LOCUS       NM_001105926            4177 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus DEAH-box helicase 37 (Dhx37), mRNA.
ACCESSION   NM_001105926 XM_001078816 XM_213772
VERSION     NM_001105926.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4177)
  AUTHORS   Martin,R., Straub,A.U., Doebele,C. and Bohnsack,M.T.
  TITLE     DExD/H-box RNA helicases in ribosome biogenesis
  JOURNAL   RNA Biol 10 (1), 4-18 (2013)
   PUBMED   22922795
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Oct 26, 2010 this sequence version replaced NM_001105926.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643289.32253.1,
                                           SRR26643290.41125.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-185               JAXUCZ010000012.1  36856138-36856322
            186-355             JAXUCZ010000012.1  36858629-36858798
            356-468             JAXUCZ010000012.1  36859492-36859604
            469-808             JAXUCZ010000012.1  36860412-36860751
            809-957             JAXUCZ010000012.1  36861150-36861298
            958-1050            JAXUCZ010000012.1  36862002-36862094
            1051-1147           JAXUCZ010000012.1  36863041-36863137
            1148-1261           JAXUCZ010000012.1  36864074-36864187
            1262-1363           JAXUCZ010000012.1  36865053-36865154
            1364-1478           JAXUCZ010000012.1  36865287-36865401
            1479-1574           JAXUCZ010000012.1  36865741-36865836
            1575-1651           JAXUCZ010000012.1  36866082-36866158
            1652-1796           JAXUCZ010000012.1  36867086-36867230
            1797-1873           JAXUCZ010000012.1  36868005-36868081
            1874-2106           JAXUCZ010000012.1  36868297-36868529
            2107-2218           JAXUCZ010000012.1  36869433-36869544
            2219-2325           JAXUCZ010000012.1  36871400-36871506
            2326-2514           JAXUCZ010000012.1  36871604-36871792
            2515-2639           JAXUCZ010000012.1  36871936-36872060
            2640-2756           JAXUCZ010000012.1  36872153-36872269
            2757-2929           JAXUCZ010000012.1  36873087-36873259
            2930-3044           JAXUCZ010000012.1  36874057-36874171
            3045-3182           JAXUCZ010000012.1  36874268-36874405
            3183-3277           JAXUCZ010000012.1  36874588-36874682
            3278-3351           JAXUCZ010000012.1  36874767-36874840
            3352-3449           JAXUCZ010000012.1  36875288-36875385
            3450-4177           JAXUCZ010000012.1  36875518-36876245
FEATURES             Location/Qualifiers
     source          1..4177
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q14"
     gene            1..4177
                     /gene="Dhx37"
                     /note="DEAH-box helicase 37"
                     /db_xref="GeneID:288647"
                     /db_xref="RGD:1306837"
     exon            1..185
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..3535
                     /gene="Dhx37"
                     /EC_number="3.6.4.13"
                     /note="DEAH (Asp-Glu-Ala-His) box polypeptide 37"
                     /codon_start=1
                     /product="probable ATP-dependent RNA helicase DHX37"
                     /protein_id="NP_001099396.2"
                     /db_xref="GeneID:288647"
                     /db_xref="RGD:1306837"
                     /translation="MGKLRRRYNVKGRLQAESRPAKGPEAPPVRLELEDKDVLKGVDA
                     SNALVLPGRKKKKTKAPPPSKKERKPLTKKERKVLQKVLEQKEKKSQRAELLQKLSEV
                     QVSEAEMSLFYTTAKLGTGDRMYHIKERKPDQPAAQGQEKVSSLSGAHRKRHRSSSTE
                     EDSEASEDSEPEEVTADQPRTSTGADLVHPPPATSEIKSPVPTPQPPPPGTSAPPETP
                     ASAPPPALAKPAVFIPVNRTPEMQEERLKLPILAEEQAIMEAVAEHPIVIVCGETGSG
                     KTTQVPQFLYEAGYSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLSHRVVSYQIRYEGN
                     VTEETRIKFMTDGVLLKEIQKDFLLLKYKVVIIDEAHERSVYTDILLGLLSRIVALRA
                     KRHLPLKLLIMSATLRVEDFTQNQRLFTTPPPVIKVESRQFPVTVHFNKRTPLDDYSG
                     ECFRKVCKIHRMLPAGGILVFLTGQAEVHALCRRLRKAFPIRCSQPQEMEEDSAEGMR
                     RFKKSRTRARKAQAMALPQINLDNYSVLPAGEGDEDREAEMDDEEEALGSDLDLDLGD
                     SEANEGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVIATNVAETSLTIPG
                     IKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVF
                     GDFEQFPPPEITRRPVEDLILQMKALNIEKVINFPFPTPPSVEALIAAEELLIALGAL
                     QAPPKQERMKKLQMSQLSCPITALGRTMSTFPVAPRYAKMLALSQQHGCLPYTIAIVA
                     AMTVRELFEELDRPAASEEELAELKGRRTRVAQMKRTWAGQGASLKLGDLMVLLGAVG
                     ACEYAGCSPQFCQANGLRYKAMLEIRRLRGQLTTAVNAVCPEAGLFLDPKMQPPTESQ
                     VTYLRQIMAAGLGDHLARRVQSEDLLDPKWKNAYKTPLLDDPVFIHPSSVLFRELPEF
                     VVYQEIVETTKMYMKGVSTVEIQWIPSLLPSYCQFDAPLEEPAPTYCPESGRVLCHRA
                     SVFYRVGWPLPAVQVDFPEGIDRYKYFARFLLEGQVFRKLASFKSCLLSSPNTMLKTW
                     ARLQPRTETLLRALVAQKADSRDSLLAAWKKNPKYLLAEYCEWLPKAMHGDVEKNWPP
                     TTDR"
     exon            186..355
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            356..468
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            469..808
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            809..957
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1050
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1147
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1261
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1363
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1478
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1574
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            1575..1651
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1796
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            1797..1873
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            1874..2106
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            2107..2218
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2325
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            2326..2514
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            2515..2639
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            2640..2756
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            2757..2929
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            2930..3044
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            3045..3182
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            3183..3277
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            3278..3351
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            3352..3449
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
     exon            3450..4177
                     /gene="Dhx37"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgcgcaacc cggaagtctc gcagcttggt tcaggttccc agagagtttg tctgagtgag
       61 ccacgcgcgt ggcgaaggaa ccatggggaa gctgcgacgc cgctacaacg tgaaggggcg
      121 gctgcaggcg gaatcccggc ccgccaaggg tcctgaagcg cctcccgtgc ggctggagct
      181 ggaggacaag gatgtgttga aaggggtaga tgccagcaac gccctggtgc tgcctgggag
      241 gaagaagaag aagaccaagg cgcctcctcc atccaagaaa gagaggaagc ccctgacgaa
      301 gaaggagagg aaggtgctac agaaggtctt agaacagaag gagaagaaga gccagcgtgc
      361 cgaactgctc cagaaactga gtgaagtcca agtgtcggag gccgaaatga gtctgttcta
      421 caccacagcc aagctaggca ccggggaccg catgtatcat atcaaagaga ggaagcctga
      481 ccagcctgct gcccagggcc aggagaaagt cagtagcctc agtggggccc accggaagcg
      541 ccacaggtca tcatcaacag aggaagactc tgaggcttca gaagattcag agcctgagga
      601 agtcacagct gaccagccta ggaccagcac aggggcagac ctagtgcatc cgccaccagc
      661 tacttctgag atcaagagcc ctgtacccac cccacagccc cctccacctg ggacctctgc
      721 acctccagaa accccagcct ctgccccgcc tccagccctg gccaagccag ctgtgttcat
      781 ccccgtgaac cgcacccctg aaatgcagga ggagcggctc aagctcccga tcctcgctga
      841 agagcaagcc atcatggagg cggtggctga gcaccccatt gtcattgtgt gtggtgagac
      901 cggcagtggg aagactacac aggtgcccca gtttctctac gaagcaggct acagcagtga
      961 ggacagcatc attggtgtca cagaaccccg ccgagtggct gcggtggcca tgtcccagcg
     1021 ggtggccaag gagatgaacc tgtcacatcg ggttgtctcc taccagatcc gctacgaagg
     1081 gaatgtgaca gaagaaacca ggatcaagtt catgacagat ggtgtcctgc tcaaagagat
     1141 ccagaaggac ttcctgctgc tgaaatacaa ggtagtgatc atcgatgaag cccatgagcg
     1201 gagcgtctac acagacatcc ttctcggcct cctgtcccga attgtggctc tccgggccaa
     1261 gaggcacctg ccgcttaagc tgctcatcat gtctgccacg ctccgggtag aggacttcac
     1321 ccagaaccag cggctcttca ccacacctcc cccagtcatc aaggttgagt ctaggcagtt
     1381 ccctgtgacg gtacatttca acaagcggac cccattggat gactacagtg gcgaatgctt
     1441 taggaaggtc tgcaagatcc accggatgct gcctgcaggt ggcatcctgg tgtttctcac
     1501 aggacaggcc gaggtgcatg cactttgccg acggcttagg aaggccttcc ccatccgttg
     1561 ctcccagcca caagaaatgg aagaggactc agcagaaggg atgcggaggt ttaagaagtc
     1621 ccggacaagg gctaggaagg cccaggccat ggccttgccc cagatcaacc tggacaatta
     1681 ctctgtactg ccagccggcg aaggcgatga ggacagggag gcagagatgg acgacgagga
     1741 ggaggccctg ggctctgacc tagatctgga ccttggtgac agtgaggcaa atgaaggtga
     1801 gcagccagat gcctccctgc cccttcacgt gctcccactc tactctttgc tggctcctga
     1861 gaagcaggca caggtcttca aacctcctcc agaggggacg aggctgtgcg ttatagccac
     1921 caatgtggcc gaaacatccc tcaccatccc gggtatcaag tatgtggtag actgtgggaa
     1981 agtcaaaaaa cgctattatg accgagtcac aggtgtgtcc tccttccgtg tcacctgggt
     2041 ctcccaagca tccgctgacc agcgggctgg tcgtgctggc cggacagagc caggccactg
     2101 ctataggctg tattcctcgg ctgttttcgg ggactttgag cagtttcctc ctccagagat
     2161 aacccgcaga ccagtggagg acttgatcct gcaaatgaaa gcgctcaaca ttgagaaggt
     2221 catcaacttc ccgttcccca cacctccgtc cgtggaggcc ctcattgctg cggaagagct
     2281 gctgattgcc ctgggggccc tgcaggcgcc tccgaaacag gaaagaatga agaagctaca
     2341 gatgtcacag ctgagctgcc ccatcaccgc gctggggcgg accatgtcca ccttccccgt
     2401 ggcaccccgc tatgccaaga tgctggcact gagccagcag cacggctgcc tgccctacac
     2461 cattgccatt gtagctgcca tgactgtgcg tgagctgttt gaggagctgg acagacctgc
     2521 tgccagtgaa gaggagcttg cagagctgaa gggccgtcga acccgtgtgg cccagatgaa
     2581 gaggacctgg gccgggcagg gggcttctct gaagcttggc gacctcatgg tgttgctggg
     2641 tgctgtggga gcctgtgagt acgctggctg ctcaccccag ttctgccaag ctaacggact
     2701 gcgctacaag gccatgctag agatccggcg cctgcgtggc cagctgacca ccgcagtcaa
     2761 tgccgtgtgc ccggaggccg ggcttttcct ggaccccaaa atgcagcctc ctaccgagag
     2821 ccaggtgacc tacctgcgac aaatcatggc agctggtctg ggtgaccacc tggcccgccg
     2881 ggttcagagt gaggacctgc tggaccccaa gtggaagaat gcctacaaga cccctcttct
     2941 agatgacccc gtcttcatcc accccagctc tgttctcttc agagagttgc ctgagttcgt
     3001 ggtctaccag gaaattgtgg agaccaccaa gatgtacatg aaaggtgtct ccactgtgga
     3061 aatccagtgg atcccttccc tgctgccctc ctactgccag ttcgacgcgc ccttggagga
     3121 gccagccccc acttactgtc cagagtcagg acgggtgctg tgccaccggg ccagcgtgtt
     3181 ctaccgcgtg ggctggccac tccctgccgt ccaggtggac ttccctgaag gcattgaccg
     3241 ctacaagtac tttgcacggt ttctgctgga gggacaggtc ttccgaaagt tggcttcatt
     3301 caagagctgc ctgctatcta gccccaacac catgctgaag acttgggcca ggctgcagcc
     3361 caggacagag accctattga gagcccttgt ggcccagaag gctgattccc gtgattccct
     3421 gctggctgca tggaagaaaa accccaaata cctgctggcc gagtactgtg agtggctccc
     3481 aaaggctatg cacggcgacg ttgagaagaa ctggccccct accaccgacc gctgaccaca
     3541 cacccagctg tacagtcggc cagcatctag gctgttacca agaggccagc tcacagctac
     3601 actgaccagg agtgccttct ttgtgactgt tagaagacag acagacgtgg ttcatcttcc
     3661 acatttctcc ctgtctaaag aggaatcttc aggtgacatt agagcctgtg gatgcagagc
     3721 tactctggga caggagagtg aggagagtgg accttcccca gagcacctgt gcggccagcc
     3781 tcatagcgag cgtctgggca gcagcaggcg cattgcagac gcctgtgacc cagtgacttt
     3841 cctgaaaggt tggccccaga gctctgctcc acacaggagg aagctggttt ccaggccctg
     3901 ctttggcagc agtaggcagc tgtctttagg agctgctctt gctgggtatg accagtgagc
     3961 ctgtggcctc ggctggtaag gtcacaaacg caaggccagc ctgagctaca cagcaagact
     4021 gtcttctgtc tgtttttcaa gacaggattt ctctgtataa ccctggctat cctggaactg
     4081 cgcctgtaga ccaggctgtc ctcaaactca gagatccccc ttcctccgcc tgccttaaat
     4141 actgggatta aaggtgtgtg tcaccaccgc ccaataa
//
