LOCUS       NM_001399194            4216 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus DEAH-box helicase 38 (Dhx38), mRNA.
ACCESSION   NM_001399194 XM_006255577
VERSION     NM_001399194.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4216)
  AUTHORS   Chang,T.H., Tung,L., Yeh,F.L., Chen,J.H. and Chang,S.L.
  TITLE     Functions of the DExD/H-box proteins in nuclear pre-mRNA splicing
  JOURNAL   Biochim Biophys Acta 1829 (8), 764-774 (2013)
   PUBMED   23454554
  REMARK    Review article
REFERENCE   2  (bases 1 to 4216)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 4216)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 4216)
  AUTHORS   Jurica,M.S., Licklider,L.J., Gygi,S.R., Grigorieff,N. and
            Moore,M.J.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
REFERENCE   5  (bases 1 to 4216)
  AUTHORS   Zhou,Z. and Reed,R.
  TITLE     Human homologs of yeast prp16 and prp17 reveal conservation of the
            mechanism for catalytic step II of pre-mRNA splicing
  JOURNAL   EMBO J 17 (7), 2095-2106 (1998)
   PUBMED   9524131
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Jan 4, 2022 this sequence version replaced XM_006255577.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.55912.1,
                                           SRR26643285.53697.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-129               JAXUCZ010000019.1  54439295-54439423   c
            130-469             JAXUCZ010000019.1  54436413-54436752   c
            470-657             JAXUCZ010000019.1  54435916-54436103   c
            658-762             JAXUCZ010000019.1  54435192-54435296   c
            763-910             JAXUCZ010000019.1  54434186-54434333   c
            911-1029            JAXUCZ010000019.1  54433962-54434080   c
            1030-1106           JAXUCZ010000019.1  54433746-54433822   c
            1107-1262           JAXUCZ010000019.1  54433185-54433340   c
            1263-1424           JAXUCZ010000019.1  54432542-54432703   c
            1425-1532           JAXUCZ010000019.1  54432248-54432355   c
            1533-1645           JAXUCZ010000019.1  54431794-54431906   c
            1646-1783           JAXUCZ010000019.1  54430494-54430631   c
            1784-1970           JAXUCZ010000019.1  54429954-54430140   c
            1971-2156           JAXUCZ010000019.1  54429647-54429832   c
            2157-2297           JAXUCZ010000019.1  54429302-54429442   c
            2298-2408           JAXUCZ010000019.1  54428856-54428966   c
            2409-2525           JAXUCZ010000019.1  54428645-54428761   c
            2526-2633           JAXUCZ010000019.1  54428383-54428490   c
            2634-2746           JAXUCZ010000019.1  54427895-54428007   c
            2747-2955           JAXUCZ010000019.1  54427075-54427283   c
            2956-3110           JAXUCZ010000019.1  54426828-54426982   c
            3111-3266           JAXUCZ010000019.1  54426324-54426479   c
            3267-3401           JAXUCZ010000019.1  54426099-54426233   c
            3402-3527           JAXUCZ010000019.1  54425796-54425921   c
            3528-3623           JAXUCZ010000019.1  54425268-54425363   c
            3624-3745           JAXUCZ010000019.1  54423634-54423755   c
            3746-4216           JAXUCZ010000019.1  54422418-54422888   c
FEATURES             Location/Qualifiers
     source          1..4216
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..4216
                     /gene="Dhx38"
                     /note="DEAH-box helicase 38"
                     /db_xref="GeneID:292007"
                     /db_xref="RGD:1310345"
     exon            1..129
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            130..469
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..3830
                     /gene="Dhx38"
                     /EC_number="3.6.4.13"
                     /note="DEAH (Asp-Glu-Ala-His) box polypeptide 38"
                     /codon_start=1
                     /product="pre-mRNA-splicing factor ATP-dependent RNA
                     helicase PRP16"
                     /protein_id="NP_001386123.1"
                     /db_xref="GeneID:292007"
                     /db_xref="RGD:1310345"
                     /translation="MEDAGEDASIHRLEGTNLDSQVGGLICKTKSAASEQHVFKAPAP
                     RPSLLGLDLLASLKRREREEKDDGEDKKKSRISSYKDWEESKDDQKDAEEDGDEQAGR
                     SSRRDRHYRSARVETPSHPGGVSEEFWERSRQRERDRREHGVYASSKEDKDRKKEKSR
                     DRDHDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEE
                     DSGYGSSRRSQWETPSPTPSYRDSERSHRPSTRDRDRSVRSKSSDDTPLPTPSYKYNE
                     WADDRRHLGSTPRLSRGRGRREDGEEGIAFDTEEERQQWEDDQRQADRDWYMMDEGYD
                     EFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINEDNERWETNRMLTSGVVHRLE
                     VDEDFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAIIARKGSQT
                     VRKHREQKERRKAQHKHWELAGTKLGDIMGVKKEEEPDKAMTEDGKVDYRTEQKFADH
                     MKEKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLT
                     QYLHQDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTL
                     IKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIV
                     TSATMDADKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHLSGAP
                     GDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYSQLPSDLQAKIFQKAPDGV
                     RKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGR
                     AGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDP
                     PPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEIL
                     LIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCND
                     HFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGIG
                     EYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGP
                     MFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTKI
                     YTPGRKEQGEPMTPRRTPARFGL"
     exon            470..657
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            658..762
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            763..910
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1029
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1106
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1262
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1424
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..1532
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1645
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1783
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            1784..1970
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            1971..2156
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            2157..2297
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            2298..2408
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            2409..2525
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            2526..2633
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            2634..2746
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            2747..2955
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            2956..3110
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            3111..3266
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            3267..3401
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            3402..3527
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            3528..3623
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            3624..3745
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
     exon            3746..4216
                     /gene="Dhx38"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcattatggg acaatgatgg ccgctttcaa acagcggaat ttgcctcttt gaggccatct
       61 gatcaagcgg tggccgctct ggcgtcccca gatcagagac agaaggcctc gagagtcgtg
      121 cttggtgaga caaataagaa cttgtgatgg aggacgctgg tgaggacgcc tccatccatc
      181 gcttggaagg caccaacttg gactctcagg ttggtggcct tatttgcaag accaaaagtg
      241 cagccagtga gcagcatgtc ttcaaagccc ctgctcctcg cccttcattg ctgggactgg
      301 acttactggc gtccctgaaa cggagggagc gagaggagaa ggatgatggg gaggacaaga
      361 aaaagtccag aatctcttcc tacaaagact gggaggagag taaggatgac cagaaggatg
      421 ccgaggagga tggcgatgag caggctggcc gaagtagccg gagagacagg cactaccgat
      481 ctgctcgggt agagactcca tcccaccccg ggggtgtgag tgaagagttt tgggaacgca
      541 gtaggcagag agagcgggat cggagggagc atggagtcta cgcctcatcc aaagaagaca
      601 aggatcggaa gaaggagaaa tcccgggatc gagaccatga ccgcaagaga gacagagatg
      661 agcgggacag aagtaggcac agcagcagat cagaacgaga cggaggctca gagcgcagca
      721 gcagaagaaa tgaaccagag agtcctcgac accgcccaaa agatgcagcc accccttcaa
      781 ggtccacctg ggaggaggag gacagtggct atggctcttc aaggcgctct cagtgggaaa
      841 caccctcccc aacaccttcc tatcgggact ctgagcggag tcatcggccg tccacacgag
      901 atcgagacag gtctgtgagg agcaagtcct cagatgacac accactgccg accccctcct
      961 ataagtacaa cgagtgggct gatgatagaa gacacttggg gtctacccca cgtctgtcca
     1021 ggggccgagg aagacgtgag gatggtgaag aagggattgc atttgacacg gaggaggagc
     1081 ggcagcagtg ggaggacgac cagaggcaag cagaccggga ttggtacatg atggacgagg
     1141 gctatgatga gttccacaac cctctggctt attcctctga ggactacgtg aggcggcggg
     1201 agcagcacct gcacaaacag aagcagaagc gcatttcagc acagcgcagg cagatcaatg
     1261 aggataatga gcgttgggag actaaccgga tgctcaccag cggggtggtc catcggctgg
     1321 aggtggatga ggactttgaa gaggacaacg cggccaaggt gcatctgatg gtgcacaacc
     1381 tggtgcctcc ctttctggat ggacggattg ttttcaccaa gcagccggag cctgtgatcc
     1441 cagtgaagga tgccacctca gacctggcca ttattgctcg gaaaggcagc cagacggtcc
     1501 gcaagcacag ggaacagaaa gaacggagaa aggctcagca caaacactgg gaactggcag
     1561 ggaccaaact aggagacata atgggtgtca aaaaagaaga ggagccagat aaagctatga
     1621 ctgaagatgg gaaagtggac tacaggacag agcagaagtt tgcagatcac atgaaggaga
     1681 aaagtgaggc cagcagtgag tttgcgaaga agaagtcgat cctggagcag aggcaatacc
     1741 tgcccatctt tgctgtacag caggaactcc tcaccatcat cagagacaac agcattgtga
     1801 tcgtggtcgg ggagacgggg agtggcaaga ccactcagct gacccagtac ttgcatcaag
     1861 atgggtacac ggactatggg atgatcgggt gcacacagcc ccggcgtgtg gctgccatgt
     1921 cagtggccaa gagagtcagt gaagagatgg ggggaaacct tggagaagag gtgggttatg
     1981 ccattcgctt tgaagactgc acttctgaaa acaccttgat caaatacatg accgatggga
     2041 tcctgctccg agagtccctg cgggaggctg acctagacca ctacagcgcc atcatcatgg
     2101 atgaggccca tgagcgctcc ctcaacaccg acgtgctctt tgggctgctc cgggaggttg
     2161 tggctcgacg ctcagacctg aagctcattg tcacctcagc tactatggat gcagacaaat
     2221 ttgctgcctt ctttgggaat gtacccatct tccacatccc tgggcgaact tttcctgttg
     2281 acatcctctt cagcaagacc ccacaggagg attatgtgga ggccgcagtg aagcagtcct
     2341 tgcaggtgca cctgtctggg gcccctggag acatccttat cttcatgcct ggccaagagg
     2401 acattgaggt gacgtctgac cagatcgtag agcacctaga ggagctggag aacgcgcctg
     2461 ccttggctgt gctgcccatc tactcccagc tgccgtctga ccttcaggca aaaatcttcc
     2521 agaaggctcc cgatggcgtc cggaagtgca tcgttgctac caacattgct gagacgtctc
     2581 tgactgttga cggcatcatg tttgtcatcg actctggcta ctgcaagtta aaggtcttca
     2641 accccaggat cggcatggat gctctgcaga tctaccccat tagccaggcc aatgccaacc
     2701 agaggtcagg gagagctggc aggacgggcc caggtcagtg tttcaggctc tacacacaga
     2761 gcgcttacaa gaatgagctc ctgactacca ctgtgcctga gatccagagg accaaccttg
     2821 ccaacgtggt gctgctgctc aagtccctgg gggtgcagga cctgctgcag ttccacttca
     2881 tggatccacc cccagaggac aacatgctca actccatgta ccagctgtgg atcctcggag
     2941 ccctggataa cacaggtggt ctcacttcca cggggcggct gatggtggag ttcccactgg
     3001 acccggctct ctccaagatg ctcatcgtgt cttgtgacat gggctgcagc tccgagatcc
     3061 tgctcatcgt ctccatgctc tccgtccctg ccatcttcta caggcccaag ggcagagagg
     3121 aggagagcga tcagatccgg gagaagtttg ctgtccctga gagtgatcac ctgacctacc
     3181 tgaacgtcta cctgcagtgg aagaacaaca attactccac catttggtgc aacgaccact
     3241 tcatccacgc caaggccatg cggaaggtcc gggaggtgcg ggcccagctc aaggatatca
     3301 tggtgcagca gcggatgagc ctggcctcat gtggcactga ctgggacatt gtcaggaagt
     3361 gcatctgtgc tgcctatttc caccaggcag ccaagctcaa gggcattggg gagtatgtga
     3421 acatccgtac agggatgccc tgccacttac accccaccag ctccctcttc ggaatgggtt
     3481 acacccctga ctacattgta tatcacgagc tggtcatgac caccaaggag tacatgcagt
     3541 gtgtgaccgc cgtggatgga gagtggctgg cggagctggg ccccatgttc tacagtgtga
     3601 aacaggcagg caagtctcgg caggagaatc gtcgtcgggc taaagaggag gcctctgcca
     3661 tggaagagga aatggcccta gctgaggagc agctgcgcgc ccggcggcag gagcaggaga
     3721 agcgcagccc gctgggcagt gtcaggtcta caaagatcta cactccagga cggaaagaac
     3781 agggggaacc catgacacct cgccgcacac cagcccgctt tggactgtga gctggggctc
     3841 tcccaggaga agatggcagc caggcgctaa gtccttggct ctccagcctg ggttccctga
     3901 ggacttggac aaaggctttc atctgcgtgt tcatctctgg gtcattgagg tggttcctgc
     3961 tgagtcaggc tctgccccag gaggaggctg tcctaatgct gggcttggca ggagcctggc
     4021 gcaaggccaa taaggagctg cctgagcagc aggaggtggc tgggccatct tatccactct
     4081 acctgtccct aggacgcttg gcagacaagt gcctcgctgt gactgaaact tttttaatcc
     4141 ttgtgtaaag aggcagagaa acgtgtaatt tggtcatcac atgggatttg gaaataaata
     4201 tattatttgt acaatg
//
