LOCUS       NM_001191907            4674 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus DExH-box helicase 57 (Dhx57), mRNA.
ACCESSION   NM_001191907 XM_345625
VERSION     NM_001191907.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4674)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 4674)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Oct 10, 2014 this sequence version replaced NM_001191907.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            Celera genomic sequence because of problems with the reference
            genome in this region. The genomic coordinates used for the
            transcript record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.34182.1,
                                           SRR26643295.24345.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-242               JAXUCZ010000006.1  20485299-20485540
            243-401             JAXUCZ010000006.1  20488292-20488450
            402-587             JAXUCZ010000006.1  20490032-20490217
            588-1426            JAXUCZ010000006.1  20490480-20491318
            1427-1605           JAXUCZ010000006.1  20493385-20493563
            1606-1727           JAXUCZ010000006.1  20496100-20496221
            1728-1923           JAXUCZ010000006.1  20497415-20497610
            1924-2048           JAXUCZ010000006.1  20498494-20498618
            2049-2182           JAXUCZ010000006.1  20500708-20500841
            2183-2237           JAXUCZ010000006.1  20501822-20501876
            2238-2446           JAXUCZ010000006.1  20505000-20505208
            2447-2563           JAXUCZ010000006.1  20507322-20507438
            2564-2660           JAXUCZ010000006.1  20510334-20510430
            2661-2834           JAXUCZ010000006.1  20511524-20511697
            2835-3035           JAXUCZ010000006.1  20512749-20512949
            3036-3312           JAXUCZ010000006.1  20514587-20514863
            3313-3408           JAXUCZ010000006.1  20516214-20516309
            3409-3492           JAXUCZ010000006.1  20516394-20516477
            3493-3627           JAXUCZ010000006.1  20518279-20518413
            3628-3702           JAXUCZ010000006.1  20519632-20519706
            3703-3837           JAXUCZ010000006.1  20520862-20520996
            3838-4038           JAXUCZ010000006.1  20525359-20525559
            4039-4674           JAXUCZ010000006.1  20527921-20528556
FEATURES             Location/Qualifiers
     source          1..4674
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q12"
     gene            1..4674
                     /gene="Dhx57"
                     /note="DExH-box helicase 57"
                     /db_xref="GeneID:366532"
                     /db_xref="RGD:1310340"
     exon            1..242
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..4182
                     /gene="Dhx57"
                     /EC_number="3.6.4.13"
                     /note="DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57;
                     DEAH-box helicase 57"
                     /codon_start=1
                     /product="putative ATP-dependent RNA helicase DHX57"
                     /protein_id="NP_001178836.1"
                     /db_xref="GeneID:366532"
                     /db_xref="RGD:1310340"
                     /translation="MSSSVRRKGKPGKGDGKGSSRGGRGGRGHVNKSHGGGGSGGGGC
                     GGGGGGGSGSRKASNRIWDDGDDFCVFTESKRPSRPCDSNKSKGETRPKWKPKAKVPL
                     QTLHMTSENQEKVKALLRDLQEQGADAGSERGSSGEEEEDAPEGAAEQSWSAGPEPTF
                     LPDCRPWEYIGPEEVEPPLPEFTVSPLAVQKLSRYGFHTEHCQLALRICEGDLGAALE
                     HLLHQCFSETFGERMALSEAAVSVSLDECVEQRQEETLALKSICGEKFIERIQNRVWT
                     IGLELEYLTNKFCKSKQKESNKNVRDTSPETCKFYLKGNCKFGSKCKFKHEVPPHQII
                     GRTERNVNDPHLDAENDTTFLYELQIRFSKDHKYPYQAPLVAFYSTNENLPLACRLHI
                     SEFLYGKALEFAKTSEPVVYSLITLLEEESEIVKLLTHTQHKYSVPPINVPPAPSETR
                     ISKPAYRKPVIPSNTFLSNQMLEGEGLSELEEDADEDEGPAPIVVENESYVNLKKRSY
                     RRCDRPAKSLFAENSKICRQFQMKQASRQFHAILQERQLLPAWEERETILKLLSKHQV
                     VVISGMTGCGKTTQIPQFILDNSLNGPPERVANIICTQPRRISAISVAERVAKERAER
                     VGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDATLQGVTHIIVDEVHERTEESD
                     FLLLVLKDIVMQRATLQVILMSATLDAGLFSKYFSYCPVITIPGRAFPVDQFFLEDAL
                     AVTRYVLQDGSPYMRSMKQIAKERLKARHNRTALEEVEEDLRLALHLQDEEESVKDTI
                     PDQQLDFKQLLVRYKGVSKSVIKTMSVMDFEKVNLELIEALLEWIVDGKHSYPPGAIL
                     VFLPGLAEIKMLYEQLQSNSLFNNRRSHRCVIHPLHSSLSSEEQQAVFVKPPLGVTKI
                     IISTNIAETSITIDDVVYVIDSGKMKEKRYDAGKGMESLEDTFVSQANALQRKGRAGR
                     VASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSTHNLQSVFSRLI
                     EPPHVDSLRASKVRLRDLGALTPDEKLTPLGYHLASLPVDVRIGKLMLLGSIFRCLDP
                     ALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLCAYKGWQLSTKESARA
                     SYNYCRQNFLSGRTLQEMASLKRQFTELLSDIGFVKEGLRAKEIEKRAQGGDGVLDAT
                     GEEANTNAENPKLISAVLCAALYPNVVQVKTPEGKFQKTSSGVVRLQPKSAELKFVTK
                     NDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVSV
                     QLQRGAFVVSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKNPSMDLCTCPRGS
                     RIISMIVKLITTQ"
     exon            243..401
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            402..587
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            588..1426
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1605
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            1606..1727
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            1728..1923
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            1924..2048
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2049..2182
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2183..2237
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2238..2446
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2447..2563
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2564..2660
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2661..2834
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2835..3035
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3036..3312
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3313..3408
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3409..3492
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3493..3627
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3628..3702
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3703..3837
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3838..4038
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            4039..4674
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgaaaatga gttcttcagt gagaagaaaa ggcaagccag gcaaagggga tggaaagggg
       61 tcttctagag gaggaagagg aggcagagga cacgtgaata aatctcatgg gggtggaggt
      121 agtggcggcg gtggctgcgg cggtggcggt ggtggtggca gcggcagtag aaaggcctca
      181 aatagaattt gggatgatgg cgatgacttt tgtgtcttca ctgaatccaa gcgcccgtcc
      241 aggccctgcg acagtaacaa aagcaaagga gaaacacggc ctaagtggaa gcccaaagcc
      301 aaagtgcccc ttcagacgct gcacatgaca tcagagaatc aggagaaggt gaaagccctt
      361 ctgagggacc tgcaggaaca gggtgcggac gcgggatccg aaagaggctc ctccggggag
      421 gaggaagagg acgcgcccga gggcgctgcc gagcagagct ggtcagctgg accagagccg
      481 acctttcttc ccgactgccg tccttgggag tatataggcc cagaagaagt ggagcctcct
      541 cttccggaat ttacagtctc gccactggca gtgcaaaaac tttccaggta tggctttcac
      601 acggagcact gtcagctggc cctgaggatc tgtgagggag acttaggggc agcactagag
      661 caccttctgc accagtgctt ctcggagacg tttggagaga ggatggcact gtctgaggcc
      721 gctgtttctg taagcttgga tgagtgcgtg gagcagagac aggaagagac acttgctctc
      781 aagtccatct gtggagaaaa atttatagaa agaattcaga acagagtctg gaccattgga
      841 ttggaactgg aatatttgac caacaaattc tgcaagtcta agcaaaagga aagtaacaaa
      901 aatgtacggg acacttcacc tgaaacctgt aaattttacc tcaaaggaaa ctgtaaattt
      961 ggatcaaaat gcaaattcaa acatgaagtg cccccacatc agatcattgg gagaacggag
     1021 agaaacgtaa acgaccctca tctggatgct gagaacgaca ccacttttct gtatgagctt
     1081 cagatccgct tttctaaaga ccacaaatac ccctaccagg ctcccctcgt ggcgttttat
     1141 tccaccaatg agaacctacc tctggcttgt cgtttacata tttctgagtt cctttatggc
     1201 aaggccttgg agttcgcaaa aacttcagaa cctgttgtat attctttgat aaccctttta
     1261 gaggaagagt ctgagattgt caagttacta acacacactc aacataagta cagtgttcct
     1321 cccatcaacg tccctccagc accatccgag accagaataa gtaaacctgc ctaccgcaaa
     1381 ccagtgatcc caagtaacac ttttctttct aatcagatgc tggaagggga aggattatca
     1441 gagctggagg aggatgcaga tgaggacgaa ggccctgctc caattgtcgt ggagaatgaa
     1501 agctatgtga accttaagaa aaggagttac agaaggtgtg accggcctgc aaagtcctta
     1561 tttgctgaga acagtaagat ctgcaggcag ttccagatga aacaggcttc cagacagttc
     1621 cacgcaattc tgcaagaaag acagttacta cctgcttggg aagaaagaga aaccattctt
     1681 aaattgttga gcaagcacca agtggttgtc ataagtggta tgactggatg tgggaaaacc
     1741 acacagattc cacagtttat tctggataat tctctgaacg ggccacctga gagggtggca
     1801 aacatcatct gtacccaacc ccgacgaatc tctgcgatct ctgttgctga gcgtgttgct
     1861 aaggaaagag cagaaagagt gggtctgacg gtgggctatc agatccggtt ggaaagtgtc
     1921 aagtcctcag ccaccagact gttatactgc accacaggag tgctgctgag aaggctggaa
     1981 ggggacgcaa ctttgcaggg agtcacccac atcattgttg atgaagtcca tgagaggaca
     2041 gaagaaagtg acttcttact gctagtgtta aaggacattg tgatgcagag agcaactctc
     2101 caggtcattc ttatgagtgc cactctggac gctgggctct tctccaagta tttcagctac
     2161 tgccctgtca tcaccatacc aggtcgtgca tttcctgttg atcagttttt tctggaggat
     2221 gcacttgccg tgaccaggta tgtgttacag gacgggagcc cgtatatgcg ctccatgaaa
     2281 cagattgcga aggaaaggct taaagccagg cacaacagaa ctgcactgga ggaggtggaa
     2341 gaagacctga ggctggccct tcacctccag gacgaggagg agtctgtcaa agacacaata
     2401 cctgatcagc agttagattt caagcagctc ttggtccgtt ataaaggggt gagcaagtcg
     2461 gtcatcaaga caatgtctgt catggatttt gaaaaggtca accttgaatt aatagaggcc
     2521 ttattagagt ggattgtaga cggcaagcac tcctaccctc caggtgctat acttgtgttt
     2581 ttaccagggc tagcggaaat caagatgctt tatgaacagc tacagtctaa ctctctcttc
     2641 aacaacagac gaagtcatcg gtgtgtcatt cacccactgc actcgtcgtt atccagtgaa
     2701 gagcagcagg cggtgtttgt gaaaccccca ctaggtgtga ctaagattat aatttccacc
     2761 aacattgctg agacttccat aaccattgat gacgtcgtgt atgtcatcga ttctgggaag
     2821 atgaaagaaa agagatacga tgccggcaaa gggatggaaa gtctagagga cacttttgtg
     2881 tctcaggcca atgctctgca gagaaaaggc cgagctggcc gagttgcctc tggagtctgc
     2941 ttccacttgt tcacgagcca ccactacaac caccagcttc tgaagcagca gctcccagag
     3001 atccaaaggg tgcccctgga gcagctgtgc ctcagaatta aaattttaga aatgtttagt
     3061 actcacaatc tccaatccgt gttctctcgg ctcattgaac ctccacatgt tgattctctt
     3121 cgtgcctcaa aagtacggtt gcgagacttg ggagccttga ctccggatga aaagctcacc
     3181 cccctgggct atcacttggc ctctctgcct gtggacgtta ggatcggcaa actgatgttg
     3241 ttgggatcaa tcttccgctg cctggaccct gctctcacca ttgctgccag cttggctttt
     3301 aagtcccctt tcgtgtctcc ctgggataag aaagaagagg ccaatcagaa aaagctggaa
     3361 ttcgcatttg caaacagtga ttatctggcc cttctctgtg catataaggg ttggcagctg
     3421 agtacaaaag aaagtgcgcg agcaagttat aattactgca gacagaattt cctgtctggg
     3481 agaactctgc aggaaatggc cagcctcaaa cggcagttca ctgagctgct ttccgatata
     3541 gggtttgtca aagagggact cagagcaaaa gagattgaaa agagagccca agggggagat
     3601 ggtgtcctgg atgccacagg agaggaggct aacacaaatg ctgagaaccc caagctgata
     3661 tcagcagtgc tgtgtgccgc tctgtatcca aatgtagtac aggtcaaaac cccagaagga
     3721 aagttccaga agaccagttc tggagtggtc agactgcagc caaagtcagc tgagctgaag
     3781 ttcgttacca agaatgacgg ctatgtccac attcaccctt cctcagtaaa ctatcaggtc
     3841 agacacttcg acagccccta cctgttgtac catgagaaaa tcaaaacgag ccgggtgttt
     3901 atccgagact gcagcatggt gtctgtgtac cccctagtct tgtttggcgg aggccaagtg
     3961 agtgtgcagc ttcaaagagg ggcattcgtc gtctccttgg atgatgggtg gatccggttc
     4021 gtggcagctt cccaccaggt ggccgaactg gtgaaggaac tccgctgtga gcttgaccag
     4081 ctcctccagg ataaaattaa gaacccaagc atggacctgt gtacctgtcc tagagggtct
     4141 cgaattatca gcatgattgt gaagctgatc accacacagt gagactggcc ggttgcctgc
     4201 tcttcacctc tgttccctgc aaggcacagg agcactccta cctcccacgg aagactgacc
     4261 tggggctgcc cctggggcac agagcctggg ccccacagcc caagagacag tctccacact
     4321 ggtgtttctg aaaacatggg gacactccca gcacaatttg gagtgtcagt ggtaggacag
     4381 tctaaaaccc agcttgtctt tttgtgactg taccaaactg aatgcaattc acctcataac
     4441 tcgagactga atgtttaata caattctgtc ttaatgtatg tattcttccc tcctcctttt
     4501 tattatgcat tgtctgtact taattgatga tccttttctc ttggtttttt actgggcatg
     4561 aggagaaatg tttggttttc cctgtcataa taaaggctta cctgagagaa ctcaaatgaa
     4621 aggaaaaaag aaatcatgtg agtaagaaaa ataaaacttt cattttagac ctgg
//
