LOCUS       XM_039100253            8438 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus diaphanous-related formin 2 (Diaph2),
            transcript variant X3, mRNA.
ACCESSION   XM_039100253
VERSION     XM_039100253.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051356.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039100253.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8438
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..8438
                     /gene="Diaph2"
                     /note="diaphanous-related formin 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 9
                     ESTs, 7 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 77 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:317189"
                     /db_xref="RGD:1564399"
     CDS             409..3681
                     /gene="Diaph2"
                     /codon_start=1
                     /product="protein diaphanous homolog 2 isoform X3"
                     /protein_id="XP_038956181.1"
                     /db_xref="GeneID:317189"
                     /db_xref="RGD:1564399"
                     /translation="MEQPGAAASGAGGGGGGEEPGVGRSNKRGTGNRAANEEETKNKP
                     KLRDRITSFRKSAIKKEKPLIQHPTDSQAAMGEVPSAQILHDERSLILSEKEVLDLFE
                     KMMEDMNLNEEKKAPLRDKDFTTKREMVVQYISATAKSIVGSKVMGGLKNNKHEFTLS
                     SQEYVHELRSGISDEKLLNCLESLRVSLTSNPVSWVNNFGYEGLGVLLDVLEKLLDKK
                     QQENIDKKNQYKIIQCLKAFMNNKFGLQRILGDERSLLLLARAIDPKQQNMMTEIVKI
                     LSAICIVGEENILDKLLGGITAAAERNNRERFSPIVEGLENNEALHLQVACMQFINAL
                     VTSPYDLDFRIHLRNEFLRCGLKAMLPSLKEKENDELDIQLRVFEENKEDDLTELSHR
                     LNDIRAEMDDMNEVFHLLYNMLKDTAAEGYLLSILQHFLLIRNDYYIRPQYYKIIEEC
                     VSQIVLHCSGMDPDFKYRQRIDFDFTHLIDACVNKAKVEESEQKAMEFSKKFDEEFTA
                     RQEAQAEIQKRDEKIKELESEIQQLQAQGPGSAFPGPPPPPPLPGAGPCPPPPPPPPP
                     LPGVGPPPPPPLPGTAPPPPPLFGAPLLPPPPGGITPSLPGPVELPYGMKQKKLYNPE
                     VSMKRINWSKIEPRDLSENCVWLKLKEEKYENPDLFAKLALTFPSQMKGQRHGETSEE
                     NRIGPQKKKMKELRILDTKTAQNLSIFLGSYRMPYEEIKNIILEVNEELLSEALIQNL
                     VKYLPEQNVLRELAQLKNEYDDLCEPEQFGVVMSTVNMLRPRLTSILFKLTFEEHVNN
                     IKPSIIAVTLACEELKKSESFNRLLELILLVGNYMNSGSRNAQSLGFKINFLCKIKDT
                     KSADQKTTLLHFLAEICDEQHRDILKFPEELEHVESASKVSAQILKSNLVAMEQSILH
                     LESNIKNFPKAESLHDKFVEKMMSFTQNAREQYDKLSTMHSNMLKLYESLGEYFIFDP
                     NIVTIEEFFGDLNTFRTLFLEALKENHKRKEMEEKSRRAKLAKEKAEQEKLERQKKKK
                     QLIDINKEGDETGVMDNLLEALQSGAAFRDRRKRIPRNPDNRRPTLERSRSRHNGAMP
                     SK"
ORIGIN      
        1 caggcatgct cggtactccg gcccggttag cactaggagt aggaagggct ttcaacgccg
       61 gctggggcga ccgccagccg gcactttgat gaatcacgtg tgttgaggcc gtcttaaaga
      121 gataggcacc tacttttcct ccaccctaaa caccgccccg agggtggagg cgaccgcggt
      181 gattgcagct gcttaggggc agggcttgcc ccagcgctga gtggtggtgg caccggcgtg
      241 gtttgcgtcg gggttgcctg agcttgggga gacccgttgg cctgggagcg gctcttggcg
      301 ggcaaccctt tccgtccgtg gacgcgggac atcctgagcg ctccaagggg tttttgccct
      361 tgaggagact tgggctttct aggcggcagg tgacagggcc ggggaaagat ggagcagccc
      421 ggggcggcgg cgtccggagc tggaggcgga ggcggcggcg aggaacccgg cgtgggccgg
      481 agcaacaagc gaggcacggg gaaccgggcc gccaacgaag aggagacgaa aaacaaaccc
      541 aaattgcgtg accgaattac aagtttcaga aaatctgcca tcaaaaaaga aaaacctctt
      601 attcaacatc ctactgattc tcaagctgcc atgggtgagg ttccatcagc tcagatatta
      661 catgatgaac gatctctgat tttgtctgaa aaggaagttc tggacctctt tgagaaaatg
      721 atggaggata tgaaccttaa tgaagaaaag aaggctcctt tgcgagacaa ggattttacc
      781 accaagcgtg agatggttgt ccagtatatt tctgctactg ccaaatctat agttggaagt
      841 aaagttatgg gtggcctgaa aaacaacaaa catgagttca ccctttcttc acaagagtat
      901 gttcatgaat tgcgatcggg catctcagat gagaaactcc tcaattgcct ggaatctctt
      961 agagtgtcct taaccagcaa tcctgtcagt tgggttaaca actttggcta tgaaggactt
     1021 ggcgtcttac tggatgtgct ggagaaactt ctggacaaaa aacagcaaga aaatatcgac
     1081 aagaagaacc agtacaaaat cattcagtgc ctgaaagcat ttatgaacaa taagtttgga
     1141 ctacaaagga ttctaggtga tgagagaagc cttttactgt tggcaagagc aattgaccca
     1201 aaacaacaga atatgatgac tgaaatagta aaaatccttt ctgctatttg cattgttggg
     1261 gaagagaata ttctggacaa acttttaggg ggcatcactg ctgcagctga acgaaataac
     1321 agagaacgat tttccccaat tgtggaaggc ttagaaaata atgaagcctt gcatctccag
     1381 gtggcctgca tgcaattcat aaatgcactt gtaacttctc catatgatct tgattttcga
     1441 attcatttga ggaatgaatt cctacgttgt ggactaaaag caatgctccc aagtcttaaa
     1501 gagaaagaaa atgatgagct tgatattcag ttaagggtgt ttgaagagaa caaagaagat
     1561 gacctaactg aattatccca ccgtctcaat gacattcgag ctgaaatgga tgatatgaat
     1621 gaagtcttcc atcttcttta taatatgctg aaagacactg ctgctgaagg ttacttatta
     1681 tccattctgc aacattttct gctcatcaga aatgattact atatcaggcc acagtattat
     1741 aaaataattg aggagtgtgt ttcacagata gtgctgcact gcagtggcat ggatccagac
     1801 ttcaagtaca ggcaacgcat agactttgat ttcactcatc tcatagatgc ttgtgtaaac
     1861 aaggcaaaag ttgaagaaag tgagcaaaaa gcaatggaat tttcaaagaa gtttgatgaa
     1921 gaattcacag ctcgtcagga ggctcaagca gagattcaga aaagagatga aaaaatcaaa
     1981 gaactggaat cagaaatcca gcaacttcaa gcccagggac ctggatctgc atttccaggg
     2041 ccacctccac cacctccact accaggtgca gggccatgcc caccacctcc tccaccacca
     2101 cccccactcc caggagtagg tcctcctcca ccaccaccat tgcctggtac tgcaccacca
     2161 ccaccacctt tgtttggagc acctcttcta ccaccacccc ctggaggaat cactccttcc
     2221 ctaccaggac cagttgagct accatatgga atgaagcaga aaaaactgta taaccccgag
     2281 gtatccatga aaaggatcaa ctggtccaag attgagccta gagacttatc tgaaaactgt
     2341 gtttggctaa aacttaaaga agagaagtat gagaatccag atctttttgc aaaattggcc
     2401 ttgacatttc cttcccagat gaaaggccaa aggcatggag agacttcaga agaaaatagg
     2461 attgggcctc aaaagaagaa aatgaaggaa ttaagaattt tggataccaa aacagcccag
     2521 aatctgtcta tcttccttgg ctcttaccgc atgccttatg aggaaataaa gaacattatt
     2581 ttggaggtta atgaagagtt gctcagcgag gccctaattc agaatcttgt gaaatatctt
     2641 cctgagcaga atgtactcag agaactagca cagcttaaga acgaatatga tgatctctgt
     2701 gagcctgagc agtttggtgt tgtgatgagc actgtgaata tgttacggcc tcgtctcaca
     2761 agcatccttt tcaaactcac ctttgaagaa catgtcaaca acatcaaacc aagcatcata
     2821 gcagtaactc ttgcgtgtga agaactgaag aaaagtgaaa gctttaacag actcttagag
     2881 ttgattcttc tggttggaaa ctacatgaac tcaggctcaa ggaatgccca gtctctgggt
     2941 tttaagatca actttctgtg taagatcaaa gacacaaaat cagcagatca aaaaacaact
     3001 cttttgcatt ttcttgctga aatttgtgat gaacaacacc gggatatcct aaaatttcct
     3061 gaagagctgg agcatgtgga aagcgcaagc aaagtttcag ctcaaatact caagagcaac
     3121 cttgtagcga tggagcaaag cattcttcat ctggagagta acatcaagaa tttccccaaa
     3181 gcagagtctc ttcatgataa attcgtggaa aagatgatga gctttacgca gaatgcaaga
     3241 gagcagtatg acaaactgtc caccatgcac agcaatatgt tgaaactgta tgagagtctg
     3301 ggagaatact tcatttttga tccgaacata gtaaccatag aagaattttt tggtgatctc
     3361 aacaccttca gaaccctttt tttggaagca ttgaaagaaa accacaagag aaaagagatg
     3421 gaagagaaga gcaggagggc aaagcttgca aaagagaaag ctgaacaaga gaagctggaa
     3481 cgtcagaaga agaagaagca gctcattgat ataaacaaag agggtgatga gactggagtg
     3541 atggataatc ttctggaagc cctacagtca ggtgcagcat tcagagaccg cagaaagcga
     3601 attccaagga atccagataa cagacggccc actctggaaa gatcacgctc tcgccacaat
     3661 ggagccatgc catccaagtg attcctgtga ccagggagaa tggagacatt taagaaaaca
     3721 aaatcatcca ttttgagagg aacaaatata cacttaatag ttgtagtgga aataaatgca
     3781 tttccacaaa ggtcaaactg atctgggtga aaggatgtgt ttttattgga gtactgcaag
     3841 gacactcatc tgaacttaga tggcattatt agaaaacatt tgttcctctc taaagataca
     3901 tataacttgt cattgtgtat aaagacctaa ctgtgaagat caaagtataa atcatcgaag
     3961 aatcctaagg cttctaccaa cattccagtc tgtcaaataa tttaaaaact gaaattctag
     4021 gtcagaccta cccaccccat ccccccaaaa tagacaaagg gccggggaaa gataggaaga
     4081 atttccaggg tctactttca gctcatctta tgtatatctt gtaaagtcta ggagaaaagg
     4141 tgcactaatg attgggaagg ggcaaatagt acattctaaa agaggcccaa ttcacggtat
     4201 ttagacccca tctcaagtga aagctaatgg attcatctat gtggcagaaa ttaatcttcc
     4261 cattactcta atgtttgagg gcagtgtcgc aggcacttat cattggtaaa actaaaccaa
     4321 agtttagcag aatcctctag atttcaactt tatttaagat gtatttttta attctccata
     4381 ggtatctgcc ttatagaaaa tctttataca gctatttttg agaaaacttc tatactttca
     4441 tgtatgtgct agggatgagc ctgaaattct attgccttta tttagatttt agaggaaaat
     4501 attgattcct agttcttccc tctattactt ctttctcctt tcaccccaga acagaactgc
     4561 agaagagtac agagagaaga aagtgacttt ttaatgcagg aggaaacgtt gggaaggtca
     4621 attggttggt ctctagttct atcccttttc ccactccact ttggtagttg aagaaaatgt
     4681 aattctctct ccccacttcc tattcctcct gtcttctccc tccctcccta tttacctacc
     4741 aagctacctc cttcactccc ttcttctccc accttctccc ttcctatccc tccctctccc
     4801 tccatctcta acgggcgtgc atgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt
     4861 gtgtgtgtgt ttatatctct tacagaagta acccgtaccc tagtaagaag gtaaacctct
     4921 ctgtcatcat catacttact taccttatat tattaataca tttcagtgat gctgccaaaa
     4981 caaagccaac agataaagaa gctcagcctt gttttaaata tttgagagac cagaaattat
     5041 acttaacttg tctattctct tacaatgtgc atttgtaata attggtgtaa tttctctgga
     5101 gtgtaatttc aaaactaatt catgcagatg attgtgattg ctgtaaaaga ttgcttgtat
     5161 gtatatttct tatgcagata attctatttc tattccacca aagcacatta tagacaatta
     5221 aagaaaagaa cacataactg acttggcaag ccttcttcta agacaaggta aaccagtgac
     5281 cagtagcaca cagattcttt ctacggatgt aaagtaattt aaacggttgc ctttcactta
     5341 ttcttacttg ggtattatat ttcaaaatac tctgaagctg ctataagtag agaaatcaga
     5401 aggtaacaat gtctgagttt tttccttttg ttcttatgtg aaaacacaca cacatacata
     5461 cacacatatg atttagaaca taccactttc acacactttt taaacaatca ctatgaagtt
     5521 taggttctac taattgctgt aaataactac tgtatgcatt ttcaatttta caaagtattt
     5581 tctgaaatat tgtggtatgg cttatttgag gttttttagt tttgttttta tagcttttcg
     5641 ggctgtaaaa aattgatctt gaaatgtaaa ctttgactga aatttggggc atttgccctg
     5701 ccatattatc taactggtca aggttgaaat actgatgtat atcacctttt ccagatgtga
     5761 acttgcctta ttttctagtt tgtaaacaaa aattaatgaa gtactattat tgataaatta
     5821 tatatttgta tttaaatgca ttccacgtgc ttttcacaaa cattagaaaa cctttcaggg
     5881 gacagatgca taattaactc attgacttat aatagtcctg ttctggctac ttgcactttt
     5941 tgttttaggt tgaaaggtat catccaaaaa caaaagtaca tagtggtatt ttttaaaaga
     6001 aaaccaaatt aggatgaaat attttatgtg tttttgttta tttctgccac acataaaaaa
     6061 tgcctgtttc tacaactttt tcttcataat attacaaaac aagttaactg attagaatat
     6121 tttcctttgg ctactgtaat gatttaccat cagtcttata gtttaagacc ccaacaattt
     6181 attgttccat ggtcctggag gccagaagct tgacatctgg acatcagacc attcatgcta
     6241 cctccagagg ctgcaacaga ggcccccttc tttgctttgt ccatttccca atggccaatg
     6301 gcattgtgtg gcttgtggcc acatttttct ctgttccttt ttacatcatc ttctctgtgt
     6361 acctgatctc tctcagcctg tcctgttgat ggtggcattt agagactgcc atcttaagac
     6421 aggataatcc tctctgataa caacataccc tgaactttat gatatctcta tgacccttct
     6481 ttcaagcaag ctaacctcca ggttctttcc tagatagttt agctctgtat ttgagatagt
     6541 tgaatgaatc tataaatgtg tgcccgatct tttcatcaca attcaaaagc tggcaggcta
     6601 catccttttc cttagctcca aagtacatct tcacacagaa tttcctcatt ttatcatctt
     6661 tcactcttaa caaaatttac caaatcaagt gttaattcct tcttgacata atggttcttt
     6721 cttcactata tctcttgtct tatttctttt cttgtttcaa attttaattt cctcctatct
     6781 ggttcttctt taaattagta caaaggtagt aagttgcatt atggtatttt catgctttgt
     6841 tgttgttgat gatgatgatg gtggtggtgg tggtggtggt ggtggtggtg gtgatgatga
     6901 tgatgatgat gatgatgatg atgatgatga tccttctgcc ctcgattcta ccactaccca
     6961 ctactttggt cccctagtac ctcccatttc actgtcatgt ctcatatatt ctattccacc
     7021 ccctaagact tcttttcctc agcaaaaaat gaactaacta tacctacaac acttagcctg
     7081 ccaagctcct caattttatc acttacaagg taaagattag ttttgcataa aactgtagga
     7141 gacaattcag ataagttgtt gttcgttttg ttttgttttt gctgctgtat aacaacaact
     7201 gcctttcttc caattcccac tacagtattc atttcctgtt gtgccctcac cggaaatgcc
     7261 tttaatatcc acatttctat cagtggtttg gctcaggcaa tctatagtgt ctctattaag
     7321 tttaccatca acagttgtac caccctccac ccagcatcca attcaaaagc cattttcaca
     7381 tctgtaggta tttttcatag cagtacccca gctcatacta aaatttatat cagatttcta
     7441 tggttactgt aacatattcc cacaaacaca gagggataaa atagtagatt tcttgttctg
     7501 tagtattttt aaggtcacaa atccaaaacc atgctattgg caggagagta ctcctgtgca
     7561 agctctagga gaaaatccat tctttccatc ttttcctgtg attgtcatta ttccttggat
     7621 tgtggcttca tcttactact ctctcttgtt tgacatcttc ccctctgtat atataatcta
     7681 cctctgcttt tctcttgtaa gatagttttg atgacccgtt cagattatct gttataacat
     7741 ttggattttc agagcctaca tttaattaca acttcacata cctgtctaac agaataaggt
     7801 aatatcacag aatcttggaa ttagcacata aatgaacatg tctttggggg ggcataattc
     7861 agccactaca atagtcattg catataaatg tactttatac tttttaaaat gcatccttgg
     7921 tgctcaagcc aaatttaagg ttgttattaa aagctactgt ctacacaggc tactgcatgc
     7981 tttgttacta aatagacaaa aagactattc taaattttgg ttaatacttt cgccactgta
     8041 accaatgagc tgaaaaaaat cactgatcac aactctactc tggtgtatct cttctgcccc
     8101 ctttttttat gaagcctttg ttgaaatatc ttctatcatg cataatgtag gcacaaaact
     8161 acctctgata cagaagggtt ctttacaaac ttcctttaga tattttgaat ccctcagctg
     8221 aagggagagg taaaagcaaa gactgtgttg aatgggtatt gagggagatt gtgtccatag
     8281 caagccacct taaagaaata gttcaagtag cagtaaaact gtcaatttgt gctatcattt
     8341 caccttggaa taaacacctg tatttgcgcc ggaccaataa tgacttgcag tctctgtata
     8401 atgcctacta atccaataaa gcttagatct gcattaaa
//
