcaat aaaatgaatc caagtttaaa
     3181 aatgggaaga catagggtaa gagctctcta ttataaaact gattgcattg tgtttcttct
     3241 tacacatcag tatattgcat agctctcaat gaaacattga cgaacttgct aagcttactt
     3301 tttacaaact caaaaaatcc tttaaagggc ataggaaaaa aaatcattca acaataatac
     3361 ccatttgctt ccttagagct atactaaagt atagaatttc aaaacaggac acccttagat
     3421 tttccaccta ttcgtaacat ggacgctgga actcacagga gagctgtctg tggttccaca
     3481 aacatcatat tttttggtga gtgactgtgg ttgtgattac agagcaagaa gtaaggctct
     3541 ccaggcagtg atggctactt caggtatgac taccatgaga gactatgtgg aatttctttt
     3601 atctttggag atgtttgaga agctagtaaa agaattagga atttaaaatt acagggaaaa
     3661 atatgtatgt gaaaagcaat aagtattttg ttctctttgc tatccagatg ctcacactca
     3721 gatatttatt atacagcagc agtctatatt tttaatcatt gcccattaat agacgcagtg
     3781 aaatattttt gaatcaaaca tttggggttt gtatgtgcat ttaaattgtc ttttgtactg
     3841 tatgttactg tttaatttga atattttatc agaactgtct ccctgtgcct ttataatata
     3901 aagttgtttc tgcaactttt aatgatctta ataaagaata ctttaagaac catattttgc
     3961 taactctgtc ttcaactctg caagtttttc ttgagcaaaa aacaaataaa aaattagtta
     4021 att
//
